A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice

Biochemical and Biophysical Research Communications

Volumn 367, Issue 4, 2008, Pages 859-865

  Dinkova Kostova, Albena T ^a,b   Jenkins, Stephanie N ^a   Wehage, Scott L ^a   Huso, David L ^a   Benedict, Andrea L ^a   Stephenson, Katherine K ^a   Fahey, Jed W ^a   Liu, Hua ^a   Liby, Karen T ^c   Honda, Tadashi ^d   Gribble, Gordon W ^d   Sporn, Michael B ^c   Talalay, Paul ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d Dartmouth College   (United States)

Author keywords

2 cyano 3,12 dioxooleana 1,9(11) dien 28 onitrile; Heme oxygenase 1; NQO1; SKH 1 hairless mouse

Indexed keywords

2 CYANO 3,12 DIOXOOLEANA 1,9(11) DIEN 28 ONITRILE; HEME OXYGENASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRITERPENOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN CANCER; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR VOLUME; ULTRAVIOLET B RADIATION;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOPROTECTION; FEMALE; HEME OXYGENASE-1; MICE; MICE, INBRED HRS; NADPH DEHYDROGENASE; NEOPLASMS, RADIATION-INDUCED; SKIN NEOPLASMS; TRITERPENES; ULTRAVIOLET RAYS;

MUS;

EID: 38649113886     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.01.026     Document Type: Article

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