메뉴 건너뛰기




Volumn 51, Issue 2, 2008, Pages 232-238

Novel role of protein kinase C-δ Tyr311 phosphorylation in vascular smooth muscle cell hypertrophy by angiotensin II

Author keywords

Angiotensin II; AT1 receptor; Hypertrophy; Protein kinase C ; Signal transduction; Src; Vascular smooth muscle cells

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ANGIOTENSIN II; PROTEIN KINASE C DELTA; TYROSINE;

EID: 38549167929     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.101253     Document Type: Article
Times cited : (33)

References (59)
  • 1
    • 0033635110 scopus 로고    scopus 로고
    • Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells
    • Touyz RM, Schiffrin EL. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev. 2000;52:639-672.
    • (2000) Pharmacol Rev , vol.52 , pp. 639-672
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 2
    • 33846362954 scopus 로고    scopus 로고
    • Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
    • Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol. 2006;292:C82-C97.
    • (2006) Am J Physiol Cell Physiol , vol.292
    • Mehta, P.K.1    Griendling, K.K.2
  • 3
    • 0030892639 scopus 로고    scopus 로고
    • Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells
    • Liao DF, Monia B, Dean N, Berk BC. Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells. J Biol Chem. 1997;272:6146-6150.
    • (1997) J Biol Chem , vol.272 , pp. 6146-6150
    • Liao, D.F.1    Monia, B.2    Dean, N.3    Berk, B.C.4
  • 5
    • 33644857156 scopus 로고    scopus 로고
    • Angiotensin II regulates vascular and endothelial dysfunction: Recent topics of Angiotensin II type-1 receptor signaling in the vasculature
    • Nakashima H, Suzuki H, Ohtsu H, Chao JY, Utsunomiya H, Frank GD, Eguchi S. Angiotensin II regulates vascular and endothelial dysfunction: recent topics of Angiotensin II type-1 receptor signaling in the vasculature. Curr Vasc Pharmacol. 2006;4:67-78.
    • (2006) Curr Vasc Pharmacol , vol.4 , pp. 67-78
    • Nakashima, H.1    Suzuki, H.2    Ohtsu, H.3    Chao, J.Y.4    Utsunomiya, H.5    Frank, G.D.6    Eguchi, S.7
  • 6
    • 0037409235 scopus 로고    scopus 로고
    • Angiotensin II signaling pathways mediated by tyrosine kinases
    • Yin G, Yan C, Berk BC. Angiotensin II signaling pathways mediated by tyrosine kinases. Int J Biochem Cell Biol. 2003;35:780-783.
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 780-783
    • Yin, G.1    Yan, C.2    Berk, B.C.3
  • 7
    • 34247113814 scopus 로고    scopus 로고
    • Angiotensin II signal transduction through the AT1 receptor: Novel insights into mechanisms and pathophysiology
    • Higuchi S, Ohtsu H, Suzuki H, Shirai H, Frank GD, Eguchi S. Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology. Clin Sci (Lond). 2007;112:417-428.
    • (2007) Clin Sci (Lond) , vol.112 , pp. 417-428
    • Higuchi, S.1    Ohtsu, H.2    Suzuki, H.3    Shirai, H.4    Frank, G.D.5    Eguchi, S.6
  • 8
    • 0035861760 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells
    • Wakino S, Kintscher U, Liu Z, Kim S, Yin F, Ohba M, Kuroki T, Schonthal AH, Hsueh WA, Law RE. Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells. J Biol Chem. 2001;276:47650-47657.
    • (2001) J Biol Chem , vol.276 , pp. 47650-47657
    • Wakino, S.1    Kintscher, U.2    Liu, Z.3    Kim, S.4    Yin, F.5    Ohba, M.6    Kuroki, T.7    Schonthal, A.H.8    Hsueh, W.A.9    Law, R.E.10
  • 9
    • 4944256273 scopus 로고    scopus 로고
    • Proteomic and metabolomic analysis of vascular smooth muscle cells: Role of PKCdelta
    • Mayr M, Siow R, Chung YL, Mayr U, Griffiths JR, Xu Q. Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta. Circ Res. 2004;94:e87-e96.
    • (2004) Circ Res , vol.94
    • Mayr, M.1    Siow, R.2    Chung, Y.L.3    Mayr, U.4    Griffiths, J.R.5    Xu, Q.6
  • 10
    • 27444433826 scopus 로고    scopus 로고
    • Protein kinase C delta induces apoptosis of vascular smooth muscle cells through induction of the tumor suppressor p53 by both p38-dependent and p38-independent mechanisms
    • Ryer EJ, Sakakibara K, Wang C, Sarkar D, Fisher PB, Faries PL, Kent KC, Liu B. Protein kinase C delta induces apoptosis of vascular smooth muscle cells through induction of the tumor suppressor p53 by both p38-dependent and p38-independent mechanisms. J Biol Chem. 2005;280:35310-35317.
    • (2005) J Biol Chem , vol.280 , pp. 35310-35317
    • Ryer, E.J.1    Sakakibara, K.2    Wang, C.3    Sarkar, D.4    Fisher, P.B.5    Faries, P.L.6    Kent, K.C.7    Liu, B.8
  • 11
  • 12
    • 0642303674 scopus 로고    scopus 로고
    • Mechanical stress-activated PKCdelta regulates smooth muscle cell migration
    • Li C, Wernig F, Leitges M, Hu Y, Xu Q. Mechanical stress-activated PKCdelta regulates smooth muscle cell migration. FASEB J. 2003;17:2106-2108.
    • (2003) FASEB J , vol.17 , pp. 2106-2108
    • Li, C.1    Wernig, F.2    Leitges, M.3    Hu, Y.4    Xu, Q.5
  • 13
    • 0037160074 scopus 로고    scopus 로고
    • Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src
    • Saito S, Frank GD, Mifune M, Ohba M, Utsunomiya H, Motley ED, Inagami T, Eguchi S. Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src. J Biol Chem. 2002;277:44695-44700.
    • (2002) J Biol Chem , vol.277 , pp. 44695-44700
    • Saito, S.1    Frank, G.D.2    Mifune, M.3    Ohba, M.4    Utsunomiya, H.5    Motley, E.D.6    Inagami, T.7    Eguchi, S.8
  • 14
    • 0037371354 scopus 로고    scopus 로고
    • Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: Role of metalloprotease and protein kinase C-delta
    • Frank GD, Mifune M, Inagami T, Ohba M, Sasaki T, Higashiyama S, Dempsey PJ, Eguchi S. Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta. Mol Cell Biol. 2003;23:1581-1589.
    • (2003) Mol Cell Biol , vol.23 , pp. 1581-1589
    • Frank, G.D.1    Mifune, M.2    Inagami, T.3    Ohba, M.4    Sasaki, T.5    Higashiyama, S.6    Dempsey, P.J.7    Eguchi, S.8
  • 16
    • 1842454982 scopus 로고    scopus 로고
    • The enigmatic protein kinase Cdelta: Complex roles in cell proliferation and survival
    • Jackson DN, Foster DA. The enigmatic protein kinase Cdelta: complex roles in cell proliferation and survival. FASEB J. 2004;18:627-636.
    • (2004) FASEB J , vol.18 , pp. 627-636
    • Jackson, D.N.1    Foster, D.A.2
  • 17
    • 10944238407 scopus 로고    scopus 로고
    • Distinctive activation mechanisms and functions for protein kinase Cdelta
    • Steinberg SF. Distinctive activation mechanisms and functions for protein kinase Cdelta. Biochem J. 2004;384:449-459.
    • (2004) Biochem J , vol.384 , pp. 449-459
    • Steinberg, S.F.1
  • 18
    • 10644228773 scopus 로고    scopus 로고
    • Angiotensin II-induced protein kinase D activation is regulated by protein kinase Cdelta and mediated via the angiotensin II type 1 receptor in vascular smooth muscle cells
    • Tan M, Xu X, Ohba M, Cui MZ. Angiotensin II-induced protein kinase D activation is regulated by protein kinase Cdelta and mediated via the angiotensin II type 1 receptor in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004;24:2271-2276.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2271-2276
    • Tan, M.1    Xu, X.2    Ohba, M.3    Cui, M.Z.4
  • 20
    • 0037110732 scopus 로고    scopus 로고
    • Nuclear import of PKCdelta is required for apoptosis: Identification of a novel nuclear import sequence
    • DeVries TA, Neville MC, Reyland ME. Nuclear import of PKCdelta is required for apoptosis: identification of a novel nuclear import sequence. EMBO J. 2002;21:6050-6060.
    • (2002) EMBO J , vol.21 , pp. 6050-6060
    • DeVries, T.A.1    Neville, M.C.2    Reyland, M.E.3
  • 21
    • 12544257436 scopus 로고    scopus 로고
    • ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx
    • Sanderson MP, Erickson SN, Gough PJ, Garton KJ, Wille PT, Raines EW, Dunbar AJ, Dempsey PJ. ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx. J Biol Chem. 2005;280:1826-1837.
    • (2005) J Biol Chem , vol.280 , pp. 1826-1837
    • Sanderson, M.P.1    Erickson, S.N.2    Gough, P.J.3    Garton, K.J.4    Wille, P.T.5    Raines, E.W.6    Dunbar, A.J.7    Dempsey, P.J.8
  • 24
    • 0031813150 scopus 로고    scopus 로고
    • Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C
    • Ohba M, Ishino K, Kashiwagi M, Kawabe S, Chida K, Huh NH, Kuroki T. Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C. Mol Cell Biol. 1998;18:5199-5207.
    • (1998) Mol Cell Biol , vol.18 , pp. 5199-5207
    • Ohba, M.1    Ishino, K.2    Kashiwagi, M.3    Kawabe, S.4    Chida, K.5    Huh, N.H.6    Kuroki, T.7
  • 29
    • 0347419296 scopus 로고    scopus 로고
    • Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling
    • Eguchi S, Frank GD, Mifune M, Inagami T. Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling. Biochem Soc Trans. 2003;31:1198-1202.
    • (2003) Biochem Soc Trans , vol.31 , pp. 1198-1202
    • Eguchi, S.1    Frank, G.D.2    Mifune, M.3    Inagami, T.4
  • 30
    • 0032510977 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy
    • Ushio-Fukai M, Alexander RW, Akers M, Griendling KK. p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. J Biol Chem. 1998;273:15022-15029.
    • (1998) J Biol Chem , vol.273 , pp. 15022-15029
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Griendling, K.K.4
  • 31
    • 0033529675 scopus 로고    scopus 로고
    • Reactive oxygen species mediate the activation of Akt/ protein kinase B by angiotensin II in vascular smooth muscle cells
    • Ushio-Fukai M, Alexander RW, Akers M, Yin Q, Fujio Y, Walsh K, Griendling KK. Reactive oxygen species mediate the activation of Akt/ protein kinase B by angiotensin II in vascular smooth muscle cells. J Biol Chem. 1999;274:22699-22704.
    • (1999) J Biol Chem , vol.274 , pp. 22699-22704
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Yin, Q.4    Fujio, Y.5    Walsh, K.6    Griendling, K.K.7
  • 32
    • 33750602514 scopus 로고    scopus 로고
    • Angiotensin II signal transduction through small GTP-binding proteins: Mechanism and significance in vascular smooth muscle cells
    • Ohtsu H, Suzuki H, Nakashima H, Dhobale S, Frank GD, Motley ED, Eguchi S. Angiotensin II signal transduction through small GTP-binding proteins: mechanism and significance in vascular smooth muscle cells. Hypertension. 2006;48:534-540.
    • (2006) Hypertension , vol.48 , pp. 534-540
    • Ohtsu, H.1    Suzuki, H.2    Nakashima, H.3    Dhobale, S.4    Frank, G.D.5    Motley, E.D.6    Eguchi, S.7
  • 33
    • 26844471162 scopus 로고    scopus 로고
    • Angiotensin II-induced activation of P21-activated kinase 1 requires Ca2+ and protein kinase C {delta} in vascular smooth muscle cells
    • Woolfolk EA, Eguchi S, Ohtsu H, Nakashima H, Ueno H, Gerthoffer WT, Motley ED. Angiotensin II-induced activation of P21-activated kinase 1 requires Ca2+ and protein kinase C {delta} in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2005;289:C1286-C1294.
    • (2005) Am J Physiol Cell Physiol , vol.289
    • Woolfolk, E.A.1    Eguchi, S.2    Ohtsu, H.3    Nakashima, H.4    Ueno, H.5    Gerthoffer, W.T.6    Motley, E.D.7
  • 34
    • 0029891057 scopus 로고    scopus 로고
    • Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensitive tyrosine kinase
    • Eguchi S, Matsumoto T, Motley ED, Utsunomiya H, Inagami T. Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensitive tyrosine kinase. J Biol Chem. 1996;271:14169-14175.
    • (1996) J Biol Chem , vol.271 , pp. 14169-14175
    • Eguchi, S.1    Matsumoto, T.2    Motley, E.D.3    Utsunomiya, H.4    Inagami, T.5
  • 35
    • 18244407290 scopus 로고    scopus 로고
    • Cardiovascular and renal regulation by the angiotensin type 2 receptor: The AT2 receptor comes of age
    • Carey RM. Cardiovascular and renal regulation by the angiotensin type 2 receptor: the AT2 receptor comes of age. Hypertension. 2005;45:840-844.
    • (2005) Hypertension , vol.45 , pp. 840-844
    • Carey, R.M.1
  • 36
    • 2442568463 scopus 로고    scopus 로고
    • Cardiovascular and renal function of angiotensin II type-2 receptors
    • Johren O, Dendorfer A, Dominiak P. Cardiovascular and renal function of angiotensin II type-2 receptors. Cardiovasc Res. 2004;62:460-467.
    • (2004) Cardiovasc Res , vol.62 , pp. 460-467
    • Johren, O.1    Dendorfer, A.2    Dominiak, P.3
  • 38
    • 2442498430 scopus 로고    scopus 로고
    • Stimulus-specific differences in protein kinase C delta localization and activation mechanisms in cardiomyocytes
    • Rybin VO, Guo J, Sabri A, Elouardighi H, Schaefer E, Steinberg SF. Stimulus-specific differences in protein kinase C delta localization and activation mechanisms in cardiomyocytes. J Biol Chem. 2004;279:19350-19361.
    • (2004) J Biol Chem , vol.279 , pp. 19350-19361
    • Rybin, V.O.1    Guo, J.2    Sabri, A.3    Elouardighi, H.4    Schaefer, E.5    Steinberg, S.F.6
  • 39
    • 0032474741 scopus 로고    scopus 로고
    • Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: Regulation of Src family kinase activity by protein kinase C-delta
    • Song JS, Swann PG, Szallasi Z, Blank U, Blumberg PM, Rivera J. Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta. Oncogene. 1998;16:3357-3368.
    • (1998) Oncogene , vol.16 , pp. 3357-3368
    • Song, J.S.1    Swann, P.G.2    Szallasi, Z.3    Blank, U.4    Blumberg, P.M.5    Rivera, J.6
  • 41
    • 0031882754 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells
    • Ishida M, Ishida T, Thomas SM, Berk BC. Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells. Circ Res. 1998;82:7-12.
    • (1998) Circ Res , vol.82 , pp. 7-12
    • Ishida, M.1    Ishida, T.2    Thomas, S.M.3    Berk, B.C.4
  • 42
    • 0036179708 scopus 로고    scopus 로고
    • Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats
    • Touyz RM, Wu XH, He G, Salomon S, Schiffrin EL. Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension. 2002;39:479-485.
    • (2002) Hypertension , vol.39 , pp. 479-485
    • Touyz, R.M.1    Wu, X.H.2    He, G.3    Salomon, S.4    Schiffrin, E.L.5
  • 43
    • 15044347565 scopus 로고    scopus 로고
    • Src family kinase involvement in rat preglomerular microvascular contractile and [Ca2+]i responses to ANG II
    • Che Q, Carmines PK. Src family kinase involvement in rat preglomerular microvascular contractile and [Ca2+]i responses to ANG II. Am J Physiol Renal Physiol. 2005;288:F658-664.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Che, Q.1    Carmines, P.K.2
  • 44
    • 34548511124 scopus 로고    scopus 로고
    • Rottlerin: An inappropriate and ineffective inhibitor of PKCdelta
    • Soltoff SP. Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta. Trends Pharmacol Sci. 2007;28:453-458.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 453-458
    • Soltoff, S.P.1
  • 47
    • 0030973402 scopus 로고    scopus 로고
    • Protein kinase C delta inhibits the proliferation of vascular smooth muscle cells by suppressing G1 cyclin expression
    • Fukumoto S, Nishizawa Y, Hosoi M, Koyama H, Yamakawa K, Ohno S, Morii H. Protein kinase C delta inhibits the proliferation of vascular smooth muscle cells by suppressing G1 cyclin expression. J Biol Chem. 1997;272:13816-13822.
    • (1997) J Biol Chem , vol.272 , pp. 13816-13822
    • Fukumoto, S.1    Nishizawa, Y.2    Hosoi, M.3    Koyama, H.4    Yamakawa, K.5    Ohno, S.6    Morii, H.7
  • 48
    • 16244362671 scopus 로고    scopus 로고
    • Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
    • Fink SL, Cookson BT. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect Immun. 2005;73:1907-1916.
    • (2005) Infect Immun , vol.73 , pp. 1907-1916
    • Fink, S.L.1    Cookson, B.T.2
  • 49
    • 0037031487 scopus 로고    scopus 로고
    • Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells
    • Rahman A, True AL, Anwar KN, Ye RD, Voyno-Yasenetskaya TA, Malik AB. Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells. Circ Res. 2002;91:398-405.
    • (2002) Circ Res , vol.91 , pp. 398-405
    • Rahman, A.1    True, A.L.2    Anwar, K.N.3    Ye, R.D.4    Voyno-Yasenetskaya, T.A.5    Malik, A.B.6
  • 50
    • 1842582001 scopus 로고    scopus 로고
    • Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex
    • Kajimoto T, Shirai Y, Sakai N, Yamamoto T, Matsuzaki H, Kikkawa U, Saito N. Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex. J Biol Chem. 2004;279:12668-12676.
    • (2004) J Biol Chem , vol.279 , pp. 12668-12676
    • Kajimoto, T.1    Shirai, Y.2    Sakai, N.3    Yamamoto, T.4    Matsuzaki, H.5    Kikkawa, U.6    Saito, N.7
  • 51
    • 33748597111 scopus 로고    scopus 로고
    • Protein kinase Cdelta participates in insulin-induced activation of PKB via PDK1
    • Brand C, Cipok M, Attali V, Bak A, Sampson SR. Protein kinase Cdelta participates in insulin-induced activation of PKB via PDK1. Biochem Biophys Res Commun. 2006;349:954-962.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 954-962
    • Brand, C.1    Cipok, M.2    Attali, V.3    Bak, A.4    Sampson, S.R.5
  • 52
    • 0027190997 scopus 로고
    • Angiotensin II stimulates increased protein synthesis, not increased DNA synthesis, in intact rat aortic segments, in vitro
    • Holycross BJ, Peach MJ, Owens GK. Angiotensin II stimulates increased protein synthesis, not increased DNA synthesis, in intact rat aortic segments, in vitro. J Vasc Res. 1993;30:80-86.
    • (1993) J Vasc Res , vol.30 , pp. 80-86
    • Holycross, B.J.1    Peach, M.J.2    Owens, G.K.3
  • 53
    • 0023916169 scopus 로고
    • Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells
    • Geisterfer AA, Peach MJ, Owens GK. Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ Res. 1988;62:749-756.
    • (1988) Circ Res , vol.62 , pp. 749-756
    • Geisterfer, A.A.1    Peach, M.J.2    Owens, G.K.3
  • 54
    • 0039765390 scopus 로고    scopus 로고
    • Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta
    • Fujii T, Garcia-Bermejo ML, Bernabo JL, Caamano J, Ohba M, Kuroki T, Li L, Yuspa SH, Kazanietz MG. Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta. J Biol Chem. 2000;275:7574-7582.
    • (2000) J Biol Chem , vol.275 , pp. 7574-7582
    • Fujii, T.1    Garcia-Bermejo, M.L.2    Bernabo, J.L.3    Caamano, J.4    Ohba, M.5    Kuroki, T.6    Li, L.7    Yuspa, S.H.8    Kazanietz, M.G.9
  • 55
    • 0035839635 scopus 로고    scopus 로고
    • PKCdelta is required for mitochondrial-dependent apoptosis in salivary epithelial cells
    • Matassa AA, Carpenter L, Biden TJ, Humphries MJ, Reyland ME. PKCdelta is required for mitochondrial-dependent apoptosis in salivary epithelial cells. J Biol Chem. 2001;276:29719-29728.
    • (2001) J Biol Chem , vol.276 , pp. 29719-29728
    • Matassa, A.A.1    Carpenter, L.2    Biden, T.J.3    Humphries, M.J.4    Reyland, M.E.5
  • 56
    • 33847072066 scopus 로고    scopus 로고
    • Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin
    • Motley ED, Eguchi K, Patterson MM, Palmer PD, Suzuki H, Eguchi S. Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin. Hypertension. 2007;49:577-583.
    • (2007) Hypertension , vol.49 , pp. 577-583
    • Motley, E.D.1    Eguchi, K.2    Patterson, M.M.3    Palmer, P.D.4    Suzuki, H.5    Eguchi, S.6
  • 57
    • 33846849099 scopus 로고    scopus 로고
    • Proteomics and metabolomics combined in cardiovascular research
    • Mayr M, Madhu B, Xu Q. Proteomics and metabolomics combined in cardiovascular research. Trends Cardiovasc Med. 2007;17:43-48.
    • (2007) Trends Cardiovasc Med , vol.17 , pp. 43-48
    • Mayr, M.1    Madhu, B.2    Xu, Q.3
  • 58
    • 0035570685 scopus 로고    scopus 로고
    • Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice
    • Kanwar RK, Kanwar JR, Wang D, Ormrod DJ, Krissansen GW. Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol. 2001;21:1991-1997.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1991-1997
    • Kanwar, R.K.1    Kanwar, J.R.2    Wang, D.3    Ormrod, D.J.4    Krissansen, G.W.5
  • 59


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.