β-Melanocyte-stimulating hormone potently reduces appetite via the hypothalamus in chicks

Journal of Neuroendocrinology

Volumn 20, Issue 2, 2008, Pages 220-226

  Smith, M L ^a   Prall, B ^b   Nandar, W ^b   Cline, Mark A ^b  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RADFORD UNIVERSITY   (United States)

Author keywords

MSH; Appetite; Behavior; Chick; Corticosterone; Feeding

Indexed keywords

BETA INTERMEDIN; CORTICOSTERONE;

ANIMAL EXPERIMENT; ANOREXIA; ANTERIOR HYPOTHALAMUS; APPETITE; ARTICLE; CHICK; CORTICOSTERONE BLOOD LEVEL; FEEDING BEHAVIOR; FLUID INTAKE; FOOD INTAKE; HORMONE ACTION; HYPOTHALAMUS FUNCTION; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; NONHUMAN; PRIORITY JOURNAL; SATIETY;

ALPHA-MSH; ANIMALS; ANIMALS, NEWBORN; APPETITE; BETA-MSH; CHICKENS; CORTICOSTERONE; DRINKING; EATING; FEEDING BEHAVIOR; FOOD DEPRIVATION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; OSMOLAR CONCENTRATION;

EID: 38549155641     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2007.01639.x     Document Type: Article

References (35)

1. Smith PE. Experimental ablation of the hypophysis in the frog embryo. Science 1916; 44: 280-282.
2. Wikberg JES. Melanocortin receptors: Perspectives for novel drugs. Eur J Pharmacol 1999; 375: 295-310.
3. Gantz I, Fong TM. The melanocortin system. Am J Physiol Endocrinol Metab 2003; 284: E468-E474.
4. Kask A, Rago L, Wikberg JES, Schioth HB. Differential effects of melanocortin peptides on ingestive behaviour in rats: Evidence against the involvement of MC3 receptor in the regulation of food intake. Neurosci Lett 2000; 283: 1-4.
5. 2 -melanocyte stimulating hormones on hypothalamic neuronal activation and feeding in the rat. Neuroscience 2001; 108: 437-445.
6. Butler AA, Kesterson RA, Khong K, Cullen MJ, Pelleymounter MA, Dekoning J, Baetscher M, Cone RD. A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse. Endocrinology 2000; 141: 3518-3521.
7. Takeuchi S, Takahashi S. A possible involvement of melanocortin 3 receptor in the regulation of adrenal gland function in the chicken. Biochim Biophys Acta 1999; 1448: 512-518.
8. Martin WJ, MacIntyre DE. Melanocortin receptors and erectile function. Eur Urol 2004; 45: 706-713.
9. Starowicz K, Przewlocka B. The role of melanocortins and their receptors in inflammatory processes, nerve regeneration and nociception. Life Sci 2003; 73: 823-847.
10. Farooqi IS, Yeo GS, Keogh JM, Aminian S, Jebb SA, Butler G, Cheetham T, O'Rahilly S. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J Clin Invest 2006; 106: 271-279.
11. Bultman SJ, Michaud EJ, Woychik RP. Molecular characterization of the mouse agouti locus. Cell 1992; 71: 1195-1204.
12. Miller MW, Duhl DMJ, Vrieling H, Cordes SP, Ollmann MM, Winkes BM, Barsh GS. Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation. Genes Dev 1993; 7: 454-467.
13. Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RP, Wilkison WO, Cone RD. Agouti protein is an antagonist of the melanocyte-stimulating hormone receptor. Nature 1994; 371: 799-802.
14. Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 1997; 385: 165-168.
15. Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 1997; 88: 131-141.
16. Tachibana T, Sugahara K, Ohgushi A, Ando R, Kawakami S, Yoshimatsu T, Furuse M. Intracerebroventricular injection of agouti-related protein attenuates the anorexigenic effect of alpha-melanocyte stimulating hormone in neonatal chicks. Neurosci Lett 2001; 305: 131-134.
17. Cline MA, Smith ML. Central alpha-melanocyte stimulating hormone attenuates behavioural effects of neuropeptide Y in chicks. Physiol Behav 2007; 91: 588-592.
18. Abbott CR, Rossi M, Kim MS, Alahmed SH, Taylor GM, Ghatei MA, Smith DM, Bloom SR. Investigation of the melanocyte stimulating hormones on food intake. Lack of evidence to support a role for the melanocortin-3-receptor. Brain Res 2000; 869: 203-210.
19. Davis JL, Masuoka DT, Gerbandt LK, Cherkin A. Autoradiographic distribution of l-proline in chicks after intracerebroventricular injection. Physiol Behav 1979; 22: 693-695.
20. Anderson DK, Heisey SR. Clearance of molecules from cerebrospinal fluid in chickens. Am J Physiol 1972; 222: 645-648.
21. Kuenzel WJ, Masson M. A Stereotaxic Atlas of the Brain of the Chick (Gallus domesticus). Baltimore, MD: The Johns Hopkins University Press, 1988.
22. Kawakami S, Bungo T, Ando R, Ohgushi A, Shimojo M, Masuda Y, Furuse M. Central administration of alpha-melanocyte stimulating hormone inhibits fasting- and neuropeptide Y-induced feeding in neonatal chicks. Eur J Pharmacol 2000; 398: 361-364.
23. Schioth HB, Muceniece R, Larsson M, Mutulis F, Szardenings M, Prusis P, Lindeberg G, Wikberg JE. Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes. Eur J Pharmacol 1997; 319: 369-373.
24. Ling MK, Hotta E, Kilianova Z, Haitina T, Ringholm A, Johansson L, Gallo-Payet N, Takeuchi S, Schiöth HB. The melanocortin receptor subtypes in chicken have high preference to ACTH-derived peptides. Br J Pharmacol 2004; 143: 626-637.
25. Harrold JA, Widdowson PS, Williams G. β-MSH: A functional ligand that regulated energy homeostasis via hypothalamic MC4-R? Peptides 2003; 24: 397-405.
26. Harrold JA, Williams G. Melanocortin-4 receptors, β-MSH and leptin: key elements in the satiety pathway. Peptides 2006; 27: 365-371.
27. Brown KS, Gentry RM, Rowland NE. Central injection in rats of alpha-melanocyte-stimulating hormone analog: Effects on food intake and brain Fos. Regul Peptides 1998; 78: 89-94.
28. Holmberg SK, Mikko S, Boswell T, Zoorob R, Larhammar D. Pharmacological characterization of cloned chicken neuropeptide Y receptors Y1 and Y5. J Neurochem 2002; 81: 462-471.
29. Mountjoy KG, Mortund MT, Low MJ, Simerly RB, Cone RD. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 1994; 8: 1298-1308.
30. Bagnol D, Lu X, Kaelin CB, Day HEW, Ollmann M, Gantz I, Akil H, Barsh GS, Watson SJ. Anatomy of an endogenous antagonist: Relationship between agouti-related protein and proopiomelanocortin in the brain. J Neurosci 1999; 26: 1-7.
31. Lipositz Z, Paull WK. Association of dopaminergic fibers with corticotropin releasing hormone (CRH)-synthesizing neurons in the paraventricular nucleus of the rat hypothalamus. Histochemistry 1989; 93: 119-127.
32. Furuse M, Matsumoto M, Saito N, Sugahara K, Hasegawa S. The central corticotropin-releasing factor and glucagon-like peptide-1 in food intake of the neonatal chick. Eur J Pharmacol 1997; 339: 211-214.
33. Strader AD, Schioth HB, Buntin JD. The role of the melanocortin system and the melanocortin-4 receptor in ring dove (Streptopelia risoria) feeding behaviour. Brain Res 2003; 960: 112-121.
34. Brobeck JR. Mechanism of the development of obesity in animals with hypothalamic lesions. Physiol Rev 1946; 26: 541-559.
35. Anand BK, Brobeck JR. Hypothalamic control of food intake in rats and cats. Yale J Biol Med 1951; 24: 23-146.