PCBs and tight junction expression

Environmental Toxicology and Pharmacology

Volumn 25, Issue 2, 2008, Pages 234-240

  Eum, Sung Yong ^a   András, Ibolya E ^a   Couraud, Pierre Olivier ^c   Hennig, Bernhard ^b   Toborek, Michal ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c INSTITUT COCHIN   (France)

Author keywords

Blood brain barrier; Polychlorinated biphenyls; Tight junctions; Zonula occludens

Indexed keywords

CLAUDIN 1; JUNCTIONAL ADHESION MOLECULE A; MEMBRANE PROTEIN; POLYCHLORINATED BIPHENYL DERIVATIVE; PROTEIN ZO1; PROTEIN ZO2; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; TIGHT JUNCTION;

EID: 38549131276     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2007.10.019     Document Type: Article

References (58)

1. Abbott N.J. Dynamics of CNS barriers: evolution, differentiation, and modulation. Cell. Mol. Neurobiol. 25 (2005) 5-23
2. Alsharif N.Z., Lawson T., and Stohs S.J. Oxidative stress induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by the aryl hydrocarbon (Ah) receptor complex. Toxicology 92 (1994) 39-51
3. Andras I.E., Pu H., Deli M.A., Nath A., Hennig B., and Toborek M. HIV-1 tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells. J. Neurosci. Res. 74 (2003) 255-265
4. Balda M.S., and Matter K. The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression. EMBO J. 19 (2000) 2024-2033
5. Betanzos A., Huerta M., Lopez-Bayghen E., Azuara E., Amerena J., and Gonzalez-Mariscal L. The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells. Exp. Cell Res. 292 (2004) 51-66
6. Blum M.S., Toninelli E., Anderson J.M., Balda M.S., Zhou J., O'Donnell L., Pardi R., and Bender J.R. Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines. Am. J. Physiol. 273 (1997) H286-H294
7. Boettner B., Govek E.E., Cross J., and Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 9064-9069
8. Bolton S.J., Anthony D.C., and Perry V.H. Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo. Neuroscience 86 (1998) 1245-1257
9. Brown R.C., and Davis T.P. Calcium modulation of adherens and tight junction function: a potential mechanism for blood-brain barrier disruption after stroke. Stroke 33 (2002) 1706-1711
10. Carpenter D.O. Polychlorinated biphenyls (PCBs): routes of exposure and effects on human health. Rev. Environ. Health 21 (2006) 1-23
11. Chen M.L., Pothoulakis C., and LaMont J.T. Protein kinase C signaling regulates ZO-1 translocation and increased paracellular flux of T84 colonocytes exposed to clostridium difficile toxin A. J. Biol. Chem. 277 (2002) 4247-4254
12. Davies D.C. Blood-brain barrier breakdown in septic encephalopathy and brain tumours. J. Anat. 200 (2002) 639-646
13. Denker B.M., and Nigam S.K. Molecular structure and assembly of the tight junction. Am. J. Physiol. 274 (1998) F1-F9
14. Eum S.Y., Lee Y.W., Hennig B., and Toborek M. VEGF regulates PCB104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. Exp. Cell Res. 296 (2004) 231-244
15. Eum S.Y., Lee Y.W., Hennig B., and Toborek M. Interplay between epidermal growth factor receptor and janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells. Mol. Cancer Res. 4 (2006) 361-370
16. Fiala M., Liu Q.N., Sayre J., Pop V., Brahmandam V., Graves M.C., and Vinters H.V. Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier. Eur. J. Clin. Invest. 32 (2002) 360-371
17. Fischer S., Wiesnet M., Marti H.H., Renz D., and Schaper W. Simultaneous activation of several second messengers in hypoxia-induced hyperpermeability of brain derived endothelial cells. J. Cell Physiol. 198 (2004) 359-369
18. Groothuis D.R., Vriesendorp F.J., Kupfer B., Warnke P.C., Lapin G.D., Kuruvilla A., Vick N.A., Mikhael M.A., and Patlak C.S. Quantitative measurements of capillary transport in human brain tumors by computed tomography. Ann. Neurol. 30 (1991) 581-588
19. Hawkins B.T., and Davis T.P. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 57 (2005) 173-185
20. Hawkins B.T., Lundeen T.F., Norwood K.M., Brooks H.L., and Egleton R.D. Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases. Diabetologia 50 (2007) 202-211
21. Hennig B., Meerarani P., Slim R., Toborek M., Daugherty A., Silverstone A.E., and Robertson L.W. Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence. Toxicol. Appl. Pharmacol. 181 (2002) 174-183
22. Hollande F., Blanc E.M., Bali J.P., Whitehead R.H., Pelegrin A., Baldwin G.S., and Choquet A. HGF regulates tight junctions in new nontumorigenic gastric epithelial cell line. Am. J. Physiol. Gastrointest. Liver Physiol. 280 (2001) G910-G921
23. Hom S., Fleegal M.A., Egleton R.D., Campos C.R., Hawkins B.T., and Davis T.P. Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292 (2007) R1881-R1892
24. Jensen A.A. Background Levels in Humans, in Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxines and Related Products (1989), Elsevier Science Publishers
25. Jiang W.G., Martin T.A., Llaffafian I., and Mansel R.E. Tight junctions, a critical structure in the control of cancer invasion and metastasis. In: Jiang W.G., and Manse R.E. (Eds). Cancer Metastasis: Molecule and Cellular Mechanisms and Clinical Intervention (2000), Kluwer Academic, Amsterdam
26. Kanmogne G.D., Primeaux C., and Grammas P. HIV-1 gp120 proteins alter tight junction protein expression and brain endothelial cell permeability: implications for the pathogenesis of HIV-associated dementia. J. Neuropathol. Exp. Neurol. 64 (2005) 498-505
27. Knerr S., and Schrenk D. Carcinogenicity of "non-dioxinlike" polychlorinated biphenyls. Crit. Rev. Toxicol. 36 (2006) 663-694
28. Kustova Y., Grinberg A., and Basile A.S. Increased blood-brain barrier permeability in LP-BM5 infected mice is mediated by neuroexcitatory mechanisms. Brain Res. 839 (1999) 153-163
29. Lee D.W., and Opanashuk L.A. Polychlorinated biphenyl mixture Aroclor 1254-induced oxidative stress plays a role in dopaminergic cell injury. Neurotoxicology 25 (2004) 925-939
30. Liu D.Z., LeCluyse E.L., and Thakker D.R. Dodecylphosphocholine-mediated enhancement of paracellular permeability and cytotoxicity in Caco-2 cell monolayers. J. Pharm. Sci. 88 (1999) 1161-1168
31. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
32. Lohmann C., Krischke M., Wegener J., and Galla H.J. Tyrosine phosphatase inhibition induces loss of blood-brain barrier integrity by matrix metalloproteinase-dependent and -independent pathways. Brain Res. 995 (2004) 184-196
33. Lui W.Y., and Lee W.M. Camp perturbs inter-Sertoli tight junction permeability barrier in vitro via its effect on proteasome-sensitive ubiquitination of occludin. J. Cell. Physiol. 203 (2005) 564-572
34. Marco S., and Skaper S.D. Amyloid beta-peptide1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells. Neurosci. Lett. 401 (2006) 219-224
35. Morganti-Kossmann M.C., Rancan M., Stahel P.F., and Kossmann T. Inflammatory response in acute traumatic brain injury: a double-edged sword. Curr. Opin. Crit. Care 8 (2002) 101-105
36. Neuwelt E.A. Mechanisms of disease: the blood-brain barrier. Neurosurgery 54 (2004) 131-140 (discussion 141-132)
37. Norenberg M.D. Astrocyte responses to CNS injury. J. Neuropathol. Exp. Neurol. 53 (1994) 213-220
38. Pardridge W.M. Drug and gene delivery to the brain: the vascular route. Neuron 36 (2002) 555-558
39. Persidsky Y., Heilman D., Haorah J., Zelivyanskaya M., Persidsky R., Weber G.A., Shimokawa H., Kaibuchi K., and Ikezu T. Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). Blood 107 (2006) 4770-4780
40. Ryeom S.W., Paul D., and Goodenough D.A. Truncation mutants of the tight junction protein ZO-1 disrupt corneal epithelial cell morphology. Mol. Biol. Cell. 11 (2000) 1687-1696
41. Safe S., and Krishnan V. Cellular and molecular biology of aryl hydrocarbon (Ah) receptor-mediated gene expression. Arch. Toxicol. Suppl. 17 (1995) 99-115
42. Schlezinger J.J., Struntz W.D., Goldstone J.V., and Stegeman J.J. Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners. Aquat. Toxicol. 77 (2006) 422-432
43. Schlezinger J.J., White R.D., and Stegeman J.J. Oxidative inactivation of Cytochrome P-450 1A (CYP1A) stimulated by 3,3′,4,4′-Tetrachlorobiphenyl: production of reactive oxygen by vertebrate CYP1As. Mol. Pharmacol. 56 (1999) 588-597
44. Seegal R.F. The neurotoxicological consequences of developmental exposure to PCBs. Toxicol. Sci. 57 (2000) 1-3
45. Shibata S. Ultrastructure of capillary walls in human brain tumors. Acta Neuropathol. (Berl.) 78 (1989) 561-571
46. Stevenson B.R., Siliciano J.D., Mooseker M.S., and Goodenough D.A. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (Zonula Occludens) in a variety of epithelia. J. Cell. Biol. 103 (1986) 755-766
47. Thatcher T.H., Maggirwar S.B., Baglole C.J., Lakatos H.F., Gasiewicz T.A., Phipps R.P., and Sime P.J. Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappab component RelB. Am. J. Pathol. 170 (2007) 855-864
48. Toborek M., Barger S.W., Mattson M.P., Espandiari P., Robertson L.W., and Hennig B. Exposure to polychlorinated biphenyls causes endothelial cell dysfunction. J. Biochem. Toxicol. 10 (1995) 219-226
49. Traweger A., Fang D., Liu Y.C., Stelzhammer W., Krizbai I.A., Fresser F., Bauer H.C., and Bauer H. The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase Itch. J. Biol. Chem. 277 (2002) 10201-10208
50. Tsukita S., Furuse M., and Itoh M. Structural and signalling molecules come together at tight junctions. Curr. Opin. Cell Biol. 11 (1999) 628-633
51. Wassermann M., Wassermann D., Cucos S., and Miller H.J. World PCBs map: storage and effects in man and his biologic environment in the 1970s. Ann. N.Y. Acad. Sci. 320 (1979) 69-124
52. Weksler B.B., Subileau E.A., Perriere N., Charneau P., Holloway K., Leveque M., Tricoire-Leignel H., Nicotra A., Bourdoulous S., Turowski P., Male D.K., Roux F., Greenwood J., Romero I.A., and Couraud P.O. Blood-brain barrier-specific properties of a human adult brain endothelial cell line. FASEB J. 19 (2005) 1872-1874
53. Winneke G., Walkowiak J., and Lilienthal H. PCB-induced neurodevelopmental toxicity in human infants and its potential mediation by endocrine dysfunction. Toxicology 181-182 (2002) 161-165
54. Wolburg H., and Lippoldt A. Tight unctions of the blood-brain barrier: development, composition and regulation. Vascul. Pharmacol. 38 (2002) 323-337
55. Yamamoto T., Harada N., Kano K., Taya S., Canaani E., Matsuura Y., Mizoguchi A., Ide C., and Kaibuchi K. The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J. Cell Biol. 139 (1997) 785-795
56. Yang Y., Estrada E.Y., Thompson J.F., Liu W., and Rosenberg G.A. Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat. J. Cereb. Blood Flow Metab. 27 (2007) 697-709
57. Youakim A., and Ahdieh M. Interferon-gamma decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin. Am. J. Physiol. 276 (1999) G1279-G1288
58. Zhang Z., Rehmann H., Price L.S., Riedl J., and Bos J.L. AF6 negatively regulates Rap1-induced cell adhesion. J. Biol. Chem. 280 (2005) 33200-33205