메뉴 건너뛰기




Volumn 179, Issue 9, 2007, Pages 5958-5965

Anti-inflammatory properties and regulatory mechanism of a novel derivative of artemisinin in experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ARTEMISIN DERIVATIVE; CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; ETHYL 2 [4 (12 BETA ARTEMISININOXY)]PHENOXYLPROPIONATE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROTEIN JAB1; REGULATOR PROTEIN; RIG G PROTEIN; SM 933; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ARTEMISININ DERIVATIVE; AUTACOID; ETHYL 2 (4 (12 BETA ARTEMISININOXY))PHENOXYLPROPIONATE; ETHYL 2-(4-(12-BETA-ARTEMISININOXY))PHENOXYLPROPIONATE;

EID: 38449100734     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.9.5958     Document Type: Article
Times cited : (75)

References (35)
  • 1
    • 2142662186 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Hafler, D. A. 2004. Multiple sclerosis. J. Clin. Invest. 113: 788-794.
    • (2004) J. Clin. Invest , vol.113 , pp. 788-794
    • Hafler, D.A.1
  • 3
    • 20444482731 scopus 로고    scopus 로고
    • Pathogenesis of multiple sclerosis
    • Prat, A., and J. Antel. 2005. Pathogenesis of multiple sclerosis. Curr. Opin. Neurol. 18: 225-230.
    • (2005) Curr. Opin. Neurol , vol.18 , pp. 225-230
    • Prat, A.1    Antel, J.2
  • 6
    • 10944261736 scopus 로고    scopus 로고
    • Current approved options for treating patients with multiple sclerosis
    • Rizvi, S. A., and M. A. Agius. 2004. Current approved options for treating patients with multiple sclerosis. Neurology 63: S8-S14.
    • (2004) Neurology , vol.63
    • Rizvi, S.A.1    Agius, M.A.2
  • 7
    • 10944271463 scopus 로고    scopus 로고
    • Use of combination therapy with immunomodulators and immunosuppressants in treating multiple sclerosis
    • Jeffery, D. R. 2004. Use of combination therapy with immunomodulators and immunosuppressants in treating multiple sclerosis. Neurology 63: S41-S46.
    • (2004) Neurology , vol.63
    • Jeffery, D.R.1
  • 10
    • 33750943629 scopus 로고    scopus 로고
    • Neuroprotective effects of huperzine A: New therapeutic targets for neurodegenerative disease
    • Zhang, H. Y., and X. C. Tang. 2006. Neuroprotective effects of huperzine A: new therapeutic targets for neurodegenerative disease. Trends Pharmacol. Sci. 27: 619-625.
    • (2006) Trends Pharmacol. Sci , vol.27 , pp. 619-625
    • Zhang, H.Y.1    Tang, X.C.2
  • 11
    • 4344577124 scopus 로고    scopus 로고
    • Conquering the intolerable burden of malaria: What's new, what's needed: a summary
    • Breman, J. G., M. S. Alilio, and A. Mills. 2004. Conquering the intolerable burden of malaria: what's new, what's needed: a summary. Am. J. Trop. Med. Hyg. 71: 1-15.
    • (2004) Am. J. Trop. Med. Hyg , vol.71 , pp. 1-15
    • Breman, J.G.1    Alilio, M.S.2    Mills, A.3
  • 12
    • 2142659388 scopus 로고    scopus 로고
    • Antimalarial drug resistance
    • White, N. J. 2004. Antimalarial drug resistance. J. Clin. Invest. 113: 1084-1092.
    • (2004) J. Clin. Invest , vol.113 , pp. 1084-1092
    • White, N.J.1
  • 14
    • 59849100671 scopus 로고    scopus 로고
    • Pharmacology and toxicology of artemisinins
    • Zhang, J., and C. L. Yang. 2005. Pharmacology and toxicology of artemisinins. J. Hebei NU 22: 75-77.
    • (2005) J. Hebei NU , vol.22 , pp. 75-77
    • Zhang, J.1    Yang, C.L.2
  • 15
    • 22244471426 scopus 로고    scopus 로고
    • Synthesis and immunosuppressive activity of new artemisinin derivatives, 1: [12(β or α)- dihydroartemisininoxy] phen(ox)yl aliphatic acids and esters
    • Yang, Z. S., W. L. Zhou, Y. Sui, J. X. Wang, J. M. Wu, Y. Zhou, Y. Zhang, P. L. He, J. Y. Han, W. Tang, et al. 2005. Synthesis and immunosuppressive activity of new artemisinin derivatives, 1: [12(β or α)- dihydroartemisininoxy] phen(ox)yl aliphatic acids and esters. J. Med. Chem. 48: 4608-4617.
    • (2005) J. Med. Chem , vol.48 , pp. 4608-4617
    • Yang, Z.S.1    Zhou, W.L.2    Sui, Y.3    Wang, J.X.4    Wu, J.M.5    Zhou, Y.6    Zhang, Y.7    He, P.L.8    Han, J.Y.9    Tang, W.10
  • 16
    • 0035423415 scopus 로고    scopus 로고
    • Intrathecal delivery of IFN-γ protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes
    • Furlan, R., E. Brambilla, F. Ruffini, P. L. Poliani, A. Bergami, P. C. Marconi, D. M. Franciotta, G. Penna, G. Comi, L. Adorini, and G. Martino. 2001. Intrathecal delivery of IFN-γ protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes. J. Immunol. 167: 1821-1829.
    • (2001) J. Immunol , vol.167 , pp. 1821-1829
    • Furlan, R.1    Brambilla, E.2    Ruffini, F.3    Poliani, P.L.4    Bergami, A.5    Marconi, P.C.6    Franciotta, D.M.7    Penna, G.8    Comi, G.9    Adorini, L.10    Martino, G.11
  • 17
    • 0027448708 scopus 로고
    • MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination
    • Zhang, J., R. Medaer, P. Stinissen, D. Hafler, and J. Raus. 1993. MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination. Science 261: 1451-1454.
    • (1993) Science , vol.261 , pp. 1451-1454
    • Zhang, J.1    Medaer, R.2    Stinissen, P.3    Hafler, D.4    Raus, J.5
  • 18
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • Zhang, J., S. Markovic-Plese, B. Lacet, J. Raus, H. L. Weiner, and D. A. Hafler. 1994. Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J. Exp. Med. 179: 973-984.
    • (1994) J. Exp. Med , vol.179 , pp. 973-984
    • Zhang, J.1    Markovic-Plese, S.2    Lacet, B.3    Raus, J.4    Weiner, H.L.5    Hafler, D.A.6
  • 19
    • 23744465712 scopus 로고    scopus 로고
    • Trichosanthin inhibits antigen-specific T cell expansion through nitric oxide-mediated apoptosis pathway
    • Li, F., Y. Mei, Y. Wang, C. Chen, J. Tu, B. Xiao, and L. Xu. 2005. Trichosanthin inhibits antigen-specific T cell expansion through nitric oxide-mediated apoptosis pathway. Cell. Immunol. 234: 23-30.
    • (2005) Cell. Immunol , vol.234 , pp. 23-30
    • Li, F.1    Mei, Y.2    Wang, Y.3    Chen, C.4    Tu, J.5    Xiao, B.6    Xu, L.7
  • 21
    • 0033652765 scopus 로고    scopus 로고
    • Tumor necrosis factor α prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: Role of nuclear factor-κB
    • Nagaki, M., T. Naiki, D. A. Brenner, Y. Osawa, M. Imose, H. Hayashi, Y. Banno, S. Nakashima, and H. Moriwaki. 2000. Tumor necrosis factor α prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: role of nuclear factor-κB. Hepatology 32: 1272-1279.
    • (2000) Hepatology , vol.32 , pp. 1272-1279
    • Nagaki, M.1    Naiki, T.2    Brenner, D.A.3    Osawa, Y.4    Imose, M.5    Hayashi, H.6    Banno, Y.7    Nakashima, S.8    Moriwaki, H.9
  • 23
    • 0033198141 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in NF-κB-deficient mice: Roles of NF-κB in the activation and differentiation of autoreactive T cells
    • Hilliard, B., E. B. Samoilova, T. S. Liu, A. Rostami, and Y. Chen. 1999. Experimental autoimmune encephalomyelitis in NF-κB-deficient mice: roles of NF-κB in the activation and differentiation of autoreactive T cells. J. Immunol. 163: 2937-2943.
    • (1999) J. Immunol , vol.163 , pp. 2937-2943
    • Hilliard, B.1    Samoilova, E.B.2    Liu, T.S.3    Rostami, A.4    Chen, Y.5
  • 24
    • 0034746288 scopus 로고    scopus 로고
    • NF-κB in neuronal plasticity and neurodegenerative disorders
    • Mattson, M. P., and S. Camandola. 2001. NF-κB in neuronal plasticity and neurodegenerative disorders. J. Clin. Invest. 107: 247-254.
    • (2001) J. Clin. Invest , vol.107 , pp. 247-254
    • Mattson, M.P.1    Camandola, S.2
  • 25
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes, P. J., and M. Karin. 1997. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336: 1066-1071.
    • (1997) N. Engl. J. Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 27
    • 28544453229 scopus 로고    scopus 로고
    • Role of nuclear factor-κB in the immune system and bone
    • Jimi, E., and S. Ghosh. 2005. Role of nuclear factor-κB in the immune system and bone. Immunol. Rev. 208: 80-87.
    • (2005) Immunol. Rev , vol.208 , pp. 80-87
    • Jimi, E.1    Ghosh, S.2
  • 30
    • 33750843930 scopus 로고    scopus 로고
    • RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins
    • Xiao, S., D. Li, H. Q. Zhu, M. G. Song, X. R. Pan, P. M. Jia, L. L. Peng, A. X. Dou, G. Q. Chen, S. J. Chen, et al. 2006. RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteins. Proc. Natl. Acad. Sci. USA 103: 16448-16453.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16448-16453
    • Xiao, S.1    Li, D.2    Zhu, H.Q.3    Song, M.G.4    Pan, X.R.5    Jia, P.M.6    Peng, L.L.7    Dou, A.X.8    Chen, G.Q.9    Chen, S.J.10
  • 31
    • 33645324079 scopus 로고    scopus 로고
    • Drug insight: Interferon treatment in multiple sclerosis
    • Ann Marrie, R., and R. A. Rudick. 2006. Drug insight: interferon treatment in multiple sclerosis. Nat. Clin. Pract. Neurol. 2: 34-44.
    • (2006) Nat. Clin. Pract. Neurol , vol.2 , pp. 34-44
    • Ann Marrie, R.1    Rudick, R.A.2
  • 32
    • 23744480760 scopus 로고    scopus 로고
    • Glatiramer acetate in multiple sclerosis: Update on potential mechanisms of action
    • Farina, C., M. S. Weber, E. Meinl, H. Wekerle, and R. Hohlfeld. 2005. Glatiramer acetate in multiple sclerosis: update on potential mechanisms of action. Lancet Neurol. 4: 567-575.
    • (2005) Lancet Neurol , vol.4 , pp. 567-575
    • Farina, C.1    Weber, M.S.2    Meinl, E.3    Wekerle, H.4    Hohlfeld, R.5
  • 33
    • 0001112989 scopus 로고    scopus 로고
    • The antiinflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65
    • Lyss, G., A. Knorre, T. J. Schmidt, H. L. Pahl, and I. Merfort. 1998. The antiinflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-κB by directly targeting p65. J. Biol. Chem. 273: 33508-33516.
    • (1998) J. Biol. Chem , vol.273 , pp. 33508-33516
    • Lyss, G.1    Knorre, A.2    Schmidt, T.J.3    Pahl, H.L.4    Merfort, I.5
  • 34
    • 0035955729 scopus 로고    scopus 로고
    • Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones
    • Garcia-Pineres, A. J., V. Castro, G. Mora, J. Schmidt, E. Strunck, H. L. Pahl, and I. Merfort. 2001. Cysteine 38 in p65/NF-κB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J. Biol. Chem. 276: 39713-39720.
    • (2001) J. Biol. Chem , vol.276 , pp. 39713-39720
    • Garcia-Pineres, A.J.1    Castro, V.2    Mora, G.3    Schmidt, J.4    Strunck, E.5    Pahl, H.L.6    Merfort, I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.