메뉴 건너뛰기




Volumn 25, Issue 6, 2007, Pages 767-774

PKD1 inhibits cancer cells migration and invasion via Wnt signaling pathway in vitro

Author keywords

Cell migration; Invasion; PKD1 gene; Wnt signaling pathway

Indexed keywords

POLYCYSTIN 1; WNT PROTEIN; BETA CATENIN; CADHERIN; COMPLEMENTARY DNA; FRZB PROTEIN; GLYCOPROTEIN; POLYCYSTIC KIDNEY DISEASE 1 PROTEIN; POLYCYSTIN; UNCLASSIFIED DRUG; WNT1 PROTEIN;

EID: 38449094850     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1417     Document Type: Article
Times cited : (28)

References (33)
  • 1
    • 0030806513 scopus 로고    scopus 로고
    • Recent advances in the understanding of polycystic kidney disease
    • Bacallao RL, Carone FA. Recent advances in the understanding of polycystic kidney disease. Curr Opin Nephrol Hypertens 1997; 6: 377-383.
    • (1997) Curr Opin Nephrol Hypertens , vol.6 , pp. 377-383
    • Bacallao, R.L.1    Carone, F.A.2
  • 2
    • 0032949167 scopus 로고    scopus 로고
    • New insights into the molecular pathophysiology of polycystic kidney disease
    • Murcia NS, Sweeney WE, Jr, Avner ED. New insights into the molecular pathophysiology of polycystic kidney disease. Kidney Int 1999; 55: 1187-1197.
    • (1999) Kidney Int , vol.55 , pp. 1187-1197
    • Murcia, N.S.1    Sweeney Jr, W.E.2    Avner, E.D.3
  • 3
    • 2942534582 scopus 로고    scopus 로고
    • Polycystic kidney disease: New understanding in the pathogenesis
    • Wilson PD. Polycystic kidney disease: new understanding in the pathogenesis. Int J Biochem Cell Biol 2004; 36: 1868-1873.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1868-1873
    • Wilson, P.D.1
  • 4
    • 24644485135 scopus 로고    scopus 로고
    • Polycystins: Polymodal receptor/ion-channel cellular sensors
    • Delmas P. Polycystins: polymodal receptor/ion-channel cellular sensors. Pflugers Arch 2005; 451: 264-276.
    • (2005) Pflugers Arch , vol.451 , pp. 264-276
    • Delmas, P.1
  • 5
    • 0037133954 scopus 로고    scopus 로고
    • PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
    • Bhunia AK, Piontek K, Boletta A, et al. PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. Cell 2002; 109: 157-168.
    • (2002) Cell , vol.109 , pp. 157-168
    • Bhunia, A.K.1    Piontek, K.2    Boletta, A.3
  • 6
    • 0346740202 scopus 로고    scopus 로고
    • Cation channel regulation by COOH-terminal cytoplasmic tail of polycystin-1: Mutational and functional analysis
    • Vandorpe DH, Wilhelm S, Jiang L, et al. Cation channel regulation by COOH-terminal cytoplasmic tail of polycystin-1: mutational and functional analysis. Physiol Genomics 2002; 8: 87-98.
    • (2002) Physiol Genomics , vol.8 , pp. 87-98
    • Vandorpe, D.H.1    Wilhelm, S.2    Jiang, L.3
  • 7
    • 0033635231 scopus 로고    scopus 로고
    • Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells
    • Boletta A, Qian F, Onuchic LF, et al. Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells. Mol Cell 2000; 6: 1267-1273.
    • (2000) Mol Cell , vol.6 , pp. 1267-1273
    • Boletta, A.1    Qian, F.2    Onuchic, L.F.3
  • 8
    • 0035830869 scopus 로고    scopus 로고
    • The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel
    • Vandorpe DH, Chernova MN, Jiang L, et al. The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel. J Biol Chem 2001; 276: 4093-4101.
    • (2001) J Biol Chem , vol.276 , pp. 4093-4101
    • Vandorpe, D.H.1    Chernova, M.N.2    Jiang, L.3
  • 9
    • 0037205429 scopus 로고    scopus 로고
    • Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins
    • Parnell SC, Magenheimer BS, Maser RL, Zien CA, Frichant A-M, Calvet JP. Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins. J Biol Chem 2002; 277: 19566-19572.
    • (2002) J Biol Chem , vol.277 , pp. 19566-19572
    • Parnell, S.C.1    Magenheimer, B.S.2    Maser, R.L.3    Zien, C.A.4    Frichant, A.-M.5    Calvet, J.P.6
  • 10
    • 0033635231 scopus 로고    scopus 로고
    • Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells
    • Boletta A, Qian F, Onuchic LF, et al. Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells. Mol Cell 2000; 6: 1267-1273.
    • (2000) Mol Cell , vol.6 , pp. 1267-1273
    • Boletta, A.1    Qian, F.2    Onuchic, L.F.3
  • 11
    • 0142106807 scopus 로고    scopus 로고
    • Role of polycystins in renal tubulogenesis
    • Boletta A, Germino GG. Role of polycystins in renal tubulogenesis. Trends Cell Biol 2003; 13: 484-492.
    • (2003) Trends Cell Biol , vol.13 , pp. 484-492
    • Boletta, A.1    Germino, G.G.2
  • 12
    • 23744498205 scopus 로고    scopus 로고
    • Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation
    • Giuliani N, Colla S, Morandi F, et al. Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation. Blood 2005; 106: 2472-2483.
    • (2005) Blood , vol.106 , pp. 2472-2483
    • Giuliani, N.1    Colla, S.2    Morandi, F.3
  • 13
    • 0035079832 scopus 로고    scopus 로고
    • Polycystin: New aspects of structure, function, and regulation
    • Wilson PD. Polycystin: new aspects of structure, function, and regulation. J Am Soc Nephrol 2001; 12: 834-845.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 834-845
    • Wilson, P.D.1
  • 14
    • 0029069583 scopus 로고
    • The polycystic kidney disease 1(PKD1) gene encodes a novel protein with multiple cell recognition domains
    • Hughes J, Ward C, Peral B, et al. The polycystic kidney disease 1(PKD1) gene encodes a novel protein with multiple cell recognition domains. Nature Genet 1995; 10: 151-160.
    • (1995) Nature Genet , vol.10 , pp. 151-160
    • Hughes, J.1    Ward, C.2    Peral, B.3
  • 15
    • 0033555277 scopus 로고    scopus 로고
    • The structure of a PKD domain from polycystin-1: Implications for polycystic kidney disease
    • Bycroft M, Bateman A, Clarke J, et al. The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease. EMBO J 1999; 18: 297-305.
    • (1999) EMBO J , vol.18 , pp. 297-305
    • Bycroft, M.1    Bateman, A.2    Clarke, J.3
  • 16
    • 0032925372 scopus 로고    scopus 로고
    • Peptides from the PKD repeats of polycystin, the PKD1 gene product, modulate pattern formation in the developing kidney
    • Van AJ. Peptides from the PKD repeats of polycystin, the PKD1 gene product, modulate pattern formation in the developing kidney. Dev Genet 1999; 24: 299-308.
    • (1999) Dev Genet , vol.24 , pp. 299-308
    • Van, A.J.1
  • 17
    • 0034672628 scopus 로고    scopus 로고
    • Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation
    • Geng L, Burrow CR, Li HP, Wilson PD. Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation. Biochim Biophys Acta 2000; 1535: 21-35.
    • (2000) Biochim Biophys Acta , vol.1535 , pp. 21-35
    • Geng, L.1    Burrow, C.R.2    Li, H.P.3    Wilson, P.D.4
  • 18
    • 0032552866 scopus 로고    scopus 로고
    • The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro
    • Parnell SC, Magenheimer BS, Maser RL, et al. The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro. Biochem Biophys Res Commun 1998; 251: 625-631.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 625-631
    • Parnell, S.C.1    Magenheimer, B.S.2    Maser, R.L.3
  • 19
    • 0037192763 scopus 로고    scopus 로고
    • Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2
    • Delmas P, Nomura H, Li X, et al. Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2. J Biol Chem 2002; 277: 11276-11283.
    • (2002) J Biol Chem , vol.277 , pp. 11276-11283
    • Delmas, P.1    Nomura, H.2    Li, X.3
  • 20
  • 21
    • 0034214837 scopus 로고    scopus 로고
    • Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1
    • Ibraghimov-Beskrovnaya O, Bukanov NO, Donohue LC, Dackowski WR, Klinger KW, Landes GM. Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1. Hum Mol Genet 2000; 9: 1641-1649.
    • (2000) Hum Mol Genet , vol.9 , pp. 1641-1649
    • Ibraghimov-Beskrovnaya, O.1    Bukanov, N.O.2    Donohue, L.C.3    Dackowski, W.R.4    Klinger, K.W.5    Landes, G.M.6
  • 22
    • 0041561057 scopus 로고    scopus 로고
    • Cell adhesion system and human cancer morphogenesis
    • Hirohashi S, Kanai Y. Cell adhesion system and human cancer morphogenesis. Cancer Sci 2003; 94: 575-581.
    • (2003) Cancer Sci , vol.94 , pp. 575-581
    • Hirohashi, S.1    Kanai, Y.2
  • 23
    • 0035051814 scopus 로고    scopus 로고
    • E-cadherin immunostaining of bladder transitional cell carcinoma, carcinoma in situ and lymph node metastases with long-term followup
    • Byrne RR, Shariat SF, Brown R, et al. E-cadherin immunostaining of bladder transitional cell carcinoma, carcinoma in situ and lymph node metastases with long-term followup. J Urol 2001; 165: 1473-1479.
    • (2001) J Urol , vol.165 , pp. 1473-1479
    • Byrne, R.R.1    Shariat, S.F.2    Brown, R.3
  • 24
    • 0025765115 scopus 로고
    • E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells
    • Frixen UH, Behrens J, Sachs M, et al. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 1991; 113: 173-185.
    • (1991) J Cell Biol , vol.113 , pp. 173-185
    • Frixen, U.H.1    Behrens, J.2    Sachs, M.3
  • 25
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998; 392: 190-193.
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 26
    • 0032744937 scopus 로고    scopus 로고
    • Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins
    • Huan Y, Van AJ. Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins. J Clin Invest 1999; 104: 1459-1468.
    • (1999) J Clin Invest , vol.104 , pp. 1459-1468
    • Huan, Y.1    Van, A.J.2
  • 27
    • 0033574983 scopus 로고    scopus 로고
    • Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain
    • Parnell SC, Magenheimer BS, Maser RL, Calvet JP. Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain. Biochem Biophys Res Commun 1999; 259: 539-543.
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 539-543
    • Parnell, S.C.1    Magenheimer, B.S.2    Maser, R.L.3    Calvet, J.P.4
  • 28
    • 0033582438 scopus 로고    scopus 로고
    • The polycystic kidney disease 1 gene product modulates Wnt signaling
    • Kim E, Arnould T, Sellin LK, et al. The polycystic kidney disease 1 gene product modulates Wnt signaling. J Biol Chem 1999; 274: 4947-4953.
    • (1999) J Biol Chem , vol.274 , pp. 4947-4953
    • Kim, E.1    Arnould, T.2    Sellin, L.K.3
  • 29
    • 33644800948 scopus 로고    scopus 로고
    • Increased activity of activator protein-1 transcription factor components ATF2, c-Jun, and c-Fos in human and mouse autosomal dominant polycystic kidney disease
    • Le NH, Van der WA, Van der BP, et al. Increased activity of activator protein-1 transcription factor components ATF2, c-Jun, and c-Fos in human and mouse autosomal dominant polycystic kidney disease. J Am Soc Nephrol 2005; 16: 2724-2731.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2724-2731
    • Le NH, V.D.W.1    Van der, B.P.2
  • 30
    • 33748748479 scopus 로고    scopus 로고
    • The polycystin 1-C-terminal fragment stimulates ERK-dependenl spreading of renal epithelial cells
    • Joly D, Ishibe S, Nickel C, Yu Z, Somlo S, Cantley LG. The polycystin 1-C-terminal fragment stimulates ERK-dependenl spreading of renal epithelial cells. J Biol Chem 2006; 281: 26329-26339.
    • (2006) J Biol Chem , vol.281 , pp. 26329-26339
    • Joly, D.1    Ishibe, S.2    Nickel, C.3    Yu, Z.4    Somlo, S.5    Cantley, L.G.6
  • 31
    • 16844375093 scopus 로고    scopus 로고
    • PKD1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation
    • Nishio S, Hatano M, Nagata M, et al. PKD1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest 2005; 115: 910-918.
    • (2005) J Clin Invest , vol.115 , pp. 910-918
    • Nishio, S.1    Hatano, M.2    Nagata, M.3
  • 32
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and Cadherin pathways
    • Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and Cadherin pathways. Science 2004; 303: 1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 33
    • 0028305138 scopus 로고
    • Dynamics of cadherin/catenin complex formation: Novel protein interactions and pathways of complex assembly
    • Hinck L, Nathke IS, Papkoff J, Nelson WJ. Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J Cell Biol 1994; 125: 1327-1340.
    • (1994) J Cell Biol , vol.125 , pp. 1327-1340
    • Hinck, L.1    Nathke, I.S.2    Papkoff, J.3    Nelson, W.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.