Effects of some 1,4-dihydropyridine Ca antagonists on the blast transformation of rat spleen lymphocytes

Cell Biochemistry and Function

Volumn 17, Issue 2, 1999, Pages 97-105

  Briede, Janina ^a   Daija, Daina ^a   Bisenieks, Egils ^a   Makarova, Natalija ^a   Uldriķis, Janis ^a   Poikans, Janis ^a   Duburs, Gunars ^a  

^a LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

Author keywords

1,4 Dihydropyridine; Blast transformation; Ca antagonists; Cerebrocrast; Etaftoron; Nicardipine; Nifedipine; Niludipine; Nimodipine; Rat spleen lymphocytes

Indexed keywords

CALCIUM ANTAGONIST; CALCIUM ION; CELL SURFACE RECEPTOR; CEREBROCRAST; CONCANAVALIN A; CYCLIC AMP; INSULIN; INSULIN ANTIBODY; INTERLEUKIN 2; LYMPHOCYTE RECEPTOR; NICARDIPINE; NIFEDIPINE; NILUDIPINE; NIMODIPINE; PHOSPHODIESTERASE; RECOMBINANT INTERLEUKIN 2;

ANIMAL CELL; ARTICLE; BLAST TRANSFORMATION; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL STIMULATION; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DNA SYNTHESIS; ENZYME ACTIVITY; HELPER CELL; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SPLEEN LYMPHOCYTE; SUPPRESSOR CELL;

ANIMALS; CALCIUM CHANNEL BLOCKERS; DIHYDROPYRIDINES; LYMPHOCYTE ACTIVATION; NICARDIPINE; NIFEDIPINE; NIMODIPINE; RATS; SPLEEN;

ANIMALIA;

EID: 0033034752     PISSN: 02636484     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0844(199906)17:2<97::AID-CBF814>3.0.CO;2-4     Document Type: Article

References (52)

1. Cheung, R. K., Grinstein, S. and Gelfand, E. W. (1983). Permissive role of calcium in the inhibition of T cell mitogenesis by calmodulin antagonists. J. Immunol., 131, 2291.
2. 3 receptor: localization to plasma-membrane of T cells and cocapping with the T cell receptor. Science, 257, 5071, 815-818.
3. Berridge, M. J. (1993). Inositol trisphosphate and calcium signalling. Nature, 361, 315-325.
4. 2+ and membrane potential in lymphocytes. Nature, 295, 5844, 68-71.
5. Kuno, M. and Gardner, Ph. (1987). Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes. Nature, 326, 301-304.
6. Neher, E. (1987). Receptor-operated Ca channels. Nature, 326, 242.
7. 2+ and glucose on multiplication and functional differentiation of clonal insulin-producing cells (RIN m 5F). Diabetologia, 27, 256.
8. Lewis, R. S. and Cahalan, M. D. (1995). Potassium and calcium channels in lymphocytes. Ann. Rev. Immunol., 13, 623-653.
9. 2+-dependent period during mitogenic stimulation, Immunology, 28, 121-125.
10. Diamantstein, T. and Ulmer, A. (1975). The antagonistic action of cyclic GMP and cyclic AMP on proliferation of B and T lymphocytes. Immunology, 28, 113-119.
11. Smith, J. W., Steiner, A. L. and Parker, C. (1971). Human lymphocyte metabolism effects of cyclic and noncyclic nucleotides on stimulation by phytohaemagglutinin. J. Clin. Invest., 50, 442-448.
12. Egorin, M. J., Felsted, R. L. and Bachur, N. R. (1977). Phytohaemagglutinin isolectin stimulation of glucose utilisation by lymphocytes. Life Sci., 20(2), 351-358.
13. Birx, D. L., Berger, M. and Fleisher, Th. A. (1984). The interference of T cell activation by calcium channel blocking agents. J. Immunol., 133(6), 2904-2909.
14. Gardner, Ph. (1989). Calcium and T lymphocyte activation. Cell, 59(1), 15-20.
15. Hemar, A. A., Subtil, A., Lieb, M., Morelon, E. and Hellio, R. (1995). Endocytosis of interleukin-2 receptors in human T-lymphocytes distinct intracellular localisation and fate of the receptor α, β and γ chains. J. Cell Biol., 129(1), 55-64.
16. Blitstein-Willinger, E. and Diamantstein, T. (1978). Inhibition by isoptin (a calcium antagonists) of the mitogenic stimulation of lymphocytes prior to the S-phase. Immunology, 34(2), 303-307.
17. 2+ antagonists. J. Cell Physiol., 124, 131-136.
18. Hess, P., Lasman, J. B. and Tsien, R. W. (1984). Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature, 311, 538-544.
19. Himori, N., Ono, H. and Taira, N. (1976). Simultaneous assessment of effects of coronary vasodilatators on the coronary blood flow and the myocardial contractility by using the blood-perfused cavine papillary muscles. Japan J. Pharmacol., 26, 427-435.
20. Veniant, M., Clozel, J. P., Hess, P. and Wolfgang, R. (1991). Hemodynamic profile of RO40-5967 in conscious rats: comparison with diltiazem, verapamil and amlodipine. J. Cardiov. Pharm., 18(Suppl. 10), 55-58.
21. Leech, C. A., Holz, G. G. IV and Habener, J. F. (1994). Voltage-independent calcium channels mediate slow oscillation of cytosolic calcium that are glucose dependent in pancreatic β-cells. Endocrinology, 135(1), 365-372.
22. Webb, D. R., Kraig, E. and Devens, B. H. (1994). Suppressor cells and immunity. In: Mechanism of Immune Regulation. (Grandstein, R. D., ed.). Karger: Basel, pp. 146-192.
23. 8 cells in type 1 (insulin-dependent) diabetes. Diabetologia, 27, 276.
24. Sinclair, T. F., Singh, S. P., Ellyin, F., Kilger, K. and Ezdenli, E. Z. (1983). T-helper to T-suppressor lymphocyte absolute numbers in diabetes mellitus. Diabetes, 32(Suppl. 1), 23.
25. Dupre, I. and Stiller, C. R. (1988). Induction of partial remission and enhancement of Beta-cell function by cyclosporin in type I diabetes. In: Diabetes Mellitus Pathophysiology and Therapy. (Creutzfeldt, W. and Lefebvre, P., eds). pp. 321-335.
26. Belevics, G. V., Dubur, G. J., Spirin, M. M. and Dobretcov, G. E. (1986). Localisation of calcium antagonist riodipine in cell membrane fluorescence studies. Biol. Membr., 3, 368-375.
27. Makarova, N. V., Belevics, G. V., Bisenieks, E. A., Veveris, M. M. and Dubur, G. J. (1988). Synthesis, biological activity and affinity to model phospholipid membranes of alkyl- and cyclo-alkyl derivatives of 1.4-dihydropyridine-3.5-dicarboxylic acid. Khim.-Farm. Zh., 7. 810-816.
28. Bossert, F. and Vater, W. (1971). Dihydropyridine, eine neue Gruppe stark wirksamer Coronartherapeulica. Naturwissenschaften, 58, 11, 578.
29. Bossert, F., Horstmann, H., Meyer, H. and Vater, W. (1979). Einfluß der Esterfunktion auf die vasodilatierenden Eigenschaften von 1,4-Dihydro-2.6-dimethyl-4-nitrophenyl-pyridin-3,5-dicarbon-saureestern. Arzneim. Forch./Drug Res., 29(1), 226-229.
30. Meyer, H., Bossert, F., Vater, W. and Stoepel, K. (1972). Dialkyl 4-acyl-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylates. Ger. Pat. 2117571, (Chem. Abstr., 1973, 78(3), 16038).
31. Iwanami, M., Shibanuma, T., Fujimoto, M., Kalvai, R., Tamazawa, K., Takenaka, T., Takahashi, K. and Murakami, M. (1979). Synthesis of new water soluble dihydropyridine vasodilators. Chem. Pharm. Bull., 27(6), 1426-1440.
32. Dubur, G. J., Veveris, M. M., Weinheimer, G., Bisenieks, E. A., Makarova, V. R., Dimenis, A. A., Uldrikis, J. R., Lukevics, L. J., Dooley, D. and Osswald, H. (1989). Synthesis and selective vasodilating properties of esters of 2,6-dimethyl-4-(2-difluoromethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid. Arzneim. Forsch./Drug Res., 39(10)(11), 1185-1189.
33. Parinov, V. J., Odinec, A. G., Gilev, A. P., Dubur, G. J., Muceniece, D. H., Ozol, J., Shatz, V. D., Gavars, M. P. and Vigante, B. A. (1985). Pharmacokinetics and metabolism of ryodipine in rats. Arzeim.-Forsch./Drug Res., 35(5)(1) 808-813.
34. Cambier, J. C., Pleiman, C. M. and Clark, M. R. (1994). Signal transduction by the B cell antigen receptor and its coreceptors. Ann. Rev. Immunol., 12, 457-486.
35. Fu, L. X., Waagstein, F. and Hjalmarson, A. (1991). G proteins and calcium channels in myocardium. Life Sci., 48, 2291-2295.
36. Akha, A. A., Willmot, N. J., Brickley, K., Dolphin, A. C., Galione, A. and Hunt, S. V. (1996). Anti-lg-induced calcium influx in rat B lymphocytes mediated by cGMP through a dihydropyridine-sensitive channel. J. Biol. Chem., 271(13), 7297-7300.
37. 1 protein. J. Biol. Chem., 272, 14733-14739.
38. van Tits, L. J. H. and Brodde, O. E. (1990). Cyclic AMP antagonizes mitogen-induced accumulation of inositol phosphates in human peripheral mononuclear leucocytes (MNL) in vitro. Archiv. Pharmacol., 341(Suppl.), R. 82.
39. Novak, Th. J and Rothenberg, E. V. (1990). cAMP inhibits induction of interleukin 2 but not of inlerleukin 4. Proc. Natl. Acad. Sci. U.S.A., 87, 9353-9357.
40. 2+ transport and cAMP accumulation in the rabbit-isolated myocardium strip. Exptl. Clin. Pharmacother., 14, 98-102 (in Russian).
41. Krug, U., Krug, F. and Cuatrecasas, P. (1972). Emergence of insulin receptors in human lymphocytes during in vitro transformation. Proc. Natl. Acad. Sci. U.S.A., 69(9), 2604-2608.
42. Cuatrecasas, P. and Tell, G. P. E. (1973). Insulin-like activity by concanavalin A and wheatgerm agglutinin-direct interactions with insulin receptors. Proc. Natl. Acad. Sci. U.S.A., 70(2), 485-489.
43. Baldwin, D. Jr., Terris, S. and Steiner, D. F. (1980). Characterization of insulin-like actions of anti-insulin receptor antibodies. J. Biol. Chem., 255(9), 4028-4034.
44. Kahn, C. R., Baird, K. L., Jarrett, D. B. and Flier, J. S. (1978). Direct demonstration that receptor crosslinking or aggregation is important in insulin action. Proc. Natl. Acad. Sci. U.S.A., 75(9), 4209-4213.
45. Flier, J. S., Kahn, C. R., Jarrett, D. B. and Roth, J. (1976). Characterization of antibodies to the insulin receptor. J. Clin. Invest., 58(6), 1442-1449.
46. Flier, J. S., Kahn, C. R., Roth, J. and Bar, R. S. (1975). Antibodies that impair insulin receptor binding in an unusual diabetic syndrome with severe insulin resistance. Science, 190, 63-65.
47. Choquet, D., Partiseti. M., Amigorena, S., Bonnerot, Ch. and Fridman, W. H. (1993). Cross-linking of IgG receptors inhibits membrane immunoglobulin-stimulated calcium influx in B lymphocytes. J. Immunol., 121(2), 355-363.
48. Rhodes, J. (1975). Modulation of macrophage Fc receptor expression in vitro by insulin and cyclic nucleotides. Nature, 257, 597-599.
49. Mantovani, B., Rabinovitch, M. and Nussenzweig, V. (1972). Phagocytosis of immune complex by macrophages. Different roles of the macrophage receptor sites for complement (C3) and for immunoglobulin (IgG). J. Exp. Med., 135, 780.
50. Abrass, C. K. and Hori, M. (1984). Alteraction in Fc receptor functions of macrophages from streptozotocin-induced diabetic rats. J. Immunol., 133, 1307.
51. Bar, R. S., Kahn, C. R. and Koren, H. S. (1977). Insulin inhibition of antibody-dependent cytotoxicity and insulin receptors in macrophages. Nature, 265, 632-635.
52. Scott, J., Engelhard, V. N. and Benjamin, D. C. (1984). Enhancement of mixed lymphocyte responses (MLR) and mitogen stimulation in BB rat lymphocytes by IL-2. Diabetes, 33(Suppl. I), 61.