Reversal of P-glycoprotein-mediated multidrug resistance by Alisol B 23-acetate

Biochemical Pharmacology

Volumn 68, Issue 5, 2004, Pages 843-855

  Wang, Cheng ^a   Zhang, Jin Xia ^a   Shen, Xiao Ling ^a   Wan, Chi Keung ^a   Tse, Anfernee Kai Wing ^a   Fong, Wang Fun ^a  

^a CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

ABA; Alisol B 23 aceatate; Alisol B 23 acetate; Chemosensitizer; CI; combination index; MDR; multidrug resistance; Multidrug resistance; P glycoprotein; P gp; Rh 123; rhodamine 123; 125I iodoarylazidoprazosin; 125I IAAP

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALISOL B 23 ACETATE; CISPLATIN; DACTINOMYCIN; DOXORUBICIN; FLUOROURACIL; GLYCOPROTEIN P; IODINE 125; PACLITAXEL; PLANT EXTRACT; PUROMYCIN; RHIZOMA ALISMATIS EXTRACT; RHODAMINE 123; UNCLASSIFIED DRUG; VERAPAMIL; VINBLASTINE;

ARTICLE; BIOASSAY; CANCER CELL; CELL CYCLE G2 PHASE; CELL LINE; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SENSITIVITY; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MULTIDRUG RESISTANCE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHIZOMA ALISMATIS;

EID: 3843091577     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.05.021     Document Type: Article

References (30)

1. Kartner N., Riordan J.R., Ling V. Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science. 221:1983;1285-1288
2. Germann U.A. P-glycoprotein - a mediator of multidrug resistance in tumour cells. Eur. J. Cancer. 32:1996;927-944
3. Tsuruo T., Iida H., Nojiri M., Tsukagoshi S., Sakural Y. Circumvention of vincristine and adriamycin resistance in vitro and in vivo by calcium influx blockers. Cancer Res. 43:1983;2905-2910
4. Kiue A., Sano T., Naito A., Okumura M., Kohno K., Kuwano M. Enhancement of antitumour activity of etoposide by dihydropyridines on drug-sensitive and drug-resistant leukemia in mice. Br. J. Cancer. 64:1991;221-226
5. Hyafil F., Vergely C., Vignaud P.D., Grand-Perret T. In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative. Cancer Res. 53:1993;4595-4602
6. Ford J.M., Hait W.N. Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol. Rev. 42:1990;155-199
7. Pennock G.D., Dalton W.S., Roeske W.R., Appleton C.P., Mosley K., Plezia P., et al. Systemic toxic effects associated with high-dose verapamil infusion and chemotherapy administration. J. Natl. Cancer Inst. 83:1991;105-110
8. Chan J.Y., Chu A.C., Fung K.P. Inhibition of P-glycoprotein expression and reversal of drug resistance of human hepatoma HepG2 cells by multidrug resistance gene (mdr1) antisense RNA. Life Sci. 67:2000;2117-2124
9. Skehan P., Storeng R., Scudiero D., Monks A., McMahon J., Vistica D., et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 82:1990;1107-1112
10. Chou TC, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. In: Weber G, editor. Advances in enzyme regulation, vol. 22. Oxford: Pergamon Press; 1984. p. 27-55.
11. Lam W., Chan H., Yang M.S., Cheng S., Fong W.F. Synergism of energy starvation and dextran-conjugated doxorubicin in the killing of multidrug-resistant KB carcinoma cells. Anticancer Drugs. 10:1999;171-178
12. Chou T.C., Talalay P. Analysis of combined drug effects: a new look at a very old problem. Trends Pharmacol. Sci. 4:1983;450-454
13. DiDiodato G., Sharom F.J. Interaction of combinations of drugs, chemosensitizers, and peptides with the P-glycoprotein multidrug transporter. Biochem. Pharmacol. 53:1997;1789-1797
14. Ludescher C., Thaler J., Drach J., Spitale M., Gattringer C., Huber H., et al. Detection of activity of P-glycoproteinn in human tumor samples using rhodamine 123. Br. J. Haematol. 2:1992;161-168
15. Krishan A., Ganapathi R. Laser flow cytometry and cancer chemotherapy: detection of intracellular antharcyclines by flow cytometry. J. Histochem. Cytochem. 27:1979;1655-1666
16. Cornwell M.M., Gottesman M.M., Pastan I.H. Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells. J. Biol. Chem. 261:1986;7921-7928
17. Safa A.R. Photo-affinity labeling of the multidrug-resistance-related P-glycoprotein with photo-active analogs of verapamil. Proc. Natl. Acad. Sci. USA. 85:1988;7187-7191
18. Wang E.J., Casciano C.N., Clement R.P., Johnson W.W. Two transport binding site of P-glycoprotein are unequal yet contingent: initial rate kinetic analysis by ATP hydrolysis demonstrates intersite dependence. Biochim. Biophys. Acta. 1481:2000;63-74
19. Peng GP, Lou FC. Terpenoids of Alisma orientalis Juzep. Nat Prod Res Dev 2001;13(4):1-4.
20. 1. Cancer Res. 60(22):2000;6403-6407
21. Ramachandra M., Ambudkar S.V., Chen D., Hrycyna C.A., Dey S., Gottesman M.M., et al. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. Biochemistry. 37:1998;5010-5019
22. Nooter K., Stoter G. Molecular mechanisms of multidrug resistance in cancer chemotherapy. Pathol. Res. Pract. 192(7):1996;768-780
23. Chen H.W., Hsu M.J., Chien C.T., Huang H.C. Effect of alisol B acetate, a plant triterpene, on apoptosis in vascular smooth muscle cells and lymphocytes. Eur. J. Pharmacol. 419(2/3):2001;127-138
24. Lee S., Kho Y., Min B., Kim J., Na M., Kang S., et al. Cytotoxic triterpenoides from Alismatis Rhizoma. Arch Pharm. Res. 24(6):2001;524-526
25. Pascaud C., Garrigos M., Orlowski S. Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents. Biochem. J. 333(Pt. 2):1998;351-358
26. Litman T., Zeuthen T., Skovsgaard T., Stein W.D. Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity. Biochim. Biophys. Acta. 1361(2):1997;169-176
27. Isenberg B., Thole H., Tummler B., Demmer A. Identification and localization of three photobinding sites of iodoarylazidoprazosin in hamster P-glycoprotein. Eur. J. Biochem. 268(9):2001;2629-2634
28. Klopman G., Shi L.M., Ramu A. Quantitative structure-activity relationship of multidrug resistance reversal agents. Mol. Pharmacol. 52:1997;323-334
29. Zamora J.M., Pearce H.L., Beck W.T. Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells. Mol. Pharmacol. 33:1988;454-462
30. Hu Y.P., Pourquier P., Doignon F., Crouzet M., Robert J. Effects of modulators of multidrug resistance on the expression of the MDR1 gene in human KB cells in culture. Anticancer Drugs. 7:1996;738-744