메뉴 건너뛰기




Volumn 82, Issue 3, 2004, Pages 351-359

Protective role of heme oxygenase in the blood vessel wall during atherogenesis

Author keywords

Antioxidant enzymes; Atherosclerosis; Gene therapy; Heme oxygenase; Oxidized LDL

Indexed keywords

ANTIOXIDANTS; BLOOD VESSELS; CARBON MONOXIDE; CATALYSIS; GENES; IRON; OXYGENATORS;

EID: 3843090635     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o04-006     Document Type: Short Survey
Times cited : (46)

References (108)
  • 2
    • 0031756221 scopus 로고    scopus 로고
    • Linoleyl hydroperoxide transcriptionally upregulates heme oxygenase-1 gene expression in human renal epithelial and aortic endothelial cells
    • Agarwal, A., Shiraishi, F., Visner, G.A., and Nick, H.S. 1998. Linoleyl hydroperoxide transcriptionally upregulates heme oxygenase-1 gene expression in human renal epithelial and aortic endothelial cells. J. Am. Soc. Nephr. 9: 1990-1997.
    • (1998) J. Am. Soc. Nephr. , vol.9 , pp. 1990-1997
    • Agarwal, A.1    Shiraishi, F.2    Visner, G.A.3    Nick, H.S.4
  • 3
    • 0026788471 scopus 로고
    • Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene
    • Alam, J., and Den, Z. 1992. Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene. J. Biol. Chem. 267: 21 894-21 900.
    • (1992) J. Biol. Chem. , vol.267 , pp. 21894-21900
    • Alam, J.1    Den, Z.2
  • 4
    • 0033452790 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury
    • Amersi, F., Buelow, R., Kato, H., Ke, B., Coito, A.J., et al. 1999. Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. J. Clin. Investig. 104: 1631-1639.
    • (1999) J. Clin. Investig. , vol.104 , pp. 1631-1639
    • Amersi, F.1    Buelow, R.2    Kato, H.3    Ke, B.4    Coito, A.J.5
  • 5
    • 0027739703 scopus 로고
    • Bilirubin inhibits protein kinase C activity and protein kinase C-mediated phosphorylation of endogenous substrates in human skin fibroblasts
    • Amit, Y., and Boneh, A. 1993. Bilirubin inhibits protein kinase C activity and protein kinase C-mediated phosphorylation of endogenous substrates in human skin fibroblasts. Clin. Chim. Acta 223: 103-111.
    • (1993) Clin. Chim. Acta , vol.223 , pp. 103-111
    • Amit, Y.1    Boneh, A.2
  • 6
    • 0034525341 scopus 로고    scopus 로고
    • Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases
    • Aviram, M. 2000. Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases. Free Radic. Res. 33: S85-S97.
    • (2000) Free Radic. Res. , vol.33
    • Aviram, M.1
  • 8
    • 0027358877 scopus 로고
    • Endothelial-cell heme uptake from heme proteins: Induction of sensitization and desensitization to oxidant damage
    • Balla, J., Jacob, H.S., Balla, G., Nath, K.A., Eaton, J.W., and Vercellotti, G.M. 1993. Endothelial-cell heme uptake from heme proteins: Induction of sensitization and desensitization to oxidant damage. Proc. Natl. Acad. Sci. U.S.A. 90: 9285-9289.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 9285-9289
    • Balla, J.1    Jacob, H.S.2    Balla, G.3    Nath, K.A.4    Eaton, J.W.5    Vercellotti, G.M.6
  • 9
    • 0029883764 scopus 로고    scopus 로고
    • The role of oxidized lipoproteins in atherogenesis
    • Berliner, J.A., and Heinecke, J.W. 1996. The role of oxidized lipoproteins in atherogenesis. Free Radic. Biol. Med. 20: 707-727.
    • (1996) Free Radic. Biol. Med. , vol.20 , pp. 707-727
    • Berliner, J.A.1    Heinecke, J.W.2
  • 10
    • 0020972414 scopus 로고
    • Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atherosclerosis
    • Brown, M.S., and Goldstein, J.L. 1983. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Ann. Rev. Biochem. 52: 223-261.
    • (1983) Ann. Rev. Biochem. , vol.52 , pp. 223-261
    • Brown, M.S.1    Goldstein, J.L.2
  • 11
    • 0019297268 scopus 로고
    • The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages
    • Brown, M.S., Basu, S.K., Falck, J.R., Ho, Y.K., and Goldstein, J.L. 1980. The scavenger cell pathway for lipoprotein degradation: specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages. J. Supramol. Struct. 13: 67-81.
    • (1980) J. Supramol. Struct. , vol.13 , pp. 67-81
    • Brown, M.S.1    Basu, S.K.2    Falck, J.R.3    Ho, Y.K.4    Goldstein, J.L.5
  • 12
    • 0034721576 scopus 로고    scopus 로고
    • Differential regulation of H- and L-ferritin messenger RNA sub-units, ferritin protein and iron following focal cerebral ischemia-reperfusion
    • Chi, S.I., Wang, C.K., Chen, J.J., Chau, L.Y., Lin, T.N. 2000. Differential regulation of H- and L-ferritin messenger RNA sub-units, ferritin protein and iron following focal cerebral ischemia-reperfusion. Neuroscience, 100: 475-484.
    • (2000) Neuroscience , vol.100 , pp. 475-484
    • Chi, S.I.1    Wang, C.K.2    Chen, J.J.3    Chau, L.Y.4    Lin, T.N.5
  • 13
    • 0028593507 scopus 로고
    • Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements
    • Dalton, T., Palmiter, R.D., and Andrews, G.K. 1994. Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res. 22: 5016-5023.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5016-5023
    • Dalton, T.1    Palmiter, R.D.2    Andrews, G.K.3
  • 14
    • 0036080373 scopus 로고    scopus 로고
    • Mouse models of atherosclerosis
    • Daugherty, A. 2002. Mouse models of atherosclerosis. Am. J. Med. Sci. 323: 3-10.
    • (2002) Am. J. Med. Sci. , vol.323 , pp. 3-10
    • Daugherty, A.1
  • 16
    • 0030961521 scopus 로고    scopus 로고
    • Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells
    • Durante, W., Kroll, M.H., Christodoulides, N., Peyton, K.J., and Schafer, A.I. 1997. Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ. Res. 80: 557-564.
    • (1997) Circ. Res. , vol.80 , pp. 557-564
    • Durante, W.1    Kroll, M.H.2    Christodoulides, N.3    Peyton, K.J.4    Schafer, A.I.5
  • 17
    • 0035852471 scopus 로고    scopus 로고
    • Low-dose aspirin and vitamin E in people at cardiovascular risk: A randomised trial in general practice
    • Collaborative Group of the Primary Prevention Project
    • de Gaetano, G., and Collaborative Group of the Primary Prevention Project. 2001. Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Collaborative Group of the Primary Prevention Project. Lancet, 357: 89-95.
    • (2001) Lancet , vol.357 , pp. 89-95
    • De Gaetano, G.1
  • 18
    • 0034760290 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with restenosis after percutaneous transluminal angioplasty
    • Exner, M., Schillinger, M., Minar, E., Mlekusch, W., Schlerka, G., Haumer, M., Mannhalter, C., and Wagner, O. et al. 2001. Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with restenosis after percutaneous transluminal angioplasty. J. Endovasc. Ther. 8: 433-440.
    • (2001) J. Endovasc. Ther. , vol.8 , pp. 433-440
    • Exner, M.1    Schillinger, M.2    Minar, E.3    Mlekusch, W.4    Schlerka, G.5    Haumer, M.6    Mannhalter, C.7    Wagner, O.8
  • 20
    • 0033113291 scopus 로고    scopus 로고
    • Iron regulates hyperoxia-dependent human heme oxygenase 1 gene expression in pulmonary endothelial cells
    • Fogg, S., Agarwal, A., Nick, H.S., and Visner, G.A. 1999. Iron regulates hyperoxia-dependent human heme oxygenase 1 gene expression in pulmonary endothelial cells. Am. J. Respir. Cell Mol. Biol. 20: 797-804.
    • (1999) Am. J. Respir. Cell Mol. Biol. , vol.20 , pp. 797-804
    • Fogg, S.1    Agarwal, A.2    Nick, H.S.3    Visner, G.A.4
  • 21
    • 0026034934 scopus 로고
    • Endothelium-dependent and -independent vasodilation involving cyclic GMP: Relaxation induced by nitric oxide, carbon monoxide and light
    • Furchgott, R.F., and Jothianandan, D. 1991. Endothelium-dependent and -independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels, 28: 52-61.
    • (1991) Blood Vessels , vol.28 , pp. 52-61
    • Furchgott, R.F.1    Jothianandan, D.2
  • 22
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial
    • Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico
    • GISSI-Prevenzione Investigators. 1999. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet, 354: 447-455.
    • (1999) Lancet , vol.354 , pp. 447-455
  • 23
    • 0028903204 scopus 로고
    • Haem oxygenase activity in blood vessel homogenates as measured by carbon monoxide production
    • Grundemar, L., Johansson, M.B., Ekelund, M., Hogestatt, E.D. 1995. Haem oxygenase activity in blood vessel homogenates as measured by carbon monoxide production. Acta Physiol. Scand. 153: 203-204.
    • (1995) Acta Physiol. Scand. , vol.153 , pp. 203-204
    • Grundemar, L.1    Johansson, M.B.2    Ekelund, M.3    Hogestatt, E.D.4
  • 24
    • 0028068186 scopus 로고
    • Free radicals, antioxidants, and human disease: Curiosity, cause, or consequence?
    • Halliwell, B. 1994. Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? Lancet, 344: 721-724.
    • (1994) Lancet , vol.344 , pp. 721-724
    • Halliwell, B.1
  • 25
    • 0029954653 scopus 로고    scopus 로고
    • Bilirubin has widespread inhibitory effects on protein phosphorylation
    • Hansen, T.W., Mathiesen, S.B., and Walaas, S.I. 1996. Bilirubin has widespread inhibitory effects on protein phosphorylation. Pediatr. Res. 39: 1072-1077.
    • (1996) Pediatr. Res. , vol.39 , pp. 1072-1077
    • Hansen, T.W.1    Mathiesen, S.B.2    Walaas, S.I.3
  • 26
    • 0033570168 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 suppresses venular leukocyte adhesion elicited by oxidative stress: Role of bilirubin generated by the enzyme
    • Hayashi, S., Takamiya, R., Yamaguchi, T., Matsumoto, K., Tojo, S.J., Tamatani, T., Kitajima, M., Makino, N., Ishimura, Y., and Suematsu, M. et al. 1999, Induction of heme oxygenase-1 suppresses venular leukocyte adhesion elicited by oxidative stress: role of bilirubin generated by the enzyme. Circ. Res. 85: 663-671.
    • (1999) Circ. Res. , vol.85 , pp. 663-671
    • Hayashi, S.1    Takamiya, R.2    Yamaguchi, T.3    Matsumoto, K.4    Tojo, S.J.5    Tamatani, T.6    Kitajima, M.7    Makino, N.8    Ishimura, Y.9    Suematsu, M.10
  • 27
    • 0141505046 scopus 로고    scopus 로고
    • Heme oxygenase and antioxidant status in cultured aortic endothelial cells isolated from atherosclerosis-susceptible and -resistant Japanese quail
    • Hoekstra, K.A., Godin, D.V., Kurtu, J., and Cheng, K.M. 2003a. Heme oxygenase and antioxidant status in cultured aortic endothelial cells isolated from atherosclerosis-susceptible and -resistant Japanese quail. Mol. Cell. Biochem. 252: 253-262.
    • (2003) Mol. Cell. Biochem. , vol.252 , pp. 253-262
    • Hoekstra, K.A.1    Godin, D.V.2    Kurtu, J.3    Cheng, K.M.4
  • 28
    • 0344943250 scopus 로고    scopus 로고
    • Effect of oxidant-induced injury on heme oxygenase and glutathione in cultured aortic endothelial cells isolated from atherosclerosis-susceptible and -resistant Japanese quail
    • Hoekstra, K.A., Godin, D.V., Kurtu, J., and Cheng, K.M. 2003b. Effect of oxidant-induced injury on heme oxygenase and glutathione in cultured aortic endothelial cells isolated from atherosclerosis-susceptible and -resistant Japanese quail. Mol. Cell. Biochem. 254: 61-71.
    • (2003) Mol. Cell. Biochem. , vol.254 , pp. 61-71
    • Hoekstra, K.A.1    Godin, D.V.2    Kurtu, J.3    Cheng, K.M.4
  • 29
    • 0028851667 scopus 로고
    • Inhibition of metal-catalyzed oxidation of low-density lipoprotein by free and albumin-bound bilirubin
    • Hulea, S.A., Wasowicz, E., and Kummerow, F.A. 1995. Inhibition of metal-catalyzed oxidation of low-density lipoprotein by free and albumin-bound bilirubin. Biochim. Biophys. Acta, 1259: 29-38.
    • (1995) Biochim. Biophys. Acta , vol.1259 , pp. 29-38
    • Hulea, S.A.1    Wasowicz, E.2    Kummerow, F.A.3
  • 30
    • 0026529972 scopus 로고
    • Importance of histidine residue 25 of rat heme oxygenase for its catalytic activity
    • Ishikawa, K., Sato, M., Ito, M., and Yoshida, T. 1992. Importance of histidine residue 25 of rat heme oxygenase for its catalytic activity. Biochem. Biophys. Res. Commun. 182: 981-986.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 981-986
    • Ishikawa, K.1    Sato, M.2    Ito, M.3    Yoshida, T.4
  • 31
    • 0030930697 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL
    • Ishikawa, K., Navab, M., Leitinger, N., Fogelman, A.M., and Lusis, A.J. 1997. Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. J. Clin. Invest. 100: 1209-1216.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1209-1216
    • Ishikawa, K.1    Navab, M.2    Leitinger, N.3    Fogelman, A.M.4    Lusis, A.J.5
  • 32
    • 0032548858 scopus 로고    scopus 로고
    • Identification of histidine 45 as the axial heme iron ligand of heme oxygenase-2
    • Ishikawa, K., Matera, K.M., Zhou, H., Fujii, H., Sato, M., et al. 1998. Identification of histidine 45 as the axial heme iron ligand of heme oxygenase-2. J. Biol. Chem. 273: 4317-4322.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4317-4322
    • Ishikawa, K.1    Matera, K.M.2    Zhou, H.3    Fujii, H.4    Sato, M.5
  • 34
    • 0035896220 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice
    • Ishikawa, K., Sugawara, D., Wang, X.P., Suzuki, K., Itabe, H., Maruyama, Y., and Lusis, AJ. 2001b. Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice. Circ. Res. 88: 506-512.
    • (2001) Circ. Res. , vol.88 , pp. 506-512
    • Ishikawa, K.1    Sugawara, D.2    Wang, X.P.3    Suzuki, K.4    Itabe, H.5    Maruyama, Y.6    Lusis, A.J.7
  • 36
    • 0035949615 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice
    • Juan, S.H., Lee, T.S., Tseng, K.W., Liou, J.Y., Shyue, S.K., Wu, K.K., and Chau, L.Y 2001. Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation, 104: 1519-1525.
    • (2001) Circulation , vol.104 , pp. 1519-1525
    • Juan, S.H.1    Lee, T.S.2    Tseng, K.W.3    Liou, J.Y.4    Shyue, S.K.5    Wu, K.K.6    Chau, L.Y.7
  • 37
    • 0035022958 scopus 로고    scopus 로고
    • Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors
    • Kaide, J.I., Zhang, F., Wei, Y., Jiang, H., Yu, C., et al. 2001. Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors. J. Clin. Invest. 107: 1163-1171.
    • (2001) J. Clin. Invest. , vol.107 , pp. 1163-1171
    • Kaide, J.I.1    Zhang, F.2    Wei, Y.3    Jiang, H.4    Yu, C.5
  • 39
    • 0029153361 scopus 로고
    • Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action
    • Keaney, J.F., Jr., and Vita, J.A. 1995. Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action. Prog. Cardiovasc. Dis. 38: 129-154.
    • (1995) Prog. Cardiovasc. Dis. , vol.38 , pp. 129-154
    • Keaney Jr., J.F.1    Vita, J.A.2
  • 40
    • 0024497521 scopus 로고
    • Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite
    • Keyse, S.M., and Tyrrell, R.M. 1989. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc. Nat. Acad. Sci. U.S.A. 86: 99-103.
    • (1989) Proc. Nat. Acad. Sci. U.S.A. , vol.86 , pp. 99-103
    • Keyse, S.M.1    Tyrrell, R.M.2
  • 41
    • 0025271438 scopus 로고
    • Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365 nm) radiation: Evidence for the involvement of the hydroxyl radical
    • Keyse, S.M., and Tyrrell, R.M. 1990. Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365 nm) radiation: evidence for the involvement of the hydroxyl radical. Carcinogenesis, 11: 787-791.
    • (1990) Carcinogenesis , vol.11 , pp. 787-791
    • Keyse, S.M.1    Tyrrell, R.M.2
  • 42
    • 0032960103 scopus 로고    scopus 로고
    • Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels
    • Kozma, F., Johnson, R.A., Zhang, F., Yu, C., Tong, X., and Nasjletti, A. 1999. Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels. Am. J. Physiol. 276: R1087-R1094.
    • (1999) Am. J. Physiol. , vol.276
    • Kozma, F.1    Johnson, R.A.2    Zhang, F.3    Yu, C.4    Tong, X.5    Nasjletti, A.6
  • 43
    • 0026079020 scopus 로고
    • Receptors for modified low-density lipoproteins on human endothelial cells: Different recognition for acetylated low-density lipoprotein and oxidized low-density lipoprotein
    • Kume, N., Arai, H., Kawai, C., and Kita, T. 1991. Receptors for modified low-density lipoproteins on human endothelial cells: different recognition for acetylated low-density lipoprotein and oxidized low-density lipoprotein. Biochim. Biophys. Acta, 1091: 63-67.
    • (1991) Biochim. Biophys. Acta , vol.1091 , pp. 63-67
    • Kume, N.1    Arai, H.2    Kawai, C.3    Kita, T.4
  • 44
    • 0021278023 scopus 로고
    • Hepatic heme metabolism: Possible role of biliverdin in the regulation of heme oxygenase activity
    • Kutty, R.K., and Maines, M.D. 1984. Hepatic heme metabolism: possible role of biliverdin in the regulation of heme oxygenase activity. Biochem. Biophys. Res. Commun. 122: 40-46.
    • (1984) Biochem. Biophys. Res. Commun. , vol.122 , pp. 40-46
    • Kutty, R.K.1    Maines, M.D.2
  • 45
    • 0026035905 scopus 로고
    • Bilirubin inhibits the activation of superoxide-producing NADPH oxidase in a neutrophil cell-free system
    • Kwak, J.Y., Takeshige, K., Cheung, B.S., and Minakami, S. 1991. Bilirubin inhibits the activation of superoxide-producing NADPH oxidase in a neutrophil cell-free system. Biochem. Biophys. Acta, 1076: 369-373.
    • (1991) Biochem. Biophys. Acta , vol.1076 , pp. 369-373
    • Kwak, J.Y.1    Takeshige, K.2    Cheung, B.S.3    Minakami, S.4
  • 46
    • 0028307310 scopus 로고
    • Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene
    • Lavrovsky, Y., Schwartzman, M.L., Levere, R.D., Kappas, A., and Abraham, N.G. 1994. Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc. Natl. Acad. Sci. U.S.A. 91: 5987-5991.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 5987-5991
    • Lavrovsky, Y.1    Schwartzman, M.L.2    Levere, R.D.3    Kappas, A.4    Abraham, N.G.5
  • 47
    • 0031041377 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
    • Lee, P.J., Jiang, B.H., Chin, B.Y., Iyer, N.V., Alam, J., Semenza, G.L., and Choi, A.M. 1997. Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia.. J. Biol. Chem. 272: 5375-5381.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5375-5381
    • Lee, P.J.1    Jiang, B.H.2    Chin, B.Y.3    Iyer, N.V.4    Alam, J.5    Semenza, G.L.6    Choi, A.M.7
  • 50
    • 0028331627 scopus 로고
    • The structure, organization and differential expression of the gene encoding rat heme oxygenase-2
    • McCoubrey, W.K., Jr., and Maines, M.D. 1994. The structure, organization and differential expression of the gene encoding rat heme oxygenase-2. Gene, 139: 155-161.
    • (1994) Gene , vol.139 , pp. 155-161
    • McCoubrey Jr., W.K.1    Maines, M.D.2
  • 51
    • 8544246393 scopus 로고    scopus 로고
    • Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3
    • McCoubrey, W.K., Jr., Huang, T.J., and Maines, M.D. 1997. Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur. J. Biochem. 247: 725-732.
    • (1997) Eur. J. Biochem. , vol.247 , pp. 725-732
    • McCoubrey Jr., W.K.1    Huang, T.J.2    Maines, M.D.3
  • 52
    • 0030923630 scopus 로고    scopus 로고
    • The heme oxygenase system: A regulator of second messenger gases
    • Maines, M.D. 1997. The heme oxygenase system: a regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37: 517-554.
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 517-554
    • Maines, M.D.1
  • 53
    • 0006476631 scopus 로고
    • Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity
    • Maines, M.D., and Kappas, A. 1974. Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity. Proc. Natl. Acad. Sci. U.S.A. 71: 4293-4297.
    • (1974) Proc. Natl. Acad. Sci. U.S.A. , vol.71 , pp. 4293-4297
    • Maines, M.D.1    Kappas, A.2
  • 54
    • 0017641237 scopus 로고
    • Regulation of heme pathway enzymes and cellular glutathione content by metals that do not chelate with tetrapyrroles: Blockade of metal effects by thiols
    • Maines, M.D., and Kappas, A. 1977. Regulation of heme pathway enzymes and cellular glutathione content by metals that do not chelate with tetrapyrroles: blockade of metal effects by thiols. Proc. Natl. Acad. Sci. U.S.A. 74: 1875-1878.
    • (1977) Proc. Natl. Acad. Sci. U.S.A. , vol.74 , pp. 1875-1878
    • Maines, M.D.1    Kappas, A.2
  • 56
    • 0033756130 scopus 로고    scopus 로고
    • Association of serum bilirubin concentration with risk of coronary artery disease
    • Mayer, M. 2000. Association of serum bilirubin concentration with risk of coronary artery disease. Clin. Chem. 46: 1723-1727.
    • (2000) Clin. Chem. , vol.46 , pp. 1723-1727
    • Mayer, M.1
  • 58
    • 0032897558 scopus 로고    scopus 로고
    • Antioxidant and cytotoxic effects of bilirubin on neonatal erythrocytes
    • Mireles, L.C., Lum, M.A., and Dennery, P.A. 1999. Antioxidant and cytotoxic effects of bilirubin on neonatal erythrocytes. Pediatr. Res. 45: 355-362.
    • (1999) Pediatr. Res. , vol.45 , pp. 355-362
    • Mireles, L.C.1    Lum, M.A.2    Dennery, P.A.3
  • 59
    • 0032494085 scopus 로고    scopus 로고
    • Heme oxygenase-1-derived carbon monoxide contributes to the suppression of acute hypertensive responses in vivo
    • Motterlini, R., Gonzales, A., Foresti, R., Clark, J.E., Green, C.J., and Winslow, R.M. 1998. Heme oxygenase-1-derived carbon monoxide contributes to the suppression of acute hypertensive responses in vivo. Circ. Res. 83: 568-577.
    • (1998) Circ. Res. , vol.83 , pp. 568-577
    • Motterlini, R.1    Gonzales, A.2    Foresti, R.3    Clark, J.E.4    Green, C.J.5    Winslow, R.M.6
  • 60
    • 0027498438 scopus 로고
    • Bioactivity of heme and its containment
    • Muller-Eberhard, U., and Fraig, M. 1993. Bioactivity of heme and its containment. Am. J. Hematol. 42: 59-62.
    • (1993) Am. J. Hematol. , vol.42 , pp. 59-62
    • Muller-Eberhard, U.1    Fraig, M.2
  • 61
    • 0027452195 scopus 로고
    • A beneficial role of bile pigments as an endogenous tissue protector: Anti-complement effects of biliverdin and conjugated bilirubin
    • Nakagami, T., Toyomura, K., Kinoshita, T., and Morisawa, S. 1993. A beneficial role of bile pigments as an endogenous tissue protector: anti-complement effects of biliverdin and conjugated bilirubin. Biochim. Biophys. Acta, 1158: 189-193.
    • (1993) Biochim. Biophys. Acta , vol.1158 , pp. 189-193
    • Nakagami, T.1    Toyomura, K.2    Kinoshita, T.3    Morisawa, S.4
  • 62
    • 8944258922 scopus 로고    scopus 로고
    • The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture
    • Navab, M., Berliner, J.A., Watson, A.D., Hama, S.Y., Territo, M.C., et al. 1996. The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture. Arterioscler. Thromb. Vasc. Biol. 16: 831-842.
    • (1996) Arterioscler. Thromb. Vasc. Biol. , vol.16 , pp. 831-842
    • Navab, M.1    Berliner, J.A.2    Watson, A.D.3    Hama, S.Y.4    Territo, M.C.5
  • 63
    • 0028239795 scopus 로고
    • Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation
    • Neuzil, J., and Stocker, R. 1994. Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation. J. Biol. Chem. 269: 16712-16719.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16712-16719
    • Neuzil, J.1    Stocker, R.2
  • 65
  • 67
    • 0027170699 scopus 로고
    • Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate
    • Parhami, F., Fang, Z.T., Fogelman, A.M., Andalibi, A., Territo, M.C., and Berliner, J.A. 1993. Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine monophosphate. J. Clin. Invest. 92: 471-478.
    • (1993) J. Clin. Invest. , vol.92 , pp. 471-478
    • Parhami, F.1    Fang, Z.T.2    Fogelman, A.M.3    Andalibi, A.4    Territo, M.C.5    Berliner, J.A.6
  • 68
    • 0035746067 scopus 로고    scopus 로고
    • Influences of alpha-tocopherol on cholesterol metabolism and fatty streak development in apolipoprotein E-deficient mice fed an atherogenic diet
    • Peluzio, M.C., Homem, A.P., Cesar, G.C., Azevedo, G.S., Amorim, R., et al. 2001. Influences of alpha-tocopherol on cholesterol metabolism and fatty streak development in apolipoprotein E-deficient mice fed an atherogenic diet. Braz. J. Med. Biol. Res. 34: 1539-1545.
    • (2001) Braz. J. Med. Biol. Res. , vol.34 , pp. 1539-1545
    • Peluzio, M.C.1    Homem, A.P.2    Cesar, G.C.3    Azevedo, G.S.4    Amorim, R.5
  • 69
    • 0037097844 scopus 로고    scopus 로고
    • Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth
    • Peyton, K.J., Reyna, S.V., Chapman, G.B., Ensenat, D., Liu, X.M., et al. 2002. Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth. Blood, 99: 4443-4448.
    • (2002) Blood , vol.99 , pp. 4443-4448
    • Peyton, K.J.1    Reyna, S.V.2    Chapman, G.B.3    Ensenat, D.4    Liu, X.M.5
  • 70
    • 0025281029 scopus 로고
    • Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells. Upregulation by phorbol esters
    • Pitas, R.E. 1990. Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells. Upregulation by phorbol esters. J. Biol. Chem. 265: 12722-12 727.
    • (1990) J. Biol. Chem. , vol.265 , pp. 12722-12727
    • Pitas, R.E.1
  • 71
    • 0034063564 scopus 로고    scopus 로고
    • Heme oxygenase-1 is a cyclic GMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide
    • Polte, T., Abate, A., Dennery, P.A., and Schroder, H. 2000. Heme oxygenase-1 is a cyclic GMP-inducible endothelial protein and mediates the cytoprotective action of nitric oxide. Arterioscler. Thromb. Vasc. Biol. 20: 1209-1215.
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 1209-1215
    • Polte, T.1    Abate, A.2    Dennery, P.A.3    Schroder, H.4
  • 72
    • 0030886054 scopus 로고    scopus 로고
    • Reduced stress defense in heme oxygenase 1-deficient cells
    • Poss, K.D., and Tonegawa S. 1997a. Reduced stress defense in heme oxygenase 1-deficient cells. Proc. Natl. Acad. Sci. U.S.A. 94: 10 925-10 930.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 10925-10930
    • Poss, K.D.1    Tonegawa, S.2
  • 73
    • 0030886381 scopus 로고    scopus 로고
    • Heme oxygenase 1 is required for mammalian iron reutilization
    • Poss, K.D., and Tonegawa, S. 1997b. Heme oxygenase 1 is required for mammalian iron reutilization. Proc. Natl. Acad. Sci. U.S.A. 94: 10919-10924.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 10919-10924
    • Poss, K.D.1    Tonegawa, S.2
  • 74
    • 0035834012 scopus 로고    scopus 로고
    • Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs
    • Quan, S., Yang, L., Abraham, N.G., and Kappas, A. 2001. Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs. Proc. Natl. Acad. Sci. U.S.A. 98: 12 203-12 208.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 12203-12208
    • Quan, S.1    Yang, L.2    Abraham, N.G.3    Kappas, A.4
  • 75
    • 0026526023 scopus 로고
    • Ferritin as a source of iron for oxidative damage
    • Reif, D.W. 1992. Ferritin as a source of iron for oxidative damage. Free Radic. Biol. Med. 12: 417-427.
    • (1992) Free Radic. Biol. Med. , vol.12 , pp. 417-427
    • Reif, D.W.1
  • 76
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature (London), 362: 801-809.
    • (1993) Nature (London) , vol.362 , pp. 801-809
    • Ross, R.1
  • 77
    • 0031767014 scopus 로고    scopus 로고
    • Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of haeme oxygenase-1
    • Sammut, I.A., Foresti, R., Clark, J.E., Exon, D.J., Vesely, M.J., et al. 1998. Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of haeme oxygenase-1. Br. J. Pharmacol. 125: 1437-1444.
    • (1998) Br. J. Pharmacol. , vol.125 , pp. 1437-1444
    • Sammut, I.A.1    Foresti, R.2    Clark, J.E.3    Exon, D.J.4    Vesely, M.J.5
  • 78
    • 0019376275 scopus 로고
    • The potent heme oxygenase inducing action of arsenic and parasiticidal arsenicals
    • Sardana, M.K., Drummond, G.S., Sassa, S., and Kappas, A. 1981. The potent heme oxygenase inducing action of arsenic and parasiticidal arsenicals. Pharmacology, 23: 247-253.
    • (1981) Pharmacology , vol.23 , pp. 247-253
    • Sardana, M.K.1    Drummond, G.S.2    Sassa, S.3    Kappas, A.4
  • 79
    • 0020479017 scopus 로고
    • Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells
    • Sardana, M.K., Sassa, S., and Kappas, A. 1982. Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells. J. Biol. Chem. 257: 4806-4811.
    • (1982) J. Biol. Chem. , vol.257 , pp. 4806-4811
    • Sardana, M.K.1    Sassa, S.2    Kappas, A.3
  • 80
    • 0034050767 scopus 로고    scopus 로고
    • Enhanced accumulation of pericardial fluid ferritin in patients with coronary artery disease
    • Selmeci, L., Antal, M., Horkay, F., Merkely, B., Szokodi, I., et al. 2000. Enhanced accumulation of pericardial fluid ferritin in patients with coronary artery disease. Coron. Artery Dis. 11: 53-56.
    • (2000) Coron. Artery Dis. , vol.11 , pp. 53-56
    • Selmeci, L.1    Antal, M.2    Horkay, F.3    Merkely, B.4    Szokodi, I.5
  • 81
    • 0018637428 scopus 로고
    • Mechanism of increase of heme oxygenase activity induced by hemin in cultured pig alveolar macrophages
    • Shibahara, S., Yoshida, T., and Kikuchi, G. 1979. Mechanism of increase of heme oxygenase activity induced by hemin in cultured pig alveolar macrophages. Arch. Biochem. Biophys. 197: 607-617.
    • (1979) Arch. Biochem. Biophys. , vol.197 , pp. 607-617
    • Shibahara, S.1    Yoshida, T.2    Kikuchi, G.3
  • 82
    • 0027532668 scopus 로고
    • Functional analysis of cDNAs for two types of human heme oxygenase and evidence for their separate regulation
    • Tokyo
    • Shibahara, S., Yoshizawa, M., Suzuki, H., Takeda, K., Meguro, K., and Endo, K. 1993. Functional analysis of cDNAs for two types of human heme oxygenase and evidence for their separate regulation. J. Biochem. (Tokyo) 113: 214-218.
    • (1993) J. Biochem. , vol.113 , pp. 214-218
    • Shibahara, S.1    Yoshizawa, M.2    Suzuki, H.3    Takeda, K.4    Meguro, K.5    Endo, K.6
  • 83
    • 0034883783 scopus 로고    scopus 로고
    • Heme oxygenase: A font of multiple messengers
    • Snyder, S.H., and Baranano, D.E. 2001. Heme oxygenase: a font of multiple messengers. Neuropsychopharmacology, 25: 294-298.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 294-298
    • Snyder, S.H.1    Baranano, D.E.2
  • 84
    • 0026039122 scopus 로고
    • Antioxidants and atherosclerosis. A current assessment
    • Steinberg, D. 1991. Antioxidants and atherosclerosis. A current assessment. Circulation, 84: 1420-1425.
    • (1991) Circulation , vol.84 , pp. 1420-1425
    • Steinberg, D.1
  • 85
    • 0029062014 scopus 로고
    • Clinical trials of antioxidants in atherosclerosis: Are we doing the right thing?
    • Steinberg, D. 1995. Clinical trials of antioxidants in atherosclerosis: are we doing the right thing? Lancet, 346: 36-38.
    • (1995) Lancet , vol.346 , pp. 36-38
    • Steinberg, D.1
  • 86
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
    • Stephens, N.G., Parsons, A., Schofield, P.M., Kelly, F., Cheeseman, K., and Mitchinson, M.J. 1996. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet, 347: 781-786.
    • (1996) Lancet , vol.347 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3    Kelly, F.4    Cheeseman, K.5    Mitchinson, M.J.6
  • 87
    • 0025368527 scopus 로고
    • Induction of haem oxygenase as a defense against oxidative stress
    • Stocker, R. 1990. Induction of haem oxygenase as a defense against oxidative stress. Free Radic. Res. Commun. 9: 101-112.
    • (1990) Free Radic. Res. Commun. , vol.9 , pp. 101-112
    • Stocker, R.1
  • 88
    • 0023132858 scopus 로고
    • Bilirubin is an antioxidant of possible physiological importance
    • Washington, D.C.
    • Stocker, R., Yamamoto, Y., McDonagh, A.F., Glazer, A.N., and Ames, B.N. 1987. Bilirubin is an antioxidant of possible physiological importance. Science (Washington, D.C.), 235: 1043-1046.
    • (1987) Science , vol.235 , pp. 1043-1046
    • Stocker, R.1    Yamamoto, Y.2    McDonagh, A.F.3    Glazer, A.N.4    Ames, B.N.5
  • 89
    • 0029121091 scopus 로고
    • Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication
    • Stroes, E.S., Koomans, H.A., de Bruin, T.W., and Rabelink, T.J. 1995. Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication. Lancet, 346: 467-471.
    • (1995) Lancet , vol.346 , pp. 467-471
    • Stroes, E.S.1    Koomans, H.A.2    De Bruin, T.W.3    Rabelink, T.J.4
  • 90
    • 0023709218 scopus 로고
    • Induction of heme oxygenase in rat hepatoma cells by exposure to heavy metals and hyperthermia
    • Taketani, S., Kohno, H., Yoshinaga, T., and Tokunaga, R. 1988. Induction of heme oxygenase in rat hepatoma cells by exposure to heavy metals and hyperthermia. Biochemistry, 17: 665-672.
    • (1988) Biochemistry , vol.17 , pp. 665-672
    • Taketani, S.1    Kohno, H.2    Yoshinaga, T.3    Tokunaga, R.4
  • 91
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • Tenhunen, R., Marver, H.S., and Schmid, R. 1968. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl. Acad. Sci. U.S.A. 61: 748-755.
    • (1968) Proc. Natl. Acad. Sci. U.S.A. , vol.61 , pp. 748-755
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 92
    • 0014670945 scopus 로고
    • Microsomal heme oxygenase. Characterization of the enzyme
    • Tenhunen, R., Marver, H.S., and Schmid, R. 1969a. Microsomal heme oxygenase. Characterization of the enzyme. J. Biol. Chem. 244: 6388-6394.
    • (1969) J. Biol. Chem. , vol.244 , pp. 6388-6394
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 94
    • 0035960644 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation
    • Tulis, D.A., Durante, W., Liu, X., Evans, A.J., Peyton, K.J., and Schafer, A.I. 2001. Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation. Circulation, 104: 2710-2715.
    • (2001) Circulation , vol.104 , pp. 2710-2715
    • Tulis, D.A.1    Durante, W.2    Liu, X.3    Evans, A.J.4    Peyton, K.J.5    Schafer, A.I.6
  • 95
    • 0027458551 scopus 로고
    • Carbon monoxide: A putative neural messenger
    • Washington, D.C.
    • Verma, A., Hirsch, D.J., Glatt, C.E., Ronnett, G.V., and Snyder, S.H. 1993. Carbon monoxide: a putative neural messenger. Science (Washington, D.C.), 259: 381-384.
    • (1993) Science , vol.259 , pp. 381-384
    • Verma, A.1    Hirsch, D.J.2    Glatt, C.E.3    Ronnett, G.V.4    Snyder, S.H.5
  • 96
    • 0027255106 scopus 로고
    • Oxidative stress resulting from ultraviolet a irradiation of human skin fibroblasts leads to a heme oxygenase-dependent increase in ferritin
    • Vile, G.F., and Tyrrell, R.M. 1993. Oxidative stress resulting from ultraviolet A irradiation of human skin fibroblasts leads to a heme oxygenase-dependent increase in ferritin. J. Biol. Chem. 268: 14678-14681.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14678-14681
    • Vile, G.F.1    Tyrrell, R.M.2
  • 97
    • 0030856625 scopus 로고    scopus 로고
    • Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells
    • Wagner, C.T., Durante, W., Christodoulides, N., Hellums, J.D., and Schafer, A.I. 1997. Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells. J. Clin. Invest. 100: 589-596.
    • (1997) J. Clin. Invest. , vol.100 , pp. 589-596
    • Wagner, C.T.1    Durante, W.2    Christodoulides, N.3    Hellums, J.D.4    Schafer, A.I.5
  • 98
    • 0031935208 scopus 로고    scopus 로고
    • Expression of heme oxygenase-1 in atherosclerotic lesions
    • Wang, L.J., Lee, T.S., Lee, F.Y., Pai, R.C., and Chau, L.Y. 1998. Expression of heme oxygenase-1 in atherosclerotic lesions. Am. J. Pathol. 152: 711-20.
    • (1998) Am. J. Pathol. , vol.152 , pp. 711-720
    • Wang, L.J.1    Lee, T.S.2    Lee, F.Y.3    Pai, R.C.4    Chau, L.Y.5
  • 100
    • 0030045835 scopus 로고    scopus 로고
    • Heme oxygenase: A novel target for the modulation of the inflammatory response
    • Willis, D., Moore, A.R., Frederik, R., and Willoughby, D.A. 1996. Heme oxygenase: a novel target for the modulation of the inflammatory response. Nat. Med. 2: 87-90.
    • (1996) Nat. Med. , vol.2 , pp. 87-90
    • Willis, D.1    Moore, A.R.2    Frederik, R.3    Willoughby, D.A.4
  • 101
    • 0026333959 scopus 로고
    • Role of oxidized low density lipoprotein in atherogenesis
    • Witztum, J.L., and Steinberg, D. 1991. Role of oxidized low density lipoprotein in atherogenesis. J. Clin. Invest. 88: 1785-1792.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1785-1792
    • Witztum, J.L.1    Steinberg, D.2
  • 102
    • 0032893958 scopus 로고    scopus 로고
    • Oxidative stress causes enhanced endothelial cell injury in human gene oxygenase-1 deficiency
    • Yachie, A., Niida, Y., Wada, T., Igarashi, N., Kaneda, H., et al. 1999. Oxidative stress causes enhanced endothelial cell injury in human gene oxygenase-1 deficiency. J. Clin. Invest. 103: 129-135.
    • (1999) J. Clin. Invest. , vol.103 , pp. 129-135
    • Yachie, A.1    Niida, Y.2    Wada, T.3    Igarashi, N.4    Kaneda, H.5
  • 103
    • 0033925281 scopus 로고    scopus 로고
    • Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema
    • Yamada, N., Yamaya, M., Okinaga, S., Nakayama, K., Sekizawa, K., Shibahara, S., and Sasaki, H. 2000. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am. J. Hum. Genet. 66: 187-195.
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 187-195
    • Yamada, N.1    Yamaya, M.2    Okinaga, S.3    Nakayama, K.4    Sekizawa, K.5    Shibahara, S.6    Sasaki, H.7
  • 104
    • 0027328231 scopus 로고
    • Induction of stress proteins in mouse peritoneal macrophages by oxidized low-density lipoprotein
    • Yamaguchi, M., Sato, H., and Bannai, S. 1993. Induction of stress proteins in mouse peritoneal macrophages by oxidized low-density lipoprotein. Biochem. Biophys. Res. Commun. 193: 1198-1201.
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 1198-1201
    • Yamaguchi, M.1    Sato, H.2    Bannai, S.3
  • 105
    • 0029855273 scopus 로고    scopus 로고
    • Effect of nitric oxide on heme metabolism in pulmonary artery endothelial cells
    • Yee, E.L., Pitt, B.R., Billiar, T.R., and Kim, Y.M. 1996. Effect of nitric oxide on heme metabolism in pulmonary artery endothelial cells. Am. J. Physiol. 271: L512-L518.
    • (1996) Am. J. Physiol. , vol.271
    • Yee, E.L.1    Pitt, B.R.2    Billiar, T.R.3    Kim, Y.M.4
  • 106
    • 0141706806 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling
    • Yet, S.F., Layne, M.D., Liu, X., Chen, Y.H., Ith, B., Sibinga, N.B., and Perrella, M. A. 2003. Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling. FASEB J. 17: 1759-1761.
    • (2003) FASEB J. , vol.17 , pp. 1759-1761
    • Yet, S.F.1    Layne, M.D.2    Liu, X.3    Chen, Y.H.4    Ith, B.5    Sibinga, N.B.6    Perrella, M.A.7
  • 107
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin E supplementation and cardiovascular events in high-risk patients
    • The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf, S., Dagenais, G., Pogue, J., Bosch, J., and Sleight, P. 2000. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N. Engl. J. Med. 342: 154-160.
    • (2000) N. Engl. J. Med. , vol.342 , pp. 154-160
    • Yusuf, S.1    Dagenais, G.2    Pogue, J.3    Bosch, J.4    Sleight, P.5
  • 108
    • 0030923925 scopus 로고    scopus 로고
    • Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice
    • Zhang, S.H., Reddick, R.L., Avdievich, E., Surles, L.K., Jones, R.G., et al. 1997. Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice. J. Clin. Invest. 99: 2858-2866.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2858-2866
    • Zhang, S.H.1    Reddick, R.L.2    Avdievich, E.3    Surles, L.K.4    Jones, R.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.