RAGE as a receptor of HMGB1 (Amphoterin): Roles in health and disease

Current Molecular Medicine

Volumn 7, Issue 8, 2007, Pages 725-734

  Rauvala, Heikki ^a   Rouhiainen, Ari ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

HMGB1 expression; Inflammation; MAPK kinases; Plasticity; RAGE binding region

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; DNA BINDING PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN;

ATHEROSCLEROSIS; CANCER INVASION; CELL COMMUNICATION; CELL FUNCTION; CELL MIGRATION; CELL MOTILITY; CELL TYPE; CHRONIC INFLAMMATION; CYTOSKELETON; DISEASE ASSOCIATION; EXTRACELLULAR SPACE; GENE OVEREXPRESSION; GENETIC CONSERVATION; HUMAN; MOLECULAR MECHANICS; NEOPLASM; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN STRUCTURE; RECEPTOR BINDING; REGULATORY MECHANISM; REVIEW; RHEUMATOID ARTHRITIS; SEPSIS; SIGNAL TRANSDUCTION; STROKE; TUMOR GROWTH;

ANIMALS; DISEASE; HEALTH; HMGB1 PROTEIN; HUMANS; NEURONAL PLASTICITY; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 38349176286     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652407783220750     Document Type: Review

References (126)

1. Hock, R., Furusawa, T., Ueda, T. and Bustin, M. (2007) Trends Cell Biol., 17, 72-79.
2. Goodwin, G.H. and Johns, E.W. (1973) Eur. J. Biochem., 40, 215-219.
3. Rauvala, H. and Pihlaskari, R. (1987) J. Biol. Chem., 262, 16625-16635.
4. Rauvala, H., Merenmies, J., Pihlaskari, R., Korkolainen, M., Huhtala, M.-L. and Panula, P. (1988) J. Cell Biol., 107, 2293-2305.
5. Bianchi, M.E., Beltrame, M. and Paonessa, G. (1989) Science, 243, 1056-1059.
6. Merenmies, J., Pihlaskari, R., Laitinen, J., Wartiovaara, J. and Rauvala, H. (1991) J. Biol. Chem., 266, 16722-16729.
7. Parkkinen, J., Raulo, E., Merenmies, J., Nolo, R., Kajander, E.O., Baumann, M. and Rauvala, H. (1993) J. Biol. Chem., 268 19726-19738.
8. Bustin, M. (2001) Trends Biochem. Sci., 26, 152-153.
9. Schmidt, A.M., Vianna, M., Gerlach, M., Brett, R.J., Kao, J., Esposito, C., Hegarty, H., Hurley, W. and Clauss, M. (1992) J. Biol. Chem., 267, 14987-14997.
10. Schmidt, A.M., Yan, S.D., Yan, S.F. and Stem, D.M. (2000) Biochim Biophys. Acta, 1498, 99-111.
11. Hori, O., Brett, J., Slattery, T., Cao, R., Zhang, J., Chen, J.X., Nagashima, M., Lundh, E.R., Vijay, S., Nitecki, D., Morser, J., Stern, D. and Schmidt, A.M. (1995) J. Biol Chem., 270, 25752-25761.
12. Read, C.M., Cary, P.D., Crane-Robinson, C., Driscoll, P.C. and Norman, D.G. (1993) Nucleic Acids Res., 21, 3427-3436.
13. Weir, H.M., Kraulis, P.J., Hill, C.S., Raine, A.R., Laue, E.D. and Thomas, J.O. (1993) EMBO J., 12, 1311-1319.
14. Hardman, C.H., Broadhurst, R.W., Raine, A.R., Grasser, K.D., Thomas, J.O. and Laue, E.D. (1995) Biochemistry, 34, 16596-16607.
15. Cardin, A.D. and Weintraub, H.J. (1989) Arteriosclerosis, 9, 21-32.
16. Huttunen, H.J. and Rauvala, H. (2004) J. Int. Med., 255, 351-366.
17. Kallijarvi, J., Haltia, M. and Baumann, M.H. (2001) Biochemistry, 40, 10032-10037.
18. Lotze, M.T. and Tracey, K.J. (2005) Nat. Rev. Immunol., 5, 331-342.
19. Sparatore, B., Petrone, M., Passalacqua, M., Pedrazzi, M., Gaggero, D., Pontremoli, S. and Melloni, E. (2001) Biochem. J., 357, 569-574.
20. Huttunen, H.J., Fages, C., Kuja-Panula, J., Ridley, A.J. and Rauvala, H. (2002) Cancer Res., 62, 4805-4811.
21. Rouhiainen, A., Kuja-Panula, J., Wilkman, E., Pakkanen, J., Stenfors, J., Tuominen, R.K., Lepantalo, M., Carpen, O., Parkkinen, J, and Rauvala, H. (2004) Blood, 104, 1174-1182.
22. Bustin, M. and Neihart, N.K. (1979) Cell, 16, 181-189.
23. Muller, S., Ronfani, L. and Bianchi, M.E. (2004) J. Intern. Med., 255, 332-343.
24. Ulloa, L. and Messmer, D. (2006) Cytokine Growth Factor Rev., 17, 189-201.
25. Wang, H., Bloom, O., Zhang, M., Vishnubhakat, J.M., Ombrellino, M., Che, J., Frazier, A., Yang, H., Ivanova, S., Borovikova, L., Manogue, K.R., Faist E., Abraham, E., Andersson, J., Andersson, U., Molina, P.E., Abumrad, N.N., Sama, A. and Tracey, K.J. (1999) Science, 285, 248-251.
26. Sunden-Cullberg, J., Norrby-Teglund, A., Rouhiainen, A., Rauvala, H., Herman, G., Tracey, K.J., Lee, M.L., Andersson, J., Tokics, L. and Treutiger, C.J. (2005) Crit. Care Med., 33, 564-573.
27. Bonaldi, T.; Talawo, F., Scaffidi, P., Ferrera, D., Porto, A., Bachi, A., Rubartelli, A., Agresti, A. and Bianchi, M.E. (2003) EMBO J., 22, 5551-5560.
28. Gardella, S., Andrei, C., Ferrera, D., Lotti, L.V., Torrisi, M.R., Bianchi, M.E. and Rubartelli, A. (2002) EMBO Rep., 3, 995-1001.
29. Youn, J.H. and Shin, J.S. (2006) J. Immunol., 177, 7889-7897.
30. Passalacqua, M., Zicca, A., Sparatore, B., Patrone, M., Melloni, E. and Pontremoli, S. (1997) FEBS Lett., 400, 275-279.
31. Ito, I., Fukuzawa, J. and Yoshida, M. (2007) J. Biol. Chem., 282, 16336-16344.
32. Ditsworth, D., Zong, W.X. and Thompson, C.B. (2007) J. Biol. Chem., 282, 17845-17854.
33. Huttunen, H.J., Fages, C. and Rauvala, H. (1999) J. Biol. Chem., 274, 19919-19924.
34. Chavakis, T., Bierhaus, A., Al-Fakhri, N., Schneider, D., Witte, S., Linn, T., Nagashima, M., Morser, J., Arnold, B., Preissner, K.T. and Nawroth, P.P. (2003) J. Exp. Med., 198, 1507-1515.
35. Chavakis, E., Hain, A., Vinci, M., Carmona, G., Bianchi, M.E., Vajkoczy, P., Zeiher, A.M., Chavakis, T. and Dimmeler, S. (2007) Circ. Res., 100, 204-212.
36. Orlova, V.V., Choi, E.Y., Xie, C., Chavakis, E., Bierhaus, A., Ihanus, E., Ballantyne, C.M., Gahmberg, C.G., Bianchi, M.E., Nawroth, P.P. and Chavakis, T. (2007) EMBO J., 26, 1129-1139.
37. Kuja-Panula, J., Kiiltomäki, M., Yamashiro, T., Rouhiainen, A. and Rauvala, H. (2003) J. Cell. Biol., 160, 963-973.
38. Huttunen, H.J., Kuja-Panula, J., Sorci, G., Agneletti, A.L., Donato, R. and Rauvala, H. (2000) J. Biol. Chem., 275, 40096-40105.
39. Huttunen, H.J, Kuja-Panula, J. and Rauvala, H. (2002) J. Biol. Chem., 277, 38635-38646.
40. Kim, T., Tao-Cheng, J.H., Eiden, L.E. and Loh, Y.P. (2001) Cell, 106, 499-509.
41. Huh, Y.H., Jeon, S.H. and Yoo, S.H. (2003) J. Biol. Chem., 278, 40581-40589.
42. Ishihara, K., Tsutsumi, K., Kawane, S., Nakajima, M. and Kasaoka, T. (2003) FEBS Lett., 550, 107-113.
43. Lander, H.M., Tauras, J.M., Ogiste, J.S., Hori, O., Moss, R.A. and Schmidt, A.M. (1997) J. Biol. Chem., 272, 17810-17814.
44. Taguchi, A., Blood, D.C., Del Toro, G., Canet, A., Lee, D.C., Qu, W., Tahji, N., Lu, Y., Lalla, E., Fu, C., Hofmann, M.A., Kislinger, T., Ingram, M., Lu, A., Tanaka, H., Hori, O., Ogawa, S., Stem, D.M. and Schmidt, A.M. (2000) Nature, 405, 354-360.
45. Yan, S.D., Chen, X., Fu, J., Chen, M., Zhu, H., Roher, A., Slattery, T., Zhao, L., Nagashima, M., Morser, J., Migheli, A., Nawroth, P., Stern, D. and Schmidt, A.M. (1996) Nature, 382, 685-691.
46. Chaney, M.O., Stine, W.B., Kokjohn, T.A., Kuo, Y.M., Esh, C., Rahman, A., Luehrs, D.C., Schmidt, A.M., Stern, D., Yan, S.D. and Roher, A.E. (2005) Biochim. Biophys. Acta, 1741, 199-205.
47. Xie, J., Burz, D.S., He, W., Bronstein, I.B., Lednev, I.K. and Shekhtman, A. (2007) J. Biol. Chem., 282, 4218-4231.
48. Yonekura, H., Yamamoto, Y., Sakurai, S., Petrova, R.G., Abedin, M.J., Li, H., Yasui, K., Takeuchi, M., Makita, Z., Takasawa, S., Okamoto, H., Watanabe, T. and Yamamoto, H. (2003) Biochem. J., 370, 1097-1109.
49. Liliensiek, B., Weigand, M.A., Bierhaus, A., Nicklas, W., Kasper, M., Hofer, S., Plachky, J., Grone, H.J., Kurschus, F.C., Schmidt, A.M., Yan, S.D., Martin, E., Schleicher, E., Stern, D.M., Hammerling, G.G., Nawroth, P.P. and Arnold, B. (2004) J. Clin. Invest., 113, 1641-1650.
50. Yonekura, H., Yamamoto, Y., Sakurai, S., Watanabe, T. and Yamamoto, H. (2005) J. Pharmacol. Sci., 97, 305-311.
51. Calogero, S., Grassi, F., Aguzzi, A., Voigtiander, T., Ferrier, P., Farrari, S. and Bianchi, M.E. (1999) Nat. Gen., 22, 276-280.
52. Salmivirta, M., Rauvala, H., Elenius, K. and Jalkanen, M. (1992) Exp. Cell. Res., 200, 444-451.
53. Rauvala, H., Huttunen, H.J., Fages, C., Kaksonen, M., Kinnunen, T., Imai, S., Raulo, E. and Kilpelainen, I. (2000) Matrix Biol., 19, 377-387.
54. Hienola, A., Tumova, S., Kulesskiy, E. and Rauvala, H. (2006) J. Cell Biol., 174, 569-580.
55. Milev, P., Chiba, A., Haring, M., Rauvala, H., Schachner, M., Ranscht, B., Margolis, R.K. and Margolis, R.U. (1998) J. Biol. Chem., 273, 6998-7005.
56. Chou, D.K., Evans, J.E. and Jungalwala, F.B. (2001) J. Neurochem., 77, 120-131.
57. Chou, D.K., Zhang, J., Smith, F.I., McCaffery, P. and Jungalwala, F.B. (2004) J. Neurochem., 90, 1389-1401.
58. Kleene, R. and Schachner, M. (2004) Nat. Rev. Neurosci., 5, 195-208.
59. Srikrishna, G., Huttunen, H.J., Johansson, L., Weigle, B., Yamaguchi, Y., Rauvala, H. and Freeze, H.H. (2002) J. Neurochem., 80, 998-1008.
60. Park, J.S., Svetkauskaite; D., Fle, Q., Kim, J.Y., Strassheim, D., Ishizaka, A. and Abraham, E. (2004) J. Biol. Chem., 279, 7370-7377.
61. Rouhiainen, A., Tumova, S., Valmu, L., Kalkkinen, N. and Rauvala, H. (2007) J. Leukoc. Biol., 81, 49-58.
62. Tian, J., Avalos, A.M., Mao, S.Y., Chen, B., Senthil, K., Wu, H., Parroche, P., Drabic, S., Golenbock, D., Sirois, C., Hua, J., An, L.L., Audoly, L., La Rosa, G., Bierhaus, A., Naworth, P., Marshak-Rothstein, A., Crow, M.K.. Fitzgerald, K.A., Latz, E., Kiener, P.A. and Coyle, A.J. (2007) Nat. Immunol., 8, 487-496.
63. Ivanov, S., Dragoi, A.M., Wang, X., Dallacosta, C., Louten, J., Musco, G., Sitia, G., Yap, G.S., Wan, Y., Biron, C.A., Bianchi, M.E., Wang, H. and Chu, W.M. (2007) Blood, 110, 1970-1981.
64. Rong, L.L., Trojaborg,, W., Qu, W., Kostov, K., Yan, S.D., Gooch, C., Szabolcs, M., Hays, A.P. and Schmidt, A.M. (2004) FASEB J., 18, 1812-1817.
65. Rong, L.L., Yan, S.F., Wendt, T., Hans, D., Pachydaki, S, Bucciarelli, L.G., Adebayo, A., Qu, W., Lu, Y., Kostov, K., Lalla, E., Yan, S.D., Gooch, C., Szabolcs, M., Trojaborg, W., Hays, A.P. and Schmidt, A.M. (2004) FASEB J., 18, 1818-1825.
66. Kim, J.B., Sig Choi, J., Yu, Y.M., Nam, K., Piao, C.S., Kim, S.W., Lee, M.H., Han, P.L., Park, J.S. and Lee, J.K. (2006) J. Neurosci., 26, 6413-6421.
67. Pedrazzi, M., Raiteri, L., Bonanno, G., Patrone,M., Ledda, S., Passalacqua, M., Milanese, M., Melloni, E., Raiteri, M., Pontremoli, S. and Sparatore, B. (2006) J. Neurochem., 99, 827-838.
68. Liu, K., Mori, S., Takahashi, H.K., Tomono, Y., Wake, H., Kanke, T., Sato, Y., Hiraga, N., Adachi, N., Yoshino, T. and Nishibori, M. (2007) FASEB J., Epub ahead of print.
69. Agnello, D., Wang, H., Yang, H., Tracey, K.J. and Ghezzi, P. (2002) Cytokine, 18, 231-236.
70. Reizes, O., Lincecum, J., Wang, Z., Goldberger, O., Huang, L., Kaksonen, M., Ahima, R., Hinkes, M.T., Barsh, G.S., Rauvale, H. and Bernfield, M. (2001) Cell, 106, 105-116.
71. Kamitani, W., Ono, E., Yoshino, S., Kobayashi, T., Taharaguchi, S., Lee, B.J., Yamashita, M., Kobayashi, T., Okamoto, M., Taniyama, H., Tomonaga, K. and Ikuta, K. (2003) Proc. Natl. Acad. Sci. USA, 100, 8969-8974.
72. Tomonaga, K. (2004) Trends Mol. Med., 10, 71-77.
73. Zhang, G., Kobayashi, T., Kamitani, W., Komoto, S., Yamashita, M., Baba, S., Yanai, H., Ikuta, K. and Tomonaga, K. (2003) J. Virol., 77, 12243-12251.
74. Bierhaus, A., Humpert, P.M., Morcos, M., Wendt, T., Chavakis, T., Arnold, B., Stern, D.M. and Nawroth, P.P. (2005) J. Mol. Med., 83, 876-886.
75. Wautier, J.L. and Schmidt, A.M. (2004) Circ. Res., 95, 233-238.
76. Naka, Y., Bucciarelli, L.G., Wendt, T., Lee, L., Rong, L.L., Ramasamy, R., Yan, S.F. and Schmidt, A.M. (2004) Arterioscler. Thromb. Vasc. Biol., 24, 1342-1349.
77. Hofmann, M.A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., Neurath, M.F., Slattery, T., Beach, D., McClary, J., Nagashima, M., Morser, J., Stern, D. and Schmidt, A.M. (1999) Cell, 97, 889-901.
78. Yang, H., Ochani, M., Li, J., Qiang, X., Tanovic, M., Harris, H.E., Susarla, S.M., Ulloa, L., Wang, H., DiRaimo, R., Czura, C.J., Wang, H., Roth, J., Warren, H.S., Fink, M.P., Fenton, M.J., Andersson, U. and Tracey, K.J. (2004) Proc. Natl. Acad. Sci. USA, 101, 296-301.
79. Yang, R., Harada, T., Mollen, K.P., Prince, J.M., Levy, R.M., Englert, J.A., Gallowitsch-Puerta, M., Yang, L., Yang, H., Tracey, K.J., Harbrecht, B.G., Billiar, T.R. and Fink, M.P. (2006) Mol. Med., 12, 105-114.
80. Raman, K.G., Sappington, P.L., Yang, R., Levy, R.M., Prince, J.M., Liu, S., Watkins, S.K., Schmidt, A.M., Billiar, T.R. and Fink, M.P. (2006) Am. J. Physiol. Gastrointest Liver Physiol., 291, G556-G565.
81. Fan, J., Li, Y., Levy, R.M., Fan, J.J., Hackam, D.J., Vodovotz, Y., Yang, H., Tracey, K.J., Billiar, T.R. and Wilson, M.A. (2007) J. Immunol., 178, 6573-6580.
82. Tsung, A., Zheng, N., Jeyabalan, G., Izuishi, K., Klune, J.R., Geller, D.A., Lotze, M.T., Lu, L. and Billiar, T.R. (2007) J. Leukoc. Biol., 81, 119-128.
83. Hatada, T., Wada, H., Nobori, T., Okabayashi, K., Maruyama, K., Abe, Y., Uemoto, S., Yamada, S. and Maruyama, I. (2005) Thromb. Haemost., 94, 975-979.
84. Ito, T., Kawahara, K., Nakamura, T., Yamada, S., Nakamura, T., Abeyama, K., Hashiguchi, T. and Maruyama, I. (2007) J. Thromb. Haemost., 5, 109-116.
85. Rouhiainen, A., Imai, S., Rauvala, H. and Parkkinen, J. (2000). Thromb Haemost., 84, 1087-1094.
86. Uesugi, H., Ozaki, S., Sobajima, J., Osakada, F., Shirakawa, H., Yoshida, M. and Nakao, K. (1998) J. Rheumatol., 25, 703-709.
87. Pullerits, R., Bokarewa, M., Dahlberg, L. and Tarkowski, A. (2007) Rheumatology, 46, 1367-1371.
88. Kokkola, R., Sundberg, E., Ulfgren, A.K., Palmblad, K., Li, J., Wang, H., Ulloa, L., Yang, H., Yan, X.J., Furie, R., Chiorazzi, N., Tracey, K.J., Andersson, U. and Harris, H.E. (2002) Arthritis Rheum., 46, 2598-2603.
89. Andersson, U. and Erlandsson-Harris, H. (2004) J. Intern. Med., 255, 344-350.
90. Andersson, U., Wang, H., Palmblad, K., Aveberger, A.-C., Bloom, O., Erlandsson-Harris, H., Janson, A., Kokkola, R., Yang, H. and Tracey, K.J. (2000) J. Exp. Med., 192, 565-570.
91. Scaffidi, P., Misteli, T. and Bianchi, M.E. (2002) Nature, 418, 191-195.
92. Chen, C.J., Kono, H., Golenbock, D., Reed, G., Akira, S. and Rock, K.L. (2007) Nat. Med., 13, 851-856.
93. Bell, C.W, Jiang, W., Reich, C.F. and Pisetsky, D.S. (2006) Am. J. Physiol. Cell Physiol., 291, C1318-1325.
94. Messmer, D., Yang, H., Telusma, G., Knoll, F., Li, J., Messmer, B., Tracey, K.J. and Chiorazzi, N. (2004) J. Immunol., 173, 307-313.
95. Semino, C., Angelini, G., Poggi, A. and Rubartelli, A. (2005) Blood, 106, 609-616.
96. Dumitriu, I.E., Baruah, P., Manfredi, A.A., Bianchi, M.E. and Rovere-Querini, P. (2005) Trends Immunol., 26, 381-387.
97. Dumitriu, I.E., Bianchi, M.E., Bacci, M., Manfredi, A.A. and Rovere-Querini, P. (2007) J. Leukoc. Biol., 81, 84-91.
98. Yang, D., Chen, C., Yang, H., Tracey, K.J., Bustin, M. and Oppenheim, J.J. (2007) J. Leukoc. Biol., 81, 59-66.
99. Götte, M. (2003) FASEB J., 17, 575-591.
100. Fages, C.,, Nolo, R., Huttunen, H.J., Eskelinen, E.-L. and Rauvala, H. (2000) J. Cell Sci., 113, 611-620.
101. Parkkinen, J. and Rauvala, H. (1991) J. Biol. Chem., 266, 16730-16735.
102. Ellerman, J.E., Brown, C.K., de Vera, M., Zeh, H.J., Billiar, T., Rubartelli, A. and Lotze, M.T. (2007) Clin. Cancer Res., 13, 2836-2848.
103. Schlueter, C., Weber, H., Meyer, B., Rogalla, P., Roser, K., Hauke, S.. and Bullerdiek, J. (2005) Am. J. Pathol., 166, 1259-1263.
104. van Beijnum, J.R., Dings, R.P., van der Linden, E., Zwaans, B.M.M., Ramaekers, F.C.S., Mayo, K.H. and Griffioen, A.W. (2006) Blood, 108, 2339-2348.
105. Alexopoulou, A.N., Multhaupt, H.A. and Couchman, J.R. (2007) Int. J. Biochem. Cell Biol., 39, 505-528.
106. Kuniyasu, H., Chihara, Y. and Takahashi, T. (2003) Oncol. Rep., 10, 445-448.
107. Kuniyasu, H., Sasaki, T., Sasahira, T., Ohmori, H. and Takahashi, T. (2004) Pathobiology, 71, 129-136.
108. Kuniyasu, H., Yano, S., Sasaki, T., Sasahira, T., Sone, S. and Ohmori, H. (2005) Am. J. Pathol., 166, 751-760.
109. Brezniceanu, M.L., Volp, K., Bosser, S., Solbach, C., Lichter, P., Joos, S. and Zornig, M. (2003) FASEB J., 17, 1295-1297.
110. Alexandrova, E.A. and Beltchev, B.G. (1987) Biochim. Biophys. Acta, 915, 399-405.
111. Wahamaa, H., Vallerskog, T., Qin, S., Lunderius, C., LaRosa, G., Andersson, U. and Harris, H.E. (2007) J. Leukoc. Biol., 81, 129-136.
112. Komblit, B., Munthe-Fog, L., Petersen, S.L., Madsen, H.O., Vindelov, L. and Garred, P. (2007) Tissue Antigens., 70, 151-156.
113. Laakso, M., Tuupanen, S., Karhu, A., Lehtonen, R., Aaltonen, L.A. and Hautaniemi, S. (2007) Bioinformatics, 23, 1952-1961.
114. Kalinina, N., Agrotis, A., Antropova, Y., DiVitto, G., Kanellakis, P., Kostolias, G., Ilyinskaya, O., Tararak, E. and Bobik, A. (2004) Arterioscler. Thromb. Vasc. Biol., 24, 2320-2325
115. Porto, A., Palumbo, R., Pieroni, M., Aprigliano, G., Chiesa, R., Sanvito, F., Maseri, A. and Bianchi, M.E. (2006) FASEB J., 20, 2565-2566.
116. Inoue, K., Kawahara, K.-I., Biswas, K.K., Ando, K., Mitsudo, K., Nobuyoshi, M. and Maruyama, I. Cardiovasc. Pathol., in press.
117. Tracey, K.J. (2007) J. Clin. Invest., 117, 289-296.
118. Wang, H., Yu, M., Ochani, M., Amella, C.A., Tanovic, M., Susarla, S., Li, J.H., Wang, H., Yang, H., Ulloa, L., Al-Abed, Y., Czura, C.J. and Tracey, K.J. (2003) Nature, 421, 384-388.
119. Wang, H., Liao, H., Ochani, M., Justiniani, M., Lin, X., Yang, L., Al-Abed, Y., Wang, H., Metz, C., Miller, E.J., Tracey, K.J. and Ulloa, L. (2004) Nat. Med., 10, 1216-1221.
120. Saeed, R.W., Varma, S., Peng-Nemeroff, T., Sherry, B., Balakhaneh, D., Huston, J., Tracey, K.J., Al-Abed, Y. and Metz, C.N. (2005) J. Exp. Med., 201, 1113-1123.
121. Vakkila, J. and Lotze, M.T. (2004) Nat. Rev. Immunol., 4, 641-648.
122. Sorci, G., Riuzzi, F., Arcuri, C., Giambanco, I. and Donato, R. (20D4) Mol. Cell Biol., 24, 4880-4894.
123. Riuzzi, F., Sorci, G. and Donato, R. (2007) Am. J. Pathol., 171, 947-961.
124. Palumbo, R., Sampaolesi, M., De Marchis, F., Tonlorenzi, R., Colombetti, S., Mondino, A., Cossu, G. and Bianchi, M.E. (2004) J. Cell Biol., 164, 441-449.
125. Limana, F., Germani, A., Zacheo, A., Kajstura, J., Di Carlo, A., Borsellino, G., Leoni, O., Palumbo, R., Battistini, L., Rastaldo, R., Muller, S., Pompilio, G., Anversa, P., Bianchi, M.E. and Capogrossi, M.C. (2005) Circ. Res., 97, e73-83.
126. Germani, A., Limana, F. and Capogrossi, M.C. (2007) J. Leukoc. Biol., 81, 41-45.