The genetic variation of the human HMGB1 gene

Tissue Antigens

Volumn 70, Issue 2, 2007, Pages 151-156

  Kornblit, B ^a,b   Munthe Fog, L ^a   Petersen, S L ^a   Madsen, H O ^a   Vindelov L ^a   Garred, P ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Rigshospitalet   (Denmark)

Author keywords

Cytokines; HMGB1; Inflammation; Innate immunity; Polymorphisms

Indexed keywords

DNA BINDING PROTEIN;

ARTICLE; BLOOD DONOR; DNA POLYMORPHISM; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

HMGB1 PROTEIN; HUMANS; VARIATION (GENETICS);

EID: 34347372210     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2007.00854.x     Document Type: Article

References (51)

1. Javaherian K, Liu JF, Wang JC. Nonhistone proteins HMG1 and HMG2 change the DNA helical structure. Science 1978 : 199 : 1345 6.
2. Bustin M, Hopkins RB, Isenberg I. Immunological relatedness of high mobility group chromosomal proteins from calf thymus. J Biol Chem 1978 : 253 : 1694 9.
3. Baker C, Isenberg I, Goodwin GH, Johns EW. Physical studies of the nonhistone chromosomal proteins HMG-U and HMG-2. Biochemistry 1976 : 15 : 1645 9.
4. Bianchi ME, Beltrame M, Paonessa G. Specific recognition of cruciform DNA by nuclear protein HMG1. Science 1989 : 243 : 1056 9.
5. West KL, Castellini MA, Duncan MK, Bustin M. Chromosomal proteins HMGN3a and HMGN3b regulate the expression of glycine transporter 1. Mol Cell Biol 2004 : 24 : 3747 56.
6. Park JS, Arcaroli J, Yum HK et al. Activation of gene expression in human neutrophils by high mobility group box 1 protein. Am J Physiol Cell Physiol 2003 : 284 : C870 9.
7. Stros M, Ozaki T, Bacikova A, Kageyama H, Nakagawara A. HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoter. J Biol Chem 2002 : 277 : 7157 64.
8. Calogero S, Grassi F, Aguzzi A et al. The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice. Nat Genet 1999 : 22 : 276 80.
9. Wang H, Bloom O, Zhang M et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999 : 285 : 248 51.
10. Yang H, Ochani M, Li J et al. Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci 2004 : 101 : 296 301.
11. Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002 : 418 : 191 5.
12. Hori O, Brett J, Slattery T et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. J Biol Chem 1995 : 270 : 25752 61.
13. Park JS, Svetkauskaite D, He Q et al. Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004 : 279 : 7370 7.
14. Rovere-Querini P, Capobianco A, Scaffidi P et al. HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep 2004 : 5 : 825 30.
15. Bonaldi T, Talamo F, Scaffidi P et al. Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion. EMBO J 2003 : 22 : 5551 60.
16. Taniguchi N, Kawahara K, Yone K et al. High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum 2003 : 48 : 971 81.
17. Kokkola R, Li J, Sundberg E et al. Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity. Arthritis Rheum 2003 : 48 : 2052 8.
18. Ombrellino M, Wang H, Ajemian MS et al. Increased serum concentrations of high-mobility-group protein 1 in haemorrhagic shock. Lancet 1999 : 354 : 1446 7.
19. Goldstein RS, Gallowitsch-Puerta M, Yang L et al. Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia. Shock 2006 : 25 : 571 4.
20. Ueno H, Matsuda T, Hashimoto S et al. Contributions of high mobility group box protein in experimental and clinical acute lung injury. Am J Respir Crit Care Med 2004 : 170 : 1310 6.
21. Flohr AM, Rogalla P, Meiboom M et al. Variation of HMGB1 expression in breast cancer. Anticancer Res 2001 : 21 : 3881 5.
22. Choi YR, Kim H, Kang HJ et al. Overexpression of high mobility group box 1 in gastrointestinal stromal tumors with KIT mutation. Cancer Res 2003 : 63 : 2188 93.
23. Kuniyasu H, Oue N, Wakikawa A et al. Expression of receptors for advanced glycation end-products (RAGE) is closely associated with the invasive and metastatic activity of gastric cancer. J Pathol 2002 : 196 : 163 70.
24. Kuniyasu H, Chihara Y, Takahashi T. Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer. Oncol Rep 2003 : 10 : 445 8.
25. Huttunen HJ, Fages C, Kuja-Panula J, Ridley AJ, Rauvala H. Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis. Cancer Res 2002 : 62 : 4805 11.
26. Nestl A, Von Stein OD, Zatloukal K et al. Gene expression patterns associated with the metastatic phenotype in rodent and human tumors. Cancer Res 2001 : 61 : 1569 77.
27. Muller S, Ronfani L, Bianchi ME. Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function. J Intern Med 2004 : 255 : 332 43.
28. Lee KB, Thomas JO. The effect of the acidic tail on the DNA-binding properties of the HMG1,2 class of proteins: insights from tail switching and tail removal. J Mol Biol 2000 : 304 : 135 49.
29. Ferrari S, Finelli P, Rocchi M, Bianchi ME. The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13. Genomics 1996 : 35 : 367 71.
30. Bianchi ME. The HMG box domain. In : Lilley DMJ, ed. DNA-Protein: Structural Interactions. Oxford : Oxford University Press, 1995, 177 200.
31. Bustin M, Lehn DA, Landsman D. Structural features of the HMG chromosomal proteins and their genes. Biochim Biophys Acta 1990 : 1049 : 231 43.
32. Wen L, Huang JK, Johnson BH, Reeck GR. A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1. Nucleic Acids Res 1989 : 17 : 1197 214.
33. Agresti A, Bianchi ME. HMGB proteins and gene expression. Curr Opin Genet Dev 2003 : 13 : 170 8.
34. Reeck GR, Isackson PJ, Teller DC. Domain structure in high molecular weight high mobility group nonhistone chromatin proteins. Nature 1982 : 300 : 76 8.
35. Cary PD, Turner CH, Leung I, Mayes E, Crane-Robinson C. Conformation and domain structure of the non-histone chromosomal proteins HMG 1 and 2. Domain interactions. Eur J Biochem 1984 : 143 : 323 30.
36. Hollegaard MV, Bidwell JL. Cytokine gene polymorphism in human disease: on-line databases. Genes Immun 2006 : 7 (Suppl 3 269 76.
37. Sherry ST, Ward MH, Kholodov M et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res 2001 : 29 : 308 11.
38. Hall TA. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT [computer program]. Version 7.0.5.3. Nucleic Acids Symp Ser 1999 : 41 : 95 8.
39. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Wheeler DL. GenBank. Nucleic Acids Res 2006 : 34 (Suppl 1 D16 D20.
40. Quandt K, Frech K, Karas H, Wingender E, Werner T. MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 1995 : 23 : 4878 84.
41. Borrmann L, Kim I, Schultheiss D, Rogalla P, Bullerdiek J. Regulation of the expression of HMG1, a co-activator of the estrogen receptor. Anticancer Res 2001 : 21 (1A 301 5.
42. Lum HK, Lee KL. The human HMGB1 promoter is modulated by a silencer and an enhancer-containing intron. Biochim Biophys Acta 2001 : 1520 : 79 84.
43. Mantovani R. A survey of 178 NF-Y binding CCAAT boxes. Nucleic Acids Res 1998 : 26 : 1135 43.
44. Mailly F, Berube G, Harada R, Mao PL, Phillips S, Nepveu A. The human Cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy. Mol Cell Biol 1996 : 16 : 5346 57.
45. Nepveu A. Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development. Gene 2001 : 270 : 1 15.
46. Biedenkapp H, Borgmeyer U, Sippel AE, Klempnauer KH. Viral myb oncogene encodes a sequence-specific DNA-binding activity. Nature 1988 : 335 : 835 7.
47. Weston K. Myb proteins in life, death and differentiation. Curr Opin Genet Dev 1998 : 8 : 76 81.
48. Hernandez-Munain C, Krangel MS. Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. Mol Cell Biol 1994 : 14 : 473 83.
49. Chayka O, Kintscher J, Braas D, Klempnauer KH. v-Myb mediates cooperation of a cell-specific enhancer with the mim-1 promoter. Mol Cell Biol 2005 : 25 : 499 511.
50. Hebsgaard SM, Korning PG, Tolstrup N, Engelbrecht J, Rouze P, Brunak S. Splice site prediction in Arabidopsis thaliana pre-mRNA by combining local and global sequence information. Nucleic Acids Res 1996 : 24 : 3439 52.
51. Brunak S, Engelbrecht J, Knudsen S. Prediction of human mRNA donor and acceptor sites from the DNA sequence. J Mol Biol 1991 : 220 : 49 65.