Borna Disease Virus Phosphoprotein Represses p53-Mediated Transcriptional Activity by Interference with HMGB1

Journal of Virology

Volumn 77, Issue 22, 2003, Pages 12243-12251

  Zhang, Guoqi ^a   Kobayashi, Takeshi ^a   Kamitani, Wataru ^a   Komoto, Satoshi ^a   Yamashita, Makiko ^a   Baba, Satoko ^a   Yanai, Hideyuki ^a   Ikuta, Kazuyoshi ^a   Tomonaga, Keizo ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; HIGH MOBILITY GROUP B1 PROTEIN; PROTEIN P21; PROTEIN P53; RECOMBINANT PROTEIN;

ANIMAL DISEASE; ARTICLE; BORNA DISEASE; BORNA DISEASE VIRUS; GENETIC TRANSCRIPTION; NERVE FIBER GROWTH; NEUROLOGIC DISEASE; NONHUMAN; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TUMOR SUPPRESSOR GENE;

ANIMALS; BINDING, COMPETITIVE; BORNA DISEASE VIRUS; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA; HMGB1 PROTEIN; RATS; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53; VIRAL PROTEINS;

EID: 0242363230     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.22.12243-12251.2003     Document Type: Article

References (48)

1. Aidinis, V., T. Bonaldi, M. Beltrame, S. Santagata, M. E. Bianchi, and E. Spanopoulou. 1999. The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2. Mol. Cell. Biol. 19:6532-6542.
2. Barber, G. N. 2001. Host defense, viruses and apoptosis. Cell Death Differ. 8:113-126.
3. Boonyaratanakornkit, V., V. Melvin, P. Prendergast, M. Altmann, L. Ronfani, M. E. Bianchi, L. Taraseviciene, S. K. Nordeen, E. A. Allegretto, and D. P. Edwards. 1998. High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells. Mol. Cell. Biol. 18:4471-4487.
4. Bustin, M. 1999. Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol. Cell. Biol. 19:5237-5246.
5. Butteroni, C., M. De Felici, H. R. Scholer, and M. Pesce. 2000. Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins. J. Mol. Biol. 304:529-540.
6. Carbone, K. M. 2001. Borna disease virus and human disease. Clin. Microbiol. Rev. 14:513-527.
7. Costello, E., P. Saudan, E. Winocour, L. Pizer, and P. Beard. 1997. High mobility group chromosomal protein 1 binds to the adeno-associated virus replication protein (Rep) and promotes Rep-mediated site-specific cleavage of DNA, ATPase activity and transcriptional repression. EMBO J. 16:5943-5954.
8. Cubitt, B., C. Oldstone, and J. C. de la Torre. 1994. Sequence and genome organization of Borna disease virus. J. Virol. 68:1382-1396.
9. De Laurenzi, V., and G. Melino. 2000. Evolution of functions within the p53/p63/p73 family. Ann. N. Y. Acad. Sci. 926:90-100.
10. Dintilhac, A., and J. Bernues. 2002. HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences. J. Biol. Chem. 277:7021-7028.
11. El-Deiry, W. S. 1998. p21/p53, cellular growth control and genomic integrity. Curr. Top. Microbiol. Immunol. 227:121-137.
12. El-Deiry, W. S. 1998. Regulation of p53 downstream genes. Semin. Cancer Biol. 8:345-357.
13. Fages, C., R. Nolo, H. J. Huttunen, E. Eskelinen, and H. Rauvala. 2000. Regulation of cell migration by amphoterin. J. Cell Sci. 113:611-620.
14. Fazakerley, J. K., and T. E. Allsopp. 2001. Programmed cell death in virus infections of the nervous system. Curr. Top. Microbiol. Immunol. 253:95-119.
15. Fortin, A., S. P. Cregan, J. G. MacLaurin, N. Kushwaha, E. S. Hickman, C. S. Thompson, A. Hakim, P. R. Albert, F. Cecconi, K. Helin, D. S. Park, and R. S. Slack. 2001. APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. J. Cell Biol. 155:207-216.
16. Friborg, J., Jr., W. Kong, M. O. Hottiger, and G. J. Nabel. 1999. p53 inhibition by the LANA protein of KSHV protects against cell death. Nature 402:889-894.
17. Ge, H., and R. G. Roeder. 1994. The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. J. Biol. Chem. 269:17136-17140.
18. Hardman, C. H., R. W. Broadhurst, A. R. Raine, K. D. Grasser, J. O. Thomas, and E. D. Laue. 1995. Structure of the A-domain of HMG1 and its interaction with DNA as studied by heteronuclear three- and four-dimensional NMR spectroscopy. Biochemistry 34:16596-16607.
19. Hausmann, J., W. Hallensleben, J. C. de la Torre, A. Pagenstecher, C. Zimmermann, H. Pircher, and P. Staeheli. 1999. T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein. Proc. Natl. Acad. Sci. USA 96:9769-9774.
20. Hornig, M., H. Weissenbock, N. Horscroft, and W. I. Lipkin. 1999. An infection-based model of neurodevelopmental damage. Proc. Natl. Acad. Sci. USA 96:12102-12107.
21. Hornig, M., T. Briese, and W. I. Lipkin. 2001. Bornavirus tropism and targeted pathogenesis: virus-host interactions in a neurodevelopmental model. Adv. Virus Res. 56:557-582.
22. Hornig, M., M. Solbrig, N. Horscroft, H. Weissenbock, and W. I. Lipkin. 2001. Borna disease virus infection of adult and neonatal rats: models for neuropsychiatric disease. Curr. Top. Microbiol. Immunol. 253:157-177.
23. Huttunen, H. J., C. Fages, and H. Rauvala. 1999. Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-KB require the cytoplasmic domain of the receptor but different downstream signaling pathways, J. Biol. Chem. 274:19919-19924.
24. Huttunen, H. J., J. Kuja-Panula, G. Sorci, A. L. Agneletti, R. Donato, and H. Rauvala. 2000. Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation. J. Biol. Chem. 275:40096-40105.
25. Ikuta, K., M. S. Ibrahim, T. Kobayashi, and K. Tomonaga. 2002. Borna disease virus and infection in humans. Front. Biosci. 7:D470-D495.
26. Imamura, T., H. Izumi, G. Nagatani, T. Ise, M. Nomoto, Y. Iwamoto, and K. Kohno. 2001. Interaction with p53 enhances binding of cisplatin-modified DNA by high mobility group 1 protein. J. Biol. Chem. 276:7534-7540.
27. Jayaraman, L., K. G. Murthy, C. Zhu, T. Curran, S. Xanthoudakis, and C. Prives. 1997. Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev. 11:558-570.
28. Jayaraman, L., N. C. Moorthy, K. G. Murthy, J. L. Manley, M. Bustin, and C. Prives. 1998. High mobility group protein-1 (HMG-1) is a unique activator of p53. Genes Dev. 12:462-472.
29. Jordan, I., and W. I. Lipkin. 2001. Borna disease virus. Rev. Med. Virol. 11:37-57.
30. Kamitani, W., Y. Shoya, T. Kobayashi, M. Watanabe, B. J. Lee, G. Zhang, K. Tomonaga, and K. Ikuta. 2001. Borna disease virus phosphoprotein binds a neurite outgrowth factor, amphoterin/HMG-1. J. Virol. 75:8742-8751.
31. Ludwig, H., and L. Bode. 2000. Borna disease virus: new aspects on infection, disease, diagnosis and epidemiology. Rev. Sci. Technol. 19:259-288.
32. Miyashita, T., and J. C. Reed. 1995. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299.
33. Nakamura, Y., H. Takahashi, Y. Shoya, T. Nakaya, M. Watanabe, K. Tomonaga, K. Iwahashi, K. Ameno, N. Momiyama, H. Taniyama, T. Sata, T. Kurata, J. C. de la Torre, and K. Ikuta. 2000. Isolation of Borna disease virus from human brain tissue. J. Virol. 74:4601-4611.
34. Osaki, S., Y. Nakanishi, K. Takayama, X. H. Pei, H. Ueno, and N. Hara. 2000. Alteration of drug chemosensitivity caused by the adenovirus-mediated transfer of the wild-type p53 gene in human lung cancer cells. Cancer Gene Ther. 7:300-307.
35. Pyrzynska, B., M. Serrano, A. C. Martinez, and B. Kaminska. 2002. Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A. J. Biol. Chem. 277:14102-14108.
36. Rauvala, H., H. J. Huttunen, C. Fages, M. Kaksonen, T. Kinnunen, S. Imai, E. Raulo, and I. Kilpelainen. 2000. Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility. Matrix Biol. 19:377-387.
37. Rott, R., and H. Becht. 1995. Natural and experimental Borna disease in animals. Curr. Top. Microbiol. Immunol. 190:17-30.
38. Schwemmle, M., C. Jehle, S. Formella, and P. Staeheli. 1999. Sequence similarities between human Bornavirus isolates and laboratory strains question human origin. Lancet 354:1973-1974.
39. + T cells and perforin mRNA. J. Virol. 71:2400-2407.
40. Staeheli, P., C. Sauder, J. Hausmann, F. Ehrensperger, and M. Schwemmle. 2000. Epidemiology of Borna disease virus. J. Gen. Virol. 81:2123-2135.
41. Stitz, L., T. Bilzer, and O. Planz. 2002. The immunopathogenesis of Borna disease virus infection. Front. Biosci. 7:D541-D555.
42. Stros, M., T. Ozaki, A. Bacikova, H. Kageyama, and A. Nakagawara. 2002. HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoter. J. Biol. Chem. 277:7157-7164.
43. Tomonaga, K., T. Kobayashi, and K. Ikuta. 2002. Molecular and cellular biology of Borna disease virus infection. Microbes Infect. 4:491-500.
44. Waltrip, R. W., II, R. W. Buchanan, W. T. Carpenter, Jr., B. Kirkpatrick, A. Summerfelt, A. Breier, S. A. Rubin, and K. M. Carbone. 1997. Borna disease virus antibodies and the deficit syndrome of schizophrenia. Schizophr. Res. 23:253-257.
45. Weir, H. M., P. J. Kraulis, C. S. Hill, A. R. Raine, E. D. Laue, and J. O. Thomas. 1993. Structure of the HMG box motif in the B-domain of HMG1. EMBO J. 12:1311-1319.
46. Weissenbock, H., M. Hornig, W. F. Hickey, and W. I. Lipkin. 2000. Microglial activation and neuronal apoptosis in Bornavirus infected neonatal Lewis rats. Brain Pathol. 10:260-272.
47. Zappavigna, V., L. Falciola, M. Helmer-Citterich, F. Mavilio, and M. E. Bianchi. 1996. HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation. EMBO J. 15:4981-4991.
48. Zwilling, S., H. Konig, and T. Wirth. 1995. High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. EMBO J. 14:1198-1208.