Inhibition of delayed rectifier potassium channels and induction of arrhythmia: A novel effect of celecoxib and the mechanism underlying it

Journal of Biological Chemistry

Volumn 283, Issue 3, 2008, Pages 1518-1524

  Frolov, Roman V ^a   Berim, Ilya G ^a   Singh, Satpal ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; MUSCULOSKELETAL SYSTEM; POTASSIUM;

MUSCULOSKELETAL COMPLAINTS;

ENZYME INHIBITION;

CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DELAYED RECTIFIER POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARDIOTOXICITY; CELL CULTURE; CONTROLLED STUDY; DROSOPHILA; DRUG EFFECT; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG MECHANISM; HEART ARRHYTHMIA; HEART MUSCLE CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ARRHYTHMIAS, CARDIAC; CELLS, CULTURED; CYCLOOXYGENASE INHIBITORS; DELAYED RECTIFIER POTASSIUM CHANNELS; DROSOPHILA MELANOGASTER; HEART RATE; HUMANS; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; PYRAZOLES; RATS; SHAB POTASSIUM CHANNELS; SULFONAMIDES;

RATTUS;

EID: 38349110209     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708100200     Document Type: Article

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