Volociximab, a chimeric integrin alpha5beta1 antibody, inhibits the growth of VX2 tumors in rabbits

Investigational New Drugs

Volumn 26, Issue 1, 2008, Pages 7-12

  Bhaskar, Vinay ^a   Fox, Melvin ^a   Breinberg, Danna ^a   Wong, Melanie H L ^a   Wales, Pauline E ^a   Rhodes, Susan ^a   DuBridge, Robert B ^a   Ramakrishnan, Vanitha ^a  

^a PDL BioPharma Inc   (United States)

Author keywords

Alpha5; Angiogenesis; Beta1; Integrin; Volociximab; VX2 tumor

Indexed keywords

CHIMERIC ANTIBODY; INTEGRIN; VERY LATE ACTIVATION ANTIGEN 5; VOLOCIXIMAB;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; RABBIT; TUMOR GROWTH;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CLINICAL TRIALS, PHASE III AS TOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRONECTINS; HUMANS; IMMUNOCHEMISTRY; INJECTIONS, INTRAVENOUS; INTEGRIN ALPHA5BETA1; MICE; NEOPLASMS, EXPERIMENTAL; PROTEIN BINDING; RABBITS; SPECIES SPECIFICITY; SURFACE PLASMON RESONANCE; TUMOR BURDEN;

EID: 38149086091     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-007-9078-z     Document Type: Article

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