The small α5β1 integrin antagonist, SJ749, reduces proliferation and clonogenicity of human astrocytoma cells

Cancer Research

Volumn 66, Issue 12, 2006, Pages 6002-6007

  Maglott, Anne ^a   Bartik, Petr ^a   Cosgun, Sedat ^b   Klotz, Philippe ^b   Rondé, Philippe ^a   Fuhrmann, Guy ^a   Takeda, Kenneth ^a   Martin, Sophie ^a   Dontenwill, Monique ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Laboratoire de Pharmacochimie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; FIBRONECTIN; S 2 [(2,4,6 TRIMETHYLPHENYL) SULFONYL] AMINO 3 [7 BENZYLOXYCARBONYL 8 (2 PYRIDINYLAMINOMETHYL) 1 OXA 2,7 DIAZASPIRO (4,4) NON 2 EN 3 YL]CARBONYLAMINO]PROPIONIC ACID; SJ 749; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; PROPIONIC ACID DERIVATIVE; PYRIDINE DERIVATIVE; SJ749; SPIRO COMPOUND;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ASTROCYTOMA CELL; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CLONOGENESIS; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ASTROCYTOMA; BIOSYNTHESIS; BRAIN TUMOR; CELL ADHESION; CELL GROWTH; DOSE RESPONSE; DRUG ANTAGONISM; DRUG SCREENING; ENZYME SPECIFICITY; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; TUMOR CELL LINE;

ASTROCYTOMA; BRAIN NEOPLASMS; CELL ADHESION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTEGRIN ALPHA5BETA1; PROPIONIC ACIDS; PYRIDINES; SPHEROIDS, CELLULAR; SPIRO COMPOUNDS; SUBSTRATE SPECIFICITY; TUMOR STEM CELL ASSAY;

EID: 33745728177     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-4105     Document Type: Article

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