Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication

Antiviral Research

Volumn 77, Issue 2, 2008, Pages 95-107

  Patel, Deendayal ^a   Opriessnig, Tanja ^c   Stein, David A ^b   Halbur, Patrick G ^c   Meng, Xiang Jin ^d   Iversen, Patrick L ^b   Zhang, Yan Jin ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b AVI BIOPHARMA INC   (United States)

^c IOWA STATE UNIVERSITY   (United States)

^d CENTER FOR MOLECULAR MEDICINE AND INFECTIOUS DISEASES   (United States)

Author keywords

Antisense; Antiviral; Morpholino; Porcine reproductive and respiratory syndrome virus; PRRSV; PRRSV RNA

Indexed keywords

LUCIFERASE; MORPHOLINE DERIVATIVE; OLIGOMER; PEPTIDE CONJUGATED PHOSPHORODIAMIDATE MORPHOLINO OLIGOMER; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ARTERIVIRUS; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG STRUCTURE; IMMUNOFLUORESCENCE TEST; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; STATISTICAL ANALYSIS; SWINE DISEASE; VIRUS GENOME; VIRUS INHIBITION;

ANIMALS; ANTIVIRAL AGENTS; BASE SEQUENCE; CELL LINE; CELL SURVIVAL; CELL-FREE SYSTEM; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENES, REPORTER; HUMANS; MACROPHAGES, ALVEOLAR; MICE; MORPHOLINES; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDES; POLYMERASE CHAIN REACTION; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; PROTEIN BIOSYNTHESIS; RNA, VIRAL; SEQUENCE ALIGNMENT; SWINE; VIRUS REPLICATION;

PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SUIDAE; SUS;

EID: 38149025656     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2007.09.002     Document Type: Article

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