Monoclonal antibodies against conformationally dependent epitopes on porcine reproductive and respiratory syndrome virus

Veterinary Microbiology

Volumn 63, Issue 2-4, 1998, Pages 125-136

  Zhang, Yanjin ^a   Sharma, Rameshwer D ^a   Paul, Prem S ^a  

^a Coll Vet M   (United States)

Author keywords

Antigenic variations; Monoclonal antibodies; Pig viruses; Porcine reproductive and respiratory syndrome virus (PRRSV)

Indexed keywords

CELL EXTRACT; DETERGENT; EPITOPE; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; VIRUS ANTIGEN;

ANIMAL CELL; ANTIGENIC VARIATION; ARTERIVIRUS; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNIZATION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INSECT; MOUSE; NONHUMAN; SWINE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, VIRAL; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; MICE; OPEN READING FRAMES; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY;

EID: 0031727137     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1135(98)00231-4     Document Type: Article

References (38)

1. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., Struhl, K., 1992. Short Protocols in Molecular Biology, 2nd ed. Greene Publishing Associate and Wiley, New York.
2. Balasuriya U.B.R., Maclachlan N.J., De Vries A.A.F., Rossitto P.V., Rottier P.J.M. Identification of a neutralizing site in the major envelope glycoprotein (Gl) of equine arteritis virus. Virology. 207:1995;518-527.
3. Benfield D.A., Nelson E., Collins J.E., Harris I., Goyal S.M., Tobison D., Christianson W.T., Morrison R.B., Gorcyca D., Chladek D. Characterization of swine infertility and respiratory syndrome (SIRS) virus (isolate ATCC VR-2332). J. Vet. Diag. Invest. 4:1992;127-133.
4. Bream G.L., Ohmstede C.A., Phelps P.C. Characterization of Human papillomavirus type 11 E1 and E2 proteins expressed in insect cells. J. Virol. 67:1993;2655-2663.
5. Brown, G., Ling, N.R., 1988. Murine monoclonal antibodies. In: Catty, D. (Ed.), Antibodies: A Practical Approach. IRL Press, Washington, DC, pp. 81-104.
6. Christianson W.T., Collins J.E., Benfield D.A., Harris I., Gorcyca D.E., Chladek D.W., Morrison R.B., Joo H.S. Experimental reproduction of swine infertility and respiratory syndrome in pregnant sows. Am. J. Vet. Res. 53:1992;485-488.
7. Conzelmann K.K., Vusser N., van Woensel P., Thiel J.-J. Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the Arterivirus group. Virology. 193:1993;329-339.
8. Dea S., Gagnon C.A., Mardassi H., Milane G. Antigenic variability among North American and European strains of porcine reproductive and respiratory syndrome virus as defined by monoclonal antibodies to the matrix protein. J. Clin. Microbiol. 34:1996;1488-1493.
9. Drew T.W., Meulenberg J.J.M., Sands J.J., Paton D.J. Production, characterization and reactivity of monoclonal antibodies to porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 76:1995;1361-1369.
10. Goyal S.M. Porcine reproductive and respiratory syndrome (review article). J. Vet. Diag. Invest. 5:1993;656-664.
11. Halbur P.G., Paul P.S., Frey Y.L., Landgraft J., Eernisse K., Meng X.-J., Lum M.A., Rathje J.A. Comparison of the pathogenicity of two U.S. porcine reproductive and respiratory syndrome virus isolates with the Lelystad virus. Vet. Pathol. 32:1995;648-660.
12. Halbur P.G., Paul P.S., Meng X.-J., Lum M.A., Rathje J.A. Comparative pathogenicity of nine U.S. porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a 5-week-old cesarean-derived-colostrum-deprived pig model. J. Vet. Diag. Invest. 8:1996;11-20.
13. Harlow, E.D., David, I., 1988. Antibodies: A laboratory manual. Cold Spring Harbor Laboratory, New York.
14. Hill, H., 1990. Overview and history of mystery swine disease (swine infertility and respiratory syndrome). Proceeding of Mystery Swine Disease Communication Meeting, Denver, CO, pp. 29-31.
15. Kapur V., Elam M.R., Pawlovich T.M., Murtaugh M.P. Genetic variation in porcine reproductive and respiratory syndrome virus isolates in the midwestern United States. J. Gen. Virol. 77:1996;1271-1276.
16. Mardassi H., Athanassious R., Mounir S., Dea S. Porcine reproductive and respiratory syndrome virus: Morphological, biochemical and serological characteristics of Quebec isolates associated with acute and chronic outbreaks of porcine reproductive and respiratory syndrome. Can. J. Vet. Res. 58:1994;55-64.
17. Mardassi H., Mounir S., Dea S. Molecular analysis of the ORFs 3 to 7 of porcine reproductive and respiratory syndrome virus Quebec reference strain. Arch. Virol. 140:1995;1405-1418.
18. Mardassi H., Mounir S., Dea S. Intercellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus. Virology. 221:1996;98-112.
19. Mecham J.O., Jochim M.M. Monoclonal antibodies to bluetongue virus define two neutralizing epitopes and a hemagglutinating epitope. Viral Immunol. 3(2):1990;161-170.
20. Meng X.-J., Paul P.S., Halbur P.G. Molecular cloning and nucleotide sequencing of the 3′-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 75:1994;1795-1801.
21. Meng, X.-J., Paul, P.S., Morozov, I., Halbur, P.G., 1995a. Sequence comparison of the open reading frames 2 to 5 of low and high virulence U.S. isolates of porcine reproductive and respiratory syndrome virus (PRRSV). J. Gen. Virol. 76, 3181-3188.
22. Meng, X.-J., Paul, P.S., Halbur, P.G., Lum, M.A., 1995b. Phylogenetic analysis of the putative M (ORF6) and N (ORF7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): Implication for the existence of two genotypes of PRRSV in the USA and Europe. Arch. Virol. 140, 745-755.
23. Meng, X.-J., Paul, P.S., Morozov, I., Halbur, P.G., 1996a. A nested set of six or seven subgenomic mRNAs is formed in cells infected with different isolates of porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 77, 1265-1270.
24. Meng, X.-J., Paul, P.S., Halbur, P.G., Lum, M.A., 1996b. Propagation of porcine reproductive and respiratory syndrome virus (PRRSV) in a continuous cell line and preliminary characterization of a high virulence U.S. isolate of PRRSV. J. Vet. Diag. Invest. 8, 374-381.
25. Meulenberg J.J.M., Hylst M.M., De Meijer E.J., Moonen P.L.M., Den besten A., De Kluyver E.P., Wensvoort G., Moormann R.J.M. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology. 192:1993;62-72.
26. Meulenberg J.J.M., Petersen-den besten A., De Kluyver E.P., Moormann R.J.M., Schaaper W.M.M., Wensvoort G. Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus. Virology. 206:1995;155-163.
27. Meulenberg J.J.M., van Nieuwstadt A.P., van Essen-zandbergen A., Langeveld J.P.M. Posttanslational processing and identification of a neutralizing domain of the GP4 protein encoded by ORF4 of Lelystad virus. J. Virol. 71:1997;6061-6067.
28. Morozov I., Meng X.-J., Paul P.S. Sequence analysis of the open reading frames (ORF) 2 to 4 of a U.S. isolate of porcine reproductive and respiratory syndrome virus (PRRSV). Arch. Virol. 140:1995;1313-1319.
29. Nelson E.A., Christopher-Hennings J., Drew T., Wensvoort G., Collins J.E., Benfield D.A. Differentiation of U.S. and European isolates of porcine reproductive and respiratory syndrome virus by monoclonal antibodies. J. Clin. Microbiol. 31:1993;3184-3189.
30. O'Reilly, D.R., Miller, I.K., Luckow, V.A., 1992. Baculovirus Expression Vectors: A Laboratory Manual, 2nd ed. WH Freeman and Company, New York.
31. Pfeffer S.R., Rothman J.E. Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Ann. Rev. Biochem. 56:1987;829-852.
32. Pizadeh B., Dea S. Monoclonal antibodies to the ORF5 product of porcine reproductive and respiratory syndrome virus define linear neutralizing determinants. J. Gen. Virol. 78:1997;1867-1873.
33. Plagemann P.G.W., Moennig V. Lactate dehydrogenase-elevating virus, equine arteritis virus and simian hemorrhagic fever virus, a new group of positive strand RNA virus. Adv. Virus Res. 41:1992;99-192.
34. Rodriguez M.J., Sarraseca J., Garcia J., Sanz A., Plana-Duran J., Casal J.I. Epitope mapping of the nucleocapsid protein of European and North American isolates of porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 78:1997;2269-2278.
35. Simkins, R.A., Saif, I.J., Weilnau, P.A., 1989. Epitope mapping and the detection of transmissible gastroenteritis viral proteins in cell culture using biotinylated monoclonal antibodies in a fixed-cell ELISA. Arch. Virol. 107 (3-4), 179-190.
36. van Nieuwstadt A.P., Meulenberg J.J.M., Essen-zandbergen A., Besten A.P., Bende R.J., Moonmann R.J.M., Wensvoort G. Proteins encoded by Open reading frames 3 and 4 of the genome of Lelystad virus (Arteriviridae) are structural proteins of the virion. J. Virol. 70(7):1996;4767-4772.
37. White J.R., Eaton B.T. Conformation of the VP2 protein of bluetongue virus (BTV) determines the involvement in virus neutralization of highly conserved epitopes within the BTV serogroup. J. Gen. Virol. 71:1990;1325-1332.
38. Wieczorek-krohmer M., Weiland F., Conzelmann K., Kohl D., Visser N., Van Woensel P., Thiel H.-J., Weiland E. Porcine reproductive and respiratory syndrome virus (PRRSV): Monoclonal antibodies detect common epitopes on two viral proteins of European and U.S. isolates. Vet. Microbiol. 51:1996;257-266.