Direct catalysis of lysine 48-linked polyubiquitin chains by the ubiquitin-activating enzyme

Journal of Biological Chemistry

Volumn 282, Issue 52, 2007, Pages 37454-37460

  Huzil, J Torin ^a   Pannu, Rajeet ^a,b   Ptak, Christopher ^a   Garen, Grace ^a   Ellison, Michael J ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b Regan Campbell Ward McCann   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYUBIQUITIN CHAINS; THIOLESTER;

ACTIVATION ANALYSIS; CATALYST ACTIVITY; ENZYME ACTIVITY; PROTEINS;

AMINO ACIDS;

CYSTEINE; LYSINE; POLYUBIQUITIN; PROTEASOME; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E1; UBIQUITIN PROTEIN LIGASE E2; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME INACTIVATION; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; UBIQUITINATION;

BINDING SITES; CATALYSIS; ESCHERICHIA COLI; LIGASES; LYSINE; MUTAGENESIS; POLYUBIQUITIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; UBIQUITIN; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITIN-CONJUGATING ENZYMES;

EID: 38049105510     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705242200     Document Type: Article

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