Core domain mutation (S86Y) selectively inactivates polyubiquitin chain synthesis catalyzed by E2-25K

Biochemistry

Volumn 37, Issue 27, 1998, Pages 9784-9792

  Mastrandrea, Lucy D ^a   Kasperek, Eileen M ^a   Niles, Edward G ^a   Pickart, Cecile M ^b  

^a UNIVERSITY AT BUFFALO   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYUBIQUITIN; UBIQUITIN;

ARTICLE; CONJUGATION; ENZYME ACTIVE SITE; ENZYME SYNTHESIS; MOLECULAR INTERACTION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION;

ALKYLATION; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BIOPOLYMERS; CATALYSIS; CATTLE; ENZYME ACTIVATION; HUMANS; HYDROLYSIS; LIGASES; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PHENOTYPE; POINT MUTATION; POLYUBIQUITIN; PROTEIN STRUCTURE, TERTIARY; RABBITS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN; TYROSINE; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINS;

FELIS CATUS; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0032493417     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9800911     Document Type: Article

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