Synthesis, structural characterization and biological evaluation of novel [1,2,4]triazolo [1,5-b][1,2,4]benzothiadiazine-benzothiazole conjugates as potential anticancer agents

Chemical Biology and Drug Design

Volumn 71, Issue 1, 2008, Pages 78-86

  Kamal, Ahmed ^a   Khan, M Naseer A ^a   Reddy, K Srinivasa ^a   Srikanth, Y V V ^a   Sridhar, B ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

1,2,4 triazolo 1,5 b 1,2,4 benzothiadiazines; Anticancer activity; Benzothiazoles; X ray crystallography

Indexed keywords

2 [(1,3 BENZOTHIAZOL 2 YLSULFANYL)METHYL] 10 METHYL 5,10 DIHYDRO 5LAMBDA 6 BENZO[E][1,2,4]TRIAZOLO[1,5 B][1,2,4]THIADIAZINE 5,5 DIONE; 2 [(1,3 BENZOTHIAZOL 2 YLSULFANYL)METHYL] 10 PHENYL 5,10 DIHYDRO 5LAMBDA 6 BENZO[E][1,2,4]TRIAZOLO[1,5 B][1,2,4]THIADIAZINE 5,5 DIONE; 2 [(6 ETHOXY 1,3 BENZOTHIAZOL 2 YL)SULFANYL]METHYL 10 METHYL 5,10 DIHYDRO 5LAMBDA 6 BENZO[E][1,2,4]TRIAZOLO[1,5 B][1,2,4]THIADIAZINE 5,5 DIONE; 2 [2 (1,3 BENZOTHIAZOL 2 YLSULFANYL)ETHYL] 10 METHYL 5,10 DIHYDRO 5LAMBDA 6 BENZO[E][1,2,4]TRIAZOLO[1,5 B][1,2,4]THIADIAZINE 5,5 DIONE; 2 [4 (1,3 BENZOTHIAZOL 2 YL) 2 METHOXYPHENOXY]METHYL 10 METHYL 5,10 DIHYDRO 5LAMBDA 6 BENZO[E][1,2,4]TRIAZOLO[1,5 B][1,2,4]THIADIAZINE 5,5 DIONE; 2 [4 (1,3 BENZOTHIAZOL 2 YL) 2 METHOXYPHENOXY]METHYL 10 PHENYL 5,10 DIHYDRO 5LAMBDA 6 BENZO[E][1,2,4]TRIAZOLO[1,5 B][1,2,4]THIADIAZINE 5,5 DIONE; 2 [4 (1,3 BENZOTHIAZOL 2 YL)PHENOXY]METHYL 10 PHENYL 5,10 DIHYDRO 5LAMBDA 6 BENZO[E][1,2,4]TRIAZOLO[1,5 B][1,2,4]THIADIAZINE 5,5 DIONE; [1,2,4]TRIAZOLO[1,5 B][1,2,4]BENZOTHIADIAZINE; ANTINEOPLASTIC AGENT; BENZOTHIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROMETRY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

AZO COMPOUNDS; BENZOTHIADIAZINES; BENZOTHIAZOLES; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 37849027512     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2007.00609.x     Document Type: Article

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