Synthesis and biological activity of new 2-amino-8-chloro-5,5-dioxo[1,2,4]triazolo[2,3-b][1,4,2]benzodithiazines

European Journal of Medicinal Chemistry

Volumn 41, Issue 5, 2006, Pages 633-639

  Pomarnacka, Elzbieta ^a   Bednarski, Patrick J ^b   Reszka, Przemysław ^b   Dziemidowicz Borys, Ewa ^a,b   Bieńczak, Andrzej ^a,b   Werel, Władysław ^a   Hałasa, Rafał ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Antibacterial activity; Cytotoxic activity; Triazolo 2,3 b 1,4,2 benzodithiazines

Indexed keywords

1 (6 CHLORO 1,1 DIOXO 1,4,2 BENZODITHIAZIN 3 YL) 4 (4 CHLOROPHENYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 1,4,2 BENZODITHIAZIN 3 YL) 4 (4 METHOXYPHENYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 1,4,2 BENZODITHIAZIN 3 YL) 4 (4 METHYLPHENYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 1,4,2 BENZODITHIAZIN 3 YL) 4 PHENYLSEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 7 METHOXYCARBONYL 1,4,2 BENZODITHIAZIN 3 YL) 4 (4 CHLOROPHENYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 7 METHOXYCARBONYL 1,4,2 BENZODITHIAZIN 3 YL) 4 (4 METHOXYPHENYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 7 METHYL 1,4,2 BENZODITHIAZIN 3 YL) 4 (1 NAPHTHYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 7 METHYL 1,4,2 BENZODITHIAZIN 3 YL) 4 (3,4 DICHLOROPHENYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 7 METHYL 1,4,2 BENZODITHIAZIN 3 YL) 4 (3,5 DICHLOROPHENYL)SEMICARBAZIDE; 1 (6 CHLORO 1,1 DIOXO 7 METHYL 1,4,2 BENZODITHIAZIN 3 YL) 4 (4 METHOXYPHENYL)SEMICARBAZIDE; 1 [6 CHLORO 1,1 DIOXO 7 (4 CHLOROPHENYLCARBAMOYL) 1,4,2 BENZODITHIAZIN 3 YL] 4 (4 CHLOROPHENYL)SEMICARBAZIDE; 1 [6 CHLORO 1,1 DIOXO 7 (4 CHLOROPHENYLCARBAMOYL) 1,4,2 BENZODITHIAZIN 3 YL] 4 (4 METHYLPHENYL)SEMICARBAZIDE; 2 AMINO 8 CHLORO 5,5 DIOXO[1,2,4]TRIAZOLO[2,3 B][1,4,2]BENZODITHIAZINE DERIVATIVE; 8 CHLORO 7 METHYL 2 (1 NAPHTHYLAMINO) 5,5 DIOXO [1,2,4] TRIAZOLO [2,3B] [1,4,2]BENZODITHIAZINE; 8 CHLORO 7 METHYL 2 (3,5 DICHLOROPHENYLAMINO) 5,5 DIOXO[1,2,4]TRIAZOLO[2,3 B][1,4,2]BENZODITHIAZINE; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG; 2 AMINO 8 CHLORO 5,5 DIOXO(1,2,4)TRIAZOLO(2,3 B)(1,4,2)BENZODITHIAZINE; 2-AMINO-8-CHLORO-5,5-DIOXO(1,2,4)TRIAZOLO(2,3-B)(1,4,2)BENZODITHIAZINE; ANTIINFECTIVE AGENT; THIAZINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MOLECULAR STRUCTURE; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZINES; TRIAZOLES;

EID: 33646761622     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.11.009     Document Type: Article

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