Identification of potent agonists acting at an endogenous atypical β3-adrenoceptor state that modulate lipolysis in rodent fat cells

European Journal of Pharmacology

Volumn 580, Issue 1-2, 2008, Pages 55-62

  Hamilton, Bradford S ^a   Doods, Henri N ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Adipocyte; Atypical; Beta adrenoceptor; Lipolysis

Indexed keywords

4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; 5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; N [2 BENZYLOXY 5 [2 [1,1 DIMETHYL 3 (4 PHENYLIMIDAZOL 1 YL)PROPYLAMINO] 1 HYDROXYETHYL]PHENYL]METHANESULPHONAMIDE FORMIATE; N [5 [2 [3 (5,6 DICHLOROBENZOIMIDAZOL 1 YL) 1,1 DIMETHYLPROPYLAMINO] 1 HYDROXYETYL] 2 HYDROXYPHENYL]METHANESULFONAMIDE CHLORIDE; SOM 1298; SOM 1459; UNCLASSIFIED DRUG;

ADIPOCYTE; AGONIST; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG IDENTIFICATION; DRUG POTENCY; DRUG RECEPTOR BINDING; FEMALE; LIGAND BINDING; LIPOLYSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ADIPOCYTES, WHITE; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CYCLIC AMP; ETHANOLAMINES; FEMALE; LIGANDS; LIPOLYSIS; MALE; MICE; MICE, KNOCKOUT; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, ADRENERGIC, BETA-3;

EID: 37649015774     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.10.065     Document Type: Article

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