Effect of PEG modification on subtilisin Carlsberg activity, enantioselectivity, and structural dynamics in 1,4-dioxane

Biotechnology and Bioengineering

Volumn 99, Issue 1, 2008, Pages 9-17

  Castillo, Betzaida ^a   Solá, Ricardo J ^a   Ferrer, Amaris ^b   Barletta, Gabriel ^b   Griebenow, Kai ^a  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^b UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

Bioconjugates; Covalent modification; Enzyme activity; FTIR; H D exchange; Non aqueous enzymology; Polyethylene glycol; Protein dynamics; Subtilisin Carlsberg

Indexed keywords

BIOCONJUGATES; NON AQUEOUS ENZYMOLOGY; PROTEIN STRUCTURAL DYNAMICS; SUBTILISIN CARLSBERGS;

AMIDES; CATALYSIS; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ORGANIC SOLVENTS; PROTEINS; SOLUTIONS;

POLYETHYLENE GLYCOLS;

BUTYRIC ACID; DIOXANE; MACROGOL; SUBTILISIN; SUBTILISIN CARLSBERG; UNCLASSIFIED DRUG; VINYL BUTYRATE;

ARTICLE; BIOCATALYST; CHEMICAL MODIFICATION; ENANTIOSELECTIVITY; ENZYME MODIFICATION; HYDROLYSIS; MOLECULAR DYNAMICS; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEOMICS; STRUCTURE ANALYSIS;

CATALYSIS; COMPUTER SIMULATION; DIOXANES; ENZYME ACTIVATION; MODELS, CHEMICAL; POLYETHYLENE GLYCOLS; PROTEIN CONFORMATION; SOLVENTS; SUBSTRATE SPECIFICITY; SUBTILISINS; WATER;

EID: 37549023093     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21510     Document Type: Article

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