Pulmonary lesions in female harlan sprague-dawley rats following two-year oral treatment with dioxin-like compounds

Toxicologic Pathology

Volumn 35, Issue 7, 2007, Pages 880-889

  Walker, Nigel J ^a   Yoshizawa, Katsuhiko ^b,c   Miller, Rodney A ^d   Brix, Amy E ^d   Sells, Donald M ^e   Jokinen, Micheal P ^f   Wyde, Michael E ^a   Easterling, Michael ^g   Nyska, Abraham ^a,h  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b ASTELLAS PHARMA INC   (Japan)

^c KANSAI MEDICAL UNIVERSITY   (Japan)

^d EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^e BATTELLE MEMORIAL INSTITUTE   (United States)

^f A Charles River Company   (United States)

^g Constella Group ^*  (United States)

^h MD EC 34 ^*  (Israel)

Author keywords

Bronchiolar metaplasia; Carcinogenesis; Cystic keratinizing epithelioma; Lung; Mixtures; TEFs

Indexed keywords

2,3,4,7,8 PENTACHLORODIBENZOFURAN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,3',4,4',5 PENTACHLOROBIPHENYL; BENZOFURAN DERIVATIVE; CYTOCHROME P450 1A1; DIBENZODIOXIN DERIVATIVE; DIOXIN; ETHOXYRESORUFIN DEETHYLASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; BRONCHIOLE; CANCER INCIDENCE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYSTIC KERATINIZING EPITHELIOMA; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; EPITHELIUM TUMOR; FEMALE; HEALTH PROGRAM; LUNG ALVEOLUS EPITHELIUM; LUNG LESION; METAPLASIA; NONHUMAN; PRIORITY JOURNAL; RAT; SQUAMOUS CELL CARCINOMA; SQUAMOUS CELL METAPLASIA;

ADMINISTRATION, ORAL; ANIMALS; BENZOFURANS; CYTOCHROME P-450 CYP1A1; FEMALE; LUNG; METAPLASIA; POLYCHLORINATED BIPHENYLS; RATS; RATS, SPRAGUE-DAWLEY; TETRACHLORODIBENZODIOXIN; TIME FACTORS;

RATTUS;

EID: 37549017381     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1080/01926230701748396     Document Type: Article

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