Olfactory Epithelial Metaplasia and Hyperplasia in Female Harlan Sprague–Dawley Rats Following Chronic Treatment with Polychlorinated Biphenyls

Toxicologic Pathology

Volumn 33, Issue 3, 2005, Pages 371-377

  Nyska, Abraham ^a   Yoshizawa, Katsuhiko ^a   Jokinen, Micheal P ^e   Brix, Amy E ^f   Sells, Donald M ^g   Wyde, Michael E ^b   Orzech, Denise P ^b   Kissling, Grace E ^c   Walker, Nigel J ^d  

^a Laboratory of Experimental Pathology   (United States)

^b Toxicology Operations Branch   (United States)

^c Biostatistics Branch   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e A Charles River Company   (United States)

^f EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^g Battelle Columbus Lab   (United States)

Author keywords

Dioxin; furans; hyperplasia; metaplasia; nasal cavity; olfactory epithelium; polychlorinated biphenyls; toxic equivalency factor

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; 2,3'4,4',5 PENTACHLOROBIPHENYL; 2,3,4,7,8 PENTACHLORODIBENZOFURAN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,3',4,4',5 PENTACHLOROBIPHENYL; BIPHENYL DERIVATIVE; CYTOCHROME P450 2E1; DIOXIN; FURAN DERIVATIVE; POLYCHLORINATED BIPHENYL; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CHRONIC TOXICITY; CONTROLLED STUDY; ENZYME ACTIVITY; HYPERPLASIA; METAPLASIA; MOLAR TOOTH; NONHUMAN; NOSE CAVITY; OLFACTORY BULB; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; RAT; RESPIRATORY EPITHELIUM; TISSUE REGENERATION;

ADMINISTRATION, ORAL; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYPERPLASIA; METAPLASIA; MOLECULAR STRUCTURE; OLFACTORY MUCOSA; POLYCHLORINATED BIPHENYLS; RATS; RATS, SPRAGUE-DAWLEY; TOXICITY TESTS, CHRONIC;

EID: 18144398171     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230590930209     Document Type: Article

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