Gingival carcinogenicity in female Harlan Sprague-Dawley rats following two-year oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds

Toxicological Sciences

Volumn 83, Issue 1, 2005, Pages 64-77

  Yoshizawa, Katsuhiko ^a   Walker, Nigel J ^a   Jokinen, Micheal P ^b   Brix, Amy E ^c   Sells, Donald M ^d   Marsh, Tiwanda ^a   Wyde, Michael E ^a   Orzech, Denise ^a   Haseman, Joseph K ^a   Nyska, Abraham ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b A Charles River Company   (United States)

^c EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^d Battelle Columbus Lab   (United States)

Author keywords

Dioxin; Dioxin like compounds; Gingival squamous hyperplasia; Rat; Squamous cell carcinoma

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; 2,3,4,7,8 PENTACHLORODIBENZOFURAN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3,3',4,4',5 PENTACHLOROBIPHENYL; ACETONE; CARCINOGEN; CORN OIL; POLYCHLORINATED BIPHENYL; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CANCER INCIDENCE; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CHEMICAL STRUCTURE; CHRONIC TOXICITY; CONTROLLED STUDY; FEMALE; GINGIVA DISEASE; GINGIVA HYPERPLASIA; MEDICAL DOCUMENTATION; MICROSCOPY; MOLAR TOOTH; MOUTH CARCINOMA; MOUTH CAVITY; NONHUMAN; PALATE; RAT; REVIEW; SQUAMOUS CELL CARCINOMA; TOOTH;

ADMINISTRATION, ORAL; ANIMALS; BENZOFURANS; CARCINOGENICITY TESTS; CARCINOMA, SQUAMOUS CELL; DIOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; GINGIVA; GINGIVAL NEOPLASMS; HYPERPLASIA; POLYCHLORINATED BIPHENYLS; RATS; RATS, SPRAGUE-DAWLEY; TETRACHLORODIBENZODIOXIN; TIME FACTORS;

ANIMALIA; ZEA MAYS;

EID: 19944426710     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi016     Document Type: Review

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