Physiopathology of schizophrenia: Current aspects;Fisiopatologia da esquizofrenia: Aspectos atuais

Revista de Psiquiatria Clinica

Volumn 34, Issue SUPPL. 2, 2007, Pages 198-203

  Neto, Ary Gadelha De Alencar Araripe ^a   Bressan, Rodrigo Affonseca ^a   Busatto Filho, Geraldo ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Dopamine hypothesis; Glutamate hypothesis; Neurodevelopment; Physiopathology; Schizophrenia

Indexed keywords

GLUTAMIC ACID;

BRAIN DEVELOPMENT; CLINICAL FEATURE; COGNITIVE DEFECT; DOPAMINERGIC ACTIVITY; DOPAMINERGIC TRANSMISSION; ENVIRONMENTAL FACTOR; EPIDEMIOLOGICAL DATA; EVIDENCE BASED PRACTICE; GENETIC ASSOCIATION; HEREDITY; HISTORY; HUMAN; MEDICAL LITERATURE; MEDLINE; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NEUROIMAGING; NEUROPATHOLOGY; NEUROTRANSMISSION; OBSTETRICS; PATHOPHYSIOLOGY; REVIEW; SCHIZOPHRENIA; SEROTONINERGIC TRANSMISSION;

EID: 37449030903     PISSN: 01016083     EISSN: 1806938X     Source Type: Journal    
DOI: 10.1590/S0101-60832007000800010     Document Type: Review

References (39)

1. Bogerts, B. - The neuropathology of schizophrenia diseases: historical aspects and present knowledge. Eur Arch Psychiatry Clin Neurosci 249(4): 2-13, 1999.
2. Bressan, R.A.; Pilowsky, L.S. - Hipótese glutamatérgica da esquizofrenia. Rev Bras Psiquiatr 25(3): 177-183, 2003.
3. Buka, S.L.; Tsuang, M.T.; Torrey, E.F.; Klebanoff, M.A.; Bernstein, D.; Yolken, R.H. - Maternal infections and subsequent psychosis among offsprings. Arch Gen Psychiatry 58:1032-1037, 1993.
4. Cannon, T.D. - On the nature and mechanisms of obstetric influences in schizophrenia: a review and synthesis of epidemiologic studies. Int Rev Psychiatry 9: 387-397, 1997.
5. Cannon, T.D.; Kaprio, J.; Lonqvist, J.; Huttunen, M.; Koskenvuo, M. - The genetic epidemiology of schizophrenia in a Finnish Twin Cohort. Arch Gen Psychiatry 55: 67-74, 1998.
6. Cardno, A.G.; Marshall, E.J.; Coid, B.; Macdonald, A.M.; Ribchester, T.R.; Davies et al. - Heritability estimates to psychosis disorders: The Maudsley twin psychosis series. Arch Gen Psychiatry 56(2): 162-168, 1999.
7. Caspi, A.; Moffit, T.E.; Cannon, M.; Mcclay, J.; Murray, R.; Harrington et al. - Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-methyltransferase gene: Longitudinal evidence of a gene x environment interaction. Biol Psychiatry 57: 1117-1127, 2005.
8. Elkis, H.; Friedman, L.; Wise, A.; Meltzer, H.Y. - Meta-analyses of studies of ventricular enlargement and cortical sulcal prominence in mood disorders. Comparisons with controls or patients with schizophrenia. Arch Gen Psychiatry 52: 735-746, 1995.
9. Fusar-Poli, P.; Perez, J.; Broome, M.; Borgwardt, S.; Placentino, A.; Caverzasi, E. et al. - Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis. Neurosci Biobehav Rev 31(4): 465-484, 2007.
10. Geddes, J.R.; Verdoux, H.; Takei, N.; Lawrie, S.M.; Murray, R.M. - Individual patient data meta-analysis of the association between schizophrenia and abnormalities of pregnancy and labour. Schizophr Bull 25: 113-123, 1999.
11. Glantz, L.A; Gilmore, J.H; Lieberman, J.A.; Jarskog, L.F. - Apoptotic mechanisms and the synaptic pathology of schizophrenia. Schizophr Res 81: 47-63, 2006.
12. Goff, D.C.; Coyle, J.T. - The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am J Psychiatry 158: 1367-1377, 2001.
13. Harisson, P.J. - The neuropathology of schizophrenia: A critical review of the data and their interpretation. Brain 122: 593-624, 1999.
14. Ho, B.C.; Andreasen, N.C.; Nopoulos, P.; Arndt, S.; Magnotta, V.; Flaum, M. - Progressive structural brain abnormalities and their relationship to clinical outcome: a longitudinal magnetic resonance imaging study early in schizophrenia. Arch Gen Psychiatry 60: 585-594, 2003.
15. Honea, R.; Crow, T.J.; Passingham, D.; Mackay, C.E. - Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am J Psychiatry 162(12): 2233-2245, 2005.
16. Hultman, C.M.; Sparen, P.; Takei, N.; Murray, R.M; Cnattingius, S. Prenatal and perinatal risk factors for schizophrenia, affective psychosis and reactive psychosis. Br Med J 310: 421-425, 1999.
17. Iqbal, N.; Van Praag, H. - The role of serotonin in schizophrenia. Eur NeuroPsychopharmacol, supl: 11-23, 1995.
18. Kapur, S.; Seeman, P. - Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics? A new hypothesis. Am J Psychiatry 158: 360-369, 2001.
19. Kapur, S.; Zipursky, R.; Jones, C.; Remington, G.; Houle, S. - Relationship between dopamine D2 occupancy, clinical response, and side effects: A double-blind PET study of first-episode schizophrenia. Am J Psychiatry 157, 4: 514-520, 2000.
20. Keshavan, M.S.; Diwadkar, V.A.; Montrose, D.M.; Rajarenthinam, R.; Sweeney, J.A. - Premorbid indicators and risk for schizophrenia: A selective review and update. Schizophr Res 79: 45-57, 2006.
21. Kraepelin, E. La Dementia precoz, edição em castelhano vol. I. Editorial Polemos, Buenos Aires, 1996.
22. Lara, D.R.; Brunstein, M.G.; Ghisolfi, E.S.; Lobato, M.I.; Belmonte_De Abreu, P.; Souza, D.O. - Allopurinol augmentation for poorly responsive schizophrenia. Int Clin Psychopharmacol 4: 53-55, 2001.
23. Lara, D.R.; Dall'igna, O.P.; Ghisolfi, E.S.; Brunstein, M.G. - Involvement of adenosine in the neurobiology of schizophrenia and its therapeutic implications. Prog Neuropsychopharmacol Biol Psychiatry 30: 617-629, 2006.
24. Laruelle, M. et al. - Single Photon Emission Comupterized Tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc Natl Acad Sci USA 93: 9235-9240, 1996.
25. Lewis, D.A.; Levitt, P. - Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci 25: 409-432, 2002.
26. Lieberman, J.A.; Perkins, D.; Belger, A.; Chakos, M.; Jarskog, F.; Boteva, K.; Gilmore, J. - The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches. Biol Psychiatry 50(11): 884-897, 2001.
27. Marder, S.P; van Kammen, D.P. - Dopamine receptor antagonists (Typical antipsychotics). In: Sadock, B.J.; Sadock, V.A. (eds.) Kaplan & Sadock's Comprehensive Textbook of Psychiatry, vol.II, 8.ed. Philadelphia: Lippincott Williams & Wilkins, 2817-2838, 2004.
28. Mcdonald, C.; Murray, R.M. - Early and late environmental risk factors for schizophrenia. Brain Res Rev 31: 130-137, 2000.
29. Seeman, P.; Chau-Wong, M.; Tedesco, J.; Wong, K. - Brain receptors fo antipsychotic drugs and dopamin: direct binding assays. Proc Natl Acad Sci USA, 72(11): 4376-4380, 1975.
30. Semple, D.M.; Mcintosh A.M.; Lawrie, S.M. - Cannabis as a risk factor for psychosis systematic review. J Psychopharmacol 19(2): 187-194, 2005.
31. Shergill, S.S.; Brammer, M.J.; Williams, S.C.; Murray, R.M.; Mcguire, P.K. - Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging. Arch Gen Psychiatry 57:1033-1038, 2000.
32. Steen, R.G.; Mull, C.; Mcclure, R.; Hamer, R.M.; Lieberman, J.A. - Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies. Br J Psychiatry 188: 510-518, 2006.
33. Stone, J.M.; Morrison, P.D.; Pilowsky, L.S. - Glutamate and dopamine dysregulation in schizophrenia: a synthesis and selective review. J Psychopharmacol, 2007.
34. Talbot, P.S; Laruelle, M. - The role of in vivo imaging with PET and SPECT in the eluciation of psychiatry drug action and new drug development. Eur Neuropsychopharmacol 12: 503-511, 2002.
35. Tandon, R. - Cholinergic aspects of schizophrenia. Br J Psychiatry (suppl 37): 7-11, 1999.
36. Verdoux, H.; Tournier, M.; Cougnard, A. - Impact of substance use on the onset of early psychosis. Schizophr Res 79: 69-75, 2005.
37. Weinberger, D.R. - From neuropathology to neurodevelopment. Lancet 346: 552-557, 1995.
38. Weinberger, D.R.; Berman, K.F.; Zec, R.F. - Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry 43: 114-124, 1986.
39. Wright, I.C.; Rabe-Hesketh, S.; Woodruff, P.W.; David, A.S.; Murray, R.M.; Bullmore, E.T. - Meta-analysis of regional brain volume in schizophrenia. Am J Psychiatry, 157: 16-25, 2000.