메뉴 건너뛰기




Volumn 5, Issue 6, 2007, Pages 1105-1111

Pharmacogenomics in prevention of diabetic cardiovascular disease: Utilization of the haptoglobin genotype in determining benefit from vitamin E

Author keywords

Antioxidant vitamins; Cardiovascular disease; Diabetes oxidative stress pharmacogenomics

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; DEFEROXAMINE; GLYCOPROTEIN; HAPTOGLOBIN; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN; HYDROGEN PEROXIDE; LOW DENSITY LIPOPROTEIN; PLACEBO; RAMIPRIL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; UBIQUINONE;

EID: 37349131252     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/14779072.5.6.1105     Document Type: Review
Times cited : (19)

References (45)
  • 1
    • 0028128943 scopus 로고
    • The oxidation hypothesis of atherosclerosis
    • Witztum JL. The oxidation hypothesis of atherosclerosis. Lancet 344, 793-795 (1994).
    • (1994) Lancet , vol.344 , pp. 793-795
    • Witztum, J.L.1
  • 2
    • 23944493587 scopus 로고    scopus 로고
    • Vitamin E, oxidative stress and inflammation
    • Singh U, Devaraj S, Jialal I. Vitamin E, oxidative stress and inflammation. Ann. Rev. Nutr. 25, 151-174 (2005).
    • (2005) Ann. Rev. Nutr , vol.25 , pp. 151-174
    • Singh, U.1    Devaraj, S.2    Jialal, I.3
  • 3
    • 26844564082 scopus 로고    scopus 로고
    • Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
    • Johansen JS, Harris A, Rychly D, Ergul A. Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Card. Diab. 4, 5-15 (2005).
    • (2005) Card. Diab , vol.4 , pp. 5-15
    • Johansen, J.S.1    Harris, A.2    Rychly, D.3    Ergul, A.4
  • 4
    • 33746383083 scopus 로고    scopus 로고
    • Common presence of non-transferrin bound iron among patients with Type II diabetes
    • Lee DH, Folsom AR, Harnack L, Halliwell B, Jacobs DR. Common presence of non-transferrin bound iron among patients with Type II diabetes. Diab. Care 29, 1090-1095 (2006).
    • (2006) Diab. Care , vol.29 , pp. 1090-1095
    • Lee, D.H.1    Folsom, A.R.2    Harnack, L.3    Halliwell, B.4    Jacobs, D.R.5
  • 5
    • 33646575616 scopus 로고    scopus 로고
    • Oxidative stress and diabetes associated complications
    • Ceriello PA. Oxidative stress and diabetes associated complications. Endo. Prac. 12, 60-62 (2006).
    • (2006) Endo. Prac , vol.12 , pp. 60-62
    • Ceriello, P.A.1
  • 6
    • 0032859788 scopus 로고    scopus 로고
    • Vitamin E and its function in membranes
    • Wang X, Quinn PJ. Vitamin E and its function in membranes. Prog. Lipid Res. 38, 309-316 (1999).
    • (1999) Prog. Lipid Res , vol.38 , pp. 309-316
    • Wang, X.1    Quinn, P.J.2
  • 7
    • 0037840165 scopus 로고    scopus 로고
    • Use of antioxidant vitamins for the prevention of cardiovascular disease: Meta-analysis of randomized trials
    • Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomized trials. Lancet 361, 2017-2023 (2003).
    • (2003) Lancet , vol.361 , pp. 2017-2023
    • Vivekananthan, D.P.1    Penn, M.S.2    Sapp, S.K.3    Hsu, A.4    Topol, E.J.5
  • 8
    • 33646098696 scopus 로고    scopus 로고
    • Role of diabetes in atherosclerosis pathogenesis. What have we learned from animal models?
    • Renard C, Van Obberghen E. Role of diabetes in atherosclerosis pathogenesis. What have we learned from animal models? Diab. Metab. 32, 15-29 (2006).
    • (2006) Diab. Metab , vol.32 , pp. 15-29
    • Renard, C.1    Van Obberghen, E.2
  • 9
    • 24644498663 scopus 로고    scopus 로고
    • Development of atherosclerosis in the diabetic BALB/c mice. Prevention with vitamin E administration
    • Otero P, Bonet B, Herrera E, Rabano A. Development of atherosclerosis in the diabetic BALB/c mice. Prevention with vitamin E administration. Atherosclerosis 182, 259-265 (2005).
    • (2005) Atherosclerosis , vol.182 , pp. 259-265
    • Otero, P.1    Bonet, B.2    Herrera, E.3    Rabano, A.4
  • 10
    • 14944367546 scopus 로고    scopus 로고
    • Vitamin E and cardiovascular disease: Observational studies
    • Gaziano JM. Vitamin E and cardiovascular disease: observational studies. Ann. NY Acad. Sci. 1031, 280-291 (2004).
    • (2004) Ann. NY Acad. Sci , vol.1031 , pp. 280-291
    • Gaziano, J.M.1
  • 11
    • 4744368242 scopus 로고    scopus 로고
    • Vitamins to prevent cancer: Supplementary problems
    • Forman D, Altman D. Vitamins to prevent cancer: supplementary problems. Lancet 364, 1193-1194 (2004).
    • (2004) Lancet , vol.364 , pp. 1193-1194
    • Forman, D.1    Altman, D.2
  • 13
    • 20044383911 scopus 로고    scopus 로고
    • Effects of long-term vitamin E supplementation on cardiovascular events and cancer
    • HOPE and HOPE-2 Trial Investigators
    • HOPE and HOPE-2 Trial Investigators. Effects of long-term vitamin E supplementation on cardiovascular events and cancer. JAMA 293, 1338-1347 (2005).
    • (2005) JAMA , vol.293 , pp. 1338-1347
  • 14
    • 14844292725 scopus 로고    scopus 로고
    • Is there any hope for vitamin E?
    • Brown BG, Crowley J. Is there any hope for vitamin E? JAMA 293, 1387-1390 (2005).
    • (2005) JAMA , vol.293 , pp. 1387-1390
    • Brown, B.G.1    Crowley, J.2
  • 15
    • 0037197722 scopus 로고    scopus 로고
    • Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
    • Steinberg D, Witztum JL. Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation 105, 2107-2111 (2002).
    • (2002) Circulation , vol.105 , pp. 2107-2111
    • Steinberg, D.1    Witztum, J.L.2
  • 16
    • 21444438990 scopus 로고    scopus 로고
    • Vitamin E in the primary prevention of cardiovascular disease and cancer: The Womens Health Study: a randomized controlled trial
    • Lee IM, Cook NR, Gaziano JM et al. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Womens Health Study: a randomized controlled trial. JAMA 294, 56-65 (2005).
    • (2005) JAMA , vol.294 , pp. 56-65
    • Lee, I.M.1    Cook, N.R.2    Gaziano, J.M.3
  • 17
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins or the combination for the prevention of coronary disease
    • Brown BG, Zhao XQ, Chait A et al. Simvastatin and niacin, antioxidant vitamins or the combination for the prevention of coronary disease. N. Engl. J. Med. 345, 1583-1592 (2001).
    • (2001) N. Engl. J. Med , vol.345 , pp. 1583-1592
    • Brown, B.G.1    Zhao, X.Q.2    Chait, A.3
  • 18
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin E supplementation and cardiovascular events in high risk patients
    • HOPE Trial Investigators
    • HOPE Trial Investigators. Vitamin E supplementation and cardiovascular events in high risk patients. N. Engl. J. Med. 342, 154-161 (2000).
    • (2000) N. Engl. J. Med , vol.342 , pp. 154-161
  • 19
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high risk individuals; a randomized placebo controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high risk individuals; a randomized placebo controlled trial. Lancet 360, 7-22 (2002).
    • (2002) Lancet , vol.360 , pp. 7-22
  • 20
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomized placebo controlled trial
    • Boaz M, Smetana S, Weinstein T et al. Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomized placebo controlled trial. Lancet 356, 1213-1218 (2000).
    • (2000) Lancet , vol.356 , pp. 1213-1218
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3
  • 21
    • 33646047815 scopus 로고    scopus 로고
    • Use of genomic signatures in therapeutics development in oncology and other diseases
    • Simon R, Wang SJ. Use of genomic signatures in therapeutics development in oncology and other diseases. Pharmacogenomics 6, 166-173 (2006).
    • (2006) Pharmacogenomics , vol.6 , pp. 166-173
    • Simon, R.1    Wang, S.J.2
  • 22
    • 17144460129 scopus 로고
    • Haptoglobin: The evolutionary product of duplication, unequal crossing over, and point mutation
    • Bowman BH, Kurosky A. Haptoglobin: the evolutionary product of duplication, unequal crossing over, and point mutation. Adv. Hum. Genet. 12, 189-261 (1982).
    • (1982) Adv. Hum. Genet , vol.12 , pp. 189-261
    • Bowman, B.H.1    Kurosky, A.2
  • 23
    • 0037021557 scopus 로고    scopus 로고
    • Haptoglobin phenotype and the risk of cardiovascular disease in individuals with diabetes: The Strong Heart Study
    • Levy AP, Hochberg I, Jablonski K et al. Haptoglobin phenotype and the risk of cardiovascular disease in individuals with diabetes: the Strong Heart Study. J. Am. Coll. Card. 40, 1984-1990 (2002).
    • (2002) J. Am. Coll. Card , vol.40 , pp. 1984-1990
    • Levy, A.P.1    Hochberg, I.2    Jablonski, K.3
  • 24
    • 0042536434 scopus 로고    scopus 로고
    • Haptoglobin genotype is predictive of major adverse cardiac events in the one year period after PTCA in individuals with diabetes
    • Roguin A, Koch W, Kastrati A, Aronson D, Schomig A, Levy AP. Haptoglobin genotype is predictive of major adverse cardiac events in the one year period after PTCA in individuals with diabetes. Diab. Care 26, 2628-2631 (2003).
    • (2003) Diab. Care , vol.26 , pp. 2628-2631
    • Roguin, A.1    Koch, W.2    Kastrati, A.3    Aronson, D.4    Schomig, A.5    Levy, A.P.6
  • 25
    • 24144486972 scopus 로고    scopus 로고
    • Haptoglobin polymorphism predicts 30-day mortality and heart failure in patients with diabetes and acute myocardial infarction
    • Suleiman M, Aronson D, Asleh R et al. Haptoglobin polymorphism predicts 30-day mortality and heart failure in patients with diabetes and acute myocardial infarction. Diabetes 19, 2802-2806 (2005).
    • (2005) Diabetes , vol.19 , pp. 2802-2806
    • Suleiman, M.1    Aronson, D.2    Asleh, R.3
  • 26
    • 33847671755 scopus 로고    scopus 로고
    • Haptoglobin genotype is a determinant of iron, lipid peroxidation and macrophage accumulation in the atherosclerotic plaque
    • Levy AP, Levy JE, Kalet-Litman S et al. Haptoglobin genotype is a determinant of iron, lipid peroxidation and macrophage accumulation in the atherosclerotic plaque. Arterioscl. Thromb Vasc. Biol. 27, 1419-1425 (2007).
    • (2007) Arterioscl. Thromb Vasc. Biol , vol.27 , pp. 1419-1425
    • Levy, A.P.1    Levy, J.E.2    Kalet-Litman, S.3
  • 27
    • 33847217986 scopus 로고    scopus 로고
    • Retinal capillary basement membrane thickness in diabetic mice genetically modified at the haptoglobin locus
    • Miller-Lotan R, Miller B, Aronson D, Asaf R, Nakhoul F, Levy AP. Retinal capillary basement membrane thickness in diabetic mice genetically modified at the haptoglobin locus. Diab. Met. Res. Rev. 23, 152-156 (2007).
    • (2007) Diab. Met. Res. Rev , vol.23 , pp. 152-156
    • Miller-Lotan, R.1    Miller, B.2    Aronson, D.3    Asaf, R.4    Nakhoul, F.5    Levy, A.P.6
  • 28
    • 21744457960 scopus 로고    scopus 로고
    • Increased renal hypertrophy in diabetic mice genetically modified at the haptoglobin locus
    • Miller-Lotan R, Herskowitz Y, Kalet-Litman S et al. Increased renal hypertrophy in diabetic mice genetically modified at the haptoglobin locus. Diab. Met. Res. Rev. 21, 332-337 (2005).
    • (2005) Diab. Met. Res. Rev , vol.21 , pp. 332-337
    • Miller-Lotan, R.1    Herskowitz, Y.2    Kalet-Litman, S.3
  • 29
    • 33845900436 scopus 로고    scopus 로고
    • Haptoglobin genotype determines myocardial infarct size in diabetic mice
    • Blum S, Asaf R, Guetta J et al. Haptoglobin genotype determines myocardial infarct size in diabetic mice. J. Am. Coll. Card. 49, 82-87 (2007).
    • (2007) J. Am. Coll. Card , vol.49 , pp. 82-87
    • Blum, S.1    Asaf, R.2    Guetta, J.3
  • 30
    • 33845665664 scopus 로고    scopus 로고
    • Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo
    • Asleh R, Miller-Lotan R, Aviram M et al. Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo. Circ. Res. 99, 1419-1425 (2006).
    • (2006) Circ. Res , vol.99 , pp. 1419-1425
    • Asleh, R.1    Miller-Lotan, R.2    Aviram, M.3
  • 31
    • 0021711640 scopus 로고
    • Hemoglobin - a biologic Fenton reagent
    • Sadrzadeh SMH, Graf E, Panter SS et al. Hemoglobin - a biologic Fenton reagent. J. Biol. Chem. 259, 14354-14356 (1984).
    • (1984) J. Biol. Chem , vol.259 , pp. 14354-14356
    • Sadrzadeh, S.M.H.1    Graf, E.2    Panter, S.S.3
  • 32
    • 0035895080 scopus 로고    scopus 로고
    • Structure/function analysis of the anti-oxidant properties of haptoglobin
    • Frank M, Lache O, Enav B et al. Structure/function analysis of the anti-oxidant properties of haptoglobin. Blood 98, 3693-3698 (2001).
    • (2001) Blood , vol.98 , pp. 3693-3698
    • Frank, M.1    Lache, O.2    Enav, B.3
  • 33
    • 0030766447 scopus 로고    scopus 로고
    • Oxidation of low density lipoprotein by hemoglobin stems from a heme initiated globin radical: Antioxidant role of haptoglobin
    • Miller YI, Altamentova SM, Shaklai N. Oxidation of low density lipoprotein by hemoglobin stems from a heme initiated globin radical: antioxidant role of haptoglobin. Biochemistry 36, 12189-12198 (1997).
    • (1997) Biochemistry , vol.36 , pp. 12189-12198
    • Miller, Y.I.1    Altamentova, S.M.2    Shaklai, N.3
  • 34
    • 0016615657 scopus 로고
    • The fate of circulating hemoglobin
    • Hershko C. The fate of circulating hemoglobin. Br. J. Hematol. 29, 199 (1975).
    • (1975) Br. J. Hematol , vol.29 , pp. 199
    • Hershko, C.1
  • 35
    • 0035843134 scopus 로고    scopus 로고
    • Identification of the hemoglobin scavenger receptor
    • Kristiansen M, Graversen JH, Jacobsen C et al. Identification of the hemoglobin scavenger receptor. Nature 409, 198-201 (2001).
    • (2001) Nature , vol.409 , pp. 198-201
    • Kristiansen, M.1    Graversen, J.H.2    Jacobsen, C.3
  • 36
    • 0036174088 scopus 로고    scopus 로고
    • CD163: A signal receptor scavenging haptoglobin hemoglobin complexes from plasma
    • Graversen JH, Madsen M, Moestrup SK. CD163: a signal receptor scavenging haptoglobin hemoglobin complexes from plasma. Int. J. Biochem. Cell Biol. 234, 309-314 (2002).
    • (2002) Int. J. Biochem. Cell Biol , vol.234 , pp. 309-314
    • Graversen, J.H.1    Madsen, M.2    Moestrup, S.K.3
  • 38
    • 14844345323 scopus 로고    scopus 로고
    • Haptoglobin genotype and diabetes dependent differences in iron mediated oxidative stress in vitro and in vivo
    • Asleh R, Guetta J, Kalet-Litman S, Miller-Lotan R, Levy AP. Haptoglobin genotype and diabetes dependent differences in iron mediated oxidative stress in vitro and in vivo. Circ. Res. 96, 435-441 (2005).
    • (2005) Circ. Res , vol.96 , pp. 435-441
    • Asleh, R.1    Guetta, J.2    Kalet-Litman, S.3    Miller-Lotan, R.4    Levy, A.P.5
  • 39
    • 0033955735 scopus 로고    scopus 로고
    • Advances in surface plasmon resonance biosensor analysis
    • Rich RL, Myszka DG. Advances in surface plasmon resonance biosensor analysis. Curr. Opin. Biotech. 11, 54-61 (2000).
    • (2000) Curr. Opin. Biotech , vol.11 , pp. 54-61
    • Rich, R.L.1    Myszka, D.G.2
  • 40
    • 1842539298 scopus 로고    scopus 로고
    • Haptoglobin phenotypes differ in their ability to inhibit heme transfer from hemoglobin to LDL
    • Bamm VV, Tsemakhovich VA, Shaklai M, Shaklai N. Haptoglobin phenotypes differ in their ability to inhibit heme transfer from hemoglobin to LDL. Biochemistry 43, 3899-3906 (2004).
    • (2004) Biochemistry , vol.43 , pp. 3899-3906
    • Bamm, V.V.1    Tsemakhovich, V.A.2    Shaklai, M.3    Shaklai, N.4
  • 41
    • 0038042030 scopus 로고    scopus 로고
    • Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease
    • Asleh R, Marsh S, Shiltruck M et al. Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease. Circ. Res. 92, 1193-1200 (2003).
    • (2003) Circ. Res , vol.92 , pp. 1193-1200
    • Asleh, R.1    Marsh, S.2    Shiltruck, M.3
  • 43
    • 0037109184 scopus 로고    scopus 로고
    • Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans. Role of oxidative stress
    • Esposito K, Nappo F, Marfella R et al. Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans. Role of oxidative stress. Circulation 106, 2067-2072 (2002).
    • (2002) Circulation , vol.106 , pp. 2067-2072
    • Esposito, K.1    Nappo, F.2    Marfella, R.3
  • 44
    • 0042393597 scopus 로고    scopus 로고
    • High glucose induced expression of proinflammatory cytokine and chemokine genes in monocytic cells
    • Shanmugam N, Reddy MA, Guha M, Natarajan R. High glucose induced expression of proinflammatory cytokine and chemokine genes in monocytic cells. Diabetes 52, 1256-1264 (2003).
    • (2003) Diabetes , vol.52 , pp. 1256-1264
    • Shanmugam, N.1    Reddy, M.A.2    Guha, M.3    Natarajan, R.4
  • 45
    • 7444241367 scopus 로고    scopus 로고
    • The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes
    • Levy AP, Gerstein HC, Miller-Lotan R et al. The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes. Diab. Care 27, 2767 (2004).
    • (2004) Diab. Care , vol.27 , pp. 2767
    • Levy, A.P.1    Gerstein, H.C.2    Miller-Lotan, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.