Overexpression of PPK-1, the Caenorhabditis elegans Type I PIP kinase, inhibits growth cone collapse in the developing nervous system and causes axonal degeneration in adults

Developmental Biology

Volumn 313, Issue 1, 2008, Pages 384-397

  Weinkove, David ^b,c   Bastiani, Michael ^a   Chessa, Tamara A M ^b   Joshi, Deepa ^a   Hauth, Linda ^a   Cooke, Frank T ^c   Divecha, Nullin ^b   Schuske, Kim ^a  

^a UNIVERSITY OF UTAH   (United States)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Axon outgrowth; Caenorhabditis elegans; Neuron degeneration; Neuron maintenance; PI(4,5)P2; PIP5K

Indexed keywords

PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; TYPE 1 PHOSPHATIDYLINOSITOL PHOSPHATE KINASE; UNCLASSIFIED DRUG;

ADULTHOOD; ARTICLE; CAENORHABDITIS ELEGANS; CELL MEMBRANE; CONTROLLED STUDY; EMBRYO; GROWTH CONE; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; NERVE CELL DEGENERATION; NERVE FIBER; NERVE FIBER DEGENERATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CAENORHABDITIS ELEGANS; EUKARYOTA;

EID: 37349031562     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2007.10.029     Document Type: Article

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