Unique natural antioxidants (NAOs) and derived purified components inhibit cell cycle progression by downregulation of ppRb and E2F in human PC3 prostate cancer cells

FEBS Letters

Volumn 573, Issue 1-3, 2004, Pages 31-37

  Bakshi, Shlomo ^a   Bergman, Margalit ^a   Dovrat, Sara ^a   Grossman, Shlomo ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

CDK, cyclin dependent kinase; EGCG, epigallocathecin 3 gallate; MTT, 3 (4,5 dimethylthiazol 2 yl) 2,5 diphenyl tetrazolium bromide; NAO, natural antioxidant; PCA, prostate cancer; TRAMP, transgenic adenocarcinoma mouse prostate

Indexed keywords

ANTIOXIDANT; CYCLIN A; CYCLIN DEPENDENT KINASE 2; POLYPHENOL DERIVATIVE; PROTEIN DERIVATIVE; PROTEIN P107; PROTEIN P21; TRANSCRIPTION FACTOR E2F1;

ARTICLE; CANCER CELL; CELL CYCLE; CELL CYCLE G1 PHASE; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DERIVATIZATION; DOWN REGULATION; DRUG EFFECT; HUMAN; HUMAN CELL; MALE; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; STARVATION; STATISTICAL SIGNIFICANCE;

ANTIOXIDANTS; CDC2-CDC28 KINASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; CYCLIN A; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; FLAVONOIDS; G1 PHASE; HUMANS; MALE; PHENOLS; PHOSPHORYLATION; PLANT EXTRACTS; PROSTATIC NEOPLASMS; RETINOBLASTOMA PROTEIN; S PHASE; SPINACIA OLERACEA; TRANSCRIPTION FACTORS;

SPINACIA OLERACEA;

EID: 4344698475     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.06.101     Document Type: Article

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