The advantages of being locked: Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozyme

Journal of Biological Chemistry

Volumn 282, Issue 49, 2007, Pages 35510-35518

  Donini, Stefano ^a   Clerici, Marcello ^a   Wengel, Jesper ^b   Vester, Birte ^b   Peracchi, Alessio ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; ENZYME ACTIVITY; THERMODYNAMIC STABILITY;

BINDING PROCESS; INTRAMOLECULAR CLEAVAGE; KINETIC BARRIER; LOCKED NUCLEIC ACID (LNA);

NUCLEIC ACIDS;

DEOXYRIBOZYME; LOCKED NUCLEIC ACID; MESSENGER RNA; MONOMER; NUCLEOTIDE; RNA;

ARTICLE; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME SUBSTRATE; MOLECULAR BIOLOGY; MOLECULAR STABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA STRUCTURE; THERMODYNAMICS;

DNA, CATALYTIC; KINETICS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; ONCOGENE PROTEINS, VIRAL; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, VIRAL; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

HUMAN PAPILLOMAVIRUS TYPE 16;

EID: 37249019972     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706993200     Document Type: Article

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