Effect of vasoactive intestinal polypeptide (VIP) antagonism on rat jejunal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins

Gut

Volumn 47, Issue 3, 2000, Pages 382-386

  Mourad, F H ^a   Nassar, C F ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

Cholera toxin; Enteric nervous system; Escherichia coli toxins; Intestinal secretion; Vasoactive intestinal polypeptide

Indexed keywords

CHOLERA TOXIN; ESCHERICHIA COLI ENTEROTOXIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE ANTAGONIST;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; CHOLERA; CONTROLLED STUDY; ELECTROLYTE TRANSPORT; ESCHERICHIA COLI; HORMONE INHIBITION; INTESTINE FLUID; INTESTINE INNERVATION; INTESTINE SECRETION; JEJUNUM; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BACTERIAL TOXINS; CHOLERA TOXIN; ENTERIC NERVOUS SYSTEM; ENTEROTOXINS; ESCHERICHIA COLI; INTESTINAL ABSORPTION; INTESTINAL SECRETIONS; RATS; RATS, SPRAGUE-DAWLEY; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0033850197     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.47.3.382     Document Type: Article

References (44)

1. 1 Nilsson O, Cassutto J, Larsson PA, et al. 5-Hydroxytryptamine and cholera secretion: a histochemical and physiological study in cats. Gut 1983;24:542-8.
2. 2, and cyclic adenosine monophosphate in cholera toxin-induced fluid secretion in the small intestine of the rat in vivo. Gastroenterology 1989;96:368-76.
3. 1 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion in the rat. Gastroenterology 1990;99:83-9.
4. 4 Cassuto J, Jodal M, Tuttle R, et al. On the role of intramural nerves in the pathogenesis of choleraic secretion. Scand J Gastroenterol 1981;16:377-84.
5. 5 Sjoqvist A, Fahrenkrug J, Jodal M, et al. The effect of splanchnic nerve stimulation and neuropeptide Y on cholera secretion and release of vasoactive intestinal polypeptide in the feline small intestine. Acta Physiol Scand 1988;133:289-95.
6. 6 Cassuto J, Fahrenkrug J, Jodal M, et al. Release of vasoactive intestinal polypeptide from the cat small intestine exposed to cholera toxin. Gut 1981;22:958-63.
7. 7 Cristophe J, Svoboda M, Lambert M, et al. Effector mechanisms of peptides of the VIP family. Peptides 1986;7 (suppl 1):101-7.
8. 8 Lundgren O, Svanvik J, Jivegard L. Enteric nervous system. I. Physiology and pathophysiology of the intestinal tract. Dig Dis Sci 1989;34:264-83.
9. 9 Sack BS. Enterotoxigenic Escherichia coli: identification and characterisation. J Infect Dis 1980;142:279-85.
10. 10 Field M. Modes of action of enterotoxins from Vibrio cholerae and Escherichia coli. Rev Infect Dis 1979;1:918-25.
11. 11 Spangler BD. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev 1992;56:622-47.
12. 12 Clements JD, Finkelstein RA. Isolation and characterisation of homogeneous heat-labile enterotoxins with high specific activity from Escherichia coli cultures. Infect Immun 1979;24:760-9.
13. 13 Griffith SL, Critchley DR. Characterisation of the binding sites for Escherichia coli heat-labile toxin type I in intestinal brush borders. Biochim Biophys Acta 1991;1075:154-61.
14. 14 Mourad FH, O'Donnell LJD, Dias JA, et al. Role of 5-hydroxytryptamine type 3 receptors in rat intestinal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins. Gut 1995;37:340-5.
15. 15 Turvill JL, Mourad FH, Farthing MJG. Crucial role for 5-HT in cholera but not Escherichia coli heat-labile enterotoxin-intestinal secretion in rats. Gastroenterologe 1999;115:883-90.
16. 16 Nzegwu HC, Levin RJ. Luminal capsaicin inhibits fluid secretion induced by enterotoxin E. coli LT but not by bethanechol in rat intestine in vivo. J Physiol 1996;495P: 95-6P.
17. 17 Scoot A, Forsyth GW, Kapitany RA, et al. Effect of isolated heat stable enterotoxin produced by Escherichia coli on fluid secretion and cyclic nucleotide level in the jejunum of weanling pig. Can J Physiol Pharmacol 1980;58:772-7.
18. 18 Hughes JM, Murad F, Chang B, et al. Role of cyclic GMP in the action of heat stable enterotoxin of Escherichia coli. Nature 1978;271:755-6.
19. 19 Field M, Graf LH, Laird WJ, et al. Heat stable enterotoxin of Escherichia coli: In vitro effects on guanylate cyclase activity, cyclic GMP concentration and ion transport in small intestine. Proc Natl Acad Sci USA 1978;75:2800-4.
20. 20 Eklund S, Jodal M, Lundgren O. The enteric nervous system participates in the secretory response to the heat stable enterotoxins of Escherichia coli in rats and cats. Neuroscience 1985;14:673-81.
21. 21 Rolfe V, Levin RJ, Young A. Electrogenic secretion in rat intestine in vitro activated by E coli STa is not mediated by local release of 5-hydroxytryptamine. J Physiol 1992;446: 107P.
22. 22 Rolfe V, Levin RJ. Enterotoxin Escherichia coli STa activates a nitric oxide-dependent myenteric plexus secretory reflex in the rat ileum. J Physiol 1994;475:531-7.
23. 23 Nzegwu HC, Levin RJ. Luminal capsaicin inhibits fluid secretion induced by enterotoxin E. coli Sta but not by carbachol, in vivo in rat small and large intestine. Exp Physiol 1996;81:313-15.
24. 24 Rolston DDK, Borodo MM, Kelly MJ, et al. Efficacy of oral rehydration solutions in a rat model of secretory diarrhoea. J Paediatr Gastroenterol Nutr 1987;6:624-30.
25. 25 Lenz HJ, Silverman TA. Effects of cerebral TRH on intestinal water transport: role of vagal, muscarinic, and VIP pathways. Am J Physiol 1995,269:G138-43.
26. 26 Schulzke J-D, Riecken E-O, Fromm M. Distention-induced electrogenic Cl secretion is mediated via VIP-ergic neurons in rat rectal colon. Am J Physiol 1995;268:G725-31.
27. 27 Giannella RA. Suckling mouse model for detection of heat stable Escherichia coli enterotoxin: characteristics of the model. Infect Immun 1976;14:95-9.
28. 28 Castagliuolo I, LaMont JT, Kelly CP, et al. Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin. Gastroenterology 1994;107:657-65.
29. 29 Nzegwu HC, Levin RJ. Tachykinin NK-2 receptor antagonist MEN 10,627 selectively inhibits fluid secretion induced by luminal enterotoxin E. coli Sta in the rat intestine in vivo. J Physiol 1997;499P:100P.
30. 30 Eklund S, Karlstrom L, Rokaeus A, et al. Effects of cholera toxin, Escherichia coli heat stable toxin and sodium deoxycholate on neurotensin release from the ileum in vivo. Regul Pept 1989;26:241-52.
31. 31 Goyal RK, Hirano I. The enteric nervous system. N Engl J Med 1996;334:1106-15.
32. 32 Keast JR, Furness JB, Costa M. Distribution of certain peptide containing nerve fibers and endocrine cells in the gastrointestinal tract in five mammalian species. J Comp Neurol 1985;236:403-22.
33. 33 Aimi Y, Kimura H, Kinoshita T, et al. Histochemical localization of nitric oxide in rat enteric nervous system. Neuroscience 1993;53:553-60.
34. 34 Waldman D, Gardver J, Zfass A, et al. Effect of vasoactive intestinal peptide, secretion and related peptides on rat colonic transport and adenylate cyclase activity. Gastroenterology 1977;73:518-23.
35. 35 Eklund S, Joldal M, Lundgren O, et al. Effects of vasoactive intestinal polypeptide on blood flow, motility and fluid transport in the gastrointestinal tract of the cat. Acta Physiol Scand 1979;105:461-8.
36. 36 Eklund S, Sjoqvist A, Fahrenkrug J, et al. Somatostatin and methionine-enkephalin inhibit cholera toxin-induced jejunal net fluid secretion and release of vasoactive intestinal polypeptide in the cat in vivo. Acta Physiol Scand 1988;133: 551-7.
37. 37 Cox HM, Cuthbert AW. Secretory actions of vasoactive intestinal polypeptide, peptide histidine isoleucine and helodermin in rat small intestine: the effects of putative VIP antagonists upon VIP-induced ion secretion. Regul Pept 1989;26:127-35.
38. 38 Burleigh DE, Kirkham SE. Lack of effect of three putative vasoactive intestinal peptide receptor antagonists on vasoactive intestinal peptide-induced secretory responses in rat colon. Eur J Pharmacol 1993;249:239-42.
39. 39 Turvill JL, Connor P, Farthing MJG. Action of non-peptide substance P antagonist, CP 96,345 on cholera toxin and E coli enterotoxin-induced secretion. Gastroenterology 1998; 114:A1007.
40. 40 Jiang MM, Kirchgessner A, Gershon MD, et al. Cholera toxin-sensitive neurons in guinea pig submucosal plexus. Am J Physiol 1993;264 G86-94.
41. 41 Rolfe VE, Levin RJ. Vagotomy inhibits the jejunal fluid secretion activated by luminal ileal Escherichia coli STa in the rat in vivo. Gut 1999;44:615-19.
42. 42 Llewellyn-Smith IJ, Song Z-M, Costa M, Bredt DS, Snyder SH. Ultrastructural localisation of nitric oxide synthase immunoreactivity in guinea-pig enteric neurons. Brain Res 1992;577:337-42.
43. 43 Allescher HD, Kurjak M, Huber A, Trudung P, Schudziarra V. Regulation of VIP release from rat enteric nerve terminals: evidence for a stimulatory effect of NO. Am J Physiol 1996;271:G568-74.
44. 44 Daniel EE, Haugh C, Woskowska Z, Cipris S, Jury J, Fox-Threlkeld JET. Role of nitric oxide-related inhibition in intestinal function: relation to vasoactive intestinal polypeptide. Am J Physiol 1994;266:G31 9.