Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha

Journal of Virology

Volumn 77, Issue 10, 2003, Pages 5902-5910

  Sinn, Patrick L ^a   Hickey, Melissa A ^a   Staber, Patrick D ^a   Dylla, Douglas E ^a   Jeffers, Scott A ^b   Davidson, Beverly L ^a   Sanders, David A ^b   McCray Jr , Paul B ^a  

^a UNIVERSITY OF IOWA   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; FOLIC ACID RECEPTOR ALPHA; LENTIVIRUS VECTOR; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; RECEPTOR; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ARTICLE; BINDING AFFINITY; CELL CULTURE; CELL IMMORTALIZATION; CONCENTRATION (PARAMETERS); EBOLA VIRUS; ENZYMATIC ASSAY; EPITHELIUM CELL; EXTRACELLULAR SPACE; FELINE IMMUNODEFICIENCY VIRUS; FILOVIRUS; GENE THERAPY; GENE TRANSFER; GLYCOSYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MARBURG VIRUS; PRIORITY JOURNAL; PROTEIN DOMAIN; RESPIRATORY EPITHELIUM; SURFACE PROPERTY; VIRUS ENVELOPE; VIRUS TYPING;

ANIMALS; CARRIER PROTEINS; CATS; CELL POLARITY; CELLS, CULTURED; EPITHELIAL CELLS; FILOVIRIDAE; GENETIC VECTORS; HUMANS; IMMUNODEFICIENCY VIRUS, FELINE; RECEPTORS, CELL SURFACE; RESPIRATORY SYSTEM; TRANSDUCTION, GENETIC; VIRAL ENVELOPE PROTEINS;

EID: 0038814328     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.10.5902-5910.2003     Document Type: Article

References (34)

1. Alvarez, C. P., F. Lasala, J. Carrillo, O. Muñiz, A. L. Corbí, and R. Delgado. 2002. C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in trans. J. Virol. 76:6841-6844.
2. Chan, S. Y., C. J. Empig, F. J. Welte, R. F. Speck, A. Schmaljohn, J. F. Kreisberg, and M. A. Goldsmith. 2001. Folate receptor-alpha is a cofactor for cellular entry by Marburg and Ebola viruses. Cell 106:117-126.
3. Christodoulopoulos, I., and P. M. Cannon. 2001. Sequences in the cytoplasmic tail of the gibbon ape leukemia virus envelope protein that prevent its incorporation into lentivirus vectors. J. Virol. 75:4129-4138.
4. Compans, R. W. 1995. Virus entry and release in polarized epithelial cells. Curr. Top. Microbiol. Immunol. 202:209-219.
5. Cozens, A. L., M. J. Yezzi, K. Kunzelmann, T. Ohrui, L. Chin, K. Eng, W. E. Finkbeiner, J. H. Widdicombe, and D. C. Gruenert. 1994. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am. J. Respir. Cell Mol. Biol. 10:38-47.
6. Duan, D., Y. Yue, Z. Yan, P. B. McCray, Jr., and J. F. Engelhardt. 1998. Polarity influences the efficiency of recombinant adenoassociated virus infection in differentiated airway epithelia. Hum. Gene Ther. 9:2761-2776.
7. Franklin, W. A., M. Waintrub, D. Edwards, K. Christensen, P. Prendegrast, J. Woods, P. A. Bunn, and J. F. Kolhouse. 1994. New anti-lung-cancer antibody cluster 12 reacts with human folate receptors present on adenocarcinoma. Int. J. Cancer Suppl. 8:89-95.
8. Grange, M. P., V. Blot, L. Delamarre, I. Bouchaert, A. Rocca, A. DautryVarsat, and M. C. Dokhelar. 2000. Identification of two intracellular mechanisms leading to reduced expression of oncoretrovirus envelope glycoproteins at the cell surface. J. Virol. 74:11734-11743.
9. Jeffers, S. A., D. A. Sanders, and A. Sanchez. 2002. Covalent modifications of the Ebola virus glycoprotein. J. Virol. 76:12463-12472.
10. Johnson, E., N. Jaax, J. White, and P. Jahrling. 1995. Lethal experimental infections of rhesus monkeys by aerosolized Ebola virus. Int. J. Exp. Pathol. 76:227-236.
11. Johnston, J. C., M. Gasmi, L. E. Lim, J. H. Elder, J.-K. Yee, D. J. Jolly, K. P. Campbell, B. L. Davidson, and S. L. Sauter. 1999. Minimum requirements for efficient transduction of dividing and nondividing cells by feline immunodeficiency virus vectors. J. Virol. 73:4991-5000.
12. Kang, Y., C. S. Stein, J. A. Heth, P. L. Sinn, A. K. Penisten, P. D. Staber, K. L. Ratliff, H. Shen, C. K. Barker, I. Martins, C. M. Sharkey, D. A. Sanders, P. B. McCray, Jr., and B. L. Davidson. 2002. In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River virus glycoproteins. J. Virol. 76:9378-9388.
13. Karp, P. H., T. O. Moniger, S. P. Weber, T. S. Nesselhauf, J. L. Launspach, J. Zabner, and M. J. Welsh. 2002. An in vitro model of differentiated human airway epithelia. Methods Mol. Biol. 188:115-137.
14. Kobinger, G. P., D. J. Weiner, Q. C. Yu, and J. M. Wilson. 2001. Filoviruspseudotyped lentiviral vector can efficiently and stably transduce airway epithelia in vivo. Nat. Biotechnol. 19:225-230.
15. Lisanti, M. P., I. W. Caras, M. A. Davitz, and E. Rodriguez-Boulan. 1989. A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells. J. Cell Biol. 109:2145-2156.
16. + cells. J. Virol. 71:3341-3345.
17. Miller, A. D. 1996. Cell-surface receptors for retroviruses and implications for gene transfer. Proc. Natl. Acad. Sci. USA 93:11407-11413.
18. Miotti, S., S. Canevari, S. Menard, D. Mezzanzanica, G. Porro, S. M. Pupa, M. Regazzoni, E. Tagliabue, and M. I. Colnaghi. 1987. Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity. Int. J. Cancer 39:297-303.
19. Poumbourios, P., R. J. Center, K. A. Wilson, B. E. Kemp, and B. Kobe. 1999. Evolutionary conservation of the membrane fusion machine. IUBMB Life 48:151-156.
20. Sanchez, A., M. P. Kiley, B. P. Holloway, and D. D. Auperin. 1993. Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus. Virus Res. 29:215-240.
21. Sandrin, V., B. Boson, P. Salmon, W. Gay, D. Negre, R. Le Grand, D. Trono, and F. L. Cosset. 2002. Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates. Blood 100:823-832.
22. Simmons, G., R. J. Wool-Lewis, F. Baribaud, R. C. Netter, and P. Bates. 2002. Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence. J. Virol. 76:2518-2528.
23. Sinn, P. L., X. Zhang, and C. D. Sigmund. 1999. JG cell expression and partial regulation of a human renin genomic transgene driven by a minimal renin promoter. Am. J. Physiol. 277:F634-F642.
24. Stitz, J., C. J. Buchholz, M. Engelstadter, W. Uckert, U. Bloemer, I. Schmitt, and K. Cichutek. 2000. Lentiviral vectors pseudotyped with envelope glycoproteins derived from gibbon ape leukemia virus and murine leukemia virus 10A1. Virology 273:16-20.
25. Walters, R. W., T. Grunst, J. M. Bergelson, R. W. Finberg, M. J. Welsh, and J. Zabner. 1999. Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia. J. Biol. Chem. 274:10219-10226.
26. Wang, G., B. L. Davidson, P. Melchert, V. A. Slepushkin, H. H. G. van Es, M. Bodner, D. J. Jolly, and P. B. McCray, Jr. 1998. Influence of cell polarity on retrovirus-mediated gene transfer to differentiated human airway epithelia. J. Virol. 72:9818-9826.
27. Wang, G., P. L. Sinn, and P. B. McCray, Jr. 2000. Development of retroviral vectors for gene transfer to airway epithelia. Curr. Opin. Mol. Ther. 2:497-506.
28. Wang, G., P. L. Sinn, J. Zabner, and P. B. McCray, Jr. 2002. Gene transfer to airway epithelia using feline immunodeficiency virus-based lentivirus vectors. Methods Enzymol. 346:500-514.
29. Wang, G., V. Slepushkin, J. Zabner, S. Keshavjee, J. C. Johnston, S. L. Sauter, D. J. Jolly, T. W. Dubensky, Jr., B. L. Davidson, and P. B. McCray, Jr. 1999. Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect. J. Clin. Investig. 104:R55-R62.
30. Will, C., E. Mühlberger, D. Linder, W. Slenczka, H.-D. Klenk, and H. Feldmann. 1993. Marburg virus gene 4 encodes the virion membrane protein, a type I transmembrane glycoprotein. J. Virol. 67:1203-1210.
31. Wool-Lewis, R. J., and P. Bates. 1998. Characterization of Ebola virus entry by using pseudotyped viruses: identification of receptor-deficient cell lines. J. Virol. 72:3155-3160.
32. Yang, Z. Y., H. J. Duckers, N. J. Sullivan, A. Sanchez, E. G. Nabel, and G. J. Nabel. 2000. Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury. Nat. Med. 6:886-889.
33. Zeilfelder, U., and V. Bosch. 2001. Properties of wild-type, C-terminally truncated, and chimeric maedi-visna virus glycoprotein and putative pseudotyping of retroviral vector particles. J. Virol. 75:548-555.
34. Zeitlin, P. L., L. Lu, J. Rhim, G. Cutting, G. Stetten, K. A. Kieffer, R. Craig, and W. B. Guggino. 1991. A cystic fibrosis bronchial epithelial cell line: immortalization by adeno-12-SV40 infection. Am. J. Respir. Cell Mol. Biol. 4:313-319.