Extracellular calcium sensing promotes human B-cell activation and function

Blood

Volumn 110, Issue 12, 2007, Pages 3985-3995

  Hammond, Caitlin M ^a,b   White, Dionne ^a   Tomic, Jelena ^a,b   Shi, Yonghong ^a   Spaner, David E ^a,b,c  

^a Sunnybrook Health Sciences Centre   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALCIUM; CALCIUM SENSING RECEPTOR; CD38 ANTIGEN; CD86 ANTIGEN; CELL SURFACE PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA; PHOSPHOLIPASE C INHIBITOR; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN KINASE C; TRYPSIN;

ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE ACTIVATION; CALCIUM BLOOD LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CELL FUNCTION; CELL ISOLATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE RELEASE; EXTRACELLULAR CALCIUM; FLOW CYTOMETRY; GENE SEQUENCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOBLOTTING; IMMUNOMODULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 37049033095     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-05-088468     Document Type: Article

References (65)

1. Beaven MA, Rogers J, Moore JP, Hesketh TR, Smith GA, Metcalfe JC. The mechanism of the calcium signal and correlation with histamine release in 2H3 cells. J Biol Chem. 1984;259:7129-7136.
2. Jaffe LF. Calcium explosions as triggers of development. Ann N Y Acad Sci. 1980;339:86-101.
3. Massini P, Naf U. Ca2+ ionophores and the activation of human blood platelets: the effects of ionomycin, beauvericin, lysocellin, virginiamycin S, lasalocid-derivatives and McN 4308. Biochim Biophys Acta. 1980;598:575-587.
4. Rabinovitch PS, June CH, Grossmann A, Ledbetter JA. Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3: simultaneous use of indo-1 and immunofluorescence with flow cytometry. J Immunol. 1986;137:952-961.
5. Imboden JB, Stobo JD. Transmembrane signalling by the T cell antigen receptor: perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores. J Exp Med. 1985;161:446-456.
6. Gelfand EW, Mills GB, Cheung RK, Lee JW, Grinstein S. Transmembrane ion fluxes during activation of human T lymphocytes: role of Ca2+, Na+/H+ exchange and phospholipid turnover. Immunol Rev. 1987;95:59-87.
7. Oettgen HC, Terhorst C, Cantley LC, Rosoff PM. Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx. Cell. 1985;40:583-590.
8. Freedman BD. Mechanisms of calcium signaling and function in lymphocytes. Crit Rev Immunol. 2006;26:97-111.
9. Xiong Z, Lu W, MacDonald JF. Extracellular calcium sensed by a novel cation channel in hippocampal neurons. Proc Natl Acad Sci U S A. 1997;94:7012-7017.
10. Brown EM, MacLeod RJ. Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev. 2001;81:239-297.
11. Kwak JO, Kwak J, Kim HW, et al. The extracellular calcium sensing receptor is expressed in mouse mesangial cells and modulates cell proliferation. Exp Mol Med. 2005;37:457-465.
12. Tu CL, Chang W, Bikle DD. The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes. J Invest Dermatol. 2007;127:1074-1083.
13. Dell'Aquila ME, De Santis T, Cho YS, et al. Localization and quantitative expression of the calcium-sensing receptor protein in human oocytes. Fertil Steril. 2006;85(suppl 1):1240-1247.
14. Ogata S, Kubota Y, Satoh S, et al. Ca2+ stimulates COX-2 expression through calcium-sensing receptor in fibroblasts. Biochem Biophys Res Commun. 2006;351:808-814.
15. Yamaguchi T, Olozak I, Chattopadhyay N, et al. Expression of extracellular calcium (Ca2+o)-sensing receptor in human peripheral blood monocytes. Biochem Biophys Res Commun. 1998;246:501-506.
16. Adams GB, Chabner KT, Alley IR, et al. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature. 2006;439:599-603.
17. Yamaguchi T, Yamauchi M, Sugimoto T, et al. The extracellular calcium Ca2+o-sensing receptor is expressed in myeloma cells and modulates cell proliferation. Biochem Biophys Res Commun. 2002;299:532-538.
18. Spaner DE, Miller RL, Mena J, Grossman L, Sorrenti V, Shi Y. Regression of lymphomatous skin deposits in a chronic lymphocytic leukemia patient treated with the Toll-like receptor-7/8 agonist, imiquimod. Leuk Lymphoma. 2005;46:935-939.
19. Spaner DE, Shi Y, White D, et al. Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cells. Leukemia. 2006;20:286-295.
20. Hammond C, Shi Y, Mena J, et al. Effect of serum and antioxidants on the immunogenicity of protein kinase C-activated chronic lymphocytic leukemia cells. J Immunother. 2005;28:28-39.
21. Frenkel K, Gleichauf C. Hydrogen peroxide formation by cells treated with a tumor promoter. Free Radic Res Commun. 1991;12-13(pt 2):783-794.
22. Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett. 2003;85:85-95.
23. Jambrina E, Alonso R, Alcalde M, et al. Calcium influx through receptor-operated channel induces mitochondria-triggered paraptotic cell death. J Biol Chem. 2003;278:14134-14145.
24. Orrenius S, McConkey DJ, Nicotera P. Role of calcium in toxic and programmed cell death. Adv Exp Med Biol. 1991;283:419-425.
25. Hoth M. Calcium and barium permeation through calcium release-activated calcium (CRAC) channels. Pflugers Arch. 1995;430:315-322.
26. Huang Y, Wange RL. T cell receptor signaling: beyond complex complexes. J Biol Chem. 2004;279:28827-28830.
27. Mason MJ, Mayer B, Hymel LJ. Inhibition of Ca2+ transport pathways in thymic lymphocytes by econazole, miconazole, and SKF 96365. Am J Physiol. 1993;264:C654-C662.
28. McTavish D, Sorkin EM. Verapamil: an updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension. Drugs. 1989;38:19-76.
29. Korchak HM, Corkey BE, Yaney GC, Kilpatrick LE. Negative regulation of ligand-initiated Ca(2+) uptake by PKC-beta II in differentiated HL60 cells. Am J Physiol Cell Physiol. 2001;281:C514-C523.
30. Sengupta TK, Talbot ES, Scherle PA, Ivashkiv LB. Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases. Proc Natl Acad Sci U S A. 1998;95:11107-11112.
31. Chang W, Pratt S, Chen TH, Shoback D. Protein kinase C activation blocks calcium receptor signaling in Xenopus laevis oocytes. Mol Cell Endocrinol. 1999;158:13-23.
32. Dal Porto JM, Gauld SB, Merrell KT, Mills D, Pugh-Bernard AE, Cambier J. B cell antigen receptor signaling 101. Mol Immunol. 2004;41:599-613.
33. Yazawa N, Fujimoto M, Sato S, et al. CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes. Blood. 2003;102:1374-1380.
34. Mitra SK, Schlaepfer DD. Integrin-regulated FAKSrc signaling in normal and cancer cells. Curr Opin Cell Biol. 2006;18:516-523.
35. Lai JY, Cox PJ, Patel R, et al. Potent small molecule inhibitors of spleen tyrosine kinase (Syk). Bioorg Med Chem Lett. 2003;13:3111-3114.
36. Monroe JGITAM-mediated tonic signalling through pre-BCR and BCR complexes. Nat Rev Immunol. 2006;6:283-294.
37. Fasano M, Curry S, Terreno E, et al. The extraordinary ligand binding properties of human serum albumin. IUBMB Life. 2005;57:787-796.
38. Kragh-Hansen U. Molecular aspects of ligand binding to serum albumin. Pharmacol Rev. 1981;33:17-53.
39. Peters T Jr, ed. All About Albumin: Biochemistry, Genetics and Medical Applications. San Diego, CA: Academic Press; 1996.
40. Berchtold S, Muhl-Zurbes P, Maczek E, Golka A, Schuler G, Steinkasserer A. Cloning and characterization of the promoter region of the human CD83 gene. Immunobiology. 2002;205:231-246.
41. Natarajan K, Singh S, Burke TR Jr, Grunberger D, Aggarwal BB. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B. Proc Natl Acad Sci U S A. 1996;93:9090-9095.
42. Pierce JW, Schoenleber R, Jesmok G, et al. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem. 1997;272:21096-21103.
43. Kobori M, Yang Z, Gong D, et al. Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex. Cell Death Differ. 2004;11:123-130.
44. Cons BM, Fox KR. Effects of the antitumor antibiotic mithramycin on the structure of repetitive DNA regions adjacent to its GC-rich binding site. Biochemistry. 1991;30:6314-6321.
45. Sakai H, Jinawath A, Yamaoka S, Yuasa Y. Upregulation of MUC6 mucin gene expression by NFkappaB and Sp factors. Biochem Biophys Res Commun. 2005;333:1254-1260.
46. Shishodia S, Aggarwal BB. Nuclear factor-kappaB activation: a question of life or death. J Biochem Mol Biol. 2002;35:28-40.
47. Tomic J, White D, Shi Y, et al. Sensitization of IL-2 signaling through TLR-7 enhances B lymphoma cell immunogenicity. J Immunol. 2006;176:3830-3839.
48. Suzuki Y, Ono Y. Involvement of reactive oxygen species produced via NADPH oxidase in tyrosine phosphorylation in human B- and T-lineage lymphoid cells. Biochem Biophys Res Commun. 1999;255:262-267.
49. Di Pucchio T, Lapenta C, Santini SM, Logozzi M, Parlato S, Belardelli F. CD2+/CD14+ monocytes rapidly differentiate into CD83+ dendritic cells. Eur J Immunol. 2003;33:358-367.
50. Donnadieu E, Bismuth G, Trautmann A. Calcium fluxes in T lymphocytes. J Biol Chem. 1992;267:25864-25872.
51. Brown EM. The extracellular Ca2+-sensing receptor: central mediator of systemic calcium homeostasis. Annu Rev Nutr. 2000;20:507-533.
52. Owen CS, Dever S. Indo-1 can simultaneously detect Ba2+ entry and Ca2+ blockade at a plasma membrane calcium channel. Mol Cell Biochem. 1995;151:91-98.
53. Vermeulen L, De Wilde G, Van Damme P, Vanden Berghe W, Haegeman G. Transcriptional activation of the NF-kappaB p65 subunit by mitogen-and stress-activated protein kinase-1 (MSK1). EMBO J. 2003;22:1313-1324.
54. Kane LP, Shapiro VS, Stokoe D, Weiss A. Induction of NF-kappaB by the Akt/PKB kinase. Curr Biol. 1999;9:601-604.
55. Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature. 1999;401:82-85.
56. Madrid LV, Wang CY, Guttridge DC, Schottelius AJ, Baldwin AS Jr, Mayo MW. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Mol Cell Biol. 2000;20:1626-1638.
57. Sizemore N, Leung S, Stark GR. Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit. Mol Cell Biol. 1999;19:4798-4805.
58. Bauer B, Baier G. Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration. Mol Immunol. 2002;38:1087-1099.
59. Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol. 2003;4:517-529.
60. Erstad BL, Richards H, Rose S, Nakazato P, Fortune J. Influence of twenty-five per cent human serum albumin on total and ionized calcium concentrations in vivo. Crit Care. 1999;3:117-121.
61. Weaver C, Heaney R. Calcium in human health. Totowa, NJ: Humana Press; 2006.
62. Whitfield J, Chakravarthy B. Calcium: the grandmaster cell signaler. Ottawa, ON: NRC Research Press; 2001.
63. Kaslick RS, Chasens AI, Mandel ID, et al. Quantitative analysis of sodium, potassium and calcium in gingival fluid from gingiva in varying degrees of inflammation. J Periodontol. 1970;41:93-97.
64. Lin CY, Huang TP. Enhancement of ionized calcium and 1,25- dihydroxycholecalciferol loss from peritoneal fluid during peritonitis in patients treated with continuous ambulatory peritoneal dialysis. Nephron. 1991;59:90-95.
65. Menkin V. Biochemical Mechanisms in Inflammation. Chicago, IL: Charles Thomas Publisher; 1981.