Synthesis of some epoxy and/or N-oxy 17-picolyl and 17-picolinylidene-androst-5-ene derivatives and evaluation of their biological activity

Steroids

Volumn 73, Issue 1, 2008, Pages 129-138

  Djurendić, Evgenija ^a   Daljev, Jovana ^a   Sakač, Marija ^a   Čanadi, Janoš ^a   Šanta, Suzana Jovanović ^a   Andrić, Silvana ^a   Klisurić, Olivera ^a   Kojić, Vesna ^b   Bogdanović, Gordana ^b   Djurendić Brenesel, Maja ^a   Novaković, Sladjana ^c   Gaši, Katarina Penov ^a  

^a UNIVERSITY OF NOVI SAD   (Serbia)

^b ONCOLOGY INSTITUTE OF VOJVODINA   (Serbia)

^c UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Androst 5 ene derivatives; Antitumor activity; Aromatase inhibition; Epoxidation; Picolyl and picolinylidene derivatives; X ray analysis

Indexed keywords

17 PICOLINYLIDENE N OXIDE; 17 PICOLINYLIDENEANDROST 4 EN 3 ONE N OXIDE; 3 CHLOROPERBENZOIC ACID; 3BETA ACETOXY 17 PICOLINYLIDENEANDROST 5 ENE; 3BETA ACETOXY 17 PICOLINYLIDENEANDROST 5 ENE N OXIDE; 3BETA HYDROXY 17 PICOLINYLIDENEANDROST 5 ENE; 3BETA,17BETA DIHYDROXY 17ALPHA PICOLYLANDROST 5 ENE; 4BETA,5BETA EPOXY 17BETA HYDROXY 17ALPHA PICOLYLANDROSTANE 3 ONE; 5ALPHA,6ALPHA EPOXY 17 PICOLINYLIDENE; 5ALPHA,6ALPHA EPOXY 17 PICOLINYLIDENE N OXIDE; 5ALPHA,6ALPHA:17ALPHA,20ALPHA DIEPOXY N OXIDE; 5BETA,6BETA EPOXY 17 PICOLINYLIDENE; 5BETA,6BETA EPOXY 17 PICOLINYLIDENE N OXIDE; 5BETA,6BETA:17ALPHA,20ALPHA DIEPOXY N OXIDE; ANDROSTANE DERIVATIVE; AROMATASE; EPOXIDE; ESTROGEN RECEPTOR; HYDROGEN PEROXIDE; STEROID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN MCF 7; CULTURE MEDIUM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; OPPENAUER OXIDATION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STRUCTURE ANALYSIS; X RAY ANALYSIS; X RAY CRYSTALLOGRAPHY;

ANDROSTENES; ANIMALS; AROMATASE; AROMATASE INHIBITORS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; CHLOROBENZOATES; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; MOLECULAR STRUCTURE; OVARY; RATS;

EID: 37049028370     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2007.09.005     Document Type: Article

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