메뉴 건너뛰기




Volumn 61, Issue 3-6, 1997, Pages 241-245

Clinical use of aromatase inhibitors in the treatment of advanced breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLUTETHIMIDE; AROMATASE INHIBITOR; ESTROGEN; FADROZOLE; FORMESTANE; LETROZOLE; MEGESTROL; TAMOXIFEN;

EID: 0031123310     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(96)00249-X     Document Type: Conference Paper
Times cited : (17)

References (36)
  • 2
    • 0017283332 scopus 로고
    • Oestradiol synthesis from C19 steroids by human breast cancers
    • Miller W.R., Forrest A.P.M. Oestradiol synthesis from C19 steroids by human breast cancers. Br. J. Cancer. 33:1976;116-118.
    • (1976) Br. J. Cancer , vol.33 , pp. 116-118
    • Miller, W.R.1    Forrest, A.P.M.2
  • 4
    • 0024595623 scopus 로고
    • Dose-related endocrine effects and pharmacokinetics of oral and intramuscular 4-hydroxyandrostenedione in postmenopausal breast cancer patients
    • Dowsett M., Cunningham D.C., Stein R.C., Evan S., Dehennin L., Hedley A., Coombes R.C. Dose-related endocrine effects and pharmacokinetics of oral and intramuscular 4-hydroxyandrostenedione in postmenopausal breast cancer patients. Cancer Res. 49:1989;1306-1312.
    • (1989) Cancer Res. , vol.49 , pp. 1306-1312
    • Dowsett, M.1    Cunningham, D.C.2    Stein, R.C.3    Evan, S.4    Dehennin, L.5    Hedley, A.6    Coombes, R.C.7
  • 5
    • 0025237867 scopus 로고
    • Aromatase inhibition with 4-hydroxyandrostenedione in the treatment of postmenopausal patients with advanced breast cancer: Phase II study
    • Höffken K., Jonat W., Possinger K., Kolbel M., Kunz T.H., Wagner H., Becher R., Callies R., Schmidt C.G. Aromatase inhibition with 4-hydroxyandrostenedione in the treatment of postmenopausal patients with advanced breast cancer: phase II study. J. Clin. Oncol. 8:1990;875-880.
    • (1990) J. Clin. Oncol. , vol.8 , pp. 875-880
    • Höffken, K.1    Jonat, W.2    Possinger, K.3    Kolbel, M.4    Kunz, T.H.5    Wagner, H.6    Becher, R.7    Callies, R.8    Schmidt, C.G.9
  • 7
    • 0026666565 scopus 로고
    • 4-Hydroxyandrostenedione: A new treatment for postmenopausal patients with breast cancer
    • Coombes R.C., Hughes S.W.M., Dowsett M. 4-Hydroxyandrostenedione: a new treatment for postmenopausal patients with breast cancer. Eur. J. Cancer. 28A:1992;1941-1945.
    • (1992) Eur. J. Cancer , vol.28 , pp. 1941-1945
    • Coombes, R.C.1    Hughes, S.W.M.2    Dowsett, M.3
  • 8
    • 0027403032 scopus 로고
    • Formestane: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of breast cancer and prostatic cancer
    • Wiseman L.R., McTavish D. Formestane: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of breast cancer and prostatic cancer. Drugs. 45:1993;66-84.
    • (1993) Drugs , vol.45 , pp. 66-84
    • Wiseman, L.R.1    McTavish, D.2
  • 11
    • 0023517368 scopus 로고
    • In-vitro and in-vivo studies demonstrating potent and selective oestrogen inhibition with the non-steroidal aromatase inhibitor CGS 16949 A
    • Steele R.E., Mellor L.B., Sawyer W.K., Wasvary J.M., Browne L.J. In-vitro and in-vivo studies demonstrating potent and selective oestrogen inhibition with the non-steroidal aromatase inhibitor CGS 16949 A. Steroids. 50:1987;147-161.
    • (1987) Steroids , vol.50 , pp. 147-161
    • Steele, R.E.1    Mellor, L.B.2    Sawyer, W.K.3    Wasvary, J.M.4    Browne, L.J.5
  • 13
    • 0025327094 scopus 로고
    • Potency and selectivity of the non-steroidal aromatase inhibitor CGS 16949A in postmenopausal breast cancer patients
    • Dowsett M., Stein R.C., Metha A., Coombes R.C. Potency and selectivity of the non-steroidal aromatase inhibitor CGS 16949A in postmenopausal breast cancer patients. Clin. Endocr. 32:1990;623-634.
    • (1990) Clin. Endocr. , vol.32 , pp. 623-634
    • Dowsett, M.1    Stein, R.C.2    Metha, A.3    Coombes, R.C.4
  • 17
    • 0026544537 scopus 로고
    • A study of fadrozole, a new aromatase inhibitor, in postmenopausal women with advanced metastatic breast cancer
    • Raats J.I., Falkson G., Falkson H.C. A study of fadrozole, a new aromatase inhibitor, in postmenopausal women with advanced metastatic breast cancer. J. Clin. Oncol. 10:1992;111-116.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 111-116
    • Raats, J.I.1    Falkson, G.2    Falkson, H.C.3
  • 19
    • 0025274853 scopus 로고
    • Preliminary study of the treatment of advanced breast cancer in postmenopausal women with the aromatase inhibitor CGS 16949A
    • Stein R.C., Dowsett M., Davenport J., Hedley A., Ford H.T., Gazet J.C., Coombes R.C. Preliminary study of the treatment of advanced breast cancer in postmenopausal women with the aromatase inhibitor CGS 16949A. Cancer Res. 50:1990;1381-1384.
    • (1990) Cancer Res. , vol.50 , pp. 1381-1384
    • Stein, R.C.1    Dowsett, M.2    Davenport, J.3    Hedley, A.4    Ford, H.T.5    Gazet, J.C.6    Coombes, R.C.7
  • 21
    • 0025793984 scopus 로고
    • The influence of CGS 16949A on peripheral aromatisation in breast cancer patients
    • Lønning P.E., Jacobs S., Jones A., Haynes B., Powles T., Dowsett M. The influence of CGS 16949A on peripheral aromatisation in breast cancer patients. Br. J. Cancer. 63:1991;789-793.
    • (1991) Br. J. Cancer , vol.63 , pp. 789-793
    • Lønning, P.E.1    Jacobs, S.2    Jones, A.3    Haynes, B.4    Powles, T.5    Dowsett, M.6
  • 22
    • 0029940269 scopus 로고    scopus 로고
    • Fadrozole HCl (CGS 16949A) versus megestrol acetate treatment of postmenopausal patients with metastatic breast carcinoma. Results of two randomized double blind controlled multi-institutional trials
    • for the Multi-Institutional Trialist Collaborative Study Group
    • Buzdar A.U., Smith R., Vogel Bonomi P., Keller A.M., Favis G., Mulagha M., Cooper J. Fadrozole HCl (CGS 16949A) versus megestrol acetate treatment of postmenopausal patients with metastatic breast carcinoma. Results of two randomized double blind controlled multi-institutional trials. for the Multi-Institutional Trialist Collaborative Study Group Cancer. 77:1996;2503-2513.
    • (1996) Cancer , vol.77 , pp. 2503-2513
    • Buzdar, A.U.1    Smith, R.2    Vogel Bonomi, P.3    Keller, A.M.4    Favis, G.5    Mulagha, M.6    Cooper, J.7
  • 23
    • 0025697212 scopus 로고
    • Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor
    • Bhatnagar A.S., Häusler A., Schieweck K., Lang M., Browman R. Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor. J. Steroid Biochem. Molec. Biol. 37:1990;1021-1027.
    • (1990) J. Steroid Biochem. Molec. Biol. , vol.37 , pp. 1021-1027
    • Bhatnagar, A.S.1    Häusler, A.2    Schieweck, K.3    Lang, M.4    Browman, R.5
  • 24
    • 0025677316 scopus 로고
    • Inhibition of aromatase in vitro and in vivo by aromatase inhibitors
    • Bhatnagar A.S., Häusler A., Schieweck K. Inhibition of aromatase in vitro and in vivo by aromatase inhibitors. J. Enzyme Inhib. 4:1990;179-186.
    • (1990) J. Enzyme Inhib. , vol.4 , pp. 179-186
    • Bhatnagar, A.S.1    Häusler, A.2    Schieweck, K.3
  • 25
    • 0027183969 scopus 로고
    • Open dose-finding study of a new potent and selective nonsteroidal aromatase inhibitor, CGS 20267, in healthy male subjects
    • Trunet P.F., Mueller Ph., Bhatnagar A.S., Dickes I., Monnet G., White G. Open dose-finding study of a new potent and selective nonsteroidal aromatase inhibitor, CGS 20267, in healthy male subjects. J. Clin. Endocr. Metab. 77:1993;319-323.
    • (1993) J. Clin. Endocr. Metab. , vol.77 , pp. 319-323
    • Trunet, P.F.1    Mueller, Ph.2    Bhatnagar, A.S.3    Dickes, I.4    Monnet, G.5    White, G.6
  • 28
    • 0027535830 scopus 로고
    • Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer
    • Iveson T.J., Smith I.E., Ahern J., Smithers D.A., Trunet P.F., Dowsett M. Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer. Cancer Res. 53:1993;266-270.
    • (1993) Cancer Res. , vol.53 , pp. 266-270
    • Iveson, T.J.1    Smith, I.E.2    Ahern, J.3    Smithers, D.A.4    Trunet, P.F.5    Dowsett, M.6
  • 30
    • 0029560237 scopus 로고
    • In vivo measurement of aromatase inhibition by letrozole (CGS 20267) in postmenopausal patients with advanced breast cancer
    • Dowsett M., Jones A., Johnston S.R.D., Jacobs S., Trunet P.F., Smith I.E. In vivo measurement of aromatase inhibition by letrozole (CGS 20267) in postmenopausal patients with advanced breast cancer. Clin. Cancer Res. 1:1995;1511-1515.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 1511-1515
    • Dowsett, M.1    Jones, A.2    Johnston, S.R.D.3    Jacobs, S.4    Trunet, P.F.5    Smith, I.E.6
  • 31
    • 0030065503 scopus 로고    scopus 로고
    • Letrozole, a new oral nonsteroidal aromatase inhibitor in treating postmenopausal patients with advanced breast cancer
    • Bisagni G., Cocconi G., Scaglione F., Fraschini F., Pfister Ch., Trunet P.F. Letrozole, a new oral nonsteroidal aromatase inhibitor in treating postmenopausal patients with advanced breast cancer. A pilot study. Ann. Oncol. 7:1996;99-102.
    • (1996) A Pilot Study. Ann. Oncol. , vol.7 , pp. 99-102
    • Bisagni, G.1    Cocconi, G.2    Scaglione, F.3    Fraschini, F.4    Pfister, Ch.5    Trunet, P.F.6
  • 32
    • 0000499356 scopus 로고
    • Phase II trial of letrozole (a novel oral nonsteroidal aromatase inhibitor) in postmenopausal patients with advanced or recurrent breast cancer
    • Tominaga T., Ohashi Y., Abe R., Yoshida M., Koyama H., Nomura Y., Bhatnagar A.S. Phase II trial of letrozole (a novel oral nonsteroidal aromatase inhibitor) in postmenopausal patients with advanced or recurrent breast cancer. Eur. J. Cancer. 31A:1995;S81.
    • (1995) Eur. J. Cancer , vol.31 , pp. 81
    • Tominaga, T.1    Ohashi, Y.2    Abe, R.3    Yoshida, M.4    Koyama, H.5    Nomura, Y.6    Bhatnagar, A.S.7
  • 33
    • 0001170654 scopus 로고    scopus 로고
    • Double-blind trial in postmenopausal women with advanced breast cancer showing a dose-effect and superiority of 2.5 mg letrozole over megestrol acetate (abstract 64)
    • for the Letrozole International Trial Group (AR/BC2). Philadelphia
    • Dombernowsky P., Smith I., Falkson G., Leonard R., Panasci L., Bellmunt J., Bezwoda W., Gardin G., Gudgeon A., Chaudri H.A., Hornberger U. Double-blind trial in postmenopausal women with advanced breast cancer showing a dose-effect and superiority of 2.5 mg letrozole over megestrol acetate (abstract 64). for the Letrozole International Trial Group (AR/BC2) Philadelphia Proceedings of ASCO. 1996;100.
    • (1996) Proceedings of ASCO , pp. 100
    • Dombernowsky, P.1    Smith, I.2    Falkson, G.3    Leonard, R.4    Panasci, L.5    Bellmunt, J.6    Bezwoda, W.7    Gardin, G.8    Gudgeon, A.9    Chaudri, H.A.10    Hornberger, U.11
  • 34
    • 0024235959 scopus 로고
    • Endocrine therapy of advanced breast cancer
    • Rose C., Mouridsen H.T. Endocrine therapy of advanced breast cancer. Acta Oncol. 27:1988;721-728.
    • (1988) Acta Oncol. , vol.27 , pp. 721-728
    • Rose, C.1    Mouridsen, H.T.2
  • 35
    • 9244245282 scopus 로고    scopus 로고
    • A randomized trial comparing two doses of the new selective aromatase inhibitor anastrozole (Arimidex®) with megestrol acetate in postmenopausal women with advanced breast cancer
    • on behalf of the Arimidex Study Group
    • Jonat W., Howell A., Blomqvist Eiermann W., Winblad G., Tyrell C., Mauriac L., Roche H., Lundgren S., Hellmund R., Azab M. A randomized trial comparing two doses of the new selective aromatase inhibitor anastrozole (Arimidex®) with megestrol acetate in postmenopausal women with advanced breast cancer. on behalf of the Arimidex Study Group Eur. J. Cancer. 32A:1996;404-412.
    • (1996) Eur. J. Cancer , vol.32 , pp. 404-412
    • Jonat, W.1    Howell, A.2    Blomqvist Eiermann, W.3    Winblad, G.4    Tyrell, C.5    Mauriac, L.6    Roche, H.7    Lundgren, S.8    Hellmund, R.9    Azab, M.10
  • 36
    • 0027169676 scopus 로고
    • Editorial: Estrogen synthesis inhibitors: From "off the rack" to haute couture
    • Santen R.J. Editorial: estrogen synthesis inhibitors: from "off the rack" to haute couture. J. Clin. Endocr. Metab. 77:1993;316-318.
    • (1993) J. Clin. Endocr. Metab. , vol.77 , pp. 316-318
    • Santen, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.