Study on the molecular mechanism of inhibiting HIV-1 integrase by EBR28 peptide via molecular modeling approach

Biophysical Chemistry

Volumn 132, Issue 2-3, 2008, Pages 69-80

  Hu, Jian Ping ^a,b   Gong, Xin Qi ^a   Su, Ji Guo ^a,c   Chen, Wei Zu ^a   Wang, Cun Xin ^a  

^a BEIJING UNIVERSITY OF TECHNOLOGY   (China)

^b LESHAN NORMAL UNIVERSITY   (China)

^c YANSHAN UNIVERSITY   (China)

Author keywords

EBR28 peptide; Essential dynamics; Inhibition mechanism; Integrase; MM GBSA model; Molecular dynamics simulation

Indexed keywords

INTEGRASE; PROTEIN EBR28; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN STRUCTURE;

BINDING SITES; COMPUTER SIMULATION; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; MODELS, CHEMICAL; OLIGOPEPTIDES; PROTEIN BINDING;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 37049001192     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2007.09.008     Document Type: Article

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