Death-resistant and nonresistant malignant human cell lines under anoxia in vitro

International Journal of Clinical Oncology

Volumn 12, Issue 6, 2007, Pages 455-462

  Yasuda, Megumi ^a   Matsubara, Junko ^b   Yamasaki, Harufumi ^a   Fujita, Yoshihiko ^a   Konishi, Hiroyoshi ^a   Koinuma, Satoshi ^a   Taketani, Shigeru ^b   Horiuchi, Yoshitaka ^a   Utsumi, Hiroshi ^c   Yasuda, Yoshiko ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^c HEALTH RESEARCH FOUNDATION   (Japan)

Author keywords

Anaerobic glycolysis; Bcl 2 family; Cancer cell lines; HIF 1 ; Survival under anoxia

Indexed keywords

ADENOSINE TRIPHOSPHATE; ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTIC ACID; PROTEIN BCL 2;

ANOXIA; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER RESISTANCE; CELL LEVEL; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; MALIGNANT NEOPLASTIC DISEASE; MICROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANOXIA; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; ERYTHROPOIETIN; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-2; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT;

EID: 36949004492     PISSN: 13419625     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10147-007-0714-6     Document Type: Article

References (28)

1. GL Semenza 1998 Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis J Lab Clin Med 131 207 214
2. LE Huang Z Arany DM Livingston 1996 Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit J Biol Chem 271 32253 32259
3. CW Pugh JF O'Rourke M Nagao 1997 Activation of hypoxia-inducible factor-1; definition of regulatory domains within the α subunit J Biol Chem 272 11205 11214
4. HF Bunn RO Poyton 1996 Oxygen sensing and molecular adaptation to hypoxia Physiol Rev 76 839 885
5. S Salceda J Caro 1997 Hypoxia inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes J Biol Chem 272 22642 22647
6. GL Semenza MK Nejfelt SM Chi 1991 Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene Proc Natl Acad Sci USA 88 5680 5684
7. I Beck S Ramirez R Weinmann 1991 Enhancer element at the 3′-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene J Biol Chem 266 15563 15566
8. A Minchenko S Salceda T Bauer 1994 Hypoxia regulatory elements of the human vascular endothelial growth factor gene Cell Mol Biol Res 40 35 39
9. 2 homeostasis by hypoxia-inducible factor 1α Genes Dev 12 149 162
10. 2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation Nat Med 3 177 182
11. LV Dang GL Semenza 1999 Oncogenic alterations of metabolism Trends Biochem Sci 24 68 72
12. 2 tension Am J Physiol Cell Physiol 271 C1172 C1180
13. C Schroedl DS McClintock GR Budinger 2002 Hypoxic but not anoxic stabilization of HIF-1α requires mitochondrial reactive oxygen species Am J Physiol Lung Cell Mol Physiol 283 L922 L931
14. TN Seagroves HE Ryan H Lu 2001 Transcription factor HIF-1 is a necessary mediator of the Pasteur effect in mammalian cells Mol Cell Biol 21 3436 3444
15. PH Maxwell GU Dachs JM Gleadle 1997 Hypoxia inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth Proc Natl Acad Sci USA 94 8104 8109
16. P Carmeliet Y Dor JM Herbert 1998 Role of HIF-α in hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis Nature 394 485 490
17. HE Ryan M Poloni W McNulty 2000 Hypoxia-inducible factor-1α is a positive factor in solid tumor growth Cancer Res 60 4010 4015
18. TG Graeber C Osmanian T Jacks 1996 Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours Nature 379 88 91
19. GT Williams CA Smith 1993 Molecular regulation of apoptosis: genetic controls on cell death Cell 74 777 779
20. JC Read 1994 Bcl-2 and the regulation of programmed cell death J Cell Biol 124 1 6
21. AH Wyllie 1995 The genetic regulation of apoptosis Curr Opin Genet Dev 5 97 104
22. JC Martinou DR Green 2001 Breaking the mitochondrial barrier Nature Rev Mol Cell Biol 2 63 67
23. S Desagher JC Martinou 2000 Mitochondria as the central control point of apoptosis Trends Cell Biol 10 369 377
24. D Perez E White 2000 TNF-α signals apoptosis through a bid-dependent conformational change in Bax that is inhibited by E1B 19K Molecular Cell 6 53 63
25. Y Yasuda Y Fujita T Matsuo 2003 Erythropoietin regulates tumour growth of human malignancies Carcinogenesis 24 1021 1029
26. JP Kaltenbach MH Kaltenbach WB Lyons 1958 Nigrosin as a dye for differentiating live and dead ascites cells Exp Cell Res 15 112 117
27. M Koritzinsky MG Magagnin T van den Beucken 2006 Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control EMBO J 25 1114 1125
28. ZN Oltvai CL Milliman SJ Korsmeyer 1993 Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 74 609 619