Association of cumulative cyclosporine dose with its irreversible nephrotoxicity in Japanese patients with pediatric-onset autoimmune diseases

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 12, 2007, Pages 2371-2375

  Nakamura, Tsutomu ^a   Nozu, Kandai ^b   Iijima, Kazumoto ^c   Yoshikawa, Norishige ^d   Moriya, Yuka ^a   Yamamori, Motohiro ^a   Kako, Asae ^a   Matsuo, Masafumi ^b   Sakurai, Aki ^e   Okamura, Noboru ^b   Ishikawa, Toshihisa ^e   Okumura, Katsuhiko ^a,b   Sakaeda, Toshiyuki ^a,f  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^d WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^e TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^f KYOTO UNIVERSITY   (Japan)

Author keywords

Auto immune disease; Cyclosporine; Nephrotoxicity; Pediatric patient

Indexed keywords

CYCLOSPORIN A; NIFEDIPINE; PREDNISOLONE;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNE DISEASE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; FEMALE; HISTOLOGY; HUMAN; JAPANESE; MAINTENANCE DRUG DOSE; MALE; MICROEMULSION; NEPHROTIC SYNDROME; NEPHROTOXICITY; PROBABILITY; RISK FACTOR; SINGLE DRUG DOSE; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT DURATION;

AREA UNDER CURVE; AUTOIMMUNE DISEASES; CHILD; CYCLOSPORINE; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENOTYPE; HALF-LIFE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; JAPAN; KIDNEY; KIDNEY DISEASES; MALE; P-GLYCOPROTEIN;

EID: 36848999783     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.2371     Document Type: Article

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