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Volumn 18, Issue 12, 2007, Pages 3089-3100

PPARα protects proximal tubular cells from acute fatty acid toxicity

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; FATTY ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN; MESSENGER RNA;

EID: 36848998955     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2007020238     Document Type: Article
Times cited : (63)

References (47)
  • 1
    • 0032757381 scopus 로고    scopus 로고
    • Tubulointerstitum as predictor of progression of glomerular diseases
    • D'Amico G: Tubulointerstitum as predictor of progression of glomerular diseases. Nephron 83: 289-295, 1999
    • (1999) Nephron , vol.83 , pp. 289-295
    • D'Amico, G.1
  • 2
    • 0032512094 scopus 로고    scopus 로고
    • Pathophysiology of progressive nephropathies
    • Remuzzi G, Bertani T: Pathophysiology of progressive nephropathies. N Engl J Med 339: 1448-1456, 1998
    • (1998) N Engl J Med , vol.339 , pp. 1448-1456
    • Remuzzi, G.1    Bertani, T.2
  • 5
    • 0037324549 scopus 로고    scopus 로고
    • Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo
    • Tang S, Leung JC, Abe K, Chan KW, Chan LY, Chan TM, Lai KN: Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo. J Clin Invest 111: 515-527, 2003
    • (2003) J Clin Invest , vol.111 , pp. 515-527
    • Tang, S.1    Leung, J.C.2    Abe, K.3    Chan, K.W.4    Chan, L.Y.5    Chan, T.M.6    Lai, K.N.7
  • 6
    • 0031975395 scopus 로고    scopus 로고
    • Toxicity of holotransferrin but not albumin in proximal tubule cells in primary culture
    • Chen L, Boadle RA, Harris DC: Toxicity of holotransferrin but not albumin in proximal tubule cells in primary culture. J Am Soc Nephrol 9: 77-84, 1998
    • (1998) J Am Soc Nephrol , vol.9 , pp. 77-84
    • Chen, L.1    Boadle, R.A.2    Harris, D.C.3
  • 7
    • 0032711255 scopus 로고    scopus 로고
    • Complement membrane attack complex (C5b-9) mediates interstitial disease in experimental nephrotic syndrome
    • Nangaku M, Pippin J, Couser WG: Complement membrane attack complex (C5b-9) mediates interstitial disease in experimental nephrotic syndrome. J Am Soc Nephrol 10: 2323-2331, 1999
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2323-2331
    • Nangaku, M.1    Pippin, J.2    Couser, W.G.3
  • 8
    • 0028205615 scopus 로고
    • Tubular lipidosis: Epiphenomenon or pathogenetic lesion in human renal disease?
    • Ong AC, Moorhead JF: Tubular lipidosis: Epiphenomenon or pathogenetic lesion in human renal disease? Kidney Int 45: 753-762, 1994
    • (1994) Kidney Int , vol.45 , pp. 753-762
    • Ong, A.C.1    Moorhead, J.F.2
  • 9
    • 0027947379 scopus 로고
    • Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-beta-cell relationships
    • Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, Unger RH: Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci U S A 91: 10878-10882, 1994
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10878-10882
    • Lee, Y.1    Hirose, H.2    Ohneda, M.3    Johnson, J.H.4    McGarry, J.D.5    Unger, R.H.6
  • 11
    • 0032478314 scopus 로고    scopus 로고
    • Fatty acid-induced beta cell apoptosis: A link between obesity and diabetes
    • Shimabukuro M, Zhou YT, Levi M, Unger RH: Fatty acid-induced beta cell apoptosis: A link between obesity and diabetes. Proc Natl Acad Sci U S A 95: 2498-2502, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 2498-2502
    • Shimabukuro, M.1    Zhou, Y.T.2    Levi, M.3    Unger, R.H.4
  • 12
    • 0035805629 scopus 로고    scopus 로고
    • Palmitate-induced apoptosis can occur through a ceramide-independent pathway
    • Listenberger LL, Ory DS, Schaffer JE: Palmitate-induced apoptosis can occur through a ceramide-independent pathway. J Biol Chem 276: 14890-14895, 2001
    • (2001) J Biol Chem , vol.276 , pp. 14890-14895
    • Listenberger, L.L.1    Ory, D.S.2    Schaffer, J.E.3
  • 13
    • 0032489437 scopus 로고    scopus 로고
    • Altered constitutive expression of fatty acid-metabolising enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)
    • Aoyama T, Peters JM, Iritani N, Nakajima T, Furihata K, Hashimoto T, Gonzalez FJ: Altered constitutive expression of fatty acid-metabolising enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem 273: 5678-5684, 1998
    • (1998) J Biol Chem , vol.273 , pp. 5678-5684
    • Aoyama, T.1    Peters, J.M.2    Iritani, N.3    Nakajima, T.4    Furihata, K.5    Hashimoto, T.6    Gonzalez, F.J.7
  • 15
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, -gamma in the adult rat
    • Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W: Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, -gamma in the adult rat. Endocrinology 137: 354-366, 1996
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 17
    • 0031781381 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor α in altered cell cycle regulation in mouse liver
    • Peters JM, Aoyama T, Cattley RC, Usuda N, Hashimoto T, Gonzalez FJ: Role of peroxisome proliferator-activated receptor α in altered cell cycle regulation in mouse liver. Carcinogenesis 19: 1989-1994, 1998
    • (1998) Carcinogenesis , vol.19 , pp. 1989-1994
    • Peters, J.M.1    Aoyama, T.2    Cattley, R.C.3    Usuda, N.4    Hashimoto, T.5    Gonzalez, F.J.6
  • 18
    • 0034965596 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in inflammation control
    • Delerive P, Fruchart JC, Staels B: Peroxisome proliferator-activated receptors in inflammation control. J Endocrinol 169: 453-459, 2001
    • (2001) J Endocrinol , vol.169 , pp. 453-459
    • Delerive, P.1    Fruchart, J.C.2    Staels, B.3
  • 21
    • 0033305516 scopus 로고    scopus 로고
    • Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro
    • Carlsson C, Borg LA, Welsh N: Sodium palmitate induces partial mitochondrial uncoupling and reactive oxygen species in rat pancreatic islets in vitro. Endocrinology 140: 3422-3428, 1999
    • (1999) Endocrinology , vol.140 , pp. 3422-3428
    • Carlsson, C.1    Borg, L.A.2    Welsh, N.3
  • 22
    • 9244231766 scopus 로고    scopus 로고
    • Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress
    • Kharroubi I, Ladriere L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL: Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress. Endocrinology 145: 5087-5096, 2004
    • (2004) Endocrinology , vol.145 , pp. 5087-5096
    • Kharroubi, I.1    Ladriere, L.2    Cardozo, A.K.3    Dogusan, Z.4    Cnop, M.5    Eizirik, D.L.6
  • 24
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W: Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 103: 1489-1498, 1999
    • (1999) J Clin Invest , vol.103 , pp. 1489-1498
    • Kersten, S.1    Seydoux, J.2    Peters, J.M.3    Gonzalez, F.J.4    Desvergne, B.5    Wahli, W.6
  • 25
    • 2542593338 scopus 로고    scopus 로고
    • Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes
    • Schrauwen P, Hesselink MK: Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes. Diabetes 53: 1412-1417, 2004
    • (2004) Diabetes , vol.53 , pp. 1412-1417
    • Schrauwen, P.1    Hesselink, M.K.2
  • 26
    • 0027327053 scopus 로고
    • Significance of cytoplasmic fatty acid-binding protein for the ischemic heart
    • Glatz JF, Vork MM, van der Vusse GJ: Significance of cytoplasmic fatty acid-binding protein for the ischemic heart. Mol Cell Biochem 123: 167-173, 1993
    • (1993) Mol Cell Biochem , vol.123 , pp. 167-173
    • Glatz, J.F.1    Vork, M.M.2    van der Vusse, G.J.3
  • 27
    • 0032557156 scopus 로고    scopus 로고
    • Physiological properties and functions of intra-cellular fatty acid-binding proteins
    • Coe NR, Bernlohr DA: Physiological properties and functions of intra-cellular fatty acid-binding proteins. Biochim Biophys Acta 1391: 287-306, 1998
    • (1998) Biochim Biophys Acta , vol.1391 , pp. 287-306
    • Coe, N.R.1    Bernlohr, D.A.2
  • 30
    • 0036908619 scopus 로고    scopus 로고
    • Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter
    • Girnun GD, Domann FE, Moore SA, Robbins ME: Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter. Mol Endocrinol 16: 2793-2801, 2002
    • (2002) Mol Endocrinol , vol.16 , pp. 2793-2801
    • Girnun, G.D.1    Domann, F.E.2    Moore, S.A.3    Robbins, M.E.4
  • 31
    • 0033008702 scopus 로고    scopus 로고
    • Induction of the rat Cu/Zn superoxide dismutase gene through the peroxisome proliferator-responsive element by arachidonic acid
    • Yoo HY, Chang MS, Rho HM: Induction of the rat Cu/Zn superoxide dismutase gene through the peroxisome proliferator-responsive element by arachidonic acid. Gene 234: 87-91, 1999
    • (1999) Gene , vol.234 , pp. 87-91
    • Yoo, H.Y.1    Chang, M.S.2    Rho, H.M.3
  • 34
    • 0032482988 scopus 로고    scopus 로고
    • Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression
    • Shimabukuro M, Wang MY, Zhou YT, Newgard CB, Unger RH: Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression. Proc Natl Acad Sci U S A 95: 9558-9561, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9558-9561
    • Shimabukuro, M.1    Wang, M.Y.2    Zhou, Y.T.3    Newgard, C.B.4    Unger, R.H.5
  • 35
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC: Mitochondria and apoptosis. Sience 281: 1309-1312, 1998
    • (1998) Sience , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 36
    • 0031819433 scopus 로고    scopus 로고
    • Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha)
    • Roberts RA, James NH, Woodyatt NJ, Macdonald N, Tugwood JD: Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha). Carcinogenesis 19: 43-48, 1998
    • (1998) Carcinogenesis , vol.19 , pp. 43-48
    • Roberts, R.A.1    James, N.H.2    Woodyatt, N.J.3    Macdonald, N.4    Tugwood, J.D.5
  • 37
    • 9644254466 scopus 로고    scopus 로고
    • Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma
    • Arid M, Chana R, Lewington A, Brown J, Brunskill NJ: Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma. J Am Soc Nephrol 14: 17-27, 2003
    • (2003) J Am Soc Nephrol , vol.14 , pp. 17-27
    • Arid, M.1    Chana, R.2    Lewington, A.3    Brown, J.4    Brunskill, N.J.5
  • 38
    • 0026970404 scopus 로고
    • Nuclear factor kappa B: An oxidative stress-responsive transcription factor of eukaryotic cells (a review)
    • Schreck R, Albermann K, Baeuerle PA: Nuclear factor kappa B: An oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Radie Res Commun 17: 221-237, 1992
    • (1992) Free Radie Res Commun , vol.17 , pp. 221-237
    • Schreck, R.1    Albermann, K.2    Baeuerle, P.A.3
  • 39
    • 0036235016 scopus 로고    scopus 로고
    • Protein overload-induced NF-kappaB activation in proximal tubular cells requires H202 through a PKC-dependent pathway
    • Morigi M, Macconi D, Zoja C, Donadelli R, Buelli S, Zanchi C, Ghilardi M, Remuzzi G: Protein overload-induced NF-kappaB activation in proximal tubular cells requires H202 through a PKC-dependent pathway. J Am Soc Nephrol 13: 1179-1189, 2002
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1179-1189
    • Morigi, M.1    Macconi, D.2    Zoja, C.3    Donadelli, R.4    Buelli, S.5    Zanchi, C.6    Ghilardi, M.7    Remuzzi, G.8
  • 41
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Femandez-Salguero PM, Westphal H, Gonzalez FJ: Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15: 3012-3022, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Femandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 42
    • 0018069508 scopus 로고
    • Acyl-Coenzyme A synthetase and fatty acid oxidation in rat liver peroxisomes
    • Shindo Y, Hashimoto T: Acyl-Coenzyme A synthetase and fatty acid oxidation in rat liver peroxisomes. J Biochem 84: 1177-1181, 1978
    • (1978) J Biochem , vol.84 , pp. 1177-1181
    • Shindo, Y.1    Hashimoto, T.2
  • 43
    • 0026518372 scopus 로고
    • Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase
    • Izai K, Uchida Y, Orii T, Yamamoto S, Hashimoto T: Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase. J Biol Chem 267: 1027-1033, 1992
    • (1992) J Biol Chem , vol.267 , pp. 1027-1033
    • Izai, K.1    Uchida, Y.2    Orii, T.3    Yamamoto, S.4    Hashimoto, T.5
  • 44
    • 0026515859 scopus 로고
    • Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein
    • Uchida Y, Izai K, Orii T, Hashimoto T: Novel fatty acid beta-oxidation enzymes in rat liver mitochondria. II. Purification and properties of enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein. J Biol Chem 267: 1034-1041, 1992
    • (1992) J Biol Chem , vol.267 , pp. 1034-1041
    • Uchida, Y.1    Izai, K.2    Orii, T.3    Hashimoto, T.4
  • 45
    • 0018977041 scopus 로고
    • The presence of a new 3-oxoacyl-CoA thiolase in rat liver peroxisomes
    • Miyazawa S, Osumi T, Hashimoto T: The presence of a new 3-oxoacyl-CoA thiolase in rat liver peroxisomes. Eur J Biochem 103: 589-596, 1980
    • (1980) Eur J Biochem , vol.103 , pp. 589-596
    • Miyazawa, S.1    Osumi, T.2    Hashimoto, T.3
  • 46
    • 0019048796 scopus 로고
    • Purification and properties of mitochondrial and peroxisomal 3-hydroxyacyl-CoA dehydrogenase from rat liver
    • Osumi T, Hashimoto T: Purification and properties of mitochondrial and peroxisomal 3-hydroxyacyl-CoA dehydrogenase from rat liver. Arch Biochem Biophys 203: 372-383, 1980
    • (1980) Arch Biochem Biophys , vol.203 , pp. 372-383
    • Osumi, T.1    Hashimoto, T.2


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