Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cells

Breast Cancer Research

Volumn 9, Issue 4, 2007, Pages

  Sugimoto, Takeshi ^a   Bartholomeusz, Chandra ^a   Tari, Ana M ^a   Ueno, Naoto T ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; CELECOXIB; E1A PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROTEIN BCL 2; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; PTGS2 PROTEIN, HUMAN; PYRAZOLE DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER GENE THERAPY; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; DRUG SENSITIVITY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; OVARY CANCER; WESTERN BLOTTING; BREAST TUMOR; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; FEMALE; GENETIC TRANSFECTION; GENETICS; METABOLISM; OVARY TUMOR; PATHOLOGY;

ADENOVIRUS E1A PROTEINS; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL SURVIVAL; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROST; DINOPROSTONE; FEMALE; FLOW CYTOMETRY; HUMANS; OVARIAN NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRAZOLES; SULFONAMIDES; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 36749053442     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr1739     Document Type: Article

References (50)

1. Xing X Yujiao Chang J Hung M: Preclinical and clinical study of HER-2/ neu-targeting cancer gene therapy. Adv Drug Deliv Rev 1998, 30:219-227. 10.1016/S0169-409X(97)00118-X 10837613
2. Hortobagyi GN Ueno NT Xia W Zhang S Wolf JK Putnam JB Weiden PL Willey JS Carey M Branham DL: Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: A phase I clinical trial. J Clin Oncol 2001, 19:3422-3433. 11454891
3. Villaret D Glisson B Kenady D Hanna E Carey M Gleich L Yoo GH Futran N Hung MC Anklesaria P: A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma. Head Neck 2002, 24:661-669. 10.1002/hed.10107 12112540
4. Frisch SM MyPryk JS: Adenovirus-5 E1A: paradox and paradigm. Nat Rev Mol Cell Biol 2002, 3:441-452. 10.1038/nrm827 12042766
5. Berk AJ: Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene 2005, 24:7673-7685. 10.1038/ sj.onc.1209040 16299528
6. Gomez-Manzano C Yung WK Alemany R Fueyo J: Genetically modified adenoviruses against gliomas: From bench to bedside. Neurology 2004, 63:418-426. 15304571
7. Trimarchi JM Lees JA: Sibling rivalry in the E2F family. Nat Rev Mol Cell Biol 2002, 3:11-20. 10.1038/nrm714 11823794
8. Evan GI Vousden KH: Proliferation, cell cycle and apoptosis in cancer. Nature 2001, 411:342-348. 10.1038/35077213 11357141
9. Wu X Levine AJ: P53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci USA 1994, 91:3602-3606. 43628 8170954 10.1073/pnas.91.9.3602
10. Teodoro JG Shore GC Branton PE: Adenovirus E1A proteins induce apoptosis by both p53-dependent and p53-independent mechanisms. Oncogene 1995, 11:467-474. 7630630
11. Chen MJ Holskin B Strickler J Gorniak J Clark MA Johnson PJ Mitcho M Shalloway D: Induction by E1A oncogene expression of cellular susceptibility to lysis by TNF. Nature 1987, 330:581-583. 10.1038/ 330581a0 2960901
12. Duerksen-Hughes P Wold WS Gooding LR: Adenovirus E1A renders infected cells sensitive to cytolysis by tumor necrosis factor. J Immunol 1989, 143:4193-4200. 2531778
13. Routes JM Ryan S Clase A Miura T Kuhl A Potter TA Cook JL: Adenovirus E1A oncogene expression in tumor cells enhances killing by TNF-related apoptosis-inducing ligand (TRAIL). J Immunol 2000, 165:4522-4527. 11035092
14. Shao R Lee DF Wen Y Ding Y Xia W Ping B Yagita H Spohn B Hung MC: E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation. Mol Cancer Res 2005, 3:219-226. 15831675
15. Liao Y Hung MC: Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis. Mol Cell Biol 2003, 23:6836-6848. 193925 12972603 10.1128/MCB.23.19.6836-6848.2003
16. Shao R Karunagaran D Zhou BP Li K Lo SS Deng J Chiao P Hung MC: Inhibition of nuclear factor-kappaB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis. J Biol Chem 1997, 272:32739-32742. 10.1074/jbc.272.52.32739 9407046
17. Lee WP Liao Y Robinson D Kung HJ Liu ET Hung MC: Axl-gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity. Mol Cell Biol 1999, 19:8075-8082. 84892 10567533
18. Bartholomeusz C Itamochi H Yuan LX Esteva FJ Wood CG Terakawa N Hung MC Ueno NT: Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model. Cancer Res 2005, 65:8406-8413. 10.1158/0008-5472.CAN-05-1754 16166319
19. Liu XH Yao S Kirschenbaum A Levine AC: NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells. Cancer Res 1998, 58:4245-4249. 9766645
20. Subhashini J Mahipal SV Reddanna P: Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro. Cancer Lett 2005, 224:31-43. 15911099
21. Catalano A Graciotti L Rinaldi L Raffaelli G Rodilossi S Betta P Gianni W Amoroso S Procopio A: Preclinical evaluation of the nonsteroidal anti-inflammatory agent celecoxib on malignant mesothelioma chemoprevention. Int J Cancer 2004, 109:322-328. 10.1002/ijc.11710 14961568
22. Li XH Li JJ Zhang HW Sun P Zhang YL Cai SH Ren XD: Nimesulide inhibits tumor growth in mice implanted hepatoma: Overexpression of Bax over Bcl-2. Acta Pharmacol Sin 2003, 24:1045-1050. 14531950
23. Basu GD Pathangey LB Tinder TL Lagioia M Gendler SJ Mukherjee P: Cyclooxygenase-2 inhibitor induces apoptosis in breast cancer cells in an in vivo model of spontaneous metastatic breast cancer. Mol Cancer Res 2004, 2:632-642. 15561779
24. Pereg D Lishner M: Non-steroidal anti-inflammatory drugs for the prevention and treatment of cancer. J Intern Med 2005, 258:115-123. 10.1111/j.1365-2796.2005.01519.x 16018788
25. Tsujii M DuBois RN: Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995, 83:493-501. 10.1016/0092-8674(95)90127-2 8521479
26. Sheng H Shao J Morrow JD Beauchamp RD DuBois RN: Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res 1998, 58:362-366. 9443418
27. Shao R Hu MC Zhou BP Lin SY Chiao PJ von Lindern RH Spohn B Hung MC: E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities. J Biol Chem 1999, 274:21495-21498. 10.1074/jbc.274.31.21495 10419449
28. Meric F Liao Y Lee WP Pollock RE Hung MC: Adenovirus 5 early region 1A does not induce expression of the ewing sarcoma fusion product EWS-FLI1 in breast and ovarian cancer cell lines. Clin Cancer Res 2000, 6:3832-3836. 11051226
29. Kern MA Schubert D Sahi D Schoneweiss MM Moll I Haugg AM Dienes HP Breuhahn K Schirmacher P: Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells. Hepatology 2002, 36:885-894. 12297835
30. Zou Y Peng H Zhou B Wen Y Wang SC Tsai EM Hung MC: Systemic tumor suppression by the proapoptotic gene bik. Cancer Res 2002, 62:8-12. 11782349
31. Tuynman JB Peppelenbosch MP Richel DJ: COX-2 inhibition as a tool to treat and prevent colorectal cancer. Crit Rev Oncol Hematol 2004, 52:81-101. 10.1016/S1040-8428(04)00139-8 15501074
32. Hsu AL Ching TT Wang DS Song X Rangnekar VM Chen CS: The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. J Biol Chem 2000, 275:11397-11403. 10.1074/jbc.275.15.11397 10753955
33. Cao Y Prescott SM: Many actions of cyclooxygenase-2 in cellular dynamics and in cancer. J Cell Physiol 2002, 190:279-286. 10.1002/jcp.10068 11857443
34. Liu CH Chang SH Narko K Trifan OC Wu MT Smith E Haudenschild C Lane TF Hla T: Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem 2001, 276:18563-18569. 10.1074/jbc.M010787200 11278747
35. Jabbour HN Sales KJ Boddy SC Anderson RA Williams AR: A positive feedback loop that regulates cyclooxygenase-2 expression and prostaglandin F2α synthesis via the F-series-prostanoid receptor and extracellular signal-regulated kinase 1/2 signaling pathway. Endocrinology 2005, 146:4657-4664. 10.1210/en.2005-0804 16081631
36. Ding J Tsuboi K Hoshikawa H Goto R Mori N Katsukawa M Hirai E Yamamoto S Abe M Ueda N: Cyclooxygenase isozymes are expressed in human myeloma cells but not involved in anti-proliferative effect of cyclooxygenase inhibitors. Mol Carcino 2006, 45:250-259. 10.1002/mc.20175
37. Jerde TJ Calamon-Dixon JL Bjorling DE Nakada SY: Celecoxib inhibits ureteral contractility and prostanoid release. Urology 2005, 65:185-190. 10.1016/j.urology.2004.08.057 15667901
38. Nithipatikom K Isbell MA Lindholm PF Kajdacsy-Balla A Kaul S Campell WB: Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. Clin Exp Metastasis 2002, 19:593-601. 10.1023/A:1020915914376 12498388
39. Davis JN McCabe MT Hayward SW Park JM Day ML: Disruption of Rb/E2F pathway results in increased cyclooxygenase-2 expression and activity in prostate epithelial cells. Cancer Res 2005, 65:3633-3642. 10.1158/ 0008-5472.CAN-04-3129 15867358
40. Nevins JR: The Rb/E2F pathway and cancer. Hum Mol Genet 2001, 10:699-703. 10.1093/hmg/10.7.699 11257102
41. Tsantoulis PK Gorgoulis VG: Involvement of E2F transcription factor family in cancer. Eur J Cancer 2005, 41:2403-2414. 10.1016/ j.ejca.2005.08.005 16213134
42. Dandekar DS Lopez M Carey RI Lokeshwar BL: Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells. Int J Cancer 2005, 115:484-492. 10.1002/ijc.20878 15688368
43. Zhang Z Lai GH Sirica AE: Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation. Hepatology 2004, 39:1028-1037. 10.1002/hep.20143 15057907
44. Narayanan BA Condon MS Bosland MC Narayanan NK Reddy BS: Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: Effects on cyclooxygenase-2, cell cycle regulation, and apoptosis mechanism(s). Clin Cancer Res 2003, 9:3503-3513. 12960143
45. Yao M Kargman S Lam EC Kelly CR Zheng Y Luk P Kwong E Evans JF Wolfe MM: Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice. Cancer Res 2003, 63:586-592. 12566300
46. Basu GD Pathangey LB Tinder TL Gendler SJ Mukherjee P: Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells. Breast Cancer Res 2005, 7:422-435. 10.1186/bcr1019
47. Liu XH Rose DP: Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines. Cancer Res 1996, 56:5125-5127. 8912844
48. Timoshenko AV Xu G Chakrabarti S Lala PK Chakraborty C: Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells. Exp Cell Res 2003, 289-265. 274 10.1016/ S0014-4827(03)00269-6 14499627
49. Agarwal B Swaroop P Protiva P Raj SV Shirin H Holt PR: Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells. Apoptosis 2003, 8:649-654. 10.1023/ A:1026199929747 14739610
50. Kong G Kim HT Wu K DeNardo D Hilsenbeck SG Xu XC Lamph WW Bissonnette R Dannenberg AJ Brown PH: The retinoid X receptor-selective retinoid, LGD down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: Implications for molecular-based chemoprevention. Cancer Res 1069, 65:3462-3469.