Site-directed disulfide cross-linking shows that cleft flexibility in the periplasmic domain is needed for the multidrug efflux pump AcrB of Escherichia coli

Journal of Bacteriology

Volumn 189, Issue 23, 2007, Pages 8677-8684

  Takatsuka, Yumiko ^a   Nikaido, Hiroshi ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CYSTEINE; DISULFIDE; DSBA PROTEIN; GLYCOPROTEIN P; PROTEIN ARCB; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; CYTOPLASM; DISULFIDE BOND; ESCHERICHIA COLI; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS;

DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; MODELS, MOLECULAR; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEIN DISULFIDE-ISOMERASE; PROTEIN STRUCTURE, TERTIARY;

ESCHERICHIA COLI;

EID: 36749045119     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01127-07     Document Type: Article

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