Mannose-binding lectin and the kidney

Nephrology Dialysis Transplantation

Volumn 22, Issue 12, 2007, Pages 3370-3377

  Roos, Anja ^a   Daha, Mohamed R ^a   Van Pelt, Johannes ^a   Berger, Stefan P ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Complement; Diabetes; Ficolin; IgA nephropathy; Ischaemia reperfusion injury; Lectin pathway; Mannose binding lectin; Transplantation

Indexed keywords

COMPLEMENT COMPONENT C1; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C4B; COMPLEMENT COMPONENT C5B; FICOLIN; IMMUNOSUPPRESSIVE AGENT; INSULIN; MANNOSE BINDING LECTIN;

ACUTE GRAFT REJECTION; ADAPTIVE IMMUNITY; ANTIGEN ANTIBODY COMPLEX; ANTIGEN PRESENTATION; CARDIOVASCULAR RISK; COMPLEMENT SYSTEM; DIABETIC NEPHROPATHY; DIABETIC PATIENT; HIGH RISK PATIENT; HUMAN; HUMORAL IMMUNITY; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOSUPPRESSIVE TREATMENT; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; KIDNEY FUNCTION; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; REVIEW;

ANIMALS; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; HUMANS; KIDNEY; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; MANNOSE-BINDING LECTIN;

EID: 36749021227     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfm524     Document Type: Review

References (66)

1. Walport MJ. Complement. Second of two parts. N Engl J.Med 2001; 344: 1140-1144
2. Walport MJ. Complement. First of two parts. N Engl J Med 2001; 344: 1058-1066
3. Selander B, Martensson U, Weintraub A et al. Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2. J Clin Invest 2006; 116: 1425-1434
4. Daha MR, Van Kooten C, Roos A. Compliments from complement: a fourth pathway of complement activation? Nephrol Dial Transplant 2006; 21: 3374-3376
5. Petersen SV, Thiel S, Jensenius JC. The mannan-binding lectin pathway of complement activation: biology and disease association. Mol Immunol 2001; 38: 133-149
6. Holmskov U, Thiel S, Jensenius JC. Collectins and ficolins: humoral lectins of the innate immune defense. Annu Rev Immunol 2003; 21: 547-578
7. Matsushita M, Endo Y, Fujita T. Complement-activating complex of ficolin and mannose-binding lectin-associated serine protease. J Immunol 2000; 164: 2281-2284
8. Matsushita M, Kuraya M, Hamasaki N et al. Activation of the lectin complement pathway by H-ficolin (Hakata antigen). J Immunol 2002; 168: 3502-3506
9. Liu Y, Endo Y, Iwaki D et al. Human M-ficolin is a secretory protein that activates the lectin complement pathway. J Immunol 2005; 175: 3150-3156
10. Dommett RM, Klein N, Turner MW. Mannose-binding lectin in innate immunity: past, present and future. Tissue Antigens 2006; 68: 193-209
11. Sumiya M, Super M, Tabona P et al. Molecular basis of opsonic defect in immunodeficient children. Lancet 1991; 337: 1569-1570
12. Lipscombe RJ, Sumiya M, Hill AV et al. High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene. Hum Mol Genet 1992; 1: 709-715
13. Madsen HO, Garred P, Kurtzhals JAL et al. A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein. Immunogenetics 1994; 40: 37-44
14. Roos A, Garred P, Wildenberg ME et al. Antibody-mediated activation of the classical pathway of complement may compensate for mannose-binding lectin deficiency. Eur J Immunol 2004; 34: 2589-2598
15. Larsen F, Madsen HO, Sim RB, Koch C, Garred P. Disease-associated mutations in human mannose-binding lectin compromise oligomerisation and activity of the final protein. J Biol Chem 2004; 279: 21302-21311
16. Madsen HO, Garred P, Thiel S et al. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 1995; 155: 3013-3020
17. Madsen HO, Satz ML, Hogh B, Svejgaard A, Garred P. Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America. J Immunol 1998; 161: 3169-3175
18. Saevarsdottir S, Oskarsson OO, Aspelund T et al. Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk. J Exp Med 2005; 201: 117-125
19. Petersen SV, Thiel S, Jensen L, Steffensen R, Jensenius JC. An assay for the mannan-binding lectin pathway of complement activation. J Immunol Methods 2001; 257: 107-116
20. Roos A, Bouwman LH, Munoz J et al. Functional characterization of the lectin pathway of complement in human serum. Mol Immunol 2003; 39: 655-668
21. Garred P, Harboe M, Oettinger T, Koch C, Svejgaard A. Dual role of mannan-binding protein in infections: another case of heterosis? Eur J Immunogenet 1994; 21: 125-131
22. Peterslund NA, Koch C, Jensenius JC, Thiel S. Association between deficiency of mannose-binding lectin and severe infections after chemotherapy. Lancet 2001; 358: 637-638
23. Bouwman LH, Roos A, Terpstra OT et al. Mannose binding lectin gene polymorphisms confer a major risk for severe infections after liver transplantation. Gastroenterology 2005; 129: 408-414
24. Wyatt RJ, Kanayama Y, Julian BA et al. Complement activation in IgA nephropathy. Kidney Int 1987; 31: 1019-1023
25. Miyazaki R, Kuroda M, Akiyama T et al. Glomerular deposition and serum levels of complement control proteins in patients with IgA nephropathy. Clin Nephrol 1984; 21: 335-340
26. Matsuda M, Shikata K, Wada J et al. Deposition of mannan binding protein and mannan binding protein-mediated complement activation in the glomeruli of patients with IgA nephropathy. Nephron 1998; 80: 408-413
27. Lhotta K, Würzner R, König P. Glomerular deposition of mannose-binding lectin in human glomerulonephritis. Nephrol Dial Transplant 1999; 14: 881-886
28. Endo M, Ohi H, Ohsawa I et al. Glomerular deposition of mannose-binding lectin (MBL) indicates a novel mechanism of complement activation in IgA nephropathy. Nephrol Dial Transplant 1998; 13: 1984-1990
29. Endo M, Ohi H, Ohsawa I et al. Complement activation through the lectin pathway in patients with Henoch-Schönlein purpura nephritis. Am J Kidney Dis 2000; 35: 401-407
30. Hisano S, Matsushita M, Fujita T, Iwasaki H. Activation of the lectin complement pathway in Henoch-Schonlein purpura nephritis. Am J Kidney Dis 2005; 45: 295-302
31. Roos A, Bouwman LH, van Gijlswijk-Janssen DJ et al. Human IgA activates the complement system via the mannan-binding lectin pathway. J Immunol 2001; 167: 2861-2868
32. Roos A, Rastaldi MP, Calvaresi N et al. Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol 2006; 17: 1724-1734
33. Hansen TK, Thiel S, Knudsen ST et al. Elevated levels of mannan-binding lectin in patients with type 1 diabetes. J Clin Endocrinol Metab 2003; 88: 4857-4861
34. Hansen TK, Tarnow L, Thiel S et al. Association between mannose-binding lectin and vascular complications in type 1 diabetes. Diabetes 2004; 53: 1570-1576
35. Bouwman LH, Eerligh P, Terpstra OT et al. Elevated levels of mannose-binding lectin at clinical manifestation of type 1 diabetes in juveniles. Diabetes 2005; 54: 3002-3006
36. Hansen TK, Thiel S, Wouters PJ, Christiansen JS, Van den BG. Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J Clin Endocrinol Metab 2003; 88: 1082-1088
37. Saraheimo M, Forsblom C, Hansen TK et al. Increased levels of mannan-binding lectin in type 1 diabetic patients with incipient and overt nephropathy. Diabetologia 2005; 48: 198-202
38. Hansen TK, Gall MA, Tarnow L et al. Mannose-binding lectin and mortality in type 2 diabetes. Arch Intern Med 2006; 166: 2007-2013
39. Hovind P, Hansen TK, Tarnow L et al. Mannose-binding lectin as a predictor of microalbuminuria in type 1 diabetes: an inception cohort study. Diabetes 2005; 54: 1523-1527
40. Ostergaard J, Thiel S, Gadjeva M et al. Mannose-binding lectin deficiency attenuates renal changes in a streptozotocin-induced model of type 1 diabetes in mice. Diabetologia 2007; 50: 1541-1549
41. Riedemann NC, Ward PA. Complement in ischemia reperfusion injury. Am J Pathol 2003; 162: 363-367
42. Zhou W, Farrar CA, Abe K et al. Predominant role for C5b-9 in renal ischemia/reperfusion injury. J Clin Invest 2000; 105: 1363-1371
43. Bonventre JV. Complement and renal ischemia-reperfusion injury. Am J Kidney Dis 2001; 38: 430-436
44. de Vries B, Köhl J, Leclercq WKG et al. Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils. J Immunol 2003; 170: 3883-3889
45. de Vries B, Matthijsen RA, Wolfs TGAM et al. Inhibition of complement factor C5 protects against renal ischemia-reperfusion injury: inhibition of late apoptosis and inflammation. Transplantation 2003; 75: 375-382
46. Collard CD, Lekowski R, Jordan JE, Agah A, Stahl GL. Complement activation following oxidative stress. Mol Immunol 2002; 36: 941-948
47. Collard CD, Väkevä A, Morrissey MA et al. Complement activation after oxidative stress: role of the lectin complement pathway. Am J Pathol 2000; 156: 1549-1556
48. Jordan JE, Montalto MC, Stahl GL. Inhibition of mannose-binding lectin reduces postischemic myocardial reperfusion injury. Circulation 2001; 104: 1413-1418
49. Walsh MC, Bourcier T, Takahashi K et al. Mannose-binding lectin is a regulator of inflammation that accompanies myocardial ischemia and reperfusion injury. J Immunol 2005; 175: 541-546
50. Hart ML, Ceonzo KA, Shaffer LA et al. Gastrointestinal ischemia-reperfusion injury is lectin complement pathway dependent without involving C1q. J Immunol 2005; 174: 6373-6380
51. de Vries B, Walter SJ, Peutz-Kootstra CJ et al. The mannose-binding lectin-pathway is involved in complement activation in the course of renal ischemia-reperfusion injury. Am J Pathol 2004; 165: 1677-1688
52. Moller-Kristensen M, Wang W, Ruseva M et al. Mannan-binding lectin recognizes structures on ischaemic reperfused mouse kidneys and is implicated in tissue injury. Scand J Immunol 2005; 61: 426-434
53. Zhang M, Takahashi K, Alicot EM et al. Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury. J Immunol 2006; 177: 4727-4734
54. Pratt JR, Hibbs MJ, Laver AJ, Smith RA, Sacks SH. Allograft immune response with sCR1 intervention. Transpl Immunol 1996; 4: 72-75
55. Pratt JR, Hibbs MJ, Laver AJ, Smith RA, Sacks SH. Effects of complement inhibition with soluble complement receptor-1 on vascular injury and inflammation during renal allograft rejection in the rat. Am J Pathol 1996; 149: 2055-2066
56. Pratt JR, Basheer SA, Sacks SH. Local synthesis of complement component C3 regulates acute renal transplant rejection. Nat Med 2002; 8: 582-587
57. Brown KM, Kondeatis E, Vaughan RW et al. Influence of donor C3 allotype on late renal-transplantation outcome. N Engl J Med 2006; 354: 2014-2023
58. Lin T, Zhou W, Farrar CA et al. Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection. Am J Pathol 2006; 168: 1241-1248
59. Berger SP, Roos A, Mallat MJ et al. Association between mannose-binding lectin levels and graft survival in kidney transplantation. Am J Transplant 2005; 5: 1361-1366
60. Berger SP, Roos A, Mallat MJ, Daha MR, de Fijter JW. Pre-transplantation MBL levels predict patient and graft survival after simultaneous pancreas-kidney transplantation. J Am Soc Nephrol 2007; 18: 2416-2422
61. Sund S, Hovig T, Reisaeter AV et al. Complement activation in early protocol kidney graft biopsies after living-donor transplantation. Transplantation 2003; 75: 1204-1213
62. Imai N, Nishi S, Alchi B et al. Immunohistochemical evidence of activated lectin pathway in kidney allografts with peritubular capillary C4d deposition. Nephrol Dial Transplant 2006; 21: 2589-2595
63. Farrar CA, Zhou W, Lin T, Sacks SH. Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J 2006; 20: 217-226
64. Quigg RJ. Complement and the kidney. J Immunol 2003; 171: 3319-3324
65. Ohsawa I, Ohi H, Endo M et al. Evidence of lectin complement pathway activation in poststreptococcal glomerulonephritis. Kidney Int 1999; 56: 1158-1159
66. Seyfarth J, Garred P, Madsen HO. Extra-hepatic transcription of the human mannose-binding lectin gene (mbl2) and the MBL-associated serine protease 1-3 genes. Mo Immunol 2006; 43: 962-971