Cutting edge: Complement-activating complex of ficolin and mannose- binding lectin-associated serine protease

Journal of Immunology

Volumn 164, Issue 5, 2000, Pages 2281-2284

  Matsushita, Misao ^a   Endo, Yuichi ^a   Fujita, Teizo ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE BINDING PROTEIN; COLLAGEN; COMPLEMENT; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; FIBRINOGEN; LECTIN; MANNOSE BINDING PROTEIN; PROTEIN P35; SERINE PROTEINASE;

ARTICLE; COMPLEMENT ACTIVATION; HUMAN; IMMUNITY; LECTIN BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN;

EID: 0034163330     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2281     Document Type: Article

References (29)

1. Lu, J., and Y. Le. 1998. Ficolins and the fibrinogen-like domain. Immunobiology 199:190.
2. Turner, M. W. 1996. Mannose-binding lectin: the pluripotent molecule of the innate immune system. Immunol. Today 17:532.
3. Ichijo, H., L. Ronnstrand, K. Miyagawa, H. Ohashi, C. H. Heldin, and K. Miyazono. 1991. Purification of transforming growth factor-β 1 binding proteins from porcine uterus membranes. J. Biol. Chem. 266:22459.
4. Ichijo, H., U. Hellman, C. Wernstedt, L. J. Gonez, L. Claesson-Welsh, C. H. Helden, and K. Miyazono. 1993. Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains. J. Biol. Chem. 268:14505.
5. Endo, Y., Y. Sato, M. Matsushita, and T. Fujita. 1996. Cloning and characterization of the human lectin P35 gene and its related gene. Genomics 36:515.
6. Lu, J., P. N. Tay, O. L. Kon, and K. B. M. Reid. 1996. Human ficolin: cDNA cloning, demonstration of peripheral blood leucocytes as the major site of synthesis and assignment of the gene to chromosome 9. Biochem. J. 313:473.
7. Harumiya, S., A. Omori, T. Sugiura, Y. Fukumoto, H. Tachikawa, and D. Fujimoto. 1995. EBP-37, a new elastin-binding protein in human plasma: structural similarity to ficolins, tranforming growth factor-β1-binding proteins. J. Biochem. 117:1029.
8. Edgar, P. F. 1995. Hucolin, a new corticosteroid-binding protein from human plasma with structural similarities to ficolins, transforming growth factor-β1-binding proteins. FEBS Lett. 375:159.
9. Lu, J., Y. Le, L. Kon, J. Chan, and S. H. Lee. 1996. Biosynthesis of human ficolin, an Escherichia coli-binding protein, by monocytes: comparison with the synthesis of two macrophage-specific proteins, Clq and the mannose receptor. Immunology 89:289.
10. Matsushita, M., Y. Endo, S. Taira, Y. Sato, T. Fujita, N. Ichikawa, M. Nakata, and T. Mizuochi. 1996. A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin. J. Biol. Chem. 271:2448.
11. Le, Y., S. H. Lee, O. L. Kon, and J. Lu. 1998. Human L-ficolin: plasma levels, sugar specificity, and assignment of its lectin activity to the fibrinogen-like (FBG) domain. FEBS Lett. 425:367.
12. Sugimoto, R., Y. Yae., M. Akaiwa, S. Kitajima, Y. Shibata, H. Sato, J. Hirata, K. Okochi, K. Izuhara, and N. Hamasaki. 1998. Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family. J. Biol. Chem. 273:20721.
13. Matsushita, M., Y. Endo, M. Nonaka, and T. Fujita. 1998. Complement-related serine proteases in tunicates and vertebrates. Curr. Opin. Immunol. 10:29.
14. Matsushita, M., and T. Fujita. 1992. Activation of the classical complement pathway by mannose-binding protein in association with a novel Cls-like serine protease. J. Exp. Med. 176:1497.
15. Sato, T., Y. Endo, M. Matsushita, and T. Fujita. 1994. Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein. Int. Immunol. 6:665.
16. Takada, F., H. Takayama, H. Hatsuse, and M. Kawakami. 1994. A new member of the Cls family of component protein found in a bactericidal factor, Ra-reactive factor, in human serum. Biochem. Biophys. Res. Commun. 196:1003.
17. Thiel, S., T. Vorup-Jensen, C. M. Stover, W. Schwaeble, S. B. Laursen, K. Poulsen, A. C. Willis, P. Eggleton, S. Hansen, U. Holmskov, K. B. M. Reid, and J. C. Jensenius. 1997. A second serine protease associated with mannan-binding lectin that activates complement. Nature 386:506.
18. Matsushita, M., and T. Fujita. 1995. Cleavage of the third component of complement (C3) by mannose-binding protein-associated serine protease (MASP) with subsequent complement activation. Immunobiology 194:443.
19. Takahashi, M., Y. Endo, T. Fujila, and M. Matsushita. 1999. A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway. Int. Immunol. 11:859.
20. Stover, C. D., S. Thiel, M. Thelen, N. J. Lynch, T. Vorup-Jensen, J. C. Jensenius, and W. J. Schwaeble. 1999. Two constituents of the initiation complex of the mannan-binding lectin activation pathway of the complement are encoded by a single structural gene. J. Immunol. 162:3481.
21. Hoffmann, J. A., F. C. Kafatos, C. A. Janeway, Jr., and R. A. B. Ezekowitz. 1999. Phylogenetic perspectives in innate immunity. Science 284:1313.
22. Kilpatrick, D. C., T. Fujita, and M. Matsushita. 1999. P35, an opsonic lectin of the ficolin family, in human blood from neonates, normal adults, and recurrent miscarriage patients. Immunol. Lett. 67:109.
23. Matsushita, M., and H. Okada. 1996. Alternative complement pathway activation by C4b deposited during classical complement pathway activation. J. Immunol. 146:2994.
24. Ohta, M., M. Okada, I. Yamashina, and T. Kawasaki. 1990. The mechanism of carbohydrate-mediated complement activation by the serum mannan-binding protein. J. Biol. Chem. 265:1980.
25. Lu, J., S. Thiel, H. Wiedemann, R. Timpl, and K.B.M. Reid. 1990. Binding of the pentamer/hexamer forms of mannan-binding protein to zymosan activates the proenzyme ClrCls complex, of the classical pathway of complement, without involvement of Clq. J. Immunol. 144:2287.
26. Matsushita, M., R. A. B. Ezekowitz, and T. Fujita. 1995. The Gly-54-→Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease. Biochem. J. 311:1021.
27. Chiquest-Ehrismann, R., E. J. Mackie, S. A. Latt, and J. Floros. 1986. An extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis. Cell 47:131.
28. Baker, N. E., M. Mlodzik, and G. M. Rubin, 1990. Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous. Science 250:1370.
29. Gokudan, S., T. Muta, R. Tsuda, K. Koori, T. Kawahara, N. Seki, Y. Mizunoe, S. N. Wai, S. Iwanaga, and S.-I. Kawabata. 1999. Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen. Proc. Natl. Acad. Sci. USA 96:10086.