Human M-ficolin is a secretory protein that activates the lectin complement pathway

Journal of Immunology

Volumn 175, Issue 5, 2005, Pages 3150-3156

  Liu, Yu ^a   Endo, Yuichi ^a,b   Iwaki, Daisuke ^a,b   Nakata, Munehiro ^c   Matsushita, Misao ^c   Wada, Ikuo ^a   Inoue, Keiichi ^a   Munakata, Mitsuru ^a   Fujita, Teizo ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; FICOLIN; H FICOLIN; L FICOLIN; LECTIN; M FICOLIN; MANNOSE BINDING LECTIN; MASP 1; MASP 2; N ACETYLGLUCOSAMINE; NEOGLYCOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INNATE IMMUNITY; LEUKOCYTE; LUNG ALVEOLUS EPITHELIUM; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STAPHYLOCOCCUS AUREUS;

EID: 23844486704     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.5.3150     Document Type: Article

References (40)

1. Matsushita, M., and T. Fujita. 2001. Ficolins and the lectin complement pathway. Immunol. Rev. 180: 78-85.
2. Matsushita, M., and T. Fujita. 2002. The role of ficolins in innate immunity. Immunobiology 205: 490-497.
3. Fujita, T. 2002. Evolution of the lectin-complement pathway and its role in innate immunity. Nat. Rev. Immunol. 2: 346-353.
4. Ichijo, H., U. Hellman, C. Wernstedt, L. J. Gonez, L. Claesson-Welsh, C. H. Heldin, and K. Miyazono. 1993. Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains. J. Biol. Chem. 268: 14505-14513.
5. Endo, Y., Y. Sato, M. Matsushita, and T. Fujita. 1996. Cloning and characterization of the human lectin P35 gene and its related gene. Genomics 36: 515-521.
6. Lu, J., P. N. Tay, O. L. Kon, and K. B. Reid. 1996. Human ficolin: cDNA cloning, demonstration of peripheral blood leucocytes as the major site of synthesis and assignment of the gene to chromosome 9. Biochem. J. 313(Pt. 2): 473-478.
7. Sugimoto, R., Y. Yae, M. Akaiwa, S. Kitajima, Y. Shibata, H. Sato, J. Hirata, K. Okochi, K. Izuhara, and N. Hamasaki. 1998. Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family. J. Biol. Chem. 273: 20721-20727.
8. Matsushita, M., Y. Endo, S. Taira, Y. Sato, T. Fujiia, N. Ichikawa, M. Nakata, and T. Mizuochi. 1996. A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin. J. Biol. Chem. 271: 2448-2454.
9. Fujimori, Y., S. Harumiya, Y. Fukumoto, Y. Miura, K. Yagasaki, H. Tachikawa, and D. Fujimoto. 1998. Molecular cloning and characterization of mouse ficolin-A. Biochem. Biophys. Res. Commun. 244: 796-800.
10. Ohashi, T., and H. P. Erickson. 1998. Oligomeric structure and tissue distribution of ficolins from mouse, pig and human. Arch. Biochem. Biophys. 360: 223-232.
11. Omori-Satoh, T., Y. Yamakawa, and D. Mebs. 2000. The antihemorrhagic factor, erinacin, from the European hedgehog (Erinaceus europaeus), a metalloprotease inhibitor of large molecular size possessing ficolin/opsonin P35 lectin domains. Toucan 38: 1561-1580.
12. Kakinuma, Y., Y. Endo, M. Takahashi, M. Nakata, M. Matsushita, S. Takenoshita, and T. Fujita. 2003. Molecular cloning and characterization of novel ficolins from Xenopus iaevis. Immunogenetics 55: 29-37.
13. Kenjo, A., M. Takahashi, M. Matsushita, Y. Endo, M. Nakata, T. Mizuochi, and T. Fujita. 2001. Cloning and characterization of novel ficolins from the solitary ascidian, Halocynthia roretzi. J. Biol. Chem. 276: 19959-19965.
14. Teh, C., Y. Le, S. H. Lee, and J. Lu. 2000. M-ficolin is expressed on monocytes and is a lectin binding to N-acetyl-D-glucosamine and mediates monocyte adhesion and phagocytosis of Escherichia coli. Immunology 101: 225-232.
15. Matsushita, M., R. A. Ezekowitz, and T. Fujita. 1995. The Gly-54→Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease. Biochem. J. 311(Pt 3): 1021-1023.
16. Matsushita, M., Y. Endo, N. Hamasaki, and T. Fujita. 2001. Activation of the lectin complement pathway by ficolins. Int. Immunopharmacol. 1: 359-363.
17. Aoyagi, Y., E. E. Adderson, J. G. Min, M. Matsushita, T. Fujita, S. Takahashi, Y. Okuwaki, and J. F. Bohnsack. 2005. Role of L-ficolin/mannose- binding lectin-associated serine protease complexes in the opsonophagocytosis of type III group B streptococci. J. Immunol. 174: 418-425.
18. Krarup, A., S. Thiel, A. Hansen, T. Fujita, and J. C. Jensenius. 2004. L-ficolin is a pattern recognition molecule specific for acetyl groups. J. Biol. Chem. 279: 47513-47519.
19. Matsushita, M., M. Kuraya, N. Hamasaki, M. Tsujimura, H. Shiraki, and T. Fujita. 2002. Activation of the lectin complement pathway by H-ficolin (Hakata antigen). J. Immunol. 168: 3502-3506.
20. Tsujimura, M., T. Miyazaki, E. Kojima, Y. Sagara, H. Shiraki, K. Okochi, and Y. Maeda. 2002. Serum concentration of Hakata antigen, a member of the ficolins, is linked with inhibition of Aerococcus viridans growth. Clin. Chim. Acta 325: 139-146.
21. Harumiya, S., K. Takeda, T. Sugiura, Y. Fukumoto, H. Tachikawa, K. Miyazono, D. Fujimoto, and H. Ichijo. 1996. Characterization of ficolins as novel elastin-binding proteins and molecular cloning of human ficolin-1. J. Biochem. 120: 745-751.
22. Lu, J., Y. Le, O. L. Kon, J. Chan, and S. H. Lee. 1996. Biosynthesis of human ficolin, an Escherichia coli-binding protein, by monocytes: comparison with the synthesis of two macrophage-specific proteins, Clq and the mannose receptor. Immunology 89: 289-294.
23. Hashimoto, S., T. Suzuki, H. Y. Dong, S. Nagai, N. Yamazaki, and K. Matsushima. 1999. Serial analysis of gene expression in human monocyte-derived dendritic cells. Blood 94: 845-852.
24. Hashimoto, S., T. Suzuki, H. Y. Dong, N. Yamazaki, and K. Matsushima. 1999. Serial analysis of gene expression in human monocytes and macrophages. Blood 94: 837-844.
25. Matsushita, M., S. Thiel, J. C. Jensenius, I. Terai, and T. Fujita. 2000. Proteolytic activities of two types of mannose-binding lectin-associated serine protease. J. Immunol. 165: 2637-2642.
26. Mizuochi, T., R. W. Loveless, A. M. Lawson, W. Chai, P. J. Lachmann, R. A. Childs, S. Thiel, and T. Feizi. 1989. A library of oligosaccharide probes (neoglycolipids) from N-glycosylated proteins reveals that conglutinin binds to certain complex-type as well as high mannose-type oligosaccharide chains. J. Biol. Chem. 264: 13834-13839.
27. Loveless, R. W., T. Feizi, R. A. Childs, T. Mizuochi, M. S. Stall, R. G. Oldroyd, and P. J. Lachmann. 1989. Bovine serum conglutinin is a lectin which binds non-reducing terminal N-acetylglucosamine, mannose and fucose residues. Biochem. J. 258: 109-113.
28. Matsushita, M., Y. Endo, and T. Fujita. 2000, Cutting edge: complement-activating complex of ficolin and mannose-binding lectin-associated serine protease. J. Immunol. 164: 2281-2284.
29. Holmskov, U., S. Thiel, and J. C. Jensenius. 2003. Collections and ficolins: humoral lectins of the innate immune defense. Annu. Rev. Immunol. 21: 547-578.
30. Epstein, J., Q. Eichbaum, S. Sheriff, and R. A. Ezekowitz. 1996. The collectins in innate immunity. Can. Opin. Immunol. 8: 29-35.
31. van de Wetering, J. K., L. M. van Golde, and J. J. Batenburg. 2004. Collectins: players of the innate immune system. Eur. J. Biochem. 271: 1229-1249.
32. Sotiropoulou, G., M. Kono, A. Anisowicz, G. Stenman, S. Tsuji, and R. Sager. 2002. Identification and functional characterization of a human GalNAc [α]2,6-sialyltransferase with altered expression in breast cancer. Mol. Med. 8: 42-55.
33. Shi, L., K. Takahashi, J. Dundee, S. Shahroor-Karni, S. Thiel, J. C. Jensenius, F. Gad, M. R. Hamblin, K. N. Sastry, and R. A. Ezekowitz. 2004. Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. J. Exp. Med. 199: 1379-1390.
34. Krarup, A., U. B. Sorensen, M. Matsushita, J. C. Jensenius, and S. Thiel. 2005. Effect of capsulation of opportunistic pathogenic bacteria on binding of the pattern recognition molecules mannan-binding lectin, L-ficolin, and H-ficolin. Infect. Immun. 73: 1052-1060.
35. Akaiwa, M., Y. Yae, R. Sugimoto, S. O. Suzuki, T. Iwaki, K. Izuhara, and N. Hamasaki. 1999. Hakata antigen, a new member of the ficolin/opsonin p35 family, is a novel human lectin secreted into bronchus/alveolus and bile. J. Histochem. Cytochem. 47: 777-786.
36. Kuroki, Y., and D. R. Voelker. 1994. Pulmonary surfactant proteins. J. Biol. Chem. 269: 25943-25946.
37. Wright, J. R. 2005. Immunoregulatory functions of surfactant proteins. Nat. Rev. Immunol. 5: 58-68.
38. Hussain, S. 2004. Role of surfactant protein A in the innate host defense and autoimmunity. Autoimmunity 37: 125-130.
39. Haagsman, H. P., V. Herias, and M. van Eijk. 2003. Surfactant phospholipids and proteins in lung defence. Acta Pharmacol. Sin. 24: 1301-1303.
40. Watford, W. T., J. R. Wright, C. G. Hester, H. Jiang, and M. M. Frank. 2001. Surfactant protein A regulates complement activation. J. Immunol. 167: 6593-6600.