Glial cell line-derived neurotrophic factor and antioxidants preserve the electrical responsiveness of the spiral ganglion neurons after experimentally induced deafness

Neurobiology of Disease

Volumn 29, Issue 1, 2008, Pages 14-21

  Maruyama, Jun ^a,b   Miller, Josef M ^a,c   Ulfendahl, Mats ^a,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Antioxidants; Auditory brainstem response; Cochlea; Deafferentation; Electrical; GDNF; Inner ear; Intervention; Neurotrophic factor; Spiral ganglion

Indexed keywords

ASCORBIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; TROLOX C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY SYSTEM; CELL DEATH; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; ELECTRIC ACTIVITY; ELECTROPHYSIOLOGY; GUINEA PIG; HEARING IMPAIRMENT; HISTOLOGY; MONOTHERAPY; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL;

ACOUSTIC STIMULATION; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; AUDITORY THRESHOLD; CHROMANS; DEAFNESS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG ADMINISTRATION ROUTES; ELECTRIC STIMULATION; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GUINEA PIGS; NEURONS; SPIRAL GANGLION; STATISTICS, NONPARAMETRIC;

EID: 36549067298     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2007.07.026     Document Type: Article

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