GRO-α: A potential marker for cancer and aging silenced by RNA interference

Annals of the New York Academy of Sciences

Volumn 1119, Issue 1, 2007, Pages 176-189

  Fimmel, Sabine ^a   Devermann, Lena ^a   Herrmann, Anke ^a   Zouboulis, Christos ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b DESSAU MEDICAL CENTER   (Germany)

Author keywords

Aging; Cancer; GRO alpha; Melanoma cells; RNA interference; Sebocytes

Indexed keywords

ANGIOGENIC PROTEIN; BIOLOGICAL MARKER; CXCL1 CHEMOKINE; GROWTH REGULATED PROTEIN ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; UNCLASSIFIED DRUG; VASCULOTROPIN;

AGING; CANCER; CANCER CELL; CELL LINE; CELL TYPE; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE EXPRESSION; HORMONE RELEASE; HUMAN; HUMAN CELL; MELANOMA CELL; RNA INTERFERENCE; SEBACEOUS GLAND; TUMOR;

EID: 36549032833     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1404.016     Document Type: Conference Paper

References (50)

1. HILL, A.A. et al. 2000. Genomic analysis of gene expression in C. elegans. Science 290: 809-812.
2. ZOU, S. et al. 2000. Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 97: 13726-13731.
3. LUND, J. et al. 2002. Transcriptional profile of aging in C. elegans. Curr. Biol. 12: 1566-1573.
4. PLETCHER, S.D. et al. 2002. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Curr. Biol. 12: 712-723.
5. MURPHY, C.T. et al. 2003. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283.
6. LEE, C.K. et al. 1999. Gene expression profile of aging and its retardation by caloric restriction. Science 285: 1390-1393.
7. LEE, C.K., R. WEINDRUCH & T.A. PROLLA. 2000. Gene-expression profile of the ageing brain in mice. Nat. Genet. 25: 294-297.
8. SU, A.I. et al. 2002. Large-scale analysis of the human and mouse transcriptomes. Proc. Natl. Acad. Sci. USA 99: 4465-4470.
9. YOSHIDA, S. et al. 2002. Microarray analysis of gene expression in the aging human retina. Invest. Ophthalmol Vis. Sci. 43: 2554-2560.
10. WELLE, S. et al. 2003. Gene expression profile of aging in human muscle. Physiol. Genomics 14: 149-159.
11. WELLE, S. et al. 2004. Skeletal muscle gene expression profiles in 20-29 year old and 65-71 year old women. Exp. Gerontol. 39: 369-377.
12. RODWELL, G.E. et al. 2004. A transcriptional profile of aging in the human kidney. PLoS Biol. 2: e427.
13. HEKIMI, S. & L. GUARENTE. 2003. Genetics and the specificity of the aging process. Science 299: 1351-1354.
14. ADJAYE, J. et al. 2004. Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays. BMC Genomics 5: 83-95.
15. MAKRANTONAKI, E. et al. 2006. Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro. Aging Cell 5: 331-344.
16. RICHMOND, A. et al. 1983. Extraction of a melanoma growth-stimulatory activity from culture medium conditioned by the Hs294T human melanoma cell line. Cancer Res. 43: 2106-2112.
17. RICHMOND, A. et al. 1985. Characterization of autostimulatory and transforming growth factors from human melanoma cells. Cancer Res. 45: 6390-6394.
18. YANG, J. & A. RICHMOND. 2001. Constitutive IκB Kinase Activity Correlates with Nuclear Factor-κB Activation in Human Melanoma Cells. Cancer Res. 61: 4901-4909.
19. CZAUDERNA, F. et al. 2003. Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res. 31: 2705-2716.
20. ZOUBOULIS, Ch.C. et al. 1999. Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95). J. Invest. Dermatol. 113: 1011-1020.
21. GIARD, D.J., S.A. AARONSON & J. TODARO. 1973. In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. Natl. Cancer Inst. 51: 1417-1423.
22. SANTEL, A. et al. 2006. A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium. Gene Ther. 13: 1222-1234.
23. BALENTIEN, E. et al. 1990. Recombinant expression, biochemical characterisation and biological activities of the human MGSA/GRO-α protein. Biochemistry 29: 10225-10233.
24. MOSER, B. et al. 1990. Neutrophil-activating properties of the melanoma growth-stimulatory activity. J. Exp. Med. 171: 1797-1802.
25. LUDWIG, A. et al. 1997. The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2. Blood 90: 4588-4597.
26. VENNER, T. et al. 1995. Interleukin-8 and melanoma growth-stimulating activity (MGSA) are induced by ultraviolet B radiation in human keratinocyte cell lines. Exp. Dermatol. 4: 138-145.
27. SOZZANI, S. et al. 1997. Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J. Immunol. 159: 1993-2000.
28. RICHMOND, A. et al. 1983. Extraction of a melanoma growth-stimulatory activity from culture medium conditioned by the Hs294T human melanoma cell line. Cancer Res. 43: 2106-2112.
29. YANG, J. & A. RICHMOND. 2001. Constitutive IB Kinase Activity Correlates with Nuclear Factor-B Activation in Human Melanoma Cells. Cancer Research 61: 4901-4909.
30. HAGHNEGAHDAR, H. et al. 2000. The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma. J. Leukoc. Biol. 67: 53-62.
31. LAZAR-MOLNAR, E. et al. 2000. Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine 12: 547-554.
32. SHIH, I.M. et al. 1994. Isolation and functional characterization of the A32 melanoma-associated antigen. Cancer Res. 54: 2514-2520.
33. LUAN, J. et al. 1997. Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression. J. Leukocyte Biol. 62: 588-597.
34. YANG, G. et al. 2006. The chemokine growth-regulated oncogene 1 (GRO-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc. Natl. Acad. Sci. USA 103: 16472-16477.
35. WANG, D. et al. 2000. MGSA/GRO-mediated melanocyte transformation involves induction of Ras expression. Oncogene 19: 4647-4659.
36. FRANCESCHI, C. et al. 2000. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann. N. Y. Acad. Sci. 908: 244-254.
37. GERLI, R. et al. 2000. Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians. Mech. Ageing Dev. 121: 37-46.
38. BRUNSGAARD, H. et al. 2003. Elevated levels of tumor necrosis factor alpha and mortality in centenarians. Am. J. Med. 115: 278-283.
39. CAPRI,M. et al. 2006. Complexity of anti-immunosenescence strategies in humans. Artif. Organs 10: 730-742.
40. FRANCESCHI, C. & M. BONAFÈ. 2003. Centenarians as a model for healthy aging. Biochem Soc Trans. 31: 457-461.
41. MARIANI, E. et al. 2002. RANTES and MIP-1alpha production by T lymphocytes, monocytes and NK cells from nonagenarian subjects. Exp. Gerontol. 37: 219-226.
42. FERRUCCI, L. et al. 1999. Serum IL-6 level and the development of disability in older persons. J. Am. Geriatr. Soc. 47: 639-646.
43. STRIETER, R.M. et al. 2004. CXC chemokines in angiogenesis of cancer. Semin. Cancer Biol. 14: 195-200.
44. BERNARDINI, G. et al. 2003. Analysis of the role of chemokines in angiogenesis. J. Immunol. Methods 273: 83-101.
45. MOORE, B.B. et al. 1998. CXC chemokines mechanism of action in regulating tumor angiogenesis. Angiogenesis 2: 123-134.
46. KARL, E. et al. 2005. Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines. Cancer Research 65: 5063-5069.
47. RICHMOND, A. et al. 2004. How do chemokine/chemokine receptor activations affect tumorigenesis? Novartis Found. Symp. 256: 74-89.
48. COPPE, J.P. et al. 2006. Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J. Biol. Chem. 281: 29568-29574.
49. KRTOLICA, A. et al. 2001 Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc. Natl. Acad. Sci. USA 98: 12072-12077.
50. PARRINELLO, S. et al. 2005. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J. Cell Sci. 118: 485-496.