Increased breakpoints on a progressive ratio schedule reinforced by IV cocaine are associated with reduced locomotor activation and reduced dopamine efflux in nucleus accumbens shell in rats

Psychopharmacology

Volumn 195, Issue 4, 2008, Pages 517-525

  Lack, Christopher M ^a   Jones, Sara R ^a   Roberts, David C S ^a  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

Addiction; Cocaine; Dopamine; Locomotor activity; Nucleus accumbens; Progressive ratio; Sensitization; Tolerance; Withdrawal

Indexed keywords

COCAINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; LOCOMOTION; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

ANIMALS; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE; MALE; MICRODIALYSIS; MOTIVATION; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT SCHEDULE; SELF ADMINISTRATION; SUBSTANCE ABUSE, INTRAVENOUS; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 36448961609     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-007-0919-4     Document Type: Article

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