Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome

Pflugers Archiv European Journal of Physiology

Volumn 455, Issue 4, 2008, Pages 637-651

  Sabir, Ian N ^a   Li, Lucia M ^a   Jones, Victoria J ^b   Goddard, Catharine A ^a   Grace, Andrew A ^a   Huang, Christopher L H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PAPWORTH HOSPITAL   (United Kingdom)

Author keywords

Action potential; Arrhythmia; Heart; Heart excitation; Heart rate; Venticular muscle; Ventricle

Indexed keywords

DNA; FLECAINIDE; QUINIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; BRUGADA SYNDROME; CONTROLLED STUDY; DIASTOLE; DNA MODIFICATION; ENDOCARDIUM; EPICARDIUM; EXTRASYSTOLE; GENETIC MODEL; HEART EXCITATION; HEART MUSCLE PERFUSION; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART STIMULATION; HEART VENTRICLE WALL; ISOLATED HEART; LONG QT SYNDROME; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; STATISTICAL ANALYSIS; WILD TYPE;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; BRUGADA SYNDROME; CARDIAC PACING, ARTIFICIAL; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; ENDOCARDIUM; FLECAINIDE; HEART RATE; LONG QT SYNDROME; MICE; MICE, TRANSGENIC; MODELS, CARDIOVASCULAR; PERFUSION; PERICARDIUM; QUINIDINE; SODIUM CHANNELS; TIME FACTORS;

EID: 36349028185     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-007-0326-z     Document Type: Article

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