메뉴 건너뛰기




Volumn 33, Issue 7, 2007, Pages 712-721

Inhibition of platelet function: Does it offer a chance of better cancer progression control?

Author keywords

Angiogenesis; Cancer; Immune surveillance; Metastasis; Platelet inhibitors; Proteolysis

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ANGIOGENESIS INHIBITOR; ARGINYLGLYCYLASPARTIC ACID; BENCYCLANE; CYPROHEPTADINE; DITAZOLE; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; GELATINASE A; GROWTH FACTOR; HEPARIN; LIPOXYGENASE INHIBITOR; LOW MOLECULAR WEIGHT HEPARIN; MONOCLONAL ANTIBODY 10E5; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEINASE ACTIVATED RECEPTOR 1; RHODOSTOMIN; RWJ 56110; SCH 79797; SNAKE VENOM; THROMBIN INHIBITOR; THROMBOPOIETIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRAPIDIL; TRIFLAVIN; TRIGRAMIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; UROKINASE RECEPTOR; VASCULOTROPIN;

EID: 36348974088     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-991540     Document Type: Review
Times cited : (109)

References (135)
  • 5
    • 0031739636 scopus 로고    scopus 로고
    • Thrombopoietin serum concentration in patients with reactive and myeloproliferative thrombocytosis
    • Uppenkamp M, Makarove E, Petrasch S, Brittinger G. Thrombopoietin serum concentration in patients with reactive and myeloproliferative thrombocytosis. Ann Hematol 1998;77:217-223
    • (1998) Ann Hematol , vol.77 , pp. 217-223
    • Uppenkamp, M.1    Makarove, E.2    Petrasch, S.3    Brittinger, G.4
  • 6
    • 0033007754 scopus 로고    scopus 로고
    • Paraneoplastic syndromes of leukocytosis, thrombocytosis, and hypercalcemia associated with squamous cell carcinoma
    • Kato N, Yasukawa K, Onozuka T, Kimura K. Paraneoplastic syndromes of leukocytosis, thrombocytosis, and hypercalcemia associated with squamous cell carcinoma. J Dermatol 1999;26:352-358
    • (1999) J Dermatol , vol.26 , pp. 352-358
    • Kato, N.1    Yasukawa, K.2    Onozuka, T.3    Kimura, K.4
  • 7
    • 0029065219 scopus 로고
    • Elevated plasma thrombopoietic activity in patients with metastatic cancer-related thrombocytosis
    • Estrov Z, Talpaz M, Mavlight G, et al. Elevated plasma thrombopoietic activity in patients with metastatic cancer-related thrombocytosis. Am J Med 1995;98:551-558
    • (1995) Am J Med , vol.98 , pp. 551-558
    • Estrov, Z.1    Talpaz, M.2    Mavlight, G.3
  • 8
    • 0027534993 scopus 로고
    • High IL-6 levels in ascitic fluid correlate with reactive thrombocytosis in patients with epithelial ovarian cancer
    • Gastl G, Plante M, Finstad CL, et al. High IL-6 levels in ascitic fluid correlate with reactive thrombocytosis in patients with epithelial ovarian cancer. Br J Haematol 1993;83:433-441
    • (1993) Br J Haematol , vol.83 , pp. 433-441
    • Gastl, G.1    Plante, M.2    Finstad, C.L.3
  • 9
    • 0026793205 scopus 로고
    • Thrombocytosis in patients with tumors producing colony-stimulating factor
    • Suzuki A, Takahashi T, Nakamura K, et al. Thrombocytosis in patients with tumors producing colony-stimulating factor. Blood 1992;80:2052-2059
    • (1992) Blood , vol.80 , pp. 2052-2059
    • Suzuki, A.1    Takahashi, T.2    Nakamura, K.3
  • 10
    • 0028864381 scopus 로고
    • Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors
    • Raffi S, Shapiro F, Pettengeli R, et al. Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors. Blood 1995;86:3353-3363
    • (1995) Blood , vol.86 , pp. 3353-3363
    • Raffi, S.1    Shapiro, F.2    Pettengeli, R.3
  • 11
    • 0036258785 scopus 로고    scopus 로고
    • Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells
    • Baj-Krzyworzeka M, Majka M, Pratico D, et al. Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells. Exp Hematol 2002;30:450-459
    • (2002) Exp Hematol , vol.30 , pp. 450-459
    • Baj-Krzyworzeka, M.1    Majka, M.2    Pratico, D.3
  • 12
    • 0033584052 scopus 로고    scopus 로고
    • Platelet counts and prognosis of pancreatic cancer
    • Schwarz RE. Platelet counts and prognosis of pancreatic cancer. Lancet 1999;353:2158-2159
    • (1999) Lancet , vol.353 , pp. 2158-2159
    • Schwarz, R.E.1
  • 14
    • 0028675817 scopus 로고
    • Adhesion molecules and tumor metastasis: An update
    • Tang DG, Honn KV. Adhesion molecules and tumor metastasis: an update. Invasion Metastasis 1994-95;14:109-122
    • (1994) Invasion Metastasis , vol.14 , pp. 109-122
    • Tang, D.G.1    Honn, K.V.2
  • 15
    • 0026996750 scopus 로고
    • Platelets and cancer metastasis: More than an epiphenomenon
    • Honn KV, Tang GT, Chen YQ. Platelets and cancer metastasis: more than an epiphenomenon. Semin Thromb Hemost 1992;18:392-415
    • (1992) Semin Thromb Hemost , vol.18 , pp. 392-415
    • Honn, K.V.1    Tang, G.T.2    Chen, Y.Q.3
  • 16
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other diseases
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other diseases. Nat Med 1995;1:27-31
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 17
  • 18
    • 1842555351 scopus 로고    scopus 로고
    • Contribution of the hemostatic system to angiogenesis in cancer
    • Wojtukiewicz MZ, Sierko E, Rak J. Contribution of the hemostatic system to angiogenesis in cancer. Semin Thromb Hemost 2004;30:5-20
    • (2004) Semin Thromb Hemost , vol.30 , pp. 5-20
    • Wojtukiewicz, M.Z.1    Sierko, E.2    Rak, J.3
  • 19
    • 26444601121 scopus 로고    scopus 로고
    • Platelet-mimicry of cancer cells: Epiphenomenon with clinical significance
    • Timår J, To̊wåri J, Råso̊ E, Mèszåros L. Platelet-mimicry of cancer cells: epiphenomenon with clinical significance. Oncology 2005;69:185-201
    • (2005) Oncology , vol.69 , pp. 185-201
    • Timår, J.1    To̊wåri, J.2    Råso̊, E.3    Mèszåros, L.4
  • 21
    • 0034916133 scopus 로고    scopus 로고
    • Platelet adhesion receptors and (patho)physiological thrombus formation
    • Andrews RK, Shen Y, Gardiner EE, Berndt MC. Platelet adhesion receptors and (patho)physiological thrombus formation. Histol Histopathol 2001;16:969-980
    • (2001) Histol Histopathol , vol.16 , pp. 969-980
    • Andrews, R.K.1    Shen, Y.2    Gardiner, E.E.3    Berndt, M.C.4
  • 22
    • 0037169552 scopus 로고    scopus 로고
    • The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in a receptor density-dependent fashion
    • Chen H, Locke D, Liu Y, Kahn ML. The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in a receptor density-dependent fashion. J Biol Chem 2002;277:3011-3019
    • (2002) J Biol Chem , vol.277 , pp. 3011-3019
    • Chen, H.1    Locke, D.2    Liu, Y.3    Kahn, M.L.4
  • 23
    • 0035748337 scopus 로고    scopus 로고
    • Platelet integrin alphaIIbbeta3-ligand interactions: What we learn from the structure?
    • Kamata T, Takada Y. Platelet integrin alphaIIbbeta3-ligand interactions: what we learn from the structure? Int J Hematol 2001;74:382-389
    • (2001) Int J Hematol , vol.74 , pp. 382-389
    • Kamata, T.1    Takada, Y.2
  • 24
    • 0032748545 scopus 로고    scopus 로고
    • Protease-activated receptors and platelet function
    • Coughlin SR. Protease-activated receptors and platelet function. Thromb Haemost 1999;82:353-356
    • (1999) Thromb Haemost , vol.82 , pp. 353-356
    • Coughlin, S.R.1
  • 25
    • 0035253835 scopus 로고    scopus 로고
    • Nucleotide receptors: An emerging family of regulatory molecules in blood cells
    • Di Virgilio F, Chiozzi P, Ferrari D, et al. Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood 2001;97:587-600
    • (2001) Blood , vol.97 , pp. 587-600
    • Di Virgilio, F.1    Chiozzi, P.2    Ferrari, D.3
  • 26
    • 0034902812 scopus 로고    scopus 로고
    • The platelet release reaction: Granules' constituents, secretion and functions
    • Rendu F, Brohard-Bohn B. The platelet release reaction: granules' constituents, secretion and functions. Platelets 2001;12:261-273
    • (2001) Platelets , vol.12 , pp. 261-273
    • Rendu, F.1    Brohard-Bohn, B.2
  • 27
    • 0025765842 scopus 로고
    • Circulating activated platelets in myeloproliferative disorders
    • Wehmeier A, Tschope D, Esser J, et al. Circulating activated platelets in myeloproliferative disorders. Thromb Res 1991;61:271-278
    • (1991) Thromb Res , vol.61 , pp. 271-278
    • Wehmeier, A.1    Tschope, D.2    Esser, J.3
  • 28
    • 0035125847 scopus 로고    scopus 로고
    • Increased soluble P-selectin in patients with hematological and breast cancer: A comparison with fibrinogen, plasminogen activator inhibitor and von Willebrand factor
    • Blann AD, Gurney M, Wadley D, Bareford D, Stonelake P, Lip GY. Increased soluble P-selectin in patients with hematological and breast cancer: a comparison with fibrinogen, plasminogen activator inhibitor and von Willebrand factor. Blood Coagul Fibrinolysis 2001;12:43-50
    • (2001) Blood Coagul Fibrinolysis , vol.12 , pp. 43-50
    • Blann, A.D.1    Gurney, M.2    Wadley, D.3    Bareford, D.4    Stonelake, P.5    Lip, G.Y.6
  • 29
    • 3142623614 scopus 로고    scopus 로고
    • Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma
    • Caine GJ, Lip GY, Stonelake PS, Ryan P, Blann AD. Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma. Thromb Haemost 2004;92:185-190
    • (2004) Thromb Haemost , vol.92 , pp. 185-190
    • Caine, G.J.1    Lip, G.Y.2    Stonelake, P.S.3    Ryan, P.4    Blann, A.D.5
  • 31
    • 0032912142 scopus 로고    scopus 로고
    • Pathophysiology of the thrombophilic state in the cancer patient
    • Falanga A, Rickles FR. Pathophysiology of the thrombophilic state in the cancer patient. Semin Thromb Hemost 1999;25:173-182
    • (1999) Semin Thromb Hemost , vol.25 , pp. 173-182
    • Falanga, A.1    Rickles, F.R.2
  • 32
    • 13244271290 scopus 로고    scopus 로고
    • Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the mein source of TF activity released from human cancer cells
    • Yu JL, Rak JW. Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the mein source of TF activity released from human cancer cells. J Thromb Haemost 2004;2:2065-2067
    • (2004) J Thromb Haemost , vol.2 , pp. 2065-2067
    • Yu, J.L.1    Rak, J.W.2
  • 34
    • 0024496750 scopus 로고
    • Involvement of platelet membrane glycoprotein Ib and glycoprotein IIb/IIIa complex in thrombin-dependent and -independent platelet aggregations induced by tumor cells
    • Kitagawa H, Yamamoto N, Yamamoto K, et al. Involvement of platelet membrane glycoprotein Ib and glycoprotein IIb/IIIa complex in thrombin-dependent and -independent platelet aggregations induced by tumor cells. Cancer Res 1989;49:537-541
    • (1989) Cancer Res , vol.49 , pp. 537-541
    • Kitagawa, H.1    Yamamoto, N.2    Yamamoto, K.3
  • 37
    • 0029153853 scopus 로고
    • Role of platelets, thrombin, integrin IIb-IIIa, fibronectin and von Willebrand factor on tumor adhesion in vitro and metastasis in vivo
    • Nierodzik ML, Klepfish A, Karpatkin S. Role of platelets, thrombin, integrin IIb-IIIa, fibronectin and von Willebrand factor on tumor adhesion in vitro and metastasis in vivo. Thromb Haemost 1995;74:282-290
    • (1995) Thromb Haemost , vol.74 , pp. 282-290
    • Nierodzik, M.L.1    Klepfish, A.2    Karpatkin, S.3
  • 38
    • 0034283997 scopus 로고    scopus 로고
    • Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions
    • McCarty OJ, Mouse SA, Bray PF, Konstantopoulos K. Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions. Blood 2000;96:1789-1797
    • (2000) Blood , vol.96 , pp. 1789-1797
    • McCarty, O.J.1    Mouse, S.A.2    Bray, P.F.3    Konstantopoulos, K.4
  • 39
    • 0035749952 scopus 로고    scopus 로고
    • Tumor cell-platelet interaction in metastatic disease
    • Felding-Habermann B. Tumor cell-platelet interaction in metastatic disease. Haemostasis 2000;31(Suppl 1):55-58
    • (2000) Haemostasis , vol.31 , Issue.SUPPL. 1 , pp. 55-58
    • Felding-Habermann, B.1
  • 40
    • 0026544316 scopus 로고
    • Is there a role for the tumor cell integrin αIIbβ3 in tumor-cell induced platelet aggregation
    • Chopra H, Timar J, Rong X, et al. Is there a role for the tumor cell integrin αIIbβ3 in tumor-cell induced platelet aggregation. Clin Exp Metastasis 1992;10:125-137
    • (1992) Clin Exp Metastasis , vol.10 , pp. 125-137
    • Chopra, H.1    Timar, J.2    Rong, X.3
  • 41
    • 0027174152 scopus 로고
    • Studies on the role of platelet eicosanoid metabolism and integrin αIIbβ3 in tumor-cell-induced platelet aggregation
    • Steinert BW, Tang DG, Grossi IM, Umbarger LA, Honn KV. Studies on the role of platelet eicosanoid metabolism and integrin αIIbβ3 in tumor-cell-induced platelet aggregation. Int J Cancer 1993;54:92-101
    • (1993) Int J Cancer , vol.54 , pp. 92-101
    • Steinert, B.W.1    Tang, D.G.2    Grossi, I.M.3    Umbarger, L.A.4    Honn, K.V.5
  • 45
    • 15244343497 scopus 로고    scopus 로고
    • Platelet-derived lysophosphatic acid supports the progression of osteolytic bone metastases in breast cancer
    • Boucharaba A, Serre C-M, Grès S, et al. Platelet-derived lysophosphatic acid supports the progression of osteolytic bone metastases in breast cancer. J Clin Invest 2004;114: 1714-1725
    • (2004) J Clin Invest , vol.114 , pp. 1714-1725
    • Boucharaba, A.1    Serre, C.-M.2    Grès, S.3
  • 46
    • 0028985039 scopus 로고
    • The effect of platelets on invasiveness and protease production of human mammary tumor cells
    • Belloc C, Lu H, Soria C, et al. The effect of platelets on invasiveness and protease production of human mammary tumor cells. Int J Cancer 1995;60:413-417
    • (1995) Int J Cancer , vol.60 , pp. 413-417
    • Belloc, C.1    Lu, H.2    Soria, C.3
  • 47
    • 0033968571 scopus 로고    scopus 로고
    • Platelet and coagulation activation with vascular endothelial growth factor generation in soft tissue sarcomas
    • Verheul HMW, Hoekman K, Lupu F, et al. Platelet and coagulation activation with vascular endothelial growth factor generation in soft tissue sarcomas. Clin Cancer Res 2000;6:166-171
    • (2000) Clin Cancer Res , vol.6 , pp. 166-171
    • Verheul, H.M.W.1    Hoekman, K.2    Lupu, F.3
  • 48
    • 2142851264 scopus 로고    scopus 로고
    • Lysophospholipid receptors: Signaling and biology
    • Ischii L, Fukushima N, Ye X, Chun J. Lysophospholipid receptors: signaling and biology. Annu Rev Biochem 2004; 73:321-354
    • (2004) Annu Rev Biochem , vol.73 , pp. 321-354
    • Ischii, L.1    Fukushima, N.2    Ye, X.3    Chun, J.4
  • 49
    • 0024428410 scopus 로고
    • Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins
    • Van Corven EJ, Groenink A, Jalink K, Eicholtz T, Moolenaar WH. Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins. Cell 1989;59:45-54
    • (1989) Cell , vol.59 , pp. 45-54
    • Van Corven, E.J.1    Groenink, A.2    Jalink, K.3    Eicholtz, T.4    Moolenaar, W.H.5
  • 50
    • 0031029290 scopus 로고    scopus 로고
    • Constitutive production and thrombin-induced relaease of vascular endothelial growth factor by human megakaryocytes and platelets
    • Möhle R, Green D, Moore MA, Nachman RL, Rafii S. Constitutive production and thrombin-induced relaease of vascular endothelial growth factor by human megakaryocytes and platelets. Proc Natl Acad Sci USA 1997;94:663-668
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 663-668
    • Möhle, R.1    Green, D.2    Moore, M.A.3    Nachman, R.L.4    Rafii, S.5
  • 51
    • 0032925155 scopus 로고    scopus 로고
    • Platelet number and interleukin-6 correlate with VEGF but not with bFGF serum levels of advanced cancer patients
    • Salgado R, Vermeulen PB, Benoy I, et al. Platelet number and interleukin-6 correlate with VEGF but not with bFGF serum levels of advanced cancer patients. Br J Cancer 1999; 80:892-897
    • (1999) Br J Cancer , vol.80 , pp. 892-897
    • Salgado, R.1    Vermeulen, P.B.2    Benoy, I.3
  • 52
    • 0031426425 scopus 로고    scopus 로고
    • Platelet transporter of vascular endothelial growth factor
    • Verheul HMW, Hoekman K, Luykx-de Bakker S, et al. Platelet transporter of vascular endothelial growth factor. Clin Cancer Res 1997;3:2187-2190
    • (1997) Clin Cancer Res , vol.3 , pp. 2187-2190
    • Verheul, H.M.W.1    Hoekman, K.2    Luykx-de Bakker, S.3
  • 53
    • 0031947050 scopus 로고    scopus 로고
    • Peripheral blood platelets express VEGF-C and VEGF which are released during platelet activation
    • Wartiovaara U, Salven P, Mikkola Heta I. Peripheral blood platelets express VEGF-C and VEGF which are released during platelet activation. Thromb Haemost 1998;80:171-175
    • (1998) Thromb Haemost , vol.80 , pp. 171-175
    • Wartiovaara, U.1    Salven, P.2    Mikkola Heta, I.3
  • 54
    • 0034984740 scopus 로고    scopus 로고
    • VEGF as a mediator of tumor-associated immunodeficiency
    • Ohm JE, Carbone DP. VEGF as a mediator of tumor-associated immunodeficiency. Immunol Res 2001;23:263-272
    • (2001) Immunol Res , vol.23 , pp. 263-272
    • Ohm, J.E.1    Carbone, D.P.2
  • 55
    • 7644237187 scopus 로고    scopus 로고
    • Tumor-host immune interactions and dendritic cell dysfunction
    • Yang L, Carbone DP. Tumor-host immune interactions and dendritic cell dysfunction. Adv Cancer Res 2004;92:13-27
    • (2004) Adv Cancer Res , vol.92 , pp. 13-27
    • Yang, L.1    Carbone, D.P.2
  • 56
    • 0033559946 scopus 로고    scopus 로고
    • Lysis of tumor cells by natural killer cells in mice is impeded by platelets
    • Nieswandt B, Hafner M, Echtenacher B, Männel DN. Lysis of tumor cells by natural killer cells in mice is impeded by platelets. Cancer Res 1999;59:1295-1300
    • (1999) Cancer Res , vol.59 , pp. 1295-1300
    • Nieswandt, B.1    Hafner, M.2    Echtenacher, B.3    Männel, D.N.4
  • 57
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-1186
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 58
    • 0034672373 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets
    • Verheul HM, Jorna AS, Hoekman K, et al. Vascular endothelial growth factor-stimulated endothelial cells promote adhesion and activation of platelets. Blood 2000;96: 4216-4221
    • (2000) Blood , vol.96 , pp. 4216-4221
    • Verheul, H.M.1    Jorna, A.S.2    Hoekman, K.3
  • 59
    • 0031742776 scopus 로고    scopus 로고
    • Evidence that platelets promote tube formation by endothelial cells on matrigel
    • Pipili-Synetos E, Papadimitriou E, Maragoudakis ME. Evidence that platelets promote tube formation by endothelial cells on matrigel. Br J Pharmacol 1998;125:1252-1257
    • (1998) Br J Pharmacol , vol.125 , pp. 1252-1257
    • Pipili-Synetos, E.1    Papadimitriou, E.2    Maragoudakis, M.E.3
  • 60
    • 32244433234 scopus 로고    scopus 로고
    • Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage
    • Kisucka J, Butterfield CE, Duda DG, et al. Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. Proc Natl Acad Sci USA 2006; 103:855-860
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 855-860
    • Kisucka, J.1    Butterfield, C.E.2    Duda, D.G.3
  • 61
    • 4444234111 scopus 로고    scopus 로고
    • The functional role of blood platelet components in angiogenesis
    • Rhee JS, Black M, Schubert U, et al. The functional role of blood platelet components in angiogenesis. Thromb Haemost 2004;92:394-402
    • (2004) Thromb Haemost , vol.92 , pp. 394-402
    • Rhee, J.S.1    Black, M.2    Schubert, U.3
  • 62
    • 20444378130 scopus 로고    scopus 로고
    • Platelet-derived microparticles induce angiogenesis and stimmulate post-ischaemic revascularization
    • Brill A, Dashevsky O, Rivo J, Gozal Y, Varon D. Platelet-derived microparticles induce angiogenesis and stimmulate post-ischaemic revascularization. Cardiovasc Res 2005;67:30-38
    • (2005) Cardiovasc Res , vol.67 , pp. 30-38
    • Brill, A.1    Dashevsky, O.2    Rivo, J.3    Gozal, Y.4    Varon, D.5
  • 63
    • 27944486056 scopus 로고    scopus 로고
    • Alteration in platelet function in patients with early breast cancer
    • McDowell G, Temple I, Li C, et al. Alteration in platelet function in patients with early breast cancer. Anticancer Res 2005;25:3963-3966
    • (2005) Anticancer Res , vol.25 , pp. 3963-3966
    • McDowell, G.1    Temple, I.2    Li, C.3
  • 64
    • 0036395643 scopus 로고    scopus 로고
    • Determination of vascular endothelial growth factor (VEGF) in circulating blood: Significance of VEGF in various leucocytes and platelets
    • Werther K, Chjritensen IJ, Nielsen HJ. Determination of vascular endothelial growth factor (VEGF) in circulating blood: significance of VEGF in various leucocytes and platelets. Scand J Clin Lab Invest 2002;62:343-350
    • (2002) Scand J Clin Lab Invest , vol.62 , pp. 343-350
    • Werther, K.1    Chjritensen, I.J.2    Nielsen, H.J.3
  • 65
    • 18344402517 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor per platelet count in hepatocellular carcinoma: Correlations with clinical parameters and survival
    • Kim SJ, Choi IK, Park KH, et al. Serum vascular endothelial growth factor per platelet count in hepatocellular carcinoma: correlations with clinical parameters and survival. Jpn J Clin Oncol 2004;34:184-190
    • (2004) Jpn J Clin Oncol , vol.34 , pp. 184-190
    • Kim, S.J.1    Choi, I.K.2    Park, K.H.3
  • 66
    • 11844276647 scopus 로고    scopus 로고
    • Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets
    • Ma L, Perini R, McKnight W, Klein A, Hollenberg MD, Wallace JL. Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets. Proc Natl Acad Sci USA 2005;102:216-220
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 216-220
    • Ma, L.1    Perini, R.2    McKnight, W.3    Klein, A.4    Hollenberg, M.D.5    Wallace, J.L.6
  • 67
    • 0026089929 scopus 로고
    • Tumour secreted vascular permeability factor increases cytosolic Ca2+ and von Willebrand factor release in human cells
    • Brock TA, Dvorak HF, Senger DR. Tumour secreted vascular permeability factor increases cytosolic Ca2+ and von Willebrand factor release in human cells. Am J Pathol 1991;138:213-221
    • (1991) Am J Pathol , vol.138 , pp. 213-221
    • Brock, T.A.1    Dvorak, H.F.2    Senger, D.R.3
  • 68
    • 0034036689 scopus 로고    scopus 로고
    • Angiopoietin-1 protects the adult vasculature against leakage
    • Thurston G, Rudge JS, Ioffe E, et al. Angiopoietin-1 protects the adult vasculature against leakage. Nat Med 2000;6:460-463
    • (2000) Nat Med , vol.6 , pp. 460-463
    • Thurston, G.1    Rudge, J.S.2    Ioffe, E.3
  • 69
    • 0025688912 scopus 로고
    • Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration
    • Clauss M, Gerlach M, Gerlach H, et al. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990;172:1535-1545
    • (1990) J Exp Med , vol.172 , pp. 1535-1545
    • Clauss, M.1    Gerlach, M.2    Gerlach, H.3
  • 70
    • 0032699085 scopus 로고    scopus 로고
    • Fibroblast growth factor prototype release and fibroblast growth factor receptor signaling
    • Friesel R, Maciag T. Fibroblast growth factor prototype release and fibroblast growth factor receptor signaling. Thromb Haemost 1999;82:748-754
    • (1999) Thromb Haemost , vol.82 , pp. 748-754
    • Friesel, R.1    Maciag, T.2
  • 71
    • 0032825703 scopus 로고    scopus 로고
    • Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF
    • Valter MM, Wietler OD, Pietsche T, Pietsch T. Differential control of VEGF synthesis and secretion in human glioma cells by IL-1 and EGF. Int J Dev Neurosci 1999; 17:565-577
    • (1999) Int J Dev Neurosci , vol.17 , pp. 565-577
    • Valter, M.M.1    Wietler, O.D.2    Pietsche, T.3    Pietsch, T.4
  • 72
    • 0344837389 scopus 로고    scopus 로고
    • Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
    • Guo P, Gu W, Xu L, et al. Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment. Am J Pathol 2003; 162:1083-1093
    • (2003) Am J Pathol , vol.162 , pp. 1083-1093
    • Guo, P.1    Gu, W.2    Xu, L.3
  • 73
    • 0037453059 scopus 로고    scopus 로고
    • Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis ets-1
    • Tomita N, Morishita R, Taniyama Y, et al. Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis ets-1. Circulation 2003;107:1411-1417
    • (2003) Circulation , vol.107 , pp. 1411-1417
    • Tomita, N.1    Morishita, R.2    Taniyama, Y.3
  • 74
    • 0033965843 scopus 로고    scopus 로고
    • Identification of angiogenic properties of insulin-like growth factor II in in vitro angiogenesis models
    • Lee OH, Bae SK, Bae MH, et al. Identification of angiogenic properties of insulin-like growth factor II in in vitro angiogenesis models. Br J Cancer 2000;82:385-391
    • (2000) Br J Cancer , vol.82 , pp. 385-391
    • Lee, O.H.1    Bae, S.K.2    Bae, M.H.3
  • 75
    • 0033951758 scopus 로고    scopus 로고
    • The insulin growth factor-1 elevates urokinase-type plasminogen activator-1 in human breast cancer cells: A new avenue for breast cancer therapy
    • Dunn SE, Tores JV, Nihei N, Barrett JC. The insulin growth factor-1 elevates urokinase-type plasminogen activator-1 in human breast cancer cells: a new avenue for breast cancer therapy. Mol Carcinog 2000;27:10-17
    • (2000) Mol Carcinog , vol.27 , pp. 10-17
    • Dunn, S.E.1    Tores, J.V.2    Nihei, N.3    Barrett, J.C.4
  • 76
    • 0037049982 scopus 로고    scopus 로고
    • Transforming growth factor-beta and Ras regulate the VEGF/VEGF-receptor system during tumor angiogenesis
    • Breier G, Blum S, Peli J, et al. Transforming growth factor-beta and Ras regulate the VEGF/VEGF-receptor system during tumor angiogenesis. Int J Cancer 2002;97:142-148
    • (2002) Int J Cancer , vol.97 , pp. 142-148
    • Breier, G.1    Blum, S.2    Peli, J.3
  • 78
    • 0035823504 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 regulates tumor growth and angiogenesis
    • McMahon GA, Petitclerc E, Stefansson S, et al. Plasminogen activator inhibitor-1 regulates tumor growth and angiogenesis. J Biol Chem 2001;276:33964-33968
    • (2001) J Biol Chem , vol.276 , pp. 33964-33968
    • McMahon, G.A.1    Petitclerc, E.2    Stefansson, S.3
  • 80
    • 0021902449 scopus 로고
    • Adenosine nucleotides, adenosine and adenine as angiogenesis factors
    • Teuscher E, Weidlich V. Adenosine nucleotides, adenosine and adenine as angiogenesis factors. Biomed Biochim Acta 1985;44:493-495
    • (1985) Biomed Biochim Acta , vol.44 , pp. 493-495
    • Teuscher, E.1    Weidlich, V.2
  • 81
    • 0033738368 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis
    • English D, Welch Z, Kovala AT, et al. Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. FASEB J 2000;14:2255-2265
    • (2000) FASEB J , vol.14 , pp. 2255-2265
    • English, D.1    Welch, Z.2    Kovala, A.T.3
  • 82
    • 0141609786 scopus 로고    scopus 로고
    • Cellular microparticles: What are they bad or good for?
    • Freyssinet JM. Cellular microparticles: what are they bad or good for? J Thromb Haemost 2003;1:1655-1662
    • (2003) J Thromb Haemost , vol.1 , pp. 1655-1662
    • Freyssinet, J.M.1
  • 83
    • 11944249676 scopus 로고    scopus 로고
    • Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer
    • Janowska-Wieczorek A, Wysoczynski M, Kijowski J, et al. Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer. Int J Cancer 2005; 113:752-760
    • (2005) Int J Cancer , vol.113 , pp. 752-760
    • Janowska-Wieczorek, A.1    Wysoczynski, M.2    Kijowski, J.3
  • 84
    • 0025147371 scopus 로고
    • A tumor supprressor-dependent inhibitor of angiogenesis is immunologically and functionally indistiguishable from a fragment of thrombospondin
    • Good DJ, Polverini PJ, Rastinejad F, et al. A tumor supprressor-dependent inhibitor of angiogenesis is immunologically and functionally indistiguishable from a fragment of thrombospondin. Proc Natl Acad Sci USA 1990; 87:6624-6628
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6624-6628
    • Good, D.J.1    Polverini, P.J.2    Rastinejad, F.3
  • 85
    • 0019949388 scopus 로고
    • Protamine is an inhibitor of angiogenesis
    • Taylor S, Folkman J. Protamine is an inhibitor of angiogenesis. Nature 1982;297:307-312
    • (1982) Nature , vol.297 , pp. 307-312
    • Taylor, S.1    Folkman, J.2
  • 86
    • 0037286698 scopus 로고    scopus 로고
    • HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model
    • Nakabayashi M, Morishita R, Nakagami H, et al. HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model. Diabetologia 2003;46:115-123
    • (2003) Diabetologia , vol.46 , pp. 115-123
    • Nakabayashi, M.1    Morishita, R.2    Nakagami, H.3
  • 87
    • 0037592684 scopus 로고    scopus 로고
    • Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production
    • Pizurki L, Zhou Z, Glynos K, Roussos C, Papapetropoulos A. Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production. Br J Pharmacol 2003;139:329-336
    • (2003) Br J Pharmacol , vol.139 , pp. 329-336
    • Pizurki, L.1    Zhou, Z.2    Glynos, K.3    Roussos, C.4    Papapetropoulos, A.5
  • 88
    • 84878096087 scopus 로고    scopus 로고
    • Generation of platelet angiostatin mediated by urokinase plasminogen activator: Effects on angiogenesis
    • Jurasz P, Santos-Martinez MJ, Radomska A, Radomski MW. Generation of platelet angiostatin mediated by urokinase plasminogen activator: effects on angiogenesis. J Thromb Haemost 2006;4:1095-1106
    • (2006) J Thromb Haemost , vol.4 , pp. 1095-1106
    • Jurasz, P.1    Santos-Martinez, M.J.2    Radomska, A.3    Radomski, M.W.4
  • 89
    • 0030946445 scopus 로고    scopus 로고
    • Release of gelatinase A during platelet activation mediates aggregation
    • Sawicki G, Salas E, Murat J, et al. Release of gelatinase A during platelet activation mediates aggregation. Nature 1997; 386:616-619
    • (1997) Nature , vol.386 , pp. 616-619
    • Sawicki, G.1    Salas, E.2    Murat, J.3
  • 90
    • 0025974768 scopus 로고
    • Modulation of endothelial cells fibrinolytic activity by platelets
    • Menashi S, He L, Soria C, et al. Modulation of endothelial cells fibrinolytic activity by platelets. Thromb Haemost 1991; 65:77-81
    • (1991) Thromb Haemost , vol.65 , pp. 77-81
    • Menashi, S.1    He, L.2    Soria, C.3
  • 91
    • 0037036679 scopus 로고    scopus 로고
    • Contribution of stromal metalloproteinase 9 to angiogenesis and growth of human ovarian carcinoma in mice
    • Huang S, Van Arsdall M, Tedjarati S, et al. Contribution of stromal metalloproteinase 9 to angiogenesis and growth of human ovarian carcinoma in mice. J Natl Cancer Inst 2002; 94:1134-1142
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1134-1142
    • Huang, S.1    Van Arsdall, M.2    Tedjarati, S.3
  • 92
    • 0034331185 scopus 로고    scopus 로고
    • Platelet release of trimolecular complex components MT1-TIMP2-MMP2: Involvement in MMP2 activation and platelet aggregation
    • Kazes I, Elalamy I, Sraer JD, et al. Platelet release of trimolecular complex components MT1-TIMP2-MMP2: involvement in MMP2 activation and platelet aggregation. Blood 2000;96:3064-3069
    • (2000) Blood , vol.96 , pp. 3064-3069
    • Kazes, I.1    Elalamy, I.2    Sraer, J.D.3
  • 93
    • 0026722647 scopus 로고
    • Expression of heparanase by platelets and circulating cells of the immune system: Possible involvement in diapedesis and extravasation
    • Vlodavsky I, Eldor A, Haimovitz-Friedman A, et al. Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation. Invasion Metastasis 1992;12:112-127
    • (1992) Invasion Metastasis , vol.12 , pp. 112-127
    • Vlodavsky, I.1    Eldor, A.2    Haimovitz-Friedman, A.3
  • 94
    • 0020619733 scopus 로고
    • A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombastenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa
    • Coller BS, Peerschke EL, Scudder LE, Sullivan CA. A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombastenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa. J Clin Invest 1983;72:325-328
    • (1983) J Clin Invest , vol.72 , pp. 325-328
    • Coller, B.S.1    Peerschke, E.L.2    Scudder, L.E.3    Sullivan, C.A.4
  • 95
    • 0034918474 scopus 로고    scopus 로고
    • Anti-GpIIb/IIIa drugs: Current strategies and future directions
    • Coller BS. Anti-GpIIb/IIIa drugs: current strategies and future directions. Thromb Haemost 2001;86:427-443
    • (2001) Thromb Haemost , vol.86 , pp. 427-443
    • Coller, B.S.1
  • 96
    • 0037092984 scopus 로고    scopus 로고
    • Trikha M, Zhou Z, Timar J, et al. Multiple roles for platelet GPIIb/IIa and platelet alpha v beta 3 integrins in tumor growth, angiogenesis, and metastasis. Cancer Res 2002;62: 2824-2833
    • Trikha M, Zhou Z, Timar J, et al. Multiple roles for platelet GPIIb/IIa and platelet alpha v beta 3 integrins in tumor growth, angiogenesis, and metastasis. Cancer Res 2002;62: 2824-2833
  • 97
    • 0032836245 scopus 로고    scopus 로고
    • Blockade of GpIIb/IIIa inhibits the release of vascular endothelial growth factor (VEGF) from tumor-cell-activated platelets and experimental metastasis
    • Amirkhosravi A, Amaya M, Siddiqui F, et al. Blockade of GpIIb/IIIa inhibits the release of vascular endothelial growth factor (VEGF) from tumor-cell-activated platelets and experimental metastasis. Platelets 1999;10:285-292
    • (1999) Platelets , vol.10 , pp. 285-292
    • Amirkhosravi, A.1    Amaya, M.2    Siddiqui, F.3
  • 99
    • 0032941869 scopus 로고    scopus 로고
    • Actions of heparins that may affect the malignant process
    • Engelberg H. Actions of heparins that may affect the malignant process. Cancer 1999;85:257-272
    • (1999) Cancer , vol.85 , pp. 257-272
    • Engelberg, H.1
  • 100
    • 0141651848 scopus 로고    scopus 로고
    • Inhibition of tumor cell-induced platelet aggregation and lung metastasis by the oral GpIIb-IIIa antagonist XV454
    • Amirkhosravi A, Mousa SA, Amaya M, et al. Inhibition of tumor cell-induced platelet aggregation and lung metastasis by the oral GpIIb-IIIa antagonist XV454. Thromb Haemost 2003;90:549-554
    • (2003) Thromb Haemost , vol.90 , pp. 549-554
    • Amirkhosravi, A.1    Mousa, S.A.2    Amaya, M.3
  • 101
    • 0026633893 scopus 로고
    • Triflavin, an Arg-Gly-Asp containing snake venom peptide, inhibits aggregation of human platelets induced by human hepatoma cell line
    • Sheu JR, Lin CH, Chung JI, Teng CM, Huang TF. Triflavin, an Arg-Gly-Asp containing snake venom peptide, inhibits aggregation of human platelets induced by human hepatoma cell line. Thromb Res 1992;66:679-691
    • (1992) Thromb Res , vol.66 , pp. 679-691
    • Sheu, J.R.1    Lin, C.H.2    Chung, J.I.3    Teng, C.M.4    Huang, T.F.5
  • 102
    • 0028238538 scopus 로고
    • Characterization of platelet aggregation induced by human colon adenocarcinoma cells and its inhibition by snake venom peptides, trigramin and rhodostomin
    • Chiang HS, Swaim MW, Huang TF. Characterization of platelet aggregation induced by human colon adenocarcinoma cells and its inhibition by snake venom peptides, trigramin and rhodostomin. BrJ Haematol 1994;87:325-331
    • (1994) BrJ Haematol , vol.87 , pp. 325-331
    • Chiang, H.S.1    Swaim, M.W.2    Huang, T.F.3
  • 103
    • 0028838003 scopus 로고
    • The Arg-Gly-Asp-containing peptide, rhodostomin, inhibits in vitro cell adhesion to extracellular matrices and platelet aggregation caused by saos-2 human osteosarcoma cells
    • Chiang HS, Swaim MW, Huang TF. The Arg-Gly-Asp-containing peptide, rhodostomin, inhibits in vitro cell adhesion to extracellular matrices and platelet aggregation caused by saos-2 human osteosarcoma cells. Br J Cancer 1995;71:265-270
    • (1995) Br J Cancer , vol.71 , pp. 265-270
    • Chiang, H.S.1    Swaim, M.W.2    Huang, T.F.3
  • 104
    • 0028950394 scopus 로고
    • Characterization of platelet aggregation induced by human breast carcinoma and its inhibition by snake venom peptides, trigramin and rhodostomin
    • Chiang HS, Swaim MW, Huang TF. Characterization of platelet aggregation induced by human breast carcinoma and its inhibition by snake venom peptides, trigramin and rhodostomin. Breast Cancer Res Treat 1995;33:225-235
    • (1995) Breast Cancer Res Treat , vol.33 , pp. 225-235
    • Chiang, H.S.1    Swaim, M.W.2    Huang, T.F.3
  • 105
    • 0036463453 scopus 로고    scopus 로고
    • Novel drug development opportunities for heparin
    • Lever R, Page CP. Novel drug development opportunities for heparin. Nat Rev Drug Discov 2002;1:140-148
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 140-148
    • Lever, R.1    Page, C.P.2
  • 106
    • 0347659492 scopus 로고    scopus 로고
    • Heparin modulates integrin-mediated cellular adhesion: Specificity of interaction with alpha and beta integrin subunits
    • da Silva MS, Horton JA, Wijelath JM, et al. Heparin modulates integrin-mediated cellular adhesion: specificity of interaction with alpha and beta integrin subunits. Cell Adhes Commun 2003;10:59-67
    • (2003) Cell Adhes Commun , vol.10 , pp. 59-67
    • da Silva, M.S.1    Horton, J.A.2    Wijelath, J.M.3
  • 107
    • 0035853111 scopus 로고    scopus 로고
    • Heparin and cancer revised: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
    • Borsig L, Wong R, Feramisco J, et al. Heparin and cancer revised: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis. Proc Natl Acad Sci USA 2001;98:3352-3357
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3352-3357
    • Borsig, L.1    Wong, R.2    Feramisco, J.3
  • 108
    • 16544390675 scopus 로고    scopus 로고
    • Endothelial P-selectin as a target of heparinb action in experimental melanoma lung metastasis
    • Ludwig RJ, Beohme B, Podda M, et al. Endothelial P-selectin as a target of heparinb action in experimental melanoma lung metastasis. Cancer Res 2004;64:2743-2750
    • (2004) Cancer Res , vol.64 , pp. 2743-2750
    • Ludwig, R.J.1    Beohme, B.2    Podda, M.3
  • 109
    • 36348946664 scopus 로고    scopus 로고
    • Low molecular weight heparin and survival in cancer
    • Kakkar AK. Low molecular weight heparin and survival in cancer. Haematological Rep 2005;1:27
    • (2005) Haematological Rep , vol.1 , pp. 27
    • Kakkar, A.K.1
  • 110
    • 0035871811 scopus 로고    scopus 로고
    • Antiplatelet agents in tissue factor-induced blood coagulation
    • Butenas S, Cawthern K, Veer C, et al. Antiplatelet agents in tissue factor-induced blood coagulation. Blood 2001;97: 2314-2322
    • (2001) Blood , vol.97 , pp. 2314-2322
    • Butenas, S.1    Cawthern, K.2    Veer, C.3
  • 111
    • 0033000420 scopus 로고    scopus 로고
    • Large amounts of vascular endothelial growth factor at the site of hemostatic plug formation in vivo
    • Waltermann A, Wolzt M, Petersmann K, et al. Large amounts of vascular endothelial growth factor at the site of hemostatic plug formation in vivo. Arterioscler Thromb Vasc Biol 1999;19:1757-1760
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1757-1760
    • Waltermann, A.1    Wolzt, M.2    Petersmann, K.3
  • 113
    • 0027491551 scopus 로고
    • Triflavin, an Arg-Gly-Asp-containing peptide, inhibits tumor cell-induced platelet aggregation
    • Sheu JR, Lin CH, Pung HC, Teng CM, Huang TF. Triflavin, an Arg-Gly-Asp-containing peptide, inhibits tumor cell-induced platelet aggregation. Jpn J Cancer Res 1993;84:1062-1071
    • (1993) Jpn J Cancer Res , vol.84 , pp. 1062-1071
    • Sheu, J.R.1    Lin, C.H.2    Pung, H.C.3    Teng, C.M.4    Huang, T.F.5
  • 115
    • 3543121913 scopus 로고    scopus 로고
    • Protease-activated receptors (PAR-1 and PAR-2) contribute to tumor cell motility and metastasis
    • Shi X, Gangedharan B, Brass LF, Ruf W, Mueller BM. Protease-activated receptors (PAR-1 and PAR-2) contribute to tumor cell motility and metastasis. Mol Cancer Res 2004;2:395-402
    • (2004) Mol Cancer Res , vol.2 , pp. 395-402
    • Shi, X.1    Gangedharan, B.2    Brass, L.F.3    Ruf, W.4    Mueller, B.M.5
  • 116
    • 33745231782 scopus 로고    scopus 로고
    • Blockage of angiogenesis by small molecule antagonists to protease-activated receptor-1: Association with endothelial cell growth suppression and induction of apoptosis
    • Zania P, Kritikou S, Flordellis CS, Maragoudakis ME, Tsopanoglou NE. Blockage of angiogenesis by small molecule antagonists to protease-activated receptor-1: association with endothelial cell growth suppression and induction of apoptosis. J Pharmacol Exp Ther 2006;318: 246-254
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 246-254
    • Zania, P.1    Kritikou, S.2    Flordellis, C.S.3    Maragoudakis, M.E.4    Tsopanoglou, N.E.5
  • 117
    • 0035475987 scopus 로고    scopus 로고
    • The role of the coagulation system in tumour angiogemesis
    • Nash GF, Walsh DC, Kakkar AK. The role of the coagulation system in tumour angiogemesis. Lancet Oncol 2001;2:608-613
    • (2001) Lancet Oncol , vol.2 , pp. 608-613
    • Nash, G.F.1    Walsh, D.C.2    Kakkar, A.K.3
  • 118
    • 0026438060 scopus 로고
    • Clinical significance of prostacyclin and thromboxane in cancer of the female breast and genital tract
    • Nigam S, Zakrzewic A, Eskafi S, Roscher A. Clinical significance of prostacyclin and thromboxane in cancer of the female breast and genital tract. Cancer Metastasis Rev 1992;11:411-420
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 411-420
    • Nigam, S.1    Zakrzewic, A.2    Eskafi, S.3    Roscher, A.4
  • 119
    • 1542379730 scopus 로고    scopus 로고
    • Differential expression of thromboxane synthase in prostate carcinoma: Role in tumor cell motility
    • Nie D, Che M, Zacharek A, et al. Differential expression of thromboxane synthase in prostate carcinoma: role in tumor cell motility. Am J Pathol 2004;164:429-439
    • (2004) Am J Pathol , vol.164 , pp. 429-439
    • Nie, D.1    Che, M.2    Zacharek, A.3
  • 121
    • 17344366112 scopus 로고    scopus 로고
    • BMD188, a novel hydroxamic acid compound, demonstrates potent an prostate cancer effects in vitro and in vivo by inducing apoptosis: Requirements for mitochondria, reactive oxygen species, and proteases
    • Tang DG, Li L, Zhu Z, et al. BMD188, a novel hydroxamic acid compound, demonstrates potent an prostate cancer effects in vitro and in vivo by inducing apoptosis: requirements for mitochondria, reactive oxygen species, and proteases. Pathol Oncol Res 1998;4:179-190
    • (1998) Pathol Oncol Res , vol.4 , pp. 179-190
    • Tang, D.G.1    Li, L.2    Zhu, Z.3
  • 122
    • 0015784395 scopus 로고
    • Platelet tumor interactions in mice. The role of platelets in spread of malignant diseases
    • Gasic GJ, Gasic TB, Galanti N, Johnson T, Murphy S. Platelet tumor interactions in mice. The role of platelets in spread of malignant diseases. Int J Cancer 1973;11:704-718
    • (1973) Int J Cancer , vol.11 , pp. 704-718
    • Gasic, G.J.1    Gasic, T.B.2    Galanti, N.3    Johnson, T.4    Murphy, S.5
  • 123
    • 0015530131 scopus 로고
    • Aspirin and tumor metastasis
    • Wood S Jr, Hilgard P. Aspirin and tumor metastasis. Lancet 1972;2:1416-1417
    • (1972) Lancet , vol.2 , pp. 1416-1417
    • Wood Jr, S.1    Hilgard, P.2
  • 125
    • 0022557060 scopus 로고
    • Effect of tromboxane A2 inhibition on osteogenic sarcoma cell-induced platelet aggregation
    • Mehta P, Lawson D, Ward MB, Lee-Ambrose L, Kimura A. Effect of tromboxane A2 inhibition on osteogenic sarcoma cell-induced platelet aggregation. Cancer Res 1986; 46:5061-5063
    • (1986) Cancer Res , vol.46 , pp. 5061-5063
    • Mehta, P.1    Lawson, D.2    Ward, M.B.3    Lee-Ambrose, L.4    Kimura, A.5
  • 126
    • 0021262408 scopus 로고
    • Effects of antiplatelet agents on pulmonary metastases
    • Bando H, Yamashita T, Tsubura E. Effects of antiplatelet agents on pulmonary metastases. Gann 1984;75:284-291
    • (1984) Gann , vol.75 , pp. 284-291
    • Bando, H.1    Yamashita, T.2    Tsubura, E.3
  • 127
    • 0017807439 scopus 로고
    • Effect of diltazole, an inhibitor of platelet aggregation, on a metastasizing tumor in mice
    • Mussoni L, Poggi A, De Gaetano G, Donati MB. Effect of diltazole, an inhibitor of platelet aggregation, on a metastasizing tumor in mice. Br J Cancer 1978;37:126-129
    • (1978) Br J Cancer , vol.37 , pp. 126-129
    • Mussoni, L.1    Poggi, A.2    De Gaetano, G.3    Donati, M.B.4
  • 128
    • 0017123908 scopus 로고
    • The influence of platelet aggregation inhibitors on metastasis formation in mice (3LL). Z Krebsforsch Klin Onkol
    • Hilgard P, Heller H, Schmidt CG. The influence of platelet aggregation inhibitors on metastasis formation in mice (3LL). Z Krebsforsch Klin Onkol Cancer Res Clin Oncol 1976;86:243-250
    • (1976) Cancer Res Clin Oncol , vol.86 , pp. 243-250
    • Hilgard, P.1    Heller, H.2    Schmidt, C.G.3
  • 130
    • 0024308397 scopus 로고
    • The pyrimidopyrimidines derivatives RA233 and RX-RA85 affect cell cycle distribution of two murine tumour cell lines
    • Lichtner RB, Hutchinson G, Hellmann K. The pyrimidopyrimidines derivatives RA233 and RX-RA85 affect cell cycle distribution of two murine tumour cell lines. Eur J Cancer Clin Oncol 1989;25:945-951
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 945-951
    • Lichtner, R.B.1    Hutchinson, G.2    Hellmann, K.3
  • 131
    • 0023239564 scopus 로고
    • Failure of orally administered RA233 to influence B16 melanoma growth or metastasis
    • Stackpole CW, Fornabaio DM, Alterman AL. Failure of orally administered RA233 to influence B16 melanoma growth or metastasis. Clin Exp Metastasis 1987;5:165-180
    • (1987) Clin Exp Metastasis , vol.5 , pp. 165-180
    • Stackpole, C.W.1    Fornabaio, D.M.2    Alterman, A.L.3
  • 132
    • 0020495057 scopus 로고
    • Effect of DRA233 alone and combined with radiation on experimental tumour metastasis. Part 1
    • Li XT, Hellmann K. Effect of DRA233 alone and combined with radiation on experimental tumour metastasis. Part 1. Clin Exp Metastasis 1983;1:51-59
    • (1983) Clin Exp Metastasis , vol.1 , pp. 51-59
    • Li, X.T.1    Hellmann, K.2
  • 133
    • 0021061661 scopus 로고
    • Modification of metastasis formation by inhibition of platelet aggregation. Experimental and clinical results
    • Gastpar H. Modification of metastasis formation by inhibition of platelet aggregation. Experimental and clinical results. Laryngol Rhinol Otol (Stuttg) 1983;62:578-585
    • (1983) Laryngol Rhinol Otol (Stuttg) , vol.62 , pp. 578-585
    • Gastpar, H.1
  • 134
    • 0019821905 scopus 로고    scopus 로고
    • Kohga S, Kinjo M, Tanaka K, Ogawa H, Ishihara M, Tanaka N. Effects of 5-(2-chlorobenzyl)-4,5,6,7,-tetrahydrothieno[3,2-C]pyridine hydrochloride (ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis. Cancer Res 1981;41:4710-4714
    • Kohga S, Kinjo M, Tanaka K, Ogawa H, Ishihara M, Tanaka N. Effects of 5-(2-chlorobenzyl)-4,5,6,7,-tetrahydrothieno[3,2-C]pyridine hydrochloride (ticlopidine), a platelet aggregation inhibitor, on blood-borne metastasis. Cancer Res 1981;41:4710-4714


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.